Chinese Journal of Traumatology最新文献

{"title":"Acute portal vein thrombosis in an isolated, blunt, minor liver injury near the porta hepatis","authors":"Onchuda Wongweerakit,&nbsp;Osaree Akaraborworn,&nbsp;Burapat Sangthong,&nbsp;Komet Thongkhao","doi":"10.1016/j.cjtee.2023.09.003","DOIUrl":"10.1016/j.cjtee.2023.09.003","url":null,"abstract":"<div><div>Portal vein thrombosis (PVT) secondary to blunt abdominal trauma associated with liver injury is extremely rare in healthy individuals as well as in minor liver injury, and it carries a high rate of morbidity and mortality. Moreover, acute asymptomatic PVT is difficult to diagnose. We present a young trauma patient with isolated minor liver injury associated with acute PVT. A 27-year-old man presented to the emergency department after a motor vehicle collision. His primary survey findings were unremarkable. His secondary survey showed a large contusion (7 × 7 cm²) at the epigastrium with marked tenderness and localized guarding. The CT angiography of the whole abdomen revealed liver injury grade 3 in hepatic segments 2/3 and 4b (according to the American Association for the Surgery of Trauma classification) extending near the porta hepatis with patent hepatic and portal veins and without other solid organ injury. The follow-up CT of the whole abdomen on post-injury day 7 showed a 1.8-cm thrombus in the left portal vein with patent right portal and hepatic veins, and a decreased size of the hepatic lacerations. A liver function test was repeated on post-injury day 4, and it revealed improved transaminitis. The patient received intravenous anticoagulant therapy with low-molecular-weight heparin according to weight-based dosing for treatment. The CT of the whole abdomen performed 2 weeks after anticoagulant therapy showed small residual thrombosis in the left portal vein. The patient received intravenous anticoagulant therapy for a total of 3 months. On the follow-up visits at 1 month, 2 months, 6 months, and 1 year after the injury, the patients did not have any detectable abnormal symptoms. PVT post-blunt minor liver injury is an extremely rare complication. If the thrombosis is left untreated, serious morbidity and mortality can ensue. However, its diagnosis in asymptomatic patients is still challenging. Periodic imaging is necessary for highly suspected PVT, especially in liver injury with lacerations close to the porta hepatis, even in cases of a minor injury.</div></div>","PeriodicalId":51555,"journal":{"name":"Chinese Journal of Traumatology","volume":"28 1","pages":"Pages 76-78"},"PeriodicalIF":1.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41221794","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A novel arterial coupler with non-return snap-fit connection approach optimized arterial end-to-end anastomotic technique: An experimental study","authors":"Hong-Bo Guo ,&nbsp;Mo-Fei Wang ,&nbsp;Ren-Qi Yin ,&nbsp;Kang-Kang Zhi","doi":"10.1016/j.cjtee.2024.09.006","DOIUrl":"10.1016/j.cjtee.2024.09.006","url":null,"abstract":"<div><h3>Purpose</h3><div>Hand-sewn anastomosis as the gold standard of vascular anastomosis cannot fully meet the requirements of vascular anastomosis in speed and quality. Various vascular couplers have been developed to ameliorate this situation. Most of them are mainly used for venous anastomosis rather than arterial anastomosis. Although it is generally acknowledged that in almost all operations involving vascular reconstruction, it is the arteries that need to be anastomosed faster and more accurately and not the veins. A dedicated device is needed for creating arterial anastomosis in an easy, timesaving, less damaging but reliable procedure. Therefore, we plan to develop a novel arterial coupler device and test pre-clinical safety and effectiveness.