Journal of Obstetrics and Gynecology of India最新文献

{"title":"Prenatal Attachment Inventory: Adaptation and Validation in the Indian Context.","authors":"K Rajitha, Manish Kumar Verma, V Anand Mohan","doi":"10.1007/s13224-025-02210-9","DOIUrl":"10.1007/s13224-025-02210-9","url":null,"abstract":"<p><strong>Background: </strong>This study aimed to translate and validate the Prenatal Attachment Inventory (PAI) into Malayalam to address a gap in Maternal-Fetal Attachment (MFA) research in India. The PAI was adapted based on John Bowlby's attachment theory and Mecca Cranley's Maternal-Fetal Attachment Scale (MFAS), incorporating expert feedback to reflect Indian cultural contexts better.</p><p><strong>Methods: </strong>The translated PAI was administered to 250 pregnant women in Kerala. The translation process included adding three new items focused on maternal self-care, activities with the fetus, and resource usage, categorized as \"personal reflection.\" These additions, alongside original factors of anticipation, differentiation, and interaction, were validated by reviewers, resulting in a Content Validity Ratio of 0.95.</p><p><strong>Results: </strong>Initial Confirmatory Factor Analysis indicated a Comparative Fit Index (CFI) of 0.821, Tucker-Lewis Index (TLI) of 0.791, Standardized Root Mean Square Residual (SRMR) of 0.0631, and Root Mean Square Error of Approximation (RMSEA) of 0.0764. After removing four low-loading items, the revised model showed improved fit indices: CFI of 0.843, TLI of 0.811, SRMR of 0.0591, and RMSEA of 0.0802, with Akaike Information Criterion and Bayesian Information Criterion values decreasing to 9823 and 10,024.</p><p><strong>Conclusion: </strong>The Cronbach's alpha of 0.868 for the Malayalam PAI demonstrated strong internal consistency. This validated tool provides a reliable and culturally appropriate measure for MFA in India, supporting future research and interventions to enhance maternal and fetal health outcomes.</p>","PeriodicalId":51563,"journal":{"name":"Journal of Obstetrics and Gynecology of India","volume":"76 3","pages":"226-232"},"PeriodicalIF":0.5,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13294429/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148347295","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Does Hypoglycemia During 50-g Glucose Challenge Test Adversely Affect Perinatal Outcomes?","authors":"Yıldız Akdas Reis, Alperen Aksan, Fahri Burcin Firatligil, Arife Akay, Rahmi Sinan Karadeniz, Yaprak Ustun","doi":"10.1007/s13224-025-02236-z","DOIUrl":"10.1007/s13224-025-02236-z","url":null,"abstract":"<p><strong>Background/purpose: </strong>This study aims to assess maternal and neonatal outcomes in pregnancies complicated by hypoglycemia during the 50-g oral glucose challenge test (GCT).</p><p><strong>Methods: </strong>This is a retrospective cohort analysis of all live births at a single medical center between 2015 and 2019 with available 50-g GCT results and birth outcomes. Hypoglycemia during 50-g GCT was defined as a glucose value below 88 mg/dl at the first-hour glucose result. Maternal characteristics and perinatal outcomes were compared between two groups: hypoglycemia at 50-g GCT (group 1) and normal 50-g GCT (group 2).</p><p><strong>Results: </strong>A total of 535 nulliparous cases were included. No significant differences were observed in delivery week and day, Apgar scores at 1 and 5 min, mode of delivery, fetal sex, and admission to the neonatal intensive care unit (<i>p</i> > 0.05). While no significant differences were found in prenatal biparietal diameter, abdominal circumference, and femur length (<i>p</i> value, 0.486, 0.297, and 0.106, respectively), birth weight was significantly lower in the hypoglycemic group (3222 ± 566 vs. 3340 ± 410, <i>p</i> < 0.001).</p><p><strong>Conclusion: </strong>Hypoglycemia during a 50-g GCT is significantly associated with lower birth weight. Pregnant women experiencing hypoglycemia during the 50-g GCT at 24-28 weeks' gestation should be closely monitored, possibly classified as high-risk pregnancies, considering the potential for unfavorable perinatal outcomes.