The Natural Products Journal最新文献

{"title":"Improvement of Taxane Biosynthesis in Cell Suspension Culture of Taxus\u0000baccata after Elicitation with Titania-graphene Oxide Nanocomposite and\u0000Coronatine","authors":"Rahimeh Hemmati Gougeh, Reza Fatahi, Majid Shokrpour, Mohammadreza Naghavi, Alidad Varshochi, M. Mirjalili, J. Nasiri","doi":"10.2174/0122103155282541240624050103","DOIUrl":"https://doi.org/10.2174/0122103155282541240624050103","url":null,"abstract":"\u0000\u0000There is a research gap about applying titania–graphene oxide (GO-TiO2)\u0000nanocomposite and coronatine as elicitors in the cell suspension culture of T. baccata.\u0000\u0000\u0000\u0000The effects of two elicitors of GO-TiO2 (30 µg/L) and coronatine (10 µM) were examined\u0000to improve the production of five different taxanes in the cell suspension culture of T. baccata.\u0000\u0000\u0000\u0000The suspension culture was prepared from the callus of T. baccata leaf explant. Next, both\u0000elicitors of coronatine (10 µM) and GO-TiO2 (30 µg/L) were applied, sampling occurred 2, 4, 16\u0000days after elicitation, and all five taxanes were quantified using HPLC.\u0000\u0000\u0000\u0000The amounts of 10-DAB III ranged from 0.84 mg/L (for control) to 9.17 mg/L (day 16 after\u0000elicitation with GO-TiO2). The production of BAC III ranged from zero (for control) to 7.69 mg/L\u0000(day 4 with GO-TiO2). The maximum production of 10-deacetyltaxol was observed in control on day\u000016 with the amount of 1.85 mg/L, followed by a lower level of 0.825 mg/L on day 2 with coronatine\u0000treatment. Considering cephalomannine, only elicitation of GO-TiO2 over all three different sampling\u0000times (i.e., days 2, 4, and 16) resulted in sensible quantities. The maximum magnitudes of taxol were\u0000acquired when GO-TiO2 was applied on day 4 and day 16 (1.345 mg/L and 0.965 mg/L, respectively).\u0000\u0000\u0000\u0000The results indicated the potential positive effects of both elicitors, particularly GOTiO2 nanocomposite, to improve taxanes production.\u0000","PeriodicalId":515404,"journal":{"name":"The Natural Products Journal","volume":"65 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141684230","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correlation Between the Amount of Total Phenolic Contents and\u0000Antioxidant Activity of Mediterranean Shrubs: Are Phenols a Good\u0000Indicator of the Antioxidant Activity of These Species?","authors":"Natividad Chaves, Mercedes Navarro, Mario Flores, J. C. Alías","doi":"10.2174/0122103155305002240415114257","DOIUrl":"https://doi.org/10.2174/0122103155305002240415114257","url":null,"abstract":"\u0000\u0000Cells generate reactive oxygen species (ROS), which cause oxidative stress.\u0000Such stress is counteracted by a complex antioxidant system, which includes molecules of the secondary\u0000metabolism of plants, mainly phenols. Several studies attribute the antioxidant activity of a\u0000species to these compounds, although, in other studies, this relationship is not clear.\u0000\u0000\u0000\u0000The aim of this study was to determine whether the amount of total phenols is a good indicator\u0000of the antioxidant activity of a species.\u0000\u0000\u0000\u0000The present study quantified the total phenols and antioxidant activity measured by DPPH\u0000and ABTS methods of 18 species of Mediterranean scrubs and established the correlation between\u0000these two parameters.\u0000\u0000\u0000\u0000The obtained results showed that there was a wide variability in the content of phenols\u0000among the analyzed species, with Cistus salviifolius and Nerium oleander presenting the largest and\u0000smallest amount of total phenols, respectively (0.043 and 0.004 gallic acid equivalent (mg/mg dw)).\u0000A cluster analysis differentiated these species into two groups with significantly different amounts of\u0000phenols. The species that constitute Group I presented an average amount of 0.029 gallic acid equivalent\u0000(mg/mg dw), and that of the species of Group II was 0.011±0.003 gallic acid equivalent (mg/mg\u0000dw). The relationship between the antioxidant activity quantified in each species and its content of\u0000total phenols showed a positive and significant correlation; however, when considering the two\u0000groups of species, the significant correlation between these parameters depends on the species group,\u0000the extract concentration used, and the method employed to quantify the antioxidant activity.\u0000\u0000\u0000\u0000These results indicate that it would not be correct to generalize that there is a significant\u0000correlation between the amount of total phenols and the antioxidant activity. Therefore, total phenol\u0000content cannot be used as a single indicator of the antioxidant activity of a species.