Journal of Robotics and Mechatronics最新文献_第6页

Control of Osmotic-Engine-Driven Liposomes Using Biological Nanopores 利用生物纳米孔控制渗透发动机驱动的脂质体

Journal of Robotics and Mechatronics Pub Date : 2023-10-20 DOI: 10.20965/jrm.2023.p1213

Hinata Shibuya, Shun Okada, Kan Shoji

{"title":"Control of Osmotic-Engine-Driven Liposomes Using Biological Nanopores","authors":"Hinata Shibuya, Shun Okada, Kan Shoji","doi":"10.20965/jrm.2023.p1213","DOIUrl":"https://doi.org/10.20965/jrm.2023.p1213","url":null,"abstract":"Liposome-based molecular robots that molecular systems are integrated into a giant liposome have been proposed; they are expected to be applied in the fields of medicine, environmental science, food science, and energy science. However, the performance of these molecular robotic components, including intelligence, sensors, and actuators, still hinders their practical use. In particular, the actuators used in the molecular robots, such as molecular motors, do not provide sufficient performance to move the giant liposomes. Hence, we propose an osmotic-engine-driven liposome and demonstrate the migration of liposomes in a microfluidic channel by applying a salt concentration difference between the front and rear of the liposome. Although the migration mechanism is simple and has the potential to provide sufficient mobility performance, control techniques for the movement speed and on/off switching are not established. Herein, we describe a speed control method of osmotic-engine-driven liposomes using pore-forming membrane proteins. In this study, we evaluated the effect of reconstituted α-hemolysin (αHL) nanopores on the water permeability through lipid bilayers. Thereafter, we demonstrated the change in displacement speeds of liposomes with and without nanopores. We expect the speed control method using nanopores to be applied to the liposome-based molecular robots.","PeriodicalId":51661,"journal":{"name":"Journal of Robotics and Mechatronics","volume":"45 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135568014","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Special Issue on Bio-MEMS 生物mems特刊

Journal of Robotics and Mechatronics Pub Date : 2023-10-20 DOI: 10.20965/jrm.2023.p1121

Shoichiro Fujisawa, Katsuya Sato, Kazuyuki Minami, Kazuaki Nagayama, Ryo Sudo, Hiromi Miyoshi, Yuta Nakashima, Kennedy Omondi Okeyo, Tasuku Nakahara

{"title":"Special Issue on Bio-MEMS","authors":"Shoichiro Fujisawa, Katsuya Sato, Kazuyuki Minami, Kazuaki Nagayama, Ryo Sudo, Hiromi Miyoshi, Yuta Nakashima, Kennedy Omondi Okeyo, Tasuku Nakahara","doi":"10.20965/jrm.2023.p1121","DOIUrl":"https://doi.org/10.20965/jrm.2023.p1121","url":null,"abstract":"A Micro Electro-Mechanical System (MEMS) is a micro-sized mechatronic device based on semiconductor integrated-circuit manufacturing technology. MEMS technology is inherently a very powerful tool for researchers to manipulate and measure the microscopic biological components of biological tissues since their basic constituent units, cells and intracellular microstructures, are also micron or even submicron in size. MEMS technology applied to medicine and life sciences is called Bio-MEMS. Many Bio-MEMS devices and technologies have been developed in recent years, including microfluidic devices for cell culture, manipulation, and measurement, as well as lab-on-a-chip devices for chemical reactions and analyses on MEMS devices. This special issue consists of 13 papers: 1 review article, 1 letter, and 11 research papers. These papers include studies on mechanical stress on cells using MEMS devices, the control of cell functions through microfabrication techniques, cell measurement and in vivo microenvironment simulation using microfluidic devices, and basic research on wearable devices and self-assembling microstructures using MEMS technologies. The editorial committee members are confident that this special issue will make a significant contribution to the further development of Bio-MEMS. We sincerely appreciate the excellent contributions of the authors and the time and effort of the reviewers. We would also like to thank the editorial board of the Journal of Robotics and Mechatronics for their support of this special issue.","PeriodicalId":51661,"journal":{"name":"Journal of Robotics and Mechatronics","volume":"68 2","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135567134","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Development of a Microfluidic Ion Current Measurement System for Single-Microplastic Detection 单微塑料检测微流控离子电流测量系统的研制

