Liang Chen , Ke-Xing Jin , Jing Yang , Jun-Jie Ouyang , Han-Gang Chen , Si-Ru Zhou , Xiao-Qing Luo , Mi Liu , Liang Kuang , Yang-Li Xie , Yan Hu , Lin Chen , Zhen-Hong Ni , Xiao-Lan Du
{"title":"Total body water percentage and 3rd space water are novel risk factors for training-related lower extremity muscle injuries in young males","authors":"Liang Chen , Ke-Xing Jin , Jing Yang , Jun-Jie Ouyang , Han-Gang Chen , Si-Ru Zhou , Xiao-Qing Luo , Mi Liu , Liang Kuang , Yang-Li Xie , Yan Hu , Lin Chen , Zhen-Hong Ni , Xiao-Lan Du","doi":"10.1016/j.cjtee.2024.01.001","DOIUrl":"10.1016/j.cjtee.2024.01.001","url":null,"abstract":"<div><h3>Purpose</h3><p>To identify the risk factors for training-related lower extremity muscle injuries in young males by a non-invasive method of body composition analysis.</p></div><div><h3>Methods</h3><p>A total of 282 healthy young male volunteers aged 18 – 20 years participated in this cohort study. Injury location, degree, and injury rate were adjusted by a questionnaire based on the overuse injury assessment methods used in epidemiological studies of sports injuries. The occurrence of training injuries is monitored and diagnosed by physicians and treated accordingly. The body composition was measured using the BodyStat QuadScan 4000 multifrequency Bio-impedance system at 5, 50, 100 and 200 kHz to obtain 4 impedance values. The Shapiro-Wilk test was used to check whether the data conformed to a normal distribution. Data of normal distribution were shown as mean ± SD and analyzed by <em>t</em>-test, while those of non-normal distribution were shown as median (Q<sub>1</sub>, Q<sub>3</sub>) and analyzed by Wilcoxon rank sum test. The receiver operator characteristic curve and logistic regression analysis were performed to investigate risk factors for developing training-related lower extremity injuries and accuracy.</p></div><div><h3>Results</h3><p>Among the 282 subjects, 78 (27.7%) developed training injuries. Lower extremity training injuries revealed the highest incidence, accounting for 23.4% (66 cases). These patients showed higher percentages of lean body mass (<em>p</em> = 0.001), total body water (TBW, <em>p</em> = 0.006), extracellular water (<em>p</em> = 0.020) and intracellular water (<em>p</em> = 0.010) as well as a larger ratio of basal metabolic rate/total weight (<em>p</em> = 0.006), compared with those without lower extremity muscle injuries. On the contrary, the percentage of body fat (<em>p</em> = 0.001) and body fat mass index (<em>p =</em> 0.002) were lower. Logistic regression analysis showed that TBW percentage > 65.35% (<em>p</em> = 0.050, odds ratio = 3.114) and 3rd space water > 0.95% (<em>p</em> = 0.045, odds ratio = 2.342) were independent risk factors for lower extremity muscle injuries.</p></div><div><h3>Conclusion</h3><p>TBW percentage and 3rd space water measured with bio-impedance method are potential risk factors for predicting the incidence of lower extremity muscle injuries in young males following training.</p></div>","PeriodicalId":51555,"journal":{"name":"Chinese Journal of Traumatology","volume":"27 3","pages":"Pages 168-172"},"PeriodicalIF":2.1,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1008127524000014/pdfft?md5=e326fef6600fdc8e559c14f5db650e50&pid=1-s2.0-S1008127524000014-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139392070","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Risk factors and predictive model of cerebral edema after road traffic accidents-related traumatic brain injury","authors":"Di-You Chen , Peng-Fei Wu , Xi-Yan Zhu , Wen-Bing Zhao , Shi-Feng Shao , Jing-Ru Xie , Dan-Feng Yuan , Liang Zhang , Kui Li , Shu-Nan Wang , Hui Zhao","doi":"10.1016/j.cjtee.2024.02.001","DOIUrl":"10.1016/j.cjtee.2024.02.001","url":null,"abstract":"<div><h3>Purpose</h3><p>Cerebral edema (CE) is the main secondary injury following traumatic brain injury (TBI) caused by road traffic accidents (RTAs). It is challenging to be predicted timely. In this study, we aimed to develop a prediction model for CE by identifying its risk factors and comparing the timing of edema occurrence in TBI patients with varying levels of injuries.