\u0000","PeriodicalId":515404,"journal":{"name":"The Natural Products Journal","volume":"7 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141687297","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Updates on Tropical Medicinal Plant Tinospora cordifolia as an\u0000Antimicrobial Shrub to Combat Respiratory Infections","authors":"Mahima Beohar, Megha Verma, Amita Verma, Vandana Gupta","doi":"10.2174/0122103155321163240620101820","DOIUrl":"https://doi.org/10.2174/0122103155321163240620101820","url":null,"abstract":"\u0000\u0000Respiratory infections are a universal issue with high death rates caused by several pathogens. It makes it obligatory to explore novel antimicrobial drugs to cure lung infections. Phytochemicals, which are herbal compounds found in plants, exhibit antimicrobial properties and contain\u0000substances like tannins, terpenoids, flavonoids, etc. Now, researchers have opted for novel strategies\u0000for drug invention through the screening of medicinal plants. These plants offer a lavish source of\u0000new structures and phyto moieties, making them precious in the development of effective treatments.\u0000Many current researchers recommend medicinal plant formulations to cure different respiratory disorders. Among these are Tinospora cordifolia (Thunb.) Miers (T. cordifolia) shrubs. The plant T.\u0000cordifolia is mainly claimed for its antispasmodic, antipyretic, antineoplastic, hypolipidemic, hypoglycemic, immunopotentiating, and hepatoprotective pharmacological properties. This review provides insight into T. cordifolia, which plays a significant role in combating infectious ailments and\u0000its significance in maintaining the health of mankind. This review article recapitulates the plant TC\u0000and specifies different bioactive components that showed antimicrobial action. The present study\u0000outlined various investigations that have been done on T. cordifolia, i.e., in-silico, toxicity, and antimicrobial, which will explore the opportunity in the development of novel medications against microbial infections. In addition, this study depicts the application of T. cordifolia in culinary, beverage\u0000and marketed products that were found helpful in the treatment of various disorders and recent updates on T. cordifolia. The literature acknowledges that this natural antimicrobial plant will help to\u0000lay the foundation for upgrading exhaustive pharmacological and pharmaceutical studies to better\u0000understand the clinical relevance and application of T. cordifolia in the prevention and treatment of\u0000life-threatening respiratory infections.\u0000","PeriodicalId":515404,"journal":{"name":"The Natural Products Journal","volume":"64 s91","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141688427","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bovine Colostrum: Unveiling its Potent Health Benefits and Emerging Trends in Optimizing Well-being","authors":"Archna Singh, Dr. Avijit Mazumder, Saumya Das, Anmol Kanda, Vishnu Prabhakar, Rashmi Mishra, MVNL Chaitanya","doi":"10.2174/0122103155310246240603074349","DOIUrl":"https://doi.org/10.2174/0122103155310246240603074349","url":null,"abstract":"\u0000\u0000Bovine colostrum, also known as cow colostrum, is the first milk produced by cows after\u0000giving birth. It is packed with natural macro-micronutrients, immunoglobulins, peptides, and proteins\u0000and has been utilized in traditional medicine for centuries to treat a range of illnesses and problems.\u0000Its therapeutic advantages are particularly significant in the treatment of respiratory problems,\u0000growth factor augmentation, and other conditions. Numerous preclinical and clinical research studies\u0000have demonstrated its therapeutic effects, including its ability to promote well-being, treat medical\u0000conditions, and support animal husbandry. Bovine colostrum may assist therapy against COVID-19\u0000due to its potential antiviral properties, which can slow the course of the disease. Bovine colostrum\u0000contains bioactive components such as lactoferrin, which has antibacterial, anti-inflammatory, and\u0000antiviral properties. Additionally, bovine colostrum may boost both the adaptive and innate immune\u0000systems of humans. Colostrum's chemical composition differs from milk, with higher concentrations\u0000of nutrients and physiologically active compounds such as enzymes, growth factors, immunoglobulins,\u0000and hormones. The colostrum is crucial for the development of a newborn calf's immune system,\u0000and the initial section of the colostrum has the highest concentration of insulin-like