Journal of Ultrasound最新文献

{"title":"Ectopia cordis with multiple congenital malformations: rare but real.","authors":"Shruti Thakur, Sumala Kapila, Charu Smita Thakur, Narender Thakur","doi":"10.1007/s40477-025-01023-w","DOIUrl":"10.1007/s40477-025-01023-w","url":null,"abstract":"<p><p>Ectopia cordis is a rare congenital defect where in a portion or the entire heart is mispositioned outside the thoracic cage. The exact cause is not clear. It may present as an isolated anomaly or may be associated with other congenital malformations. Once detected on antenatal sonography, a detailed anatomical and high-quality cardiac scan of the fetus is warranted. The prognosis is poor, and most infants are stillborn or die in early neonatal life. Early diagnosis is essential as it has consequences on the method of termination of pregnancy and its safety profile. We report a case of ectopia cordis with associated multiple congenital malformations that included ventriculomegaly, omphalocele with herniation of liver and intestines, and bilateral clubfeet. In view of the scarcity of data regarding this unusual condition and its association with multiple anatomic defects and limited clinical experience with its management, medical termination of pregnancy is desirable.</p>","PeriodicalId":51528,"journal":{"name":"Journal of Ultrasound","volume":" ","pages":"531-535"},"PeriodicalIF":1.3,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12145345/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144021303","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multiparametric ultrasound in acute scrotum: a comprehensive review with special emphasis on contrast-enhanced ultrasound.","authors":"Maria Laura Schillirò, Valeria Lonardo, Francesca Iacobellis, Martina Caruso, Costanza Camillo, Chiara D'Errico, Francesco Verde, Francesco Muto, Giuseppina Dell'Aversano Orabona, Chiara Rinaldo, Dario Grimaldi, Vittorio Sabatino, Enrico Scarano, Maurizio Carrino, Luigi Pucci, Vito Cantisani, Gianfranco Vallone, Marco Di Serafino","doi":"10.1007/s40477-025-01017-8","DOIUrl":"10.1007/s40477-025-01017-8","url":null,"abstract":"<p><p>Acute scrotum poses diagnostic challenges due to its diverse etiology and potential severity. Multiparametric ultrasound has proven to be a fundamental and valuable imaging modality in this context, improving early-phase sensitivity through various techniques, including B-Mode, color Doppler, power Doppler, pulsed Doppler, microflow studies, and elastography. In this context, Contrast-Enhanced Ultrasound (CEUS) emerges as a rapid, safe, and valuable tool in enhancing diagnostic accuracy and therapeutic decisions for acute scrotal conditions. This study involves a detailed analysis of various ultrasound imaging techniques and investigates the optimal circumstances and methods for employing CEUS in emergency situations to improve diagnostic accuracy and therapeutic decisions. Multiparametric ultrasound plays a crucial role in diagnosing various pathologies, including testicular torsion, appendage torsion, inflammation, ischemia/infarction, and trauma. CEUS provides real-time assessment of vascular perfusion, aiding in early diagnosis and accurate characterization of scrotal pathologies and significantly reducing the need for unnecessary surgical interventions, especially in trauma cases. Its role in differentiating between various pathologies and guiding therapeutic decisions underscores its importance in clinical practice, contributing significantly to improve patient outcomes.</p>","PeriodicalId":51528,"journal":{"name":"Journal of Ultrasound","volume":" ","pages":"305-321"},"PeriodicalIF":1.3,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12145392/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144026168","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Contrast-enhanced ultrasonography (CEUS) in the management of pediatric renal injuries: where are we now?","authors":"Dacia Di Renzo, Cristina Gentile, Antonello Persico, Giuseppe Lauriti, Francesco Chiarelli, Gabriele Lisi","doi":"10.1007/s40477-025-01011-0","DOIUrl":"10.1007/s40477-025-01011-0","url":null,"abstract":"<p><strong>Purpose: </strong>Experience with CEUS in management of kidney post-traumatic injuries is limited, especially in pediatric age. This paper aimed to identify: clinical settings in which CEUS could be used as first diagnostic tool, skipping CT; CEUS ability to detect complications during non-operative management (NOM); and CEUS role in patients with collecting system injuries.