</p></div><div><h3>Methods</h3><p>This case-control study included 218 patients with TBI caused by RTAs. The cohort was divided into CE and non-CE groups, according to CT results within 7 days. Demographic data, imaging data, and clinical data were collected and analyzed. Quantitative variables that follow normal distribution were presented as mean ± standard deviation, those that do not follow normal distribution were presented as median (Q<sub>1</sub>, Q<sub>3</sub>). Categorical variables were expressed as percentages. The Chi-square test and logistic regression analysis were used to identify risk factors for CE. Logistic curve fitting was performed to predict the time to secondary CE in TBI patients with different levels of injuries. The efficacy of the model was evaluated using the receiver operator characteristic curve.</p></div><div><h3>Results</h3><p>According to the study, almost half (47.3%) of the patients were found to have CE. The risk factors associated with CE were bilateral frontal lobe contusion, unilateral frontal lobe contusion, cerebral contusion, subarachnoid hemorrhage, and abbreviated injury scale (AIS). The odds ratio values for these factors were 7.27 (95% confidence interval (<em>CI</em>): 2.08 − 25.42, <em>p</em> = 0.002), 2.85 (95% <em>CI</em>: 1.11 − 7.31, <em>p</em> = 0.030), 2.62 (95% <em>CI</em>: 1.12 − 6.13, <em>p</em> = 0.027), 2.44 (95% <em>CI</em>: 1.25 − 4.76, <em>p</em> = 0.009), and 1.5 (95% <em>CI</em>: 1.10 − 2.04, <em>p</em> = 0.009), respectively. We also observed that patients with mild/moderate TBI (AIS ≤ 3) had a 50% probability of developing CE 19.7 h after injury (χ<sup>2</sup> = 13.82, adjusted <em>R</em><sup>2</sup> = 0.51), while patients with severe TBI (AIS > 3) developed CE after 12.5 h (χ<sup>2</sup> = 18.48, adjusted <em>R</em><sup>2</sup> = 0.54). Finally, we conducted a receiver operator characteristic curve analysis of CE time, which showed an area under the curve of 0.744 and 0.672 for severe and mild/moderate TBI, respectively.</p></div><div><h3>Conclusion</h3><p>Our study found that the onset of CE in individuals with TBI resulting from RTAs was correlated with the severity of the injury. Specifically, those with more severe injuries experienced an earlier onset of CE. These findings suggest that there is a critical time window for clinical intervention in cases of CE secondary to TBI.</p></div>","PeriodicalId":51555,"journal":{"name":"Chinese Journal of Traumatology","volume":"27 3","pages":"Pages 153-162"},"PeriodicalIF":2.1,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1008127524000075/pdfft?md5=6e65c502c8deae3029ed272d27adb53e&pid=1-s2.0-S1008127524000075-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140066247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ming-Fu Fu, Hai-Ning Zuo, Tao Sun, Ming-Zhang Mu, Zhi-Yong Zhou
{"title":"Irreducible anteromedial radial head dislocation without fracture caused by transposed biceps tendon in an adult: A case report and literature review","authors":"Ming-Fu Fu, Hai-Ning Zuo, Tao Sun, Ming-Zhang Mu, Zhi-Yong Zhou","doi":"10.1016/j.cjtee.2023.05.004","DOIUrl":"10.1016/j.cjtee.2023.05.004","url":null,"abstract":"<div><p>Irreducible anteromedial radial head dislocation (IARHD) caused by transposed biceps tendon is rare. Delayed diagnosis and surgical failure often occur. A 46-year-old fisherman presented with 10 days history of painful swelling and restricted movement of his right elbow due to strangulation injury by a fishing boat cable. On examination, the images of the right elbow reveals in a \"semi-extended and pronated\" elastic fixation position. Radiography and 3-dimensional reconstruction CT reveals an isolated anteromedial radial head dislocation with extreme protonation of the radius and the bicipital tuberosity towards the posterior aspect of the elbow joint, and MRI shows biceps tendon wrapping around the radial neck, similar to umbilical cord wrapping seen in newborns. The Henry approach was applied for the first time to reduce the biceps tendon. The patient achieved a good functional recovery at 26 months, which represents the first reported case of IARHD without fracture caused by biceps tendon in an adult. In treatment of IARHD, attention should be paid to the phenomenon of biceps tendon transposition. Careful clinical examination, comprehensive imaging modalities, and appropriate surgical approach are the keys to successful management.</p></div>","PeriodicalId":51555,"journal":{"name":"Chinese Journal of Traumatology","volume":"27 3","pages":"Pages 180-186"},"PeriodicalIF":2.1,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1008127523000469/pdfft?md5=ccfba802e88732a6e5e90e330e6ad3d0&pid=1-s2.0-S1008127523000469-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9727214","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hao Liu , Jun Liu , Yong-Wei Wu , Ming Zhou , Yong-Jun Rui