growth factors\u0000(IGFs), which rapidly decline after that. While cow colostrum is generally considered safe when\u0000consumed orally, it should be noted that rectal administration can function as an enema, and consuming\u0000colostrum from infected cows can result in severe disorders such as bovine spongiform encephalitis\u0000(BSE), also known as \"mad cow disease\" or other disorders. Therefore, it is crucial to use proper\u0000sanitation and dosage of cow/ bovine colostrum for food or medicinal usage to avoid potential adverse\u0000effects. This review article highlights the medical applications, constituents, and benefits of\u0000cow colostrum, showcasing its potential as a natural remedy for health and wellness. However, it is\u0000essential to exercise caution and obtain bovine colostrum from safe sources for optimal therapeutic\u0000benefits.\u0000","PeriodicalId":515404,"journal":{"name":"The Natural Products Journal","volume":"37 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141345210","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Explicating the Phyto-pharmacological Virtues of Solanum torvum Swartz: A Contemporary Update","authors":"Madhukar Garg, L. Vaid, Parth Sharma, Nidhi Rani, Geeta Deswal, Sonam Grewal, A. Dhingra, Navin Kumar Tailor, A. Grewal","doi":"10.2174/0122103155316286240603062302","DOIUrl":"https://doi.org/10.2174/0122103155316286240603062302","url":null,"abstract":"\u0000\u0000Solanum torvum Swartz has been considered to shed light on the diverse phytochemical\u0000and pharmacological abilities relevant to its profound health benefits. The present review attempted\u0000to emphasize the phytochemical and pharmacological investigations on Solanum torvum Swartz.\u0000Furthermore, the investigators aimed to provide an elaborative outline regarding the tissue culture\u0000studies of the mentioned plant. This plant has been reported to contain various types of\u0000phytoconstituents, including alkaloids, alkaloid glycosides, allenes, coumarins, diterpenoids, fatty\u0000acid esters, fatty acids, flavonoids, isoflavones, furan derivatives, glycosides, lignans,\u0000monoterpenoids, phenolic acids, sesquiterpenoids, saponins, steroidal derivatives, and triterpenoids.\u0000An array of pharmacological activities has been reported for this plant, including hypotensive, antiplatelet\u0000aggregation, anti-ulcerogenic, antimicrobial, analgesic, anti-inflammatory, antioxidant,\u0000immunomodulatory, wound healing, antiparasitic, larvicidal, antimalarial, anti-trichomonal,\u0000leishmanicidal, anticancer, diuretic, anxiolytic, antidepressant, antidiabetic, anthelmintic, thrombolytic,\u0000antiarthritic, antihyperlipidemic, hepato-protective, anti-Alzheimer, and cardioprotective activities.\u0000This work provides researchers with up-to-date information on the health benefits of plants\u0000attributed to their bioactive compounds. The information highlights the need for further research to\u0000develop novel formulations using these bioactive principles for potential treatment and preventive\u0000medicine applications targeting various ailments.\u0000","PeriodicalId":515404,"journal":{"name":"The Natural Products Journal","volume":"47 18","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141349463","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Systematic Detoxification of Copper-induced Toxicity by Methanolic Extracts of Anacyclus pyrethrum (L) in Zebrafish Model","authors":"Vineesh Suresh, Kirankumar S.I, Shahjahan A, S. Jamuna, Kirubakaran Rangasamy, Dannie Macrin, K. ArulJothi","doi":"10.2174/0122103155308142240602120718","DOIUrl":"https://doi.org/10.2174/0122103155308142240602120718","url":null,"abstract":"\u0000\u0000Anacyclus pyrethrum is used in Ayurveda to treat various ailments, ranging\u0000from toothache to female infertility. However, the molecular mechanisms of its medicinal properties\u0000are obscure and need exploratory studies.\u0000\u0000\u0000\u0000We aimed to investigate the molecular mechanisms associated with the medicinal properties\u0000of A. pyrethrum using zebrafish as an in vivo model. We have employed in silico, in vitro, and in\u0000vivo approaches to elucidate the anti-inflammatory, antioxidant, and cytoprotective functions of the\u0000methanolic extracts of A. pyrethrum. In silico analyses were carried out using Prediction of Activity\u0000Spectra for Substances (PASS), Molecular Inspiration, Swiss Absorption, Distribution, Metabolism,\u0000Excretion and Toxicity - ADME (SWISSADME), Absorption, Distribution, Metabolism, Excretion,\u0000and Toxicity - Structure-Activity Relationship(ADMETSar) and molecular docking tools to prove\u0000the anti-inflammatory effects of the bioactive components of A. pyrethrum.