Journal of Robotics and Mechatronics Pub Date : 2023-10-20 DOI: 10.20965/jrm.2023.p1193

Yuta Kishimoto, Sachiko Ide, Toyohiro Naito, Yuta Nakashima, Yoshitaka Nakanishi, Noritada Kaji

{"title":"Development of a Microfluidic Ion Current Measurement System for Single-Microplastic Detection","authors":"Yuta Kishimoto, Sachiko Ide, Toyohiro Naito, Yuta Nakashima, Yoshitaka Nakanishi, Noritada Kaji","doi":"10.20965/jrm.2023.p1193","DOIUrl":"https://doi.org/10.20965/jrm.2023.p1193","url":null,"abstract":"Microplastics (MPs) can adsorb heavy metals and metalloids and may cause a potential health hazard. Precise measurements of their size, shape, composition, and concentration at a single-MP level are important to evaluate their potential toxicity and identify their original source. However, current single-MP analytical methods such as micro-Raman spectroscopy and scanning electron microscopy have low throughput. Therefore, in this study, we applied the ion current sensing method, which has been used for single cell analysis, to single-MP analysis and examined whether size measurement and composition analysis of MPs at the single particle level are possible. In single-MP measurements, plastic particles must be mono-dispersed in solution at least within the measurement time. The agglomeration behavior was carefully observed after adding sodium dodecyl sulfate to tris-borate-EDTA buffer at 2–16 mM. Under these conditions, the size of polystyrene beads could be measured using the ion current sensing under the mono-dispersed condition. Next, ion current sensing was performed on four pseudo MPs fabricated from different materials (polyethylene, polyethylene terephthalate, polypropylene, and polyvinyl chloride) that were mechanically grazed and UV-irradiated to imitate real marine MPs. Although significant differences in the ion current signals from different material MPs were not observed, fast (100 MPs within 2 s) and precise measurements in the MPs’ sizes at a single-MP level were successfully achieved.","PeriodicalId":51661,"journal":{"name":"Journal of Robotics and Mechatronics","volume":"69 2","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135567136","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Image-Based Gel Encapsulation of Suspended Single Cells for Parallel Single-Cell Screening 基于图像的悬浮单细胞凝胶包封技术用于单细胞平行筛选

Journal of Robotics and Mechatronics Pub Date : 2023-10-20 DOI: 10.20965/jrm.2023.p1177

Venkatesh Kumar Panneer Selvam, Muhammad Luqman Arief Bin Kamaludin, Ghulam Murtaza, Rifat Hussain Chowdhury, Tanmay Debnath, Shunya Okamoto, Takayuki Shibata, Tuhin Subhra Santra, Moeto Nagai

引用次数: 0

Adaptive Kinematic Control of Underwater Cable-Driven Parallel Robot 水下索驱动并联机器人的自适应运动控制

Journal of Robotics and Mechatronics Pub Date : 2023-10-20 DOI: 10.20965/jrm.2023.p1300

Katutoshi Kodama, Akihiro Morinaga, Ikuo Yamamoto

引用次数: 0

Development of Compact 3-Degree-of-Freedom Oscillatory Actuator 紧凑型三自由度振荡作动器的研制

Journal of Robotics and Mechatronics Pub Date : 2023-10-20 DOI: 10.20965/jrm.2023.p1312

Akira Heya, Ryosuke Nakamura, Katsuhiro Hirata

引用次数: 0

Analysis of Inward Vascular Remodeling Focusing on Endothelial–Perivascular Crosstalk in a Microfluidic Device 以微流控装置内皮-血管周串扰为中心的血管内重构分析

Journal of Robotics and Mechatronics Pub Date : 2023-10-20 DOI: 10.20965/jrm.2023.p1165