{"title":"Clinical efficacy of the topical application of tranexamic acid in tendon release in the hand: A randomized controlled trial","authors":"Hao Liu , Jun Liu , Yong-Wei Wu , Ming Zhou , Yong-Jun Rui","doi":"10.1016/j.cjtee.2023.12.001","DOIUrl":"10.1016/j.cjtee.2023.12.001","url":null,"abstract":"<div><h3>Purpose</h3><p>To study the clinical effectiveness of the topical application of tranexamic acid in hand tendon release.</p></div><div><h3>Methods</h3><p>This was a randomized controlled trial conducted after receiving approval from the local ethics committee according to guidelines from the Helsinki Declaration. Eighty patients who underwent hand tendon release operation in our hospital from January 2021 to December 2022 were included and randomly divided into 2 groups. Patients in the tranexamic acid group (40 cases) received intraoperative topical application of 2 g of tranexamic acid after tendon release, while patients in the conventional group (40 cases) did not receive topical application of tranexamic acid during operation. The operation time, perioperative hemoglobin changes, total blood loss, incidence of early postoperative complications, and total active movement (TAM) before surgery and 6 months after surgery were compared between the 2 groups. The continuous variable which follows normal distribution expressed by mean ± SD and used <em>t</em>-test to compare between groups. Meanwhile, categorical variables were used by Chi-square test, and a <em>p</em> < 0.05 indicated that the differences were statistically significant.</p></div><div><h3>Results</h3><p>Both groups were followed up for 7 – 18 months, with a mean of 10.3 months. Postoperative decrease in hemoglobin was significantly less in the tranexamic acid group than in the conventional group (<em>t</em> = 7.611, <em>p</em> < 0.001). The total blood loss in the tranexamic acid group (74.33 ± 20.50) mL was less than that in the conventional group (83.05 ± 17.73) mL, and the difference was statistically significant (<em>p</em> < 0.05). Both groups showed improvement in thumb/finger flexion and extension range of motion after surgery, and the TAM improved compared with those before surgery, and the difference was statistically significant (<em>p</em> < 0.001). The TAM improved more significantly in the tranexamic acid group (87.68° ± 10.44°) than in the conventional group (80.47° ± 10.93°) at 6 months after surgery, with a statistically significant difference (<em>t</em> = 3.013, <em>p</em> < 0.001). There was no significant difference in operation time and incidence of early postoperative complications between the 2 groups (<em>p</em> = 0.798, 0.499, respectively).</p></div><div><h3>Conclusion</h3><p>The topical application of tranexamic acid during hand tendon release can significantly reduce postoperative bleeding and improve surgical efficacy, which is worth promoting.</p></div>","PeriodicalId":51555,"journal":{"name":"Chinese Journal of Traumatology","volume":"27 3","pages":"Pages 163-167"},"PeriodicalIF":2.1,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1008127523001414/pdfft?md5=b4284b7af4ce1121ad4aeb352e8971d4&pid=1-s2.0-S1008127523001414-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139432269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lin-Fei Cheng , Chao-Qun You , Cheng Peng , Jia-Ji Ren , Kai Guo , Tie-Long Liu
{"title":"Mesenchymal stem cell-derived exosomes as a new drug carrier for the treatment of spinal cord injury: A review","authors":"Lin-Fei Cheng , Chao-Qun You , Cheng Peng , Jia-Ji Ren , Kai Guo , Tie-Long Liu","doi":"10.1016/j.cjtee.2024.03.009","DOIUrl":"10.1016/j.cjtee.2024.03.009","url":null,"abstract":"<div><p>Spinal cord injury (SCI) is a devastating traumatic disease seriously impairing the quality of life in patients. Expectations to allow the hopeless central nervous system to repair itself after injury are unfeasible. Developing new approaches to regenerate the central nervous system is still the priority. Exosomes derived from mesenchymal stem cells (MSC-Exo) have been proven to robustly quench the inflammatory response