{"title":"Intestinal ultrasound in primary intestinal lymphangiectasia (Waldmann's disease): a PRISMA-ScR scoping review with an illustrative adult case.","authors":"Luisa Bertin, Miriana Zanconato, Camilla Cavagna, Brigida Barberio, Cristina Caranfil, Cristina Bezzio, Patrizia Burra, Edoardo Vincenzo Savarino, Fabiana Zingone","doi":"10.1007/s40477-026-01181-5","DOIUrl":"https://doi.org/10.1007/s40477-026-01181-5","url":null,"abstract":"<p><p>Primary intestinal lymphangiectasia (PIL; Waldmann's disease, ORPHA 90362) is a rare protein-losing enteropathy in which dilated intestinal lacteals leak chyle into the gut lumen. Cross-sectional imaging and lymphoscintigraphy have historically dominated assessment, while transabdominal B-mode intestinal ultrasound (IUS)-a cornerstone modality for inflammatory bowel disease-has remained almost unmapped in PIL. We conducted a PRISMA-ScR scoping review (Open Science Framework preregistration gfbc9) of all primary studies reporting transabdominal B-mode IUS in PIL, searching three bibliographic platforms (PubMed/MEDLINE, Ovid Multifile, Scopus) supplemented by forward and backward citation chasing. Studies using only extra-intestinal ultrasound, endoscopic ultrasound, those describing secondary lymphangiectasia or focal lymphangioma, and those using ultrasound only as procedural guidance for lymphangiography were excluded at full-text stage. Fifteen primary studies, published 1986-2026 across thirteen countries, met eligibility (nine paediatric, six adult). All fifteen reported per-patient B-mode IUS findings extractable for synthesis. A consistent sonographic signature emerged: diffuse, regular, slightly hypoechoic small-bowel-wall thickening with preserved five-layer stratification and prominent valvulae conniventes; dilated fluid-filled loops with reduced peristalsis; oedematous mesentery, variable ascites; and characteristically absent mesenteric lymphadenopathy (with two notable exceptions framed only as a research hypothesis). Diagnostic accuracy as a screening tool has been evaluated only in one study (n = 20: accuracy 80%, 95% CI 56.3-94.3%). We illustrate this signature in a 42-year-old woman with Hennekam syndrome and report quantitative B-mode IUS values as anecdotal single-observation-single sonographer, single device, single fasted time-point, mid-jejunal segment to motivate, prospective standardisation.</p>","PeriodicalId":51528,"journal":{"name":"Journal of Ultrasound","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2026-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148622444","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Carlos López-de-Celis, Sergio Borrella-Andrés, Miguel Malo-Urriés, Isabel Albarova-Corral, Vanessa González-Rueda, Jacobo Rodríguez-Sanz
{"title":"Impact of experience and specialization on accuracy and perceived performance of needling techniques in the cubital tunnel: a cadaveric study.","authors":"Carlos López-de-Celis, Sergio Borrella-Andrés, Miguel Malo-Urriés, Isabel Albarova-Corral, Vanessa González-Rueda, Jacobo Rodríguez-Sanz","doi":"10.1007/s40477-026-01192-2","DOIUrl":"https://doi.org/10.1007/s40477-026-01192-2","url":null,"abstract":"<p><strong>Background: </strong>Invasive needling procedures in physiotherapy can be performed using palpation or ultrasound guidance. While ultrasound offers greater precision and safety, the influence of healthcare professional experience and specialization in this field on performance has not yet been fully explored. The aim was to compare the accuracy, efficiency, safety, and perceived workload of ultrasound-guided versus palpation-guided needling procedures among physiotherapists with different levels of experience and specialization.</p><p><strong>Methods: </strong>Twenty-seven physiotherapists (students, non-specialized and specialized physiotherapists) performed 20 needling tasks each, on cadaveric specimens, targeting the ulnar nerve in the cubital tunnel. Procedures were conducted under two guidance conditions (ultrasound vs. palpation) and two handling modalities (with or without handpiece). Performance metrics (e.g., distance to target, structures affected) and subjective workload were recorded.</p><p><strong>Results: </strong>Specialized physiotherapists demonstrated significantly greater precision, efficiency, and safety than the other groups (p < 0.001). Students and non-specialized professionals had similar performance, particularly in terms of precision and control. Subjective workload was lower in specialists, especially under ultrasound guidance.</p><p><strong>Conclusion: </strong>Ultrasound guidance improves needling outcomes, especially when performed by trained specialists. General clinical experience without focused ultrasound training may be insufficient to ensure optimal procedural control. These findings support the integration of ultrasound training in advanced physiotherapy programs and the need to seek strategies that enhance learning.