</div></div><div><h3>Methods</h3><div>In this cohort study, the rationality of this novel arterial coupler was preliminarily tested by finite element analysis before it was manufactured. Several factors restrict the use of vascular couplers in arterial anastomosis, such as arterial eversion, fixation, etc. The manufactured arterial couplers underwent <em>in vitro</em> and <em>in vivo</em> experiments. <em>In vitro</em>, isolated arteries of beagles were anastomosed with the assistance of an arterial coupler, and the anastomosed arteries were evaluated through anti-traction tests. In animal experiments, the bilateral femoral arteries of 5 beagles served as a control group. After dissection, the femoral artery on one side was randomly selected to be anastomosed with a quick arterial coupler (QAC) (QAC group), and the femoral artery on the other side was anastomosed by the same person using an end-to-end suture technique with a 6-0 Prolene suture (suture group). The bilateral femoral arteries of 5 beagles were used for coupler-assisted anastomosis and hand-sewn anastomosis <em>in vivo</em>, respectively. Success rate, blood loss, anastomotic time, clamp time, total operation time, and patency rate were recorded. The patency of anastomosed arteries was assessed using vascular Doppler ultrasound, electromagnetic flowmeter, and pathological examination (6 weeks after surgery).</div></div><div><h3>Results</h3><div>As a novel arterial coupler, QAC was successfully designed and manufactured by using poly lactic-co-glycolic acid raw materials and 3-dimensions printing technology. Its rationality was preliminarily tested through finite element analysis and related mechanical analysis methods. The isolated arteries were successfully anastomosed with the assistance of QAC <em>in vitro</em> testing, which showed good anti-traction properties. In animal studies, QAC-assisted arterial anastomosis has superior profiles compared to hand-sewn anastomosis in anastomotic time (7.80 ± 1.41 <em>vs</em>. 16.38 ± 1.04 min), clamp time (8.80 ± 1.41 <em>vs</em>. 14.14 ± 1.57 min), and total operation time (46.64 ± 2.38 <em>vs</em>. 51.96 ± 3.65 min). The results of electromagnetic flowmeter, vascular Doppler ultrasound, a","PeriodicalId":51555,"journal":{"name":"Chinese Journal of Traumatology","volume":"28 1","pages":"Pages 13-21"},"PeriodicalIF":1.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142480426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"FM1-Editorial board","authors":"","doi":"10.1016/S1008-1275(24)00159-7","DOIUrl":"10.1016/S1008-1275(24)00159-7","url":null,"abstract":"","PeriodicalId":51555,"journal":{"name":"Chinese Journal of Traumatology","volume":"28 1","pages":"Page i"},"PeriodicalIF":1.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143173318","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Guide for Author","authors":"","doi":"10.1016/S1008-1275(24)00165-2","DOIUrl":"10.1016/S1008-1275(24)00165-2","url":null,"abstract":"","PeriodicalId":51555,"journal":{"name":"Chinese Journal of Traumatology","volume":"28 1","pages":"Pages I-V"},"PeriodicalIF":1.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143171433","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Stent-graft implantation for late postpancreatectomy hemorrhage after pancreatoduodenectomy","authors":"Xiaoye Li ,&nbsp;Shibo Xia ,&nbsp;Liangxi Yuan ,&nbsp;Lei Zhang ,&nbsp;Chao Song ,&nbsp;Xiaolong Wei ,&nbsp;Qingsheng Lu","doi":"10.1016/j.cjtee.2024.08.009","DOIUrl":"10.1016/j.cjtee.2024.08.009","url":null,"abstract":"<div><h3>Purpose</h3><div>Postpancreatectomy hemorrhage (PPH) is a life-threatening complication after pancreatoduodenectomy. Stent-graft implantation is an emerging treatment option for PPH. This study reports the outcome of PPH treated with stent-graft implantation.</div></div><div><h3>Methods</h3><div>This was a single-center, retrospective study. Between April 2020 and December 2023, 1723 pancreatectomy cases were collected while we screened 12 cases of PPH after pancreatoduodenectomy treated with stent-graft implantation. Patients' medical and radiologic images were retrospectively reviewed. Technical and clinical success, complications, and stent-graft patency were evaluated. Continuous data are reported as means ± standard deviation when normally distributed or as median (Q₁, Q₃) when the data is non-normal distributed. Categorical data are reported as <em>n</em> (%). A <em>p</em> &lt; 0.05 was considered statistically significant. Kaplan-Meier estimates were used for stent patency and patients’ survival.