or oxidative stress and curb neuronal apoptosis and autophagy following SCI, which are the key processes to rescue damaged spinal cord neurons and restore their functions. Nonetheless, MSC-Exo in SCI received scant attention. In this review, we reviewed our previous work and other studies to summarize the roles of MSC-Exo in SCI and its underlying mechanisms. Furthermore, we also focus on the application of exosomes as drug carrier in SCI. In particular, it combs the advantages of exosomes as a drug carrier for SCI, imaging advantages, drug types, loading methods, etc., which provides the latest progress for exosomes in the treatment of SCI, especially drug carrier.</p></div>","PeriodicalId":51555,"journal":{"name":"Chinese Journal of Traumatology","volume":"27 3","pages":"Pages 134-146"},"PeriodicalIF":2.1,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1008127524000361/pdfft?md5=a18243d18d371b9ad16948d9c79b0199&pid=1-s2.0-S1008127524000361-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140868097","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effectiveness and safety of augmentative plating technique in managing nonunion following intramedullary nailing of long bones in the lower extremity: A systematic review and meta-analysis.","authors":"Cong-Xiao Fu, Hao Gao, Jun Ren, Hu Wang, Shuai-Kun Lu, Guo-Liang Wang, Zhen-Feng Zhu, Yun-Yan Liu, Wen Luo, Yong Zhang, Yun-Fei Zhang","doi":"10.1016/j.cjtee.2024.04.004","DOIUrl":"https://doi.org/10.1016/j.cjtee.2024.04.004","url":null,"abstract":"<p><strong>Purpose: </strong>To methodically assess the effectiveness of augmentative plating (AP) and exchange nailing (EN) in managing nonunion following intramedullary nailing for long bone fractures of the lower extremity.</p><p><strong>Methods: </strong>PubMed, EMBASE, Web of Science, and the Cochrane Library were searched to gather clinical studies regarding the use of AP and EN techniques in the treatment of nonunion following intramedullary nailing of lower extremity long bones. The search was conducted up until May 2023. The original studies underwent an independent assessment of their quality, a process conducted utilizing the Newcastle-Ottawa scale. Data were retrieved from these studies, and meta-analysis was executed utilizing Review Manager 5.3.</p><p><strong>Results: </strong>This meta-analysis included 8 studies involving 661 participants, with 305 in the AP group and 356 in the EN group. The results of the meta-analysis demonstrated that the AP group exhibited a higher rate of union (odds ratio: 8.61, 95% confidence intervals (CI): 4.12 - 17.99, p < 0.001), shorter union time (standardized mean difference (SMD): -1.08, 95 % CI: -1.79 - -0.37, p = 0.003), reduced duration of the surgical procedure (SMD: -0.56, 95 % CI: -0.93 - -0.19, p = 0.003), less bleeding (SMD: -1.5, 95 % CI: -2.81 - -0.18), p = 0.03), and a lower incidence of complications (relative risk: -0.17, 95 % CI: -0.27 - -0.06, p = 0.001). In the subgroup analysis, the time for union in the AP group in nonisthmal and isthmal nonunion of lower extremity long bones was shorter compared to the EN group (nonisthmal SMD: -1.94, 95 % CI: -3.28 - -0.61, p < 0.001; isthmal SMD: -1.08, 95 % CI: -1.64 - -0.52, p = 0.002).</p><p><strong>Conclusion: </strong>In the treatment of nonunion in diaphyseal fractures of the long bones in the lower extremity, the AP approach is superior to EN, both intraoperatively (with reduced duration of the surgical procedure and diminished blood loss) and postoperatively (with an elevated union rate, shorter union time, and lower incidence of complications). Specifically, in the management of nonunion of lower extremity long bones with non-isthmal and isthmal intramedullary nails, AP demonstrated shorter union time in comparison to EN.</p>","PeriodicalId":51555,"journal":{"name":"Chinese Journal of Traumatology","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2024-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140960786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Intramedullary nailing for irreducible spiral subtrochanteric fractures: A comparison of cerclage and non-cerclage wiring","authors":"","doi":"10.1016/j.cjtee.2024.03.011","DOIUrl":"10.1016/j.cjtee.2024.03.011","url":null,"abstract":"<div><h3>Purpose</h3><p>Intramedullary nailing is the preferred internal fixation technique for the treatment of subtrochanteric fractures because of its biomechanical advantages. However, no definitive conclusion has been reached regarding whether combined cable cerclage is required during intramedullary nailing treatment. This study is performed to compare the clinical effects of intramedullary nailing with cerclage and non-cerclage wiring in the treatment of irreducible spiral subtrochanteric fractures.