</p><p><strong>Methods: </strong>Patients with renal trauma admitted between 2003 and 2023 were enrolled in a retrospective study. At T0, CT was performed in case of high-energy trauma, CT or CEUS in case of low-energy or/and localized trauma. CEUS was used during follow up (FU) in case of suspected complications and to follow healing of the lesions and urinomas.</p><p><strong>Results: </strong>Among 22 patients included, at T0 20/22 performed CT, 1/22 CEUS and 1/22 baseline US. During NOM CEUS was necessary: in early FU to rule out complications in 3/22 (1 anemization and 2 hematuria); in middle FU in 14/22 to authorize mobilization/discharge and monitor urinomas; in outpatient setting in 2/22, to authorize return to sport activities. Overall, a collecting system injury was detected in 6 patients by CT and in 1 by CEUS. In 3/7 a perirenal urinoma developed. All were monitored with CEUS or baseline US.</p><p><strong>Conclusions: </strong>CEUS is useful as first imaging study in low-energy and localized trauma, but confidence with CEUS is still to be improved and spread, to replace CT in selected cases. CEUS is valuable for detecting complications, avoiding repeat CT in most of cases. In expert hands CEUS can identify and monitor leakage indirectly.</p>","PeriodicalId":51528,"journal":{"name":"Journal of Ultrasound","volume":" ","pages":"429-436"},"PeriodicalIF":1.3,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12145329/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143694401","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Longitudinal assessment of liver stiffness using ARFI technique does not support increased risk of fibrosis in rheumatoid arthritis patients on methotrexate.","authors":"Arne Schäfer, Magdolna Szilvia Kovacs, Anna Eder, Axel Nigg, Martin Feuchtenberger","doi":"10.1007/s40477-023-00843-y","DOIUrl":"10.1007/s40477-023-00843-y","url":null,"abstract":"<p><strong>Aims: </strong>To assess the liver stiffness in patients with rheumatoid arthritis treated with methotrexate monotherapy using non-invasive, ultrasound-based elastography (acoustic radiation force impulse (ARFI) imaging) in a longitudinal approach.</p><p><strong>Methods: </strong>In total, 23 MTX-naive patients were longitudinally assessed using acoustic radiation force impulse (ARFI) imaging. Baseline assessments were carried out between July 2018 and April 2019, and the follow-up evaluations took place after an average of 2.6 years. The main outcome variable was the mean shear wave velocity as measured by the ARFI method. It was calculated from 10 valid ARFI measurements for each patient. Inferential statistical analyses (within-group comparisons) were performed using t-tests for dependent samples or suitable nonparametric procedures.</p><p><strong>Results: </strong>The main finding was that observed ARFI shear wave velocities did not increase during the observation period. In fact, this parameter decreased over time from 1.07 m/s (SD = 0.23) at baseline without MTX exposure to 0.97 m/s (SD = 0.16) at follow-up after a mean of 2.6 years (P = 0.013). Moreover, the magnitude of the change in shear wave velocity could not be predicted by indicators of inflammation or disease activity, BMI, age, sex or NSAR intake (corresponding regression analysis: corrected R² = 0.344; P = 0.296).</p><p><strong>Conclusions: </strong>No increased risk of liver fibrosis was found in RA patients treated with MTX monotherapy during observation period.</p>","PeriodicalId":51528,"journal":{"name":"Journal of Ultrasound","volume":" ","pages":"323-329"},"PeriodicalIF":1.3,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12145398/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139473077","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Wrist and elbow fracture detection and segmentation by artificial intelligence using point-of-care ultrasound.","authors":"Yuyue Zhou, Jessica Knight, Fatima Alves-Pereira, Christopher Keen, Abhilash Rakkunedeth Hareendranathan, Jacob L Jaremko","doi":"10.1007/s40477-025-01019-6","DOIUrl":"10.1007/s40477-025-01019-6","url":null,"abstract":"<p><strong>Purpose: </strong>Distal radius (wrist) and supracondylar (elbow) fractures are common in children presenting to Pediatric Emergency Departments (EDs). These fractures are treated conservatively or surgically depending on deformity severity. Radiographs are typically used for diagnosis but can increase wait times due to the need for radiation-safe rooms. Ultrasound (US) offers a radiation-free, faster alternative that can be performed at triage, but its noisy images are challenging to interpret.