</div></div><div><h3>Results</h3><div>Pancreatic fistula was identified in 6 cases (50.0%), and pseudoaneurysm was identified in 3 cases (25.0%), including pancreatic fistula together with pseudoaneurysm in 1 case (8.3%). All pseudoaneurysm or contrast extravasation sites were successfully excluded with patent distal perfusion, thus technical success was achieved in all cases. The overall survival rate at 6 months and 1 year was 91.7% and 78.6%, respectively. One patient had herniation of the small intestine into the thoracic cavity, which caused a broad thoracic and abdominal infection and died during hospitalization. Rebleeding occurred at the gastroduodenal artery stump in 1 case after stent-graft implantation for the splenic artery and was successfully treated with another stent-graft implantation. Two cases of asymptomatic stent-graft occlusion were observed at 24.6 and 26.3 after the operation, respectively.</div></div><div><h3>Conclusions</h3><div>With suitable anatomy, covered stent-graft implantation is an effective and safe treatment option for PPH with various bleeding sites and causes.</div></div>","PeriodicalId":51555,"journal":{"name":"Chinese Journal of Traumatology","volume":"28 1","pages":"Pages 7-12"},"PeriodicalIF":1.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142644667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Central venous oxygen saturation changes as a reliable predictor of the change of CI in septic shock: To explore potential influencing factors","authors":"Ran An ,&nbsp;Xi-Xi Wan ,&nbsp;Yan Chen ,&nbsp;Run Dong ,&nbsp;Chun-Yao Wang ,&nbsp;Wei Jiang ,&nbsp;Li Weng ,&nbsp;Bin Du","doi":"10.1016/j.cjtee.2024.05.001","DOIUrl":"10.1016/j.cjtee.2024.05.001","url":null,"abstract":"<div><h3>Purpose</h3><div>Assessing fluid responsiveness relying on central venous oxygen saturation (ScvO₂) yields varied outcomes across several studies. This study aimed to determine the ability of the change in ScvO₂ (ΔScvO₂) to detect fluid responsiveness in ventilated septic shock patients and potential influencing factors.</div></div><div><h3>Methods</h3><div>In this prospective, single-center study, all patients conducted from February 2023 to January 2024 received fluid challenge. Oxygen consumption was measured by indirect calorimetry, and fluid responsiveness was defined as an increase in cardiac index (CI) ≥ 10% measured by transthoracic echocardiography. Multivariate linear regression analysis was conducted to evaluate the impact of oxygen consumption, arterial oxygen saturation, CI, and hemoglobin on ScvO₂ and its change before and after fluid challenge. The Shapiro-Wilk test was used for the normality of continuous data. Data comparison between fluid responders and non-responders was conducted using a two-tailed Student <em>t</em>-test, Mann Whitney U test, and Chi-square test. Paired <em>t</em>-tests were used for normally distributed data, while the Wilcoxon signed-rank test was used for skewed data, to compare data before and after fluid challenge.</div></div><div><h3>Results</h3><div>Among 49 patients (31 men, aged (59 ± 18) years), 27 were responders. The patients had an acute physiology and chronic health evaluation II score of 24 ± 8, a sequential organ failure assessment score of 11 ± 4, and a blood lactate level of (3.2 ± 3.1) mmol/L at enrollment. After the fluid challenge, the ΔScvO₂ (mmHg) in the responders was greater than that in the non-responders (4 ± 6 <em>vs.