</p></div><div><h3>Methods</h3><p>Patients with subtrochanteric fractures admitted to our center from January 2013 to December 2021 were retrospectively analyzed. The patients were enrolled in the case-control study according to the inclusion and exclusion criteria and divided into the non-cerclage group and the cerclage group. The patients' clinical data, including the operative time, intraoperative blood loss, hospital stay, reoperation rate, fracture union time, and Harris hip score, were compared between these 2 groups. Categorical variables were compared using Chi-square or Fisher's exact test. Continuous variables with normal distribution were presented as mean ± standard deviation and analyzed with Student's <em>t</em>-test. Non-normally distributed variables were expressed as median (Q<sub>1</sub>, Q<sub>3</sub>) and assessed using the Mann-Whitney test. A <em>p</em> < 0.05 was considered significant.</p></div><div><h3>Results</h3><p>In total, 69 patients were included in the study (35 patients in the non-cerclage group and 34 patients in the cerclage group). The baseline data of the 2 groups were comparable. There were no significant difference in the length of hospital stay (z = -0.391, <em>p</em> = 0.696), operative time (z = -1.289, <em>p</em> = 0.197), or intraoperative blood loss (z = -1.321, <em>p</em> = 0.186). However, compared with non-cerclage group, the fracture union time was shorter (z = -5.587, <em>p</em> < 0.001), the rate of nonunion was lower (<em>χ</em><sup>2</sup> = 6.030, <em>p</em> = 0.03), the anatomical reduction rate was higher (<em>χ</em><sup>2</sup> = 5.449, <em>p</em> = 0.03), and the Harris hip score was higher (z = -2.99, <em>p</em> = 0.003) in the cerclage group, all with statistically significant differences.</p></div><div><h3>Conclusions</h3><p>Intramedullary nailing combined with cable cerclage wiring is a safe and reliable technique for the treatment of irreducible subtrochanteric fractures. This technique can improve the reduction effect, increase the stability of fracture fixation, shorten the fracture union time, reduce the occurrence of nonunion, and contribute to the recovery of hip joint function.</p></div>","PeriodicalId":51555,"journal":{"name":"Chinese Journal of Traumatology","volume":"27 5","pages":"Pages 305-310"},"PeriodicalIF":1.8,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1008127524000385/pdfft?md5=304525529b2a86d5f0f0ed5981e0319c&pid=1-s2.0-S1008127524000385-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140874912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Xiao-Fei Huang , Shuai-Feng Ma , Xu-Heng Jiang , Ren-Jie Song , Mo Li , Ji Zhang , Tian-Jing Sun , Quan Hu , Wen-Rui Wang , An-Yong Yu , He Li
{"title":"Causes and global, regional, and national burdens of traumatic brain injury from 1990 to 2019","authors":"Xiao-Fei Huang , Shuai-Feng Ma , Xu-Heng Jiang , Ren-Jie Song , Mo Li , Ji Zhang , Tian-Jing Sun , Quan Hu , Wen-Rui Wang , An-Yong Yu , He Li","doi":"10.1016/j.cjtee.2024.03.007","DOIUrl":"10.1016/j.cjtee.2024.03.007","url":null,"abstract":"<div><h3>Purpose</h3><div>Traumatic brain injury (TBI), currently a major global public health problem, imposes a significant economic burden on society and families. We aimed to quantify and predict the incidence and severity of TBI by analyzing its incidence, prevalence, and years lived with disability (YLDs). The epidemiological changes in TBI from 1990 to 2019 were described and updated to provide a reference for developing prevention, treatment, and incidence-reducing measures for TBI.</div></div><div><h3>Methods</h3><div>A secondary analysis was performed on the incidence, prevalence, and YLDs of TBI by sex, age group, and region (<em>n</em> = 21,204 countries and territories) between 1990 and 2019 using the Global Burden of Diseases, Injuries, and Risk Factors Study 2019. Proportions in the age-standardized incidence rate due to underlying causes of TBI and proportions of minor and moderate or severe TBI were also reported.