</p><p><strong>Methods: </strong>We developed an artificial intelligence (AI) technique for the automatic diagnosis of fractures at the wrist and elbow. While most AI for diagnosis focuses on classification results only, we applied a more explainable pipeline that used US bony region segmentation from a CNN as the basis of fracture detection. Our approach was validated on 3,822 wrist US images and 1487 elbow US images. We compared the fracture detection results from classification models and multi-channel segmentation models.</p><p><strong>Results: </strong>Combining the segmentation results with the original images showed superior performance in fracture detection at the individual patient level, achieving an accuracy of 0.889 and 0.750, sensitivity of 0.818 and 1.000, and specificity of 1.000 and 0.714 on the wrist and elbow dataset respectively. Besides, the multi-channel U-Net architecture effectively detected bony fracture regions in wrist US images.</p><p><strong>Conclusion: </strong>These findings demonstrate that AI models can enable reliable, automatic wrist and elbow fracture detection in pediatric EDs, potentially reducing wait times and optimizing medical resource use.</p>","PeriodicalId":51528,"journal":{"name":"Journal of Ultrasound","volume":" ","pages":"465-473"},"PeriodicalIF":1.3,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12145391/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144016912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of ultrasound derived fat fraction for metabolic associated fatty liver disease in obese patients with polycystic ovary syndrome.","authors":"LingZhi Meng, Hui Yang, YiXuan Hu, YuShan Jiang, ZongLi Yang","doi":"10.1007/s40477-024-00982-w","DOIUrl":"10.1007/s40477-024-00982-w","url":null,"abstract":"<p><strong>Objective: </strong>To explore the application of ultrasound derived fat fraction (UDFF) in evaluating metabolic associated fatty liver disease in obese polycystic ovary syndrome.</p><p><strong>Method: </strong>This study included 124 obese PCOS patients and 106 age and body mass index (BMI) matched non PCOS control group women. The two groups of data were compared to determine the prevalence of metabolic associated fatty liver disease (MAFLD) in PCOS obese patients. The 124 obese PCOS patients were divided into MAFLD group (n = 64) and non MAFLD group (n = 60). Using ROC curve analysis to evaluate the diagnostic performance of UDFF and SWV values for MAFLD. The MAFLD group was divided into mild group (n = 16), moderate group (n = 24), and severe group (n = 24). Use Spearman correlation method to analyze the relationship between UDFF value, SWV value and the severity of MAFLD.</p><p><strong>Result: </strong>MAFLD was more common in the obese PCOS group than in the control group (51.61 vs 27.36%) (χ² = 13.9583, P = 0.00019). The UDFF of obese PCOS patients was higher than those of the control group, while SWV was lower than those of the control group. ROC analysis showed that the AUC of UDFF for diagnosing MAFLD was 0.935, with sensitivity, specificity, and cut-off values of 92.2, 85.0, and 4.5%, respectively. UDFF was positively correlated with the severity of MAFLD (r = 0.603, P < 0.01). The AUC of SWE for diagnosing MAFLD was 0.728, with sensitivity, specificity, and cut-off values of 51.6, 93.3%, and 1.015 m/s, respectively. SWV was negatively correlated with the severity of MAFLD (r = - 0.551, P < 0.01).</p><p><strong>Conclusion: </strong>The prevalence of MAFLD is significantly higher in obese PCOS patients, and UDFF technology can detect and quantitatively analyze liver fat infiltration in obese PCOS patients early. At the same time, auto-pSWE also has diagnostic significance for the progression of liver disease.</p>","PeriodicalId":51528,"journal":{"name":"Journal of Ultrasound","volume":" ","pages":"379-387"},"PeriodicalIF":1.3,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12145385/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143191078","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multiparametric ultrasound for non-invasive evaluation of kidney graft function.","authors":"Maria Irene Bellini, Sergio Angeletti, Daniele Fresilli, Mattia Di Segni, Gian Marco Lo Conte, Raponi Flavia, Manuela Garofalo, Renzo Pretagostini, Corrado De Vito, Patrizia Pacini, Vito D'Andrea, Angelo Barbato, Francesco M Drudi, Marcello Caratozzolo, Vito Cantisani","doi":"10.1007/s40477-025-00989-x","DOIUrl":"10.1007/s40477-025-00989-x","url":null,"abstract":"<p><strong>Background: </strong>Renal transplant (RT) remains the optimal treatment for end-stage renal disease and early complications might be detected in the postoperative period to improve long-term outcomes. To this regard, contrast enhanced ultrasound (CEUS) could be utilized to evaluate RT functional recovery and potentially detect acute rejection (AR) and/or renal ischemia signs.