</p>","PeriodicalId":51563,"journal":{"name":"Journal of Obstetrics and Gynecology of India","volume":"76 3","pages":"242-247"},"PeriodicalIF":0.5,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13294393/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148347061","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of Hypothyroidism on Ovarian Reserve in Infertile Reproductive-Aged Women: A Cross-Sectional Study.","authors":"Bardia Amidi, Narges Naderi, Masoumeh Ghafarzadeh, Arian Abasinezhad, Fatemeh Yari, Mojgan Kaviani Charati","doi":"10.1007/s13224-025-02147-z","DOIUrl":"10.1007/s13224-025-02147-z","url":null,"abstract":"<p><strong>Purpose: </strong>The purpose of the study is to evaluate the effects of thyroid function on ovarian reserve in reproductive-aged women attending Barkat Infertility Center and Shahid Rahimi Medical Center, Khorramabad, Lorestan, Iran.</p><p><strong>Methods/subjects: </strong>Descriptive-analytical cross-sectional research was conducted on 318 infertile women of reproductive age from July 2023 to March 2024. Subjects were selected through random sampling, and the inclusion criteria required infertility for more than a year without any anatomical, genetic, or systemic causes. A history of prior ovarian surgery, chemotherapy, radiotherapy, thyroid diseases, polycystic ovary syndrome, and hyperprolactinemia were all exclusion criteria. Data on demographic and clinical data were gathered, and blood samples were tested for thyroid function (TSH, FT4) and ovarian reserve markers (AMH, estradiol, and FSH).</p><p><strong>Results: </strong>Among the participants, clinical hypothyroidism and subclinical hypothyroidism were found in 10.4 and 3.8% of cases. A significant relationship was identified between TSH and AMH levels. Increased TSH levels and higher FT4 levels were both significantly associated with decreased ovarian reserve, as indicated by AMH < 1.1 ng/mL. Additionally, there were negative correlations for age and BMI with ovarian reserve and positive correlations for estradiol.</p><p><strong>Conclusion: </strong>This study concluded that, among infertile women, a significant inverse relationship between thyroid function and ovarian reserve does exist. Higher TSH and FT4 levels were both associated with low levels of AMH; hence, thyroid dysfunction may impair ovarian function. These findings emphasize how imperative complete thyroid investigations are in infertility investigations. Further research is needed to establish the cause and offer specific treatments regarding thyroid disorders and infertility.</p>","PeriodicalId":51563,"journal":{"name":"Journal of Obstetrics and Gynecology of India","volume":"76 3","pages":"206-212"},"PeriodicalIF":0.5,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13294390/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148347166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"From Continence to Incontinence: Challenges and Advances in Care.","authors":"Sujata Dalvi","doi":"10.1007/s13224-026-02421-8","DOIUrl":"10.1007/s13224-026-02421-8","url":null,"abstract":"<p><p>Urinary incontinence (UI), defined as involuntary leakage of urine, is a common condition in women, particularly after 50 years of age. Despite its recognition as a disease by the International Classification of Diseases, UI remains underreported due to stigma and misconceptions, with a significant impact on quality of life, mental health, and social functioning. This review outlines the classification of UI (stress, urge, mixed, overflow, functional), underlying pathophysiology, and contributory factors such as ageing, trauma, surgery, and menopause. Evaluation includes detailed history, physical examination, urological tests, and urodynamic studies to differentiate causes and guide management. Management strategies range from lifestyle modification, pelvic floor muscle therapy, bladder training, and medical interventions (antimuscarinics, β3 adrenergic agonists, vaginal oestrogens) to surgical procedures including mid-urethral slings, urethropexy, periurethral injectables, and artificial sphincters. Emerging therapies such as neuromodulation, onabotulinumtoxin A injections, and electromagnetic devices (Emsella chairs) show promise. UI is strongly associated with depression, sexual dysfunction, poor sleep, and reduced productivity. UI is a multifactorial condition requiring patient-centred, multidisciplinary care. Advances in bladder physiology research, genetic studies, and novel therapies targeting bladder microbiota highlight future directions. Early detection, prevention, and improved patient-reported outcomes remain central to enhancing quality of life in affected women.