</div></div><div><h3>Results</h3><div>In 2019, there were 27.16 million (95% uncertainty intervals (<em>UI</em>): 23.36 − 31.42) new cases of TBI worldwide, with age-standardized incidence and prevalence rates of 346 per 100,000 population (95% <em>UI</em>: 298 – 401) and 599 per 100,000 population (95% <em>UI</em>: 573 – 627), respectively. From 1990 to 2019, there were no significant trends in global age-standardized incidence (estimated annual percentage changes: -0.11%, 95% <em>UI</em>: -0.18% − -0.04%) or prevalence (estimated annual percentage changes: 0.01%, 95% <em>UI</em>: -0.04% − 0.06%). TBI caused 7.08 million (95% <em>UI</em>: 5.00 − 9.59) YLDs in 2019, with age-standardized rates of 86.5 per 100,000 population (95% <em>UI</em>: 61.1 − 117.2). In 2019, the countries with higher incidence rates were mainly distributed in Central Europe, Eastern Europe, and Australia. The 2019 global age-standardized incidence rate was higher in males than in females. The 2019 global incidence of moderate and severe TBI was 182.7 per 100,000 population, accounting for 52.8% of all TBI, with falls and road traffic injuries being the main causes in most regions.</div></div><div><h3>Conclusions</h3><div>The incidence of moderate and severe TBI was slightly higher in 2019, and TBI still accounts for a significant portion of the global injury burden. The likelihood of moderate to severe TBI and the trend of major injury under each injury cause from 1990 to 2019 and the characteristics of injury mechanisms in each age group are presented, providing a basis for further research on injury causes in each age group and the future establishment of corresponding policies and protective measures.</div></div>","PeriodicalId":51555,"journal":{"name":"Chinese Journal of Traumatology","volume":"27 6","pages":"Pages 311-322"},"PeriodicalIF":1.8,"publicationDate":"2024-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140277115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Chao Zhang , Juan Li , Ping-Li Wang , Hua-Yun Chen , Yu-Hang Zhao , Ning Wang , Zhi-Tao Zhang , Yan-Wei Dang , Hong-Quan Wang , Jun Wang , Chu-Hua Fu
{"title":"Multimodal image fusion-assisted endoscopic evacuation of spontaneous intracerebral hemorrhage","authors":"Chao Zhang , Juan Li , Ping-Li Wang , Hua-Yun Chen , Yu-Hang Zhao , Ning Wang , Zhi-Tao Zhang , Yan-Wei Dang , Hong-Quan Wang , Jun Wang , Chu-Hua Fu","doi":"10.1016/j.cjtee.2024.03.006","DOIUrl":"10.1016/j.cjtee.2024.03.006","url":null,"abstract":"<div><h3>Purpose</h3><div>Although traditional craniotomy (TC) surgery has failed to show benefits for the functional outcome of intracerebral hemorrhage (ICH). However, a minimally invasive hematoma removal plan to avoid white matter fiber damage may be a safer and more feasible surgical approach, which may improve the prognosis of ICH. We conducted a historical cohort study on the use of multimodal image fusion-assisted neuroendoscopic surgery (MINS) for the treatment of ICH, and compared its safety and effectiveness with traditional methods.</div></div><div><h3>Methods</h3><div>This is a historical cohort study involving 241 patients with cerebral hemorrhage. Divided into MINS group and TC group based on surgical methods. Multimodal images (CT skull, CT angiography, and white matter fiber of MRI diffusion-tensor imaging) were fused into 3 dimensional images for preoperative planning and intraoperative guidance of endoscopic hematoma removal in the MINS group. Clinical features, operative efficiency, perioperative complications, and prognoses between 2 groups were compared. Normally distributed data were analyzed using <em>t</em>-test of 2 independent samples, Non-normally distributed data were compared using the Kruskal-Wallis test. Meanwhile categorical data were analyzed via the Chi-square test or Fisher’s exact test. All statistical tests were two-sided, and <em>p</em> < 0.05 was considered statistically significant.</div></div><div><h3>Results</h3><div>A total of 42 patients with ICH were enrolled, who underwent TC surgery or MINS. Patients who underwent MINS had shorter operative time (<em>p</em> < 0.001), less blood loss (<em>p</em> < 0.001), better hematoma evacuation (<em>p</em> = 0.003), and a shorter stay in the intensive care unit (<em>p</em> = 0.002) than patients who underwent TC. Based on clinical characteristics and analysis of perioperative complications, there is no significant difference between the 2 surgical methods. Modified Rankin scale scores at 180 days were better in the MINS than in the TC group (<em>p</em> = 0.014).