</p><p><strong>Materials and methods: </strong>Observational study of 107 consecutive patients waitlisted for RT. Participants underwent conventional ultrasound (CUS) and color-doppler-ultrasound (CDUS) to evaluate resistive index of segmental and interlobar arteries and quantitative CEUS techniques recording the following perfusion parameters: peak intensity (PI-c), rising time (RT-c), area under (AUC-c) the time intensity curve (TIC), time to peak (TTP-c) and mean transit time (MTT-c).</p><p><strong>Results: </strong>CEUS parameters sensibility and specificity to predict AR in the early post-operative period resulted in: 90% and 69% for PI-c, 95% and 64% for RT-c, 85% and 65% for AUC-c. The overall diagnostic performance of these three CEUS parameters in comparison to the same in CUS and CDUS resulted in a sensitivity and specificity of 95% and 49%, versus 85% and 46%, respectively, therefore CEUS examination with the analysis of PI-c, RT-c and AUC-c values increases the diagnostic sensitivity in predicting AR by approximately 15-20% compared to CDUS and by 30-40% compared to CUS.</p><p><strong>Conclusion: </strong>CEUS could be routinely included in RT follow-up, as it shows to be a non-invasive helpful diagnostic tool for early detection of renal graft complications, selecting patients eventually in need of further confirmation.</p>","PeriodicalId":51528,"journal":{"name":"Journal of Ultrasound","volume":" ","pages":"269-280"},"PeriodicalIF":1.3,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12145335/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143781586","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Biceps brachii elastography in well-trained men post eccentric exercise-induced muscle damage.","authors":"Maria Clara Albuquerque Brandão, Lino de Azevedo Matias, Thiago Torres da Matta, Liliam Fernandes de Oliveira","doi":"10.1007/s40477-024-00886-9","DOIUrl":"10.1007/s40477-024-00886-9","url":null,"abstract":"<p><strong>Purpose: </strong>Recent advancements in elastography techniques, specifically supersonic shearwave elastography (SWE), have enabled non-invasive assessment of muscle stiffness. However, there is limited research on the immediate and short-term effects of eccentric exercise-induced muscle damage (EIMD) in well-trained individuals. This study aimed to follow up on the effects of eccentric training on the biceps brachialis stiffness by supersonic shearwave imaging (SSI) as well as the soreness and elbow flexion maximal voluntary isometric contraction (MVIC), immediately post-intervention, at 10 min, 48 h, and 96 h in well-trained men.</p><p><strong>Methods: </strong>Thirteen well-trained males participated in the study. Baseline measurements of elastography images, MVIC of the elbow flexors, and muscle soreness were obtained. The participants performed an eccentric exercise protocol (4 sets X 10 repetitions) on the dynamometer isokinetic and elastography measurements were repeated immediately post-exercise, at 10 min, 48 h, and 96 h.</p><p><strong>Results: </strong>Significant reductions in stiffness (measured by shear modulus (µ)) were observed immediately and at 10 min post-exercise. MVIC exhibited significant reductions immediately after, 10 min, and 48 h compared to baseline measurements. Muscle soreness peaked at 48 h, persisting until 96 h.</p><p><strong>Conclusions: </strong>The BB stiffness and MVIC reduction immediately post-eccentric exercise in well-trained men, suggest the potential involvement of mechanical stress and sarcomere rupture. Trained individuals may exhibit a distinct response to EIMD compared to untrained individuals, highlighting the applicability of elastography in monitoring acute biomechanical changes following high-intensity exercise.</p>","PeriodicalId":51528,"journal":{"name":"Journal of Ultrasound","volume":" ","pages":"331-338"},"PeriodicalIF":1.3,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12145348/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140319868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The association between integrating echocardiography use in the management of septic shock patients and outcomes in the intensive care unit: a systematic review and meta-analysis.","authors":"Keith Killu, Cecilia Patino-Sutton, Lynn Kysh, Richard Castriotta, John Oropello, Luis Huerta, Dominic Engracia, Karim Merchant, Choo Phei Wee, Victoria Kristence Cortessis","doi":"10.1007/s40477-024-00958-w","DOIUrl":"10.1007/s40477-024-00958-w","url":null,"abstract":"<p><strong>Objectives: </strong>Septic shock in critically ill patients can increases morbidity and mortality. We aimed to study the effect on outcomes when integrating point of care (POC) echocardiography in the management of septic shock patients in the Intensive Care Unit (ICU) who are being treated according to the Surviving Sepsis Campaign (SSC) guidelines.