Muhammad Aneel Razzaq, Muhammad Atif, Ubaid Ullah, Mohsin Mehmood, Muhammad Irfan, Kashif Sardar
{"title":"慢性阻塞性肺病急性加重期患者心房颤动的风险","authors":"Muhammad Aneel Razzaq, Muhammad Atif, Ubaid Ullah, Mohsin Mehmood, Muhammad Irfan, Kashif Sardar","doi":"10.37185/lns.1.1.487","DOIUrl":null,"url":null,"abstract":"Objective: To evaluate the role of acute exacerbation of COPD in the risk of atrial fibrillation. Study Design: Cross sectional study design.Place and Duration of Study: The study was conducted at Bakhtawar Amin Hospital Multan and Recep Tayyip Erdogan Hospital Muzaffargarh, Pakistan from March 2022 to March 2023.Methods: The patients with acute, hypercapnic chronic obstructive pulmonary disease(COPD) exacerbation were included in the study. A total of 200 patients were analyzed. Baseline data including demographic and clinical details, blood tests, ABG, systolic and diastolic blood pressure, ECG, pulmonary function test, and transthoracic echocardiography were recorded.Results: Of 200 patients, 40(20%) had an episode of paroxysmal atrial fibrillation (AF). Atrial fibrillation was more prevalent in cases with lower FEV1 (P<.05). In addition, it was also more common in cases with higher PaCO2 (P<.05). Atrial Fibrillation was significantly higher in cases with larger LA diameters (34.1 ± 2.3 mm vs 46.1 ± 2.3 mm, P<.05), area (22.8 ± 4.1 cm2 vs 34.1 ± 5.1 cm2, P<.05) and higher PASP (36.1 mmHg ± 2.2 vs 46.4 mmHg ± 3.7, P<.05). RA area was larger in patients with AF and COPD compared to those without AF (25.6 ± 5.1cm2 vs 30.2 ± 6.4 cm2, P<0.05). These findings suggest COPD patients are at increased risk of AF and require measures to reduce the risk. These data will be helpful for further investigation and development of strategies to prevent AF morbidities in COPD patients.Conclusion: In patients with acute exacerbations of chronic obstructive pulmonary disease, blood gas fluctuations, hemodynamic alterations, and abnormal pulmonary functions can lead to an increased risk of atrial fibrillation. \nHow to cite this: Razzaq MA, Atif M, Ullah U, Mehmood M, Irfan M, Sardar K. The Risk of Atrial Fibrillation in Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease. Life and Science. 2024; 5(2): 132-137. doi: http://doi.org/10.37185/LnS.1.1.487","PeriodicalId":516717,"journal":{"name":"Life and Science","volume":" 45","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"The Risk of Atrial Fibrillation in Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease\",\"authors\":\"Muhammad Aneel Razzaq, Muhammad Atif, Ubaid Ullah, Mohsin Mehmood, Muhammad Irfan, Kashif Sardar\",\"doi\":\"10.37185/lns.1.1.487\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Objective: To evaluate the role of acute exacerbation of COPD in the risk of atrial fibrillation. Study Design: Cross sectional study design.Place and Duration of Study: The study was conducted at Bakhtawar Amin Hospital Multan and Recep Tayyip Erdogan Hospital Muzaffargarh, Pakistan from March 2022 to March 2023.Methods: The patients with acute, hypercapnic chronic obstructive pulmonary disease(COPD) exacerbation were included in the study. A total of 200 patients were analyzed. Baseline data including demographic and clinical details, blood tests, ABG, systolic and diastolic blood pressure, ECG, pulmonary function test, and transthoracic echocardiography were recorded.Results: Of 200 patients, 40(20%) had an episode of paroxysmal atrial fibrillation (AF). Atrial fibrillation was more prevalent in cases with lower FEV1 (P<.05). In addition, it was also more common in cases with higher PaCO2 (P<.05). Atrial Fibrillation was significantly higher in cases with larger LA diameters (34.1 ± 2.3 mm vs 46.1 ± 2.3 mm, P<.05), area (22.8 ± 4.1 cm2 vs 34.1 ± 5.1 cm2, P<.05) and higher PASP (36.1 mmHg ± 2.2 vs 46.4 mmHg ± 3.7, P<.05). RA area was larger in patients with AF and COPD compared to those without AF (25.6 ± 5.1cm2 vs 30.2 ± 6.4 cm2, P<0.05). These findings suggest COPD patients are at increased risk of AF and require measures to reduce the risk. These data will be helpful for further investigation and development of strategies to prevent AF morbidities in COPD patients.Conclusion: In patients with acute exacerbations of chronic obstructive pulmonary disease, blood gas fluctuations, hemodynamic alterations, and abnormal pulmonary functions can lead to an increased risk of atrial fibrillation. \\nHow to cite this: Razzaq MA, Atif M, Ullah U, Mehmood M, Irfan M, Sardar K. The Risk of Atrial Fibrillation in Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease. Life and Science. 