</div></div><div><h3>Conclusions</h3><div>Compared with TC for the treatment of ICH, MINS is safer and more efficient in cleaning ICH, which improved the prognosis of the patients. In the future, a larger sample size clinical trial will be needed to evaluate its efficacy.</div></div>","PeriodicalId":51555,"journal":{"name":"Chinese Journal of Traumatology","volume":"27 6","pages":"Pages 340-347"},"PeriodicalIF":1.8,"publicationDate":"2024-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140282163","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A retrospective study of occlusal reconstruction in patients with old jaw fractures and dentition defects","authors":"","doi":"10.1016/j.cjtee.2024.03.004","DOIUrl":"10.1016/j.cjtee.2024.03.004","url":null,"abstract":"<div><h3>Purpose</h3><p>This study evaluated the methods and clinical effects of multidisciplinary collaborative treatment for occlusal reconstruction in patients with old jaw fractures and dentition defects.</p></div><div><h3>Methods</h3><p>Patients with old jaw fractures and dentition defects who underwent occlusal reconstruction at the Third Affiliated Hospital of Air Force Military Medical University from January 2018 to December 2022 were enrolled. Clinical treatment was classified into 3 phases. In phase I, techniques such as orthognathic surgery, microsurgery, and distraction osteogenesis were employed to reconstruct the correct 3-dimensional (3D) jaw position relationship. In phase II, bone augmentation and soft tissue management techniques were utilized to address insufficient alveolar bone mass and poor gingival soft tissue conditions. In phase III, implant-supported overdentures or fixed dentures were used for occlusal reconstruction. A summary of treatment methods, clinical efficacy evaluation, comparative analysis of imageological examinations, and satisfaction questionnaire survey were utilized to evaluate the therapeutic efficacy in patients with traumatic old jaw fractures and dentition defects. All data are summarized using the arithmetic mean ± standard deviation and compared using independent sample <em>t</em>-tests.</p></div><div><h3>Results</h3><p>In 15 patients with old jaw fractures and dentition defects (an average age of 32 years, ranging from 18 to 53 years), there were 7 cases of malocclusion of single maxillary fracture, 6 of malocclusion of single mandible fracture, and 2 of malocclusion of both maxillary and mandible fractures. There were 5 patients with single maxillary dentition defects, 2 with single mandibular dentition defects, and 8 with both maxillary and mandibular dentition defects. To reconstruct the correct 3D jaw positional relationship, 5 patients underwent Le Fort I osteotomy of the maxilla, 3 underwent bilateral sagittal split ramus osteotomy of the mandible, 4 underwent open reduction and internal fixation for old jaw fractures, 3 underwent temporomandibular joint surgery, and 4 underwent distraction osteogenesis. All patients underwent jawbone augmentation, of whom 4 patients underwent a free composite vascularized bone flap (26.66%) and the remaining patients underwent local alveolar bone augmentation. Free gingival graft and connective tissue graft were the main methods for soft tissue augmentation (73.33%).</p><p>The 15 patients received 81 implants, of whom 11 patients received implant-supported fixed dentures and 4 received implant-supported removable dentures. The survival rate of all implants was 93.82%. The final imageological examination of 15 patients confirmed that the malocclusion was corrected, and the clinical treatment ultimately achieved occlusal function reconstruction. The patient satisfaction questionnaire survey showed that they were satisfied with the efficacy, phonetics, aesthet","PeriodicalId":51555,"journal":{"name":"Chinese Journal of Traumatology","volume":"27 5","pages":"Pages 272-278"},"PeriodicalIF":1.8,"publicationDate":"2024-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1008127524000300/pdfft?md5=8366c5cc1bba2a81140dffd807da80bc&pid=1-s2.0-S1008127524000300-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140186260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}