</p><p><strong>Methods: </strong>An electronic search of MEDLINE through PubMed, clinical trials.gov and google scholar was conducted for the period from January 1990-January 2024 to identify studies of septic shock adult and pediatric patients in the ICU managed according to SSC guidelines with or without POC echocardiography. Three reviewers extracted data independent of each other. Cochrane collaboration tool was used for bias assessment. Random effect meta-analysis used to pool data.</p><p><strong>Results: </strong>A total of 1701 articles identified. Seven studies included in the final report with a total of 3885 patients. POC echocardiography guided septic shock management was associated with lower in-hospital and 28-day mortality (sOR = 0.82 [95%CI: 0.71-0.95], p = 0.01), more frequent initiation of inotropic support (sOR = 2.42 [95%CI 1.92-3.03], p < 0.0001) and shorter time to achieve lactate clearance (SMD = - 0.87 h [95%CI - 1.23 h to - 0.51 h], p < 0.0001). Summary estimates did not achieve significance for effect of POC echocardiography on 24-h fluid intake (SMD = - 2.11 ml [95%CI - 5.93 ml to 1.72 ml], p = 0.28) on mechanical ventilation-free days (SMD = 0.03 days [95%CI - 0.04 to 0.10], p = 0.94). Shock reversal time analysis was less meaningful due to the small number of studies reporting outcome.</p><p><strong>Conclusions: </strong>POC echocardiography guided management in septic shock patients in the ICU can lead to a decrease in mortality, increase in initiation of inotropic support, and a decrease in lactate clearance time. Larger cohort studies and data collection and analysis are needed for further understanding and optimizing standardization of protocols for POC echocardiography use in septic shock patients in the ICU.</p>","PeriodicalId":51528,"journal":{"name":"Journal of Ultrasound","volume":" ","pages":"281-294"},"PeriodicalIF":1.3,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12145375/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142480420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Can transabdominal shear wave elastography play a role in solving the dilemma of complex cystic and solid ovarian tumors by ultrasound?","authors":"Mennatallah Mohamed Hanafy, Mariam Rafaat, Hebatullah Mohammed Ibrahem, Fatma Mohamed Magdy Atta, Lamiaa Mohamed Bassam Hashem","doi":"10.1007/s40477-025-01027-6","DOIUrl":"10.1007/s40477-025-01027-6","url":null,"abstract":"<p><strong>Purpose: </strong>We aimed to assess the role of shear wave elastography in better characterizing complex cystic and solid ovarian tumors in correlation with other ultrasound features and histopathology.</p><p><strong>Materials and methods: </strong>The study included 40 patients with 40 unilateral complex cystic or solid ovarian lesions with a mean age of 43.2 ± 13.27 (mean ± SD). All patients were subjected to history taking, tumor markers assessment, ultrasound with Doppler assessment giving an ORADS score, and shear wave elastography assessment. (qualitatively and quantitatively). Correlation was done with the final histopathology.</p><p><strong>Results: </strong>According to the final histopathological results of the 40 lesions, 14 (35%) were benign, four were borderline (10%), and 22 (55%) were malignant. Ultrasound and Doppler assessments revealed a higher frequency of irregular margins and Doppler score 4 in borderline/malignant patients compared to benign patients. ORADS ultrasound scoring system of the examined lesions showed a statistically significantly higher frequency of ORADS 5 in the malignant group, with ORADS sensitivity, specificity, and Diagnostic accuracy of 96.2%, 57.1, and 82.5%, respectively. Elastographic color mapping scores and elastographic readings were higher in borderline/malignant patients compared to benign patients and it significantly correlated with the Doppler score, ORADS score, color mapping score, and tumor markers.</p><p><strong>Conclusion: </strong>The study detected significant associations between malignancy and higher tumor markers, marginal irregularity, higher Doppler, and higher ORADS scores. Shear wave elastography positively correlated with tumor markers, Doppler score, and ORADS score. This supports the utility of elastography in discriminating malignant from benign ovarian tumors.</p>","PeriodicalId":51528,"journal":{"name":"Journal of Ultrasound","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2025-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144192523","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}