\u0000\u0000\u0000\u0000Our results indicate that the bioactive components of A. pyrethrum have pharmaceutical\u0000properties with high intestinal absorption and greater bioavailability. Further, in vitro and in vivo\u0000results support the anti-inflammatory, antioxidant, and antitoxic effects of methanolic extract of A.\u0000pyrethrum via suppressing the levels of the inflammatory and Reactive oxygen species biomarkers,\u0000including Lactate Dehydrogenase, Myeloperoxidase, Nitric Oxide, and Lipid peroxidase respectively.\u0000\u0000\u0000\u0000The results obtained from three different approaches in this study highlight the potential\u0000anti-inflammatory, antitoxic, and antioxidant effects of A. pyrethrum.\u0000","PeriodicalId":515404,"journal":{"name":"The Natural Products Journal","volume":"109 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141352149","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Add-on Therapy with Melatonin in the Acute Bipolar Mania Treatment:\u0000Results of a Randomized, Placebo-controlled Trial","authors":"M. Mehrpooya, Zahra Ghasemian, Kiumarth Amini, Kimia Bakhtiari, Maryam Zamanirafe, Amir Keshavarzi, Y. Mohammadi, Davoud Ahmadimoghaddam","doi":"10.2174/0122103155307953240529111039","DOIUrl":"https://doi.org/10.2174/0122103155307953240529111039","url":null,"abstract":"\u0000\u0000Prior research indicates that disruptions in melatonin secretion\u0000levels and timing could be linked to the pathophysiology of bipolar disorder. Our study aimed to assess\u0000the effectiveness of melatonin as an adjunctive therapy to classical mood stabilizers in addressing sleep\u0000impairment and mood symptoms in bipolar patients currently experiencing manic episodes.\u0000\u0000\u0000\u0000Fifty-eight hospitalized patients, with a mean age of 38.04 ± 11.03, experiencing an acute\u0000manic episode and receiving valproate sodium treatment for one week were randomly assigned to\u0000either the melatonin group or the placebo group. Both melatonin and a matched placebo were initiated\u0000at a dosage of 3 mg/day at bedtime for the first week and increased to 6 mg/day for the subsequent\u0000three weeks. The primary efficacy endpoint focused on evaluating the severity of manic symptoms\u0000using the Young Mania Rating Scale (YMRS) at enrollment and at weeks 1, 2, and 4 postinterventions.\u0000Additionally, as a secondary efficacy endpoint, the change in insomnia severity was\u0000assessed at the end of the study period using the Insomnia Severity Index (ISI) questionnaire.\u0000\u0000\u0000\u0000Analyses were conducted on an Intention-to-Treat (ITT) analysis dataset. Despite a significant\u0000decrease in mean Young Mania Rating Scale (YMRS) scores over the four-week study period in\u0000both treatment groups, melatonin exhibited a notably higher improvement in manic symptoms compared\u0000to the placebo (p-value ≤ 0.001). By the end of week 4, patients receiving a placebo demonstrated\u0000a mean ± SD decrease in YMRS scores of -17.3 ± 4.75, while those treated with melatonin\u0000experienced a more substantial reduction, with a mean ± SD of -21.06 ± 5.92 (p-value = 0.012). The\u0000proportion of responders, defined as patients with a ≥ 50% reduction in YMRS total score, and remitters,\u0000defined as those with an endpoint YMRS score ≤12, was also significantly higher in the melatonin-\u0000treated group compared to the placebo group. Furthermore, at the study endpoint, the melatonin\u0000group experienced a greater reduction in the mean ISI score compared to the placebo group (11.51 ±\u00003.07 versus 8.97 ± 3.56; p-value < 0.001). Importantly, melatonin was well tolerated by the study\u0000patients at this dosage.\u0000\u0000\u0000\u0000In summary, our study findings provide support for the use of melatonin as an adjunctive\u0000therapy in the treatment of acute bipolar mania. The positive outcomes observed warrant further\u0000investigations to replicate and extend these findings, contributing to a more comprehensive understanding\u0000of melatonin's role in managing bipolar disorder during manic episodes\u0000","PeriodicalId":515404,"journal":{"name":"The Natural Products Journal","volume":"108 s418","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141377088","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Comprehensive Review of n-butylidenephthalide: The Potential\u0000Therapeutic Effect and Possibility for Targeted Therapy","authors":"Swati, Kangkan Sarma, Ruchi Bhardwaj, laxita Chauhan, Ritika Sharma, Payel Mal","doi":"10.2174/0122103155287645240528114302","DOIUrl":"https://doi.org/10.2174/0122103155287645240528114302","url":null,"abstract":"\u0000\u0000n-Butylidene