</p>","PeriodicalId":51563,"journal":{"name":"Journal of Obstetrics and Gynecology of India","volume":"76 3","pages":"185-191"},"PeriodicalIF":0.5,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13294417/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148347163","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Proteinuric and Non-proteinuric Pre-eclampsia: A Comparative Analysis of Risk Factor Profile, Clinical Picture, Laboratory Parameters and Pregnancy Outcome.","authors":"Yalamanchali Sree Bhavya, Pramila Jena, Sirisha Voola, Bandita Panda, G Prasanna, Jyochnamayi Panda","doi":"10.1007/s13224-025-02223-4","DOIUrl":"10.1007/s13224-025-02223-4","url":null,"abstract":"<p><strong>Background: </strong>Pre-eclampsia, a hypertensive disorder of pregnancy remains a challenge worldwide despite advance in the medical science and research due to its adverse impact on pregnancy.</p><p><strong>Objectives: </strong>To compare the clinical characteristics, sociodemographic risk factors and the pregnancy outcomes between proteinuric and non-proteinuric pre-eclampsia incorporating the revised definition.</p><p><strong>Methodology: </strong>A prospective observational study consisting of 147 case of pre-eclampsia as per ISSHP-2018 diagnostic criteria of which 91 (63.6%) with proteinuria and 52 (36.4%) were without proteinuria. The maternal characteristics and pregnancy outcome were studied in both the groups and analyzed using appropriate statistical method.</p><p><strong>Results: </strong>Use of revised definition lead to 1.5% increase in the incidence of pre-eclampsia (PE). A significantly higher proportion of non-proteinuric PE were ≤ 30 years as compared to proteinuric PE (78.8% vs. 61.5%, <i>p</i> value: 0.033). The proteinuric PE had significantly higher mean systolic and mean arterial pressure (<i>p</i> value: 0.011), higher association with clinically severe disease (<i>p</i> value: 0.008), higher values of serum creatinine (<i>p</i> value: 0.024) and serum LDH levels (<i>p</i> value: 0.004), higher rate of growth retarded fetus (<i>p</i> value: 0.029), low birth weight (<i>p</i> value: 0.014) and peri-natal mortality (<i>p</i> value: 0.018) as compared to non-proteinuric PE. However, the binary logistic regression analysis failed to demonstrate any significant difference between the two groups in any of the maternal characteristics or pregnancy outcome measures.</p><p><strong>Conclusion: </strong>PE with or without proteinuria can be equally severe compromising the pregnancy outcome and hence demands for increase supervision and monitoring once diagnosis of PE is established.</p>","PeriodicalId":51563,"journal":{"name":"Journal of Obstetrics and Gynecology of India","volume":"76 3","pages":"233-241"},"PeriodicalIF":0.5,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13294405/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148347274","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Conservative Approach to Uterovaginal Prolapse: Assessing the Effectiveness and Outcomes of Abdominal Sacrohysteropexy.","authors":"Taiba I Patel, Mahesh S Tandale, Swati Nagapurkar, Subohi Nishat","doi":"10.1007/s13224-025-02151-3","DOIUrl":"10.1007/s13224-025-02151-3","url":null,"abstract":"<p><strong>Background: </strong>Pelvic organ prolapse (POP) is the descent of the pelvic organs including bladder, rectum, uterus, vaginal vault and intestines, beyond their anatomical confines.The goal of uterine conserving surgical alternatives is to improve quality of life and reduce symptoms by restoring anatomy and function.</p><p><strong>Purpose: </strong>This study assesses the effectiveness of sacrohysteropexy by evaluation of intra-operative and post-operative complications and recurrence rates.</p><p><strong>Methods: </strong>This study involved 18 women under 45 with stage 2 to stage 4 prolapse who underwent abdominal sacrohysteropexy at a tertiary care hospital. A comprehensive evaluation assessed surgical duration, complications, blood transfusion needs, and hospital stay length both pre- and post-surgery. Patients were monitored for 12 months after discharge to track recovery and any long-term effects or recurrence of prolapse.</p><p><strong>Results: </strong>Age distribution: 7 aged 21-30, 10 patients aged 31-40, 1 over 40.All patients were married. Parity: 1 was nulliparous, 13 patients had 1-3 children and 4 had 4-6 children. Prolapse stage : 2 patients each had stage 2 and stage 4 had whereas 14 patients had stage 3 while.Blood loss: 1 case required transfusion (500 ml). Mean Surgery duration: 60-90 mins on. Complications: 1 case of wound dehiscence. Discharge: Average duration of hospital stays was 5-7 days. Follow-up: Mean 12 months. no mesh erosion or recurrence detected. Deep dyspareunia: Reported in 1 patient during follow-up. Success rate: (100%).