</p>","PeriodicalId":51528,"journal":{"name":"Journal of Ultrasound","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2026-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148622416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Intestinal intussusception with a tadpole-shaped low-grade appendiceal mucinous neoplasm as the leading point: a case report.","authors":"Shingo Shioya, Koichiro Shigeta","doi":"10.1007/s40477-026-01196-y","DOIUrl":"https://doi.org/10.1007/s40477-026-01196-y","url":null,"abstract":"<p><p>A tadpole-shaped appendix has been described as a characteristic morphology of appendiceal mucinous lesions, but its clinical and ultrasonographic significance has not been fully clarified. We report a case of low-grade appendiceal mucinous neoplasm (LAMN) in which a tadpole-shaped appendiceal lesion acted as the leading point of extensive intestinal intussusception. A woman in her 60s presented with abdominal pain and difficulty with defecation. Abdominal ultrasonography demonstrated extensive intestinal intussusception extending to the transverse colon. At the leading point, the long-axis view showed a tadpole-shaped configuration composed of a spherical cystic dilated portion and a contiguous tubular structure. Dynamic observation suggested that these findings represented a single continuous appendiceal structure rather than separate cystic lesions. The short-axis view of the same structure showed a multilayered concentric ring appearance. Surgical and histopathologic examination established the diagnosis of appendiceal intussusception associated with LAMN, with secondary intestinal intussusception. Although prior or serial imaging was not available to directly demonstrate temporal progression from appendiceal to intestinal intussusception, previous reports have described appendiceal mucinous lesions with tadpole-shaped or cup-and-ball morphology as the leading point of intussusception. Therefore, when this morphology is identified on ultrasonography, careful assessment for appendiceal or intestinal intussusception is warranted. Recognition of this morphology and its continuity on ultrasonography may serve as a practical diagnostic clue and contribute to preoperative diagnosis and appropriate surgical management.</p>","PeriodicalId":51528,"journal":{"name":"Journal of Ultrasound","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2026-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148609979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Ultrasonographic assessment of an esophageal foreign body with emphasis on material properties: a case report.","authors":"Riu Homma, Hirota Saito","doi":"10.1007/s40477-026-01188-y","DOIUrl":"https://doi.org/10.1007/s40477-026-01188-y","url":null,"abstract":"<p><p>A teenage male with severe motor and intellectual disabilities was referred for evaluation of an esophageal mass detected on computed tomography(CT). Because the patient was nonverbal, the cause of the lesion and the possibility of foreign body ingestion were unclear. CT demonstrated a spherical lesion with fat-equivalent attenuation in the upper esophagus, but material composition and procedural safety were not determined. Ultrasonography, performed for further assessment, revealed a well-circumscribed spherical intraluminal lesion without internal vascularity. Comparative ultrasonographic evaluation using spherical objects of similar size showed that metallic and glass materials produced characteristic reverberation artifacts that were absent in the lesion, suggesting a non-metallic composition. This information supported clinical decision-making regarding removal strategy. The foreign body was successfully removed using a combined endoscopic and surgical approach. This case highlights the role of ultrasonography in evaluating esophageal foreign bodies and estimating material properties when other imaging modalities are limited.</p>","PeriodicalId":51528,"journal":{"name":"Journal of Ultrasound","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2026-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148594365","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Renal resistive ındex in augmented renal clearance: limitations of static assessment and the case for a dynamic approach.","authors":"Hüsnü Tokgöz, Özlem Tokgöz","doi":"10.1007/s40477-026-01190-4","DOIUrl":"https://doi.org/10.1007/s40477-026-01190-4","url":null,"abstract":"","PeriodicalId":51528,"journal":{"name":"Journal of Ultrasound","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2026-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148594374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Luigi Vetrugno, Pasquale De Vico, Domenico Junior Brunetti, Valentina Bellini, Cristian Deana, Elena Giovanna Bignami, Daniele Guerino Biasucci
{"title":"Beyond drug discontinuation and prolonged fasting: gastric ultrasound as a third option for patients taking GLP-1 receptor agonists.","authors":"Luigi Vetrugno, Pasquale De Vico, Domenico Junior Brunetti, Valentina Bellini, Cristian Deana, Elena Giovanna Bignami, Daniele Guerino Biasucci","doi":"10.1007/s40477-026-01198-w","DOIUrl":"https://doi.org/10.1007/s40477-026-01198-w","url":null,"abstract":"","PeriodicalId":51528,"journal":{"name":"Journal of Ultrasound","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2026-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148594328","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Contrast-enhanced ultrasound findings in GLUT1-negative congenital hemangiomas: a descriptive case series of superficial and hepatic lesions.","authors":"Dolores Ferrara, Enrico Perre, Salvatore Miressi, Filomena Barbato, Massimo Zeccolini, Francesco Esposito","doi":"10.1007/s40477-026-01189-x","DOIUrl":"https://doi.org/10.1007/s40477-026-01189-x","url":null,"abstract":"<p><p>Congenital hemangiomas (CHs) are fully developed at birth, GLUT1-negative vascular tumors that share biological features with isolated congenital hepatic hemangiomas (HHs), but CEUS patterns of superficial CHs are poorly defined. This retrospective case series qualitatively describes CEUS microvascular enhancement in superficial CHs and isolated focal HHs to explore cross-site perfusion similarities. Six children were included: four superficial CHs (right lower limb RICH, left cheek, abdomen, chest) and two isolated HHs (segment VI), studied with LOGIQ E10 and sulfur hexafluoride microbubbles using low mechanical index imaging. All lesions showed early peripheral or centripetal enhancement (6-14 s), progressive globular filling (complete by 70-150 s), and late-phase (> 270 s) signal reduction; in superficial lesions, late decrease could not be defined as washout. Superficial CHs and isolated HHs demonstrated qualitatively comparable CEUS dynamics, suggesting a potential role of CEUS in non-invasive characterization of congenital vascular tumors.</p>","PeriodicalId":51528,"journal":{"name":"Journal of Ultrasound","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2026-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148594333","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mohamed Abdulla, Hakima Al-Hashimi, Neale Kalis, James Blackwell