Ryosuke Murai, Masafumi Watanabe, Ryo Sudo

{"title":"Analysis of Inward Vascular Remodeling Focusing on Endothelial–Perivascular Crosstalk in a Microfluidic Device","authors":"Ryosuke Murai, Masafumi Watanabe, Ryo Sudo","doi":"10.20965/jrm.2023.p1165","DOIUrl":"https://doi.org/10.20965/jrm.2023.p1165","url":null,"abstract":"Vascular remodeling is a crucial process for the effective delivery of oxygen and nutrients to the entire body during vascular formation. However, detailed mechanisms underlying vascular remodeling are not yet fully understood owing to the absence of an appropriate experimental model. To address this, in this study, we utilized a microfluidic vascular model with perivascular cells to investigate the mechanism of vascular remodeling by culturing human umbilical vein endothelial cells (HUVECs) and mesenchymal stem cells (MSCs) in a microfluidic device. We compared two different cell culture conditions: culturing HUVECs and MSCs (1) separately in different channels and (2) in the same channel. In both conditions, microvascular networks covered with perivascular cells were formed. Interestingly, a significant inward vascular remodeling occurred over time when HUVECs and MSCs were cultured in different channels. This remodeling was mediated by direct endothelial–perivascular crosstalk through α 6 integrin. Furthermore, computational fluid analysis revealed that hypothetical shear stress on the luminal surface of microvessels was attenuated during inward vascular remodeling, suggesting that the remodeling might be an adaptive change. Our findings and the microfluidic model will be useful not only for further elucidation of mechanisms underlying physiological and pathological vascular remodeling but also for constructing functional vascularized tissues and organs by controlling vascular remodeling.","PeriodicalId":51661,"journal":{"name":"Journal of Robotics and Mechatronics","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135568008","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Training Simulator for Manual Lathe Operation Using Motion Capture – Addition of Teaching Function and Evaluation of Training Effectiveness – 基于动作捕捉的手动车床操作训练模拟器。教学功能的增加与训练效果的评估

Journal of Robotics and Mechatronics Pub Date : 2023-02-20 DOI: 10.20965/jrm.2023.p0145

Nobuyoshi Hashimoto

{"title":"Training Simulator for Manual Lathe Operation Using Motion Capture – Addition of Teaching Function and Evaluation of Training Effectiveness –","authors":"Nobuyoshi Hashimoto","doi":"10.20965/jrm.2023.p0145","DOIUrl":"https://doi.org/10.20965/jrm.2023.p0145","url":null,"abstract":"Numerous training simulators have been developed using virtual reality (VR) owing to their various advantages. Systems for training machine operations with physical movements face differences in the operational feel between actual and virtual machines. Moreover, virtual training is problematic in safety education because trainees in safe virtual environments can exhibit unsafe behavior in reality. To solve these problems, a previous study developed a virtual reality (VR) system to train a lathe operation with mixed reality using a motion capture system. This study included a function to teach the procedure and safety precautions for straight turning operations using a lathe. To evaluate the training effectiveness of this system, an experiment was conducted to compare learning using a video. Testees were divided into a simulator group, who learned with the system, and a video group, who learned with the video material. Work on the actual lathe by each testee after learning, was evaluated. Consequently, the actual work by the testees who used this system had fewer errors and shorter standstill times in which they attempted to recollect the next phase task. Although the number of trainees was small, this relationship had a statistical advantage. In the actual work, all the testees in the video group entered the danger area; however, only half of the testees in the simulator group entered the danger area. Therefore, a trainee using a simulator can remember the work process more reliably and accurately and perform it safely. Moreover, trainees who have undergone training several times should be able to perform actual work without making operational errors or engaging in unsafe behaviors.","PeriodicalId":51661,"journal":{"name":"Journal of Robotics and Mechatronics","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134904443","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Congratulations! Journal of Robotics and Mechatronics Best Paper Award 2022 恭喜你!机器人与机电一体化杂志最佳论文奖2022

Journal of Robotics and Mechatronics Pub Date : 2023-02-20 DOI: 10.20965/jrm.2023.p0001

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A Multi-Criteria Optimization Approach to Cam Curve Design Combining Different Splines Given by Fixed and Adjustable Checkpoints 固定和可调检查点给出不同样条的凸轮曲线多准则优化设计方法

IF 1.1

Journal of Robotics and Mechatronics Pub Date : 2023-01-01 DOI: 10.3844/jmrsp.2023.15.26

Léo Moussafir, V. Arakelian

引用次数: 0