2024; 5(2): 132-137. doi: http://doi.org/10.37185/LnS.1.1.487\",\"PeriodicalId\":516717,\"journal\":{\"name\":\"Life and Science\",\"volume\":\" 45\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-05-03\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Life and Science\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.37185/lns.1.1.487\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Life and Science","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.37185/lns.1.1.487","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
目的：评估慢性阻塞性肺病急性加重对心房颤动风险的影响：评估慢性阻塞性肺病急性加重对心房颤动风险的影响。研究设计横断面研究设计：研究地点和时间：2022 年 3 月至 2023 年 3 月，在巴基斯坦木尔坦市巴赫塔瓦尔-阿明医院和穆扎法格尔市雷杰普-塔伊普-埃尔多安医院进行：研究对象包括急性、高碳酸血症慢性阻塞性肺疾病（COPD）加重的患者。共对 200 名患者进行了分析。记录的基线数据包括人口统计学和临床详情、血液化验、ABG、收缩压和舒张压、心电图、肺功能测试和经胸超声心动图：在 200 名患者中，有 40 人（20%）发作过阵发性心房颤动（房颤）。心房颤动在 FEV1 较低的病例中更为常见（P<.05）。此外，PaCO2 较高的病例也更容易发生心房颤动（P<.05）。在 LA 直径（34.1 ± 2.3 mm vs 46.1 ± 2.3 mm，P<.05）、面积（22.8 ± 4.1 cm2 vs 34.1 ± 5.1 cm2，P<.05）和 PASP（36.1 mmHg ± 2.2 vs 46.4 mmHg ± 3.7，P<.05）较大的病例中，心房颤动的发生率明显较高。与无房颤患者相比，房颤合并慢性阻塞性肺病患者的 RA 面积更大（25.6 ± 5.1 cm2 vs 30.2 ± 6.4 cm2，P<0.05）。这些研究结果表明，慢性阻塞性肺病患者罹患房颤的风险增加，需要采取措施降低风险。这些数据将有助于进一步调查和制定预防慢性阻塞性肺病患者房颤发病的策略：慢性阻塞性肺疾病急性加重期患者的血气波动、血流动力学改变和肺功能异常可导致房颤风险增加。 引用方式Razzaq MA, Atif M, Ullah U, Mehmood M, Irfan M, Sardar K. The Risk of Atrial Fibrillation in Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease.生命与科学2024; 5(2):132-137. doi: http://doi.org/10.37185/LnS.1.1.487
The Risk of Atrial Fibrillation in Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease
Objective: To evaluate the role of acute exacerbation of COPD in the risk of atrial fibrillation. Study Design: Cross sectional study design.Place and Duration of Study: The study was conducted at Bakhtawar Amin Hospital Multan and Recep Tayyip Erdogan Hospital Muzaffargarh, Pakistan from March 2022 to March 2023.Methods: The patients with acute, hypercapnic chronic obstructive pulmonary disease(COPD) exacerbation were included in the study. A total of 200 patients were analyzed. Baseline data including demographic and clinical details, blood tests, ABG, systolic and diastolic blood pressure, ECG, pulmonary function test, and transthoracic echocardiography were recorded.Results: Of 200 patients, 40(20%) had an episode of paroxysmal atrial fibrillation (AF). Atrial fibrillation was more prevalent in cases with lower FEV1 (P<.05). In addition, it was also more common in cases with higher PaCO2 (P<.05). Atrial Fibrillation was significantly higher in cases with larger LA diameters (34.1 ± 2.3 mm vs 46.1 ± 2.3 mm, P<.05), area (22.8 ± 4.1 cm2 vs 34.1 ± 5.1 cm2, P<.05) and higher PASP (36.1 mmHg ± 2.2 vs 46.4 mmHg ± 3.7, P<.05). RA area was larger in patients with AF and COPD compared to those without AF (25.6 ± 5.1cm2 vs 30.2 ± 6.4 cm2, P<0.05). These findings suggest COPD patients are at increased risk of AF and require measures to reduce the risk. These data will be helpful for further investigation and development of strategies to prevent AF morbidities in COPD patients.Conclusion: In patients with acute exacerbations of chronic obstructive pulmonary disease, blood gas fluctuations, hemodynamic alterations, and abnormal pulmonary functions can lead to an increased risk of atrial fibrillation.
How to cite this: Razzaq MA, Atif M, Ullah U, Mehmood M, Irfan M, Sardar K. The Risk of Atrial Fibrillation in Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease. Life and Science. 2024; 5(2): 132-137. doi: http://doi.org/10.37185/LnS.1.1.487
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