{"title":"Discordant 2D shear wave elastography values in post-Fontan patients with ascites: a potential interpretive pitfall.","authors":"Mohamed Abdulla, Hakima Al-Hashimi, Neale Kalis, James Blackwell","doi":"10.1007/s40477-026-01204-1","DOIUrl":"https://doi.org/10.1007/s40477-026-01204-1","url":null,"abstract":"<p><p>Fontan-associated liver disease (FALD) may progress to portal hypertension, ascites, and nodular liver remodelling. Two-dimensional shear wave elastography (2D-SWE) can be performed in patients with ascites, but its reliability in this setting remains uncertain. We report two post-Fontan patients with ascites and nodular liver morphology on B-mode ultrasound who showed markedly discordant liver stiffness values. The pediatric patient had high stiffness (median 24.25 kPa; IQR/median 3.4%), whereas the adult patient with clinical decompensation, large-volume ascites, and pleural effusion had unexpectedly low stiffness (median 9.55 kPa; IQR/median 23.6%). These cases suggest that substantial ascites may contribute to misleading 2D-SWE measurements. In post-Fontan patients, elastography should be interpreted alongside acquisition quality metrics, morphology, and clinical findings.</p>","PeriodicalId":51528,"journal":{"name":"Journal of Ultrasound","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2026-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148585974","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Guido Marchi, Carmine Salerni, Jacopo Cefalo, Gian Piero Bandelli, Martina Ferioli, Matteo Ciracì, Piero Candoli, Michele Mondoni
{"title":"Thoracic ultrasound elastography in pleural and subpleural diseases: a narrative review.","authors":"Guido Marchi, Carmine Salerni, Jacopo Cefalo, Gian Piero Bandelli, Martina Ferioli, Matteo Ciracì, Piero Candoli, Michele Mondoni","doi":"10.1007/s40477-026-01183-3","DOIUrl":"https://doi.org/10.1007/s40477-026-01183-3","url":null,"abstract":"<p><p>Ultrasound elastography measures tissue stiffness and has demonstrated clinical utility across multiple medical specialties. In respiratory medicine, its application is increasingly explored for pleural and subpleural lesions, pleural effusions, and pneumothorax. This narrative review examines current evidence for thoracic ultrasound elastography, highlighting potential benefits and key limitations. Several studies suggest that elastography can differentiate malignant from benign pleural lesions and show superior sensitivity for elastography-guided versus traditional ultrasound-guided pleural biopsy. However, significant challenges hinder clinical implementation: lack of standardised protocols, variability across ultrasound systems, operator dependency, and limited multicentre validation. The \"elasto-lung point\" sign has been described as potentially useful for pneumothorax detection, but its incremental value beyond conventional ultrasound remains uncertain and requires further investigation. Elastography has also been preliminarily studied for non-expandable lung detection, although current evidence suggests that M-mode ultrasound may perform better. Integration with artificial intelligence holds promise to enhance future diagnostic capabilities. Overall, thoracic elastography represents an innovative approach that requires substantial validation before routine clinical use can be recommended. Future priorities include protocol standardisation, rigorous multicentre studies, and demonstration of impact on patient outcomes.</p>","PeriodicalId":51528,"journal":{"name":"Journal of Ultrasound","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2026-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148581001","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Filippo Cotellessa, Salvatore Massimo Stella, Andrea Boccatonda, Giuliana Roselli, Marco Becciolini
{"title":"Myofibroma of the distal biceps brachii tendon: imaging findings of a rare entity.","authors":"Filippo Cotellessa, Salvatore Massimo Stella, Andrea Boccatonda, Giuliana Roselli, Marco Becciolini","doi":"10.1007/s40477-026-01174-4","DOIUrl":"https://doi.org/10.1007/s40477-026-01174-4","url":null,"abstract":"<p><p>The case highlights the complementary role of dynamic ultrasound and magnetic resonance in an atypical cause of anterior elbow pain. Ultrasound revealed a hypoechoic mass adjacent to the distal biceps tendon and enabled assessment of its close relationship with the tendon by demonstrating movement synchronous with tendon excursion. Although establishing the final diagnosis was challenging, it was ultimately achieved through histological examination.</p>","PeriodicalId":51528,"journal":{"name":"Journal of Ultrasound","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2026-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148426221","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}