</em> 1 ± 3, <em>p</em> = 0.019). Multivariate linear regression analysis suggested that CI was the only independent influencing factor of ScvO₂, with <em>R</em>^<em>2</em> = 0.063, <em>p</em> = 0.008. After the fluid challenge, the change in CI became the only contributing factor to ΔScvO₂ (<em>R</em>^<em>2</em> = 0.245, <em>p</em> &lt; 0.001). ΔScvO₂ had a good discriminatory ability for the responders and non-responders with a threshold of 4.4% (area under the curve = 0.732, <em>p</em> = 0.006).</div></div><div><h3>Conclusion</h3><div>ΔScvO₂ served as a reliable surrogate marker for ΔCI and could be utilized to assess fluid responsiveness, given that the change in CI was the sole contributing factor to the ΔScvO₂. In stable hemoglobin conditions, the absolute value of ScvO₂ could serve as a monitoring indicator for adequate oxygen delivery independent of oxygen consumption.</div></div>","PeriodicalId":51555,"journal":{"name":"Chinese Journal of Traumatology","volume":"28 1","pages":"Pages 43-49"},"PeriodicalIF":1.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141054621","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluating the effectiveness of immediate vs. elective thoracic endovascular aortic repair for blunt thoracic aortic injury","authors":"Zhaohui Hua ,&nbsp;Baoning Zhou ,&nbsp;Wenhao Xue ,&nbsp;Zhibin Zhou ,&nbsp;Jintao Shan ,&nbsp;Lei Xia ,&nbsp;Yunpeng Luo ,&nbsp;Yiming Chai ,&nbsp;Zhen Li","doi":"10.1016/j.cjtee.2024.08.002","DOIUrl":"10.1016/j.cjtee.2024.08.002","url":null,"abstract":"&lt;div&gt;&lt;h3&gt;Purpose&lt;/h3&gt;&lt;div&gt;To evaluate the relationship between the timing of thoracic endovascular aortic repair (TEVAR) for blunt thoracic aortic injury (BTAI) and prognosis.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Methods&lt;/h3&gt;&lt;div&gt;This is a single-center retrospective cohort study. Patients who received TEVAR for BTAI at our institution from October 2016 to September 2023 were divided into 2 categories depending on the injury severity score (ISS) (≤ 25 &lt;em&gt;vs.&lt;/em&gt; &gt; 25) and when the TEVAR was performed for BTAI (within 24 h &lt;em&gt;vs.&lt;/em&gt; after 24 h), respectively. The analysis included all patients who received TEVAR treatment after being diagnosed with BTAI through whole-body CT angiography. Patients treated with open repair and non-operative management were excluded. After propensity-score matching for various factors, outcomes during hospitalization and follow-up were compared. These factors included demographics, comorbidities, concomitant injuries, cause and location of aortic injury, Glasgow coma scale score, society for vascular surgery grading, hemoglobin concentration, creatinine concentration, shock, systolic blood pressure, and heart rate at admission. The comparison was conducted using SPSS 26 software. Continuous variables were presented as either the mean ± standard deviation or median (Q&lt;sub&gt;1&lt;/sub&gt;, Q&lt;sub&gt;3&lt;/sub&gt;), and were compared using either the &lt;em&gt;t&lt;/em&gt;-test or the Mann-Whitney &lt;em&gt;U&lt;/em&gt; test. Categorical variables were expressed as &lt;em&gt;n&lt;/em&gt; (%), and comparisons were made between the 2 groups using the χ&lt;sup&gt;2&lt;/sup&gt; test or Fisher’s exact test. Statistical significance was defined as a 2-sided &lt;em&gt;p&lt;/em&gt; &lt; 0.05.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Results&lt;/h3&gt;&lt;div&gt;In total, 110 patients were involved in the study, with 65 (59.1%) patients having ISS scores &gt; 25 and 32 (29.1%) receiving immediate TEVAR. The perioperative overall mortality rate in the group with ISS &gt; 25 was significantly higher than that in the group with ISS ≤ 25 (11 (16.9%) &lt;em&gt;vs.&lt;/em&gt; 2 (4.4%), &lt;em&gt;p&lt;/em&gt; &lt; 0.001). Upon admission, the elective group exhibited a notably higher Glasgow coma scale score (median (Q&lt;sub&gt;1&lt;/sub&gt;, Q&lt;sub&gt;3&lt;/sub&gt;)) compared to the immediate group (15 (12, 15) &lt;em&gt;vs.&lt;/em&gt; 13.5 (9, 15), &lt;em&gt;p&lt;/em&gt; = 0.039), while the creatinine concentration (median (Q&lt;sub&gt;1&lt;/sub&gt;, Q&lt;sub&gt;3&lt;/sub&gt;)) at admission was significantly higher in the immediate group (90.5 (63.8, 144.0) &lt;em&gt;vs.