</p><p><strong>Conclusion: </strong>Abdominal Sacrohysteropexy is a safe and effective treatment option for women suffering from uterovaginal prolapse with willingness to preserve the menstrual and reproductive functions.</p>","PeriodicalId":51563,"journal":{"name":"Journal of Obstetrics and Gynecology of India","volume":"76 3","pages":"213-217"},"PeriodicalIF":0.5,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13294422/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148347339","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Artificial Intelligence Colposcopy Models for Cervical Cancer Screening and Diagnosis: A Systematic Review and Meta-Analysis.","authors":"Swati Priya, Sunil Kumar Panigrahi, Vikash Bansal, Amiy Arnav, Manish Raj, Priyanka Rai","doi":"10.1007/s13224-026-02352-4","DOIUrl":"10.1007/s13224-026-02352-4","url":null,"abstract":"<p><strong>Background: </strong>Cervical cancer is a significant public health problem globally, with limited access to screening and diagnostic resources in developing countries contributing to its high burden. Artificial Intelligence (AI) has emerged as a promising tool to enhance the diagnostic performance of colposcopy, a procedure used to visually examine the cervix for abnormal cell growth. The findings of this study will contribute to the growing body of evidence on the role of Artificial Intelligence (AI) in cervical cancer diagnosis.</p><p><strong>Materials and methods: </strong>This Meta-analysis aims to synthesize data and provide a comprehensive evaluation of the diagnostic performance of AI-assisted colposcopy systems (sensitivity, specificity, and accuracy) for Cervical malignancy and premalignant lesions.A comprehensive literature search was conducted across multiple databases, and 12 studies were included in the Meta-analysis. Pooled estimates of sensitivity, specificity, and accuracy were calculated using a random-effects model, and heterogeneity statistics were computed to evaluate consistency across studies.</p><p><strong>Results: </strong>The pooled estimates of diagnostic performance were sensitivity, 78.1% (95% CI 71.4-84.0%); specificity, 80.6% (95% CI 74.2-85.8%); and accuracy, 83.1% (95% CI 77.8-88.2%). Subgroup analysis and heterogeneity testing were performed to explore sources of variability.</p><p><strong>Conclusion: </strong>The results suggest that AI-assisted colposcopy systems demonstrate promising diagnostic performance in Cervical malignancy and premalignant lesions diagnosis. However, substantial heterogeneity underscores the need for methodological standardization and reporting transparency in AI-based diagnostic research. Future research should focus on developing and validating AI models in diverse populations, evaluating clinical utility and cost-effectiveness, and investigating the impact of AI-assisted colposcopy on patient outcomes and healthcare systems.</p><p><strong>Supplementary information: </strong>The online version contains supplementary material available at 10.1007/s13224-026-02352-4.</p>","PeriodicalId":51563,"journal":{"name":"Journal of Obstetrics and Gynecology of India","volume":"76 3","pages":"192-199"},"PeriodicalIF":0.5,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13294394/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148347337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"New-born Screening for Mitochondrial Disorders is Useful for Genetic Counseling and Early Treatment when Available.","authors":"Josef Finsterer","doi":"10.1007/s13224-024-02075-4","DOIUrl":"10.1007/s13224-024-02075-4","url":null,"abstract":"","PeriodicalId":51563,"journal":{"name":"Journal of Obstetrics and Gynecology of India","volume":"76 3","pages":"276-277"},"PeriodicalIF":0.5,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13294397/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148347201","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Comparative Analysis of Fertility-Sparing Surgery and Complete Staging Surgery in Early Stage Epithelial Ovarian Cancer: Impact on Oncological Outcomes.","authors":"Priyaroseni Briskala, Vinotha Thomas, Ajit Sebastian, Reka Karuppusami, Dhanya Susan Thomas, Ashish Singh, Sherin Daniel, Rachel Chandy, Anitha Thomas","doi":"10.1007/s13224-025-02239-w","DOIUrl":"10.1007/s13224-025-02239-w","url":null,"abstract":"<p><strong>Background: </strong>Fertility-sparing surgery (FS) is a viable option for women with early-stage epithelial ovarian cancer (EOC) desiring fertility preservation. However, its oncological outcomes remain debated.