phthalide (N-BP) is a natural derivative obtained from the chloroform extract\u0000of Angelica Sinensis. In conventional medicine, it treats different ailments. Various pharmacological\u0000properties are associated with it, including anticancer, anti-inflammatory, and neuroprotective\u0000properties. Based on its reported pharmacokinetic profile, n-BP has low oral bioavailability and is\u0000rapidly absorbed and eliminated from the body. The compound has diverse pharmacological effects\u0000with lower stability, bioavailability, rapid absorption, and elimination. Furthermore, a targeted drug\u0000delivery system using a nanocarrier can improve pharmacokinetic-molecular profiling, specificity,\u0000efficacy, personal approach, and drug resistance. This review summarizes and emphasizes the pharmacokinetics,\u0000and pharmacology of n-butylidene phthalide, and the molecular targeting approach to\u0000treat cancer, inflammation, Parkinsonism, excitotoxicity, and Alzheimer’s.\u0000","PeriodicalId":515404,"journal":{"name":"The Natural Products Journal","volume":"24 38","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141380119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Advancements in Chemical Proteomics for Target Identification of Natural\u0000Products in Live Cells","authors":"Abid H. Banday, Insha Ashraf, Mudasir Bashir, Aariya Yousuf, Basit Qayoom, Mysar Ahmad Bhat, Saima Nabi, Saima Maqbool, Muzaffar A. Lone","doi":"10.2174/0122103155290163240528065607","DOIUrl":"https://doi.org/10.2174/0122103155290163240528065607","url":null,"abstract":"\u0000\u0000Natural products have evolved to interact with specific protein targets within cells, making\u0000them valuable for various biological functions. Chemical proteomics, specifically the use of covalently\u0000linked probes in live cells, allows for the identification of protein-binding partners or targets of\u0000small molecules. Recent advancements in target identification of natural products have utilized affinity-\u0000based probes and photo-affinity labeling techniques, enabling the capture of potential cellular\u0000targets even when the interaction is reversible. This knowledge can aid in understanding molecular\u0000pathways and developing new therapeutics for diseases lacking treatment options. Several methods,\u0000including DARTS, SPROX, CETSA, TPP, and bioinformatics-based analysis, are employed for target\u0000identification of label-free natural products. Chemical probe design and synthesis are tailored to\u0000screen targets of molecules with diverse structures. The comprehensive proteomic analysis reported\u0000herein aims to investigate target sites contributing to biologically significant effects, considering both\u0000desirable phenotypes and potential toxicity or side effects.\u0000","PeriodicalId":515404,"journal":{"name":"The Natural Products Journal","volume":"103 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141377986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Novel Approaches for the Extraction and Identification of Phytoconstituents\u0000from Herbs and Spices","authors":"Preet Amol Singh, Shiva Tushir, Subhajit Hazra, Sukhvinder Singh Purewal, Gaurav Agarwal","doi":"10.2174/0122103155293641240417072907","DOIUrl":"https://doi.org/10.2174/0122103155293641240417072907","url":null,"abstract":"\u0000\u0000An important determinant of population health is the caliber and quality of food that can\u0000directly affect the health of the population. Herbs and spices are now the primary ingredients in the\u0000global food and nutraceutical industry. Traditional methods for extraction of active metabolites of\u0000herbs and spices may lead to lowered extraction efficiency due to high solvent consumption and a\u0000longer extraction period. These issues can be resolved by the use of novel green and sustainable extraction\u0000techniques. The present paper aims to discuss innovative extraction and identification techniques\u0000for herbs and spices. Microwave-aided extraction (MAE), ultrasound-assisted extraction\u0000(UAE), supercritical fluid extraction (SFE), DNA barcoding, THz-S, e-nose, near-infrared (NIR)\u0000spectroscopy, hyperspectral imaging, Raman spectroscopy possess environment-friendly instrumentations,\u0000make lesser use of chemicals, and reduce the consumption of solvent. The use of cuttingedge\u0000technology in place of outdated ones can improve product quality and help the general public\u0000maintain high levels of health.\u0000","PeriodicalId":515404,"journal":{"name":"The Natural Products Journal","volume":"70 3‐4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141376465","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}