&lt;/em&gt; 71.5 (58.3, 80.8), &lt;em&gt;p&lt;/em&gt; = 0.012). The final sample included 52 matched patients. Complications occurred significantly less frequently in the elective group compared to the immediate group (16 (50.0%) &lt;em&gt;vs.&lt;/em&gt; 3 (10.0%), &lt;em&gt;p&lt;/em&gt; &lt; 0.001). Single-factor analysis of variance showed that complications in hospitalized patients were significantly associated with immediate TEVAR as the sole independent risk factor (odds ratio: 9.000, 95% confidence interval: 2.266–35.752, &lt;em&gt;p&lt;/em&gt; = 0.002).&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Conclusion&lt;/h3&gt;&lt;div&gt;In this propensity-score matched anal","PeriodicalId":51555,"journal":{"name":"Chinese Journal of Traumatology","volume":"28 1","pages":"Pages 22-28"},"PeriodicalIF":1.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142047451","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"4-Octyl itaconate inhibits synovitis in the mouse model of post-traumatic osteoarthritis and alleviates pain","authors":"Yu-Zhen Tang ,&nbsp;Wan Chen ,&nbsp;Bao-Yun Xu ,&nbsp;Gang He ,&nbsp;Xiu-Cheng Fan ,&nbsp;Kang-Lai Tang","doi":"10.1016/j.cjtee.2024.10.001","DOIUrl":"10.1016/j.cjtee.2024.10.001","url":null,"abstract":"&lt;div&gt;&lt;h3&gt;Purpose&lt;/h3&gt;&lt;div&gt;To investigate the pathological changes of the synovium in mice with post-traumatic osteoarthritis (PTOA) treated with 4-octyl itaconate (4-OI) and evaluate the therapeutic effects of 4-OI.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Methods&lt;/h3&gt;&lt;div&gt;In the phenotypic validation experiment, the mice were randomly divided into 3 groups: wild-type (WT) group, sham group, and destabilization of the medial meniscus (DMM) group. Through MRI, micro-CT, and histological analysis, it was determined that the DMM surgery induced a mouse PTOA model with significant signs of synovitis. At 12 weeks post-DMM surgery, synovial tissues from the DMM group and WT group mice were collected for ribonucleic acid sequencing analysis. In the 4-OI treatment experiment, mice were randomly divided into the sham group, DMM group, DMM + 4-OI (50 mg/kg) group, and DMM + 4-OI (100 mg/kg) group. Von Frey tests and open field tests were conducted at intervals during the 12 weeks following the DMM surgery. After 12 weeks of surgery, the efficacy of 4-OI treatment on PTOA in mice was evaluated using MRI, micro-CT, histological analysis, and quantitative real-time polymerase chain reaction. Finally, we utilized network pharmacology analysis to predict the mechanism of 4-OI in treating PTOA synovitis and conducted preliminary validation. Statistical analysis was performed using one-way ANOVA and the Kruskal-Wallis test. Difference was considered statistically significant at &lt;em&gt;p&lt;/em&gt; &lt; 0.05.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Results&lt;/h3&gt;&lt;div&gt;The DMM surgery effectively induced a PTOA mouse model, which displayed significant symptoms of synovitis. These symptoms included a notable increase in both the number of calcified tissues and osteophytes (&lt;em&gt;p&lt;/em&gt; &lt; 0.001), an enlargement of the calcified meniscus and synovial tissue volume (&lt;em&gt;p&lt;/em&gt; &lt; 0.001), and thickening of the synovial lining layer attributable to M1 macrophage accumulation (&lt;em&gt;p&lt;/em&gt; = 0.035). Additionally, we observed elevated histological scores for synovitis (&lt;em&gt;p&lt;/em&gt; &lt; 0.001). Treatment with 4-OI inhibited the thickening of M1 macrophages in the synovial lining layer of PTOA mice (&lt;em&gt;p&lt;/em&gt; &lt; 0.001) and reduced fibrosis in the synovial stroma (&lt;em&gt;p&lt;/em&gt; = 0.004). Furthermore, it reduced the histological scores of knee synovitis in PTOA mice (&lt;em&gt;p&lt;/em&gt; = 0.006) and improved the inflammatory microenvironment associated with synovitis. Consequently, this treatment alleviated pain in PTOA mice (&lt;em&gt;p&lt;/em&gt; &lt; 