</p><p><strong>Methods: </strong>This retrospective cohort study analysed 135 patients with FIGO (International Federation of Gynaecology and Obstetrics) stage I EOC, operated between 1st January 2011 and 31st December 2020, comparing clinicopathological characteristics and oncologic outcomes between women who underwent FS (<i>n</i> = 26) and comprehensive staging surgery (CS) (<i>n</i> = 109). Continuous variables were compared using a <i>t</i>-test and Mann-Whitney test, while categorical variables were compared using the Chi-Square test. Disease-free and overall survival were plotted using Kaplan-Meier curves and compared using a log-rank test.</p><p><strong>Results: </strong>During this period, Stage I EOC constituted 13.9% of the patients with EOC who underwent surgery. Patients in the FS group were younger (mean age 28.6 years versus 43 years, <i>p</i> = 0.00), with higher rates of nulliparity (77% versus 15%, <i>p</i> = 0.00). Though the pathological profile of the tumours in both groups was similar, 12(46%) in the FS group had high-grade histology. The FS group had a poorer follow-up rate (70% versus 83%, <i>p</i> = 0.033), a higher recurrence rate (30% vs. 8%, <i>p</i> = 0.001), and shorter mean disease-free survival (84.78 months vs. 124.86 months, <i>p</i> = 0.002). Older age and FS were significant predictors of recurrence at 2 and 5 years.</p><p><strong>Conclusion: </strong>This study suggests that FS may be associated with higher recurrence rates in early-stage EOC. Careful patient selection, precise surgical information, and thorough follow-up protocols are crucial to balancing oncological safety with reproductive goals.</p><p><strong>Supplementary information: </strong>The online version contains supplementary material available at 10.1007/s13224-025-02239-w.</p>","PeriodicalId":51563,"journal":{"name":"Journal of Obstetrics and Gynecology of India","volume":"76 3","pages":"218-225"},"PeriodicalIF":0.5,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13294406/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148347320","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Randomized Controlled Trial to Compare Vaginal Dinoprostone Pessary with Intracervical Dinoprostone Gel for Pre-induction Cervical Ripening.","authors":"Mamta Kumari Chaudhary, Vanita Suri, Rashmi Bagga, Aashima Arora, Jogender Kumar, Vanita Jain","doi":"10.1007/s13224-025-02222-5","DOIUrl":"10.1007/s13224-025-02222-5","url":null,"abstract":"<p><strong>Purpose: </strong>To compare safety and efficacy of vaginal dinoprostone pessary with intracervical dinoprostone gel for cervical ripening at term.</p><p><strong>Methods: </strong>A hundred women with singleton pregnancies requiring labor induction with a Bishop score of ≤ 6 with intact membranes and no previous Cesarean Section (CS) were randomized to the pessary or gel group. All patients underwent assessment at baseline and every 8 h thereafter, along with the grading of discomfort noted on the visual analog scale (VAS). Pessary was kept for a maximum of 24 h, and the gel was inserted 8 hourly (maximum 3 doses).</p><p><strong>Results: </strong>The pessary group needed fewer assessments during the induction process (2.24 ± 0.82 vs. 2.58 ± 0.61, <i>p</i> = 0.004^**). The change in Bishop's score after 8 h was significantly higher in the pessary group (2.69 ± 1.42 vs. 1.81 ± 1.26, <i>p</i> = 0.006^**). The pessary group had a considerably better VAS score 2.54 ± 1.13 vs. 3.18 ± 1.24, <i>p</i> = 0.004^**), depicting better tolerance of pessary. There was no statistically significant difference between both groups in terms of induction to delivery interval (IDI), mode of delivery, duration of 1st, 2nd, and 3rd stage of labor, type of rupture of membrane, need for intervention, and the indication for intervention. The rate of CS was higher in the gel group, though the difference was not statistically significant. The neonatal outcomes showed no difference.</p><p><strong>Conclusion: </strong>Dinoprostone vaginal pessary is faster and better tolerated than cervical gel for cervical ripening at term. The IDI, mode of delivery, and maternal and neonatal outcomes were similar in pessary versus gel groups.</p>","PeriodicalId":51563,"journal":{"name":"Journal of Obstetrics and Gynecology of India","volume":"76 3","pages":"248-257"},"PeriodicalIF":0.5,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13294396/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148347352","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}