0.001) and reduced spontaneous activity (&lt;em&gt;p&lt;/em&gt; = 0.003). Bioinformatics and network pharmacology analyses indicated that 4-OI may exert its therapeutic effects by inhibiting the differentiation of synovial Th17 cells. Specifically, compared to the lipopolysaccharide stimulation group, 4-OI reduced the levels of positive regulatory factors of Th17 cell differentiation (IL-1: &lt;em&gt;p&lt;/em&gt; &lt; 0.001, IL-6: &lt;em&gt;p&lt;/em&gt; &lt; 0.001), key effector molecules (IL-17A: &lt;em&gt;p&lt;/em&gt; &lt; 0.001, IL-17F: &lt;em&gt;p&lt;/","PeriodicalId":51555,"journal":{"name":"Chinese Journal of Traumatology","volume":"28 1","pages":"Pages 50-61"},"PeriodicalIF":1.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142693750","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Recent advances in the management of chronic ankle instability","authors":"Yimeng Yang,&nbsp;Yang Wu,&nbsp;Wenhui Zhu","doi":"10.1016/j.cjtee.2024.07.011","DOIUrl":"10.1016/j.cjtee.2024.07.011","url":null,"abstract":"<div><div>Ankle sprains are the most common lesion of the ankle joint which might result in chronic ankle instability (CAI). Significant strides have been taken to enhance our comprehension of the underlying mechanisms of CAI, as the exploration of novel surgical techniques and the identification of previously unrecognized anatomical components. The present review aims to provide an extensive overview of CAI, encompassing its pathophysiology, epidemiology, clinical assessment, treatment, and rehabilitation. Treatment of CAI requires a multifaceted algorithm, involving historical analysis, clinical evaluations, and diagnostic imaging. Surgical interventions for CAI primarily involve the anatomical and/or non-anatomical reconstruction and/or repair of the anterior talofibular ligament. Anatomical repair has exhibited superior functional outcomes and a reduced risk of secondary osteoarthritis compared to non-anatomical repair. Non-anatomical approaches fall short of replicating the normal biomechanics of the anterior talofibular ligament, potentially leading to postoperative stiffness. This review seeks to academically review and up-to-date literature on this issue, tailored for clinical practice, with the intent of aiding surgeons in staying abreast of this critical subject matter.</div></div>","PeriodicalId":51555,"journal":{"name":"Chinese Journal of Traumatology","volume":"28 1","pages":"Pages 35-42"},"PeriodicalIF":1.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142710847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Two cases of complex traumatic aortic dissection combined with multiple organ injuries","authors":"Qingpeng Song,&nbsp;Lili Bao,&nbsp;Xuejun Wu,&nbsp;Bingqi Liu,&nbsp;Maohua Wang","doi":"10.1016/j.cjtee.2024.08.001","DOIUrl":"10.1016/j.cjtee.2024.08.001","url":null,"abstract":"<div><div>Traumatic aortic injury (TAI) is an acute, critical, and severe disease, and then combined with multiple organ damage, it is even more dangerous. TAI progresses very rapidly, with a pre-hospital mortality rate of 57%–80%, and even when arriving at the hospital, more than one-third of the patients die within 4 h, and it is the 2nd leading cause of death in individuals aged 4−34 years. In addition, the incidence of TAI combined with injury was 81.4%. Therefore, early diagnosis, expeditious surgery, and timely and effective multidisciplinary cooperation are essential for successful rescue. The authors report 2 patients with acute traumatic aortic dissection combined with multiple organ injuries and treated with emergency endovascular surgery to discuss their clinical characteristics and treatment experience, and to provide experience in the diagnosis and treatment of such patients.</div></div>","PeriodicalId":51555,"journal":{"name":"Chinese Journal of Traumatology","volume":"28 1","pages":"Pages 29-34"},"PeriodicalIF":1.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141989446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}