{"title":"Oscillometric and Doppler techniques can provide continuous noninvasive blood pressure readings in cats and dogs: an instructional video.","authors":"Satoshi Haginoya, Elizabeth J Thomovsky","doi":"10.2460/javma.24.01.0039","DOIUrl":"https://doi.org/10.2460/javma.24.01.0039","url":null,"abstract":"OBJECTIVE\u0000To provide a video tutorial detailing how to perform continuous noninvasive blood pressure monitoring in dogs and cats.\u0000\u0000\u0000ANIMALS\u0000Any size dog or cat.\u0000\u0000\u0000METHODS\u0000To measure blood pressure noninvasively, a blood pressure cuff is selected on the basis of the circumference of the limb and placed at the level of the right atrium. For oscillometric blood pressure measurement, the cuff is connected to an oscillometric unit that will automatically inflate and deflate the cuff in order to measure the patient's blood pressure using an internal algorithm. For Doppler blood pressure measurement, a sphygmomanometer is used to manually inflate the pressure cuff 30 to 40 mm Hg above the point where the audible arterial sounds disappear. Then, the cuff is gradually deflated until the audible arterial sounds return; the pressure at the first sound is recorded as the blood pressure. To generate continuous readings, the oscillometric machine is set to measure blood pressure as often as every minute. Alternatively, the Doppler crystal is taped to the patient's leg to facilitate repeated cuff inflation/deflation and collection of blood pressure values as often as every minute.\u0000\u0000\u0000RESULTS\u0000Continuous blood pressure readings can be obtained by both the oscillometric and Doppler techniques.\u0000\u0000\u0000CLINICAL RELEVANCE\u0000Continuous blood pressure readings identify trends in a patient's cardiovascular status. The most reliable oscillometric blood pressure reading is the mean arterial pressure. Doppler blood pressure values are considered systolic in dogs. Doppler values in cats underestimate systolic and overestimate mean blood pressure.","PeriodicalId":514111,"journal":{"name":"Journal of the American Veterinary Medical Association","volume":"55 8","pages":"1"},"PeriodicalIF":0.0,"publicationDate":"2024-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140736909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Iris To, Allyson C Berent, C. Weisse, Anjile An, Brett Harling, Danny Sack, Robert Ciardullo, Dennis J Slade, Douglas A Palma, Antonia A DeJesus, A. Fischetti
{"title":"Preoperative parameters (signalment, digital radiography, urinalysis, urine microbiological culture) and novel algorithm improve prediction of canine urocystolith composition.","authors":"Iris To, Allyson C Berent, C. Weisse, Anjile An, Brett Harling, Danny Sack, Robert Ciardullo, Dennis J Slade, Douglas A Palma, Antonia A DeJesus, A. Fischetti","doi":"10.2460/javma.23.12.0686","DOIUrl":"https://doi.org/10.2460/javma.23.12.0686","url":null,"abstract":"OBJECTIVE\u0000To determine the accuracy of 4 preoperative parameters (signalment, urinalysis, urine microbiological culture, and digital radiography) in predicting urocystolith composition, compare accuracy between evaluators of varying clinical experience and a mobile application, and propose a novel algorithm to improve accuracy.\u0000\u0000\u0000ANIMALS\u0000175 client-owned dogs with quantitative analyses of urocystoliths between January 1, 2012, and July 31, 2020.\u0000\u0000\u0000METHODS\u0000Prospective experimental study. Canine urocystolith cases were randomly presented to 6 blinded \"stone evaluators\" (rotating interns, radiologists, internists) in 3 rounds, each separated by 2 weeks: case data alone, case data with a urolith teaching lecture, and case data with a novel algorithm. Case data were also entered into the Minnesota Urolith Center mobile application. Prediction accuracy was determined by comparison to quantitative laboratory stone analysis results.\u0000\u0000\u0000RESULTS\u0000Prediction accuracy of evaluators varied with experience when shown case data alone (accuracy, 57% to 82%) but improved with a teaching lecture (accuracy, 76% to 89%) and further improved with a novel algorithm (accuracy, 93% to 96%). Mixed stone compositions were the most incorrectly predicted type. Mobile application accuracy was 74%.\u0000\u0000\u0000CLINICAL RELEVANCE\u0000Use of the 4 preoperative parameters resulted in variable accuracy of urocystolith composition predictions among evaluators. The proposed novel algorithm improves accuracy for all clinicians, surpassing accuracy of the mobile application, and may help guide patient management.","PeriodicalId":514111,"journal":{"name":"Journal of the American Veterinary Medical Association","volume":"23 5","pages":"1-8"},"PeriodicalIF":0.0,"publicationDate":"2024-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140739935","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Laura R Van Vertloo, L. Sebbag, R. Allbaugh, K. Allenspach, David J Borts, J. Mochel
{"title":"Systemic absorption and gastrointestinal adverse effects from topical ketorolac and diclofenac ophthalmic solutions in healthy dogs.","authors":"Laura R Van Vertloo, L. Sebbag, R. Allbaugh, K. Allenspach, David J Borts, J. Mochel","doi":"10.2460/javma.23.12.0707","DOIUrl":"https://doi.org/10.2460/javma.23.12.0707","url":null,"abstract":"OBJECTIVE\u0000To investigate systemic absorption and gastrointestinal (GI) adverse effects of topical ketorolac 0.5% and diclofenac 0.1% ophthalmic solutions.\u0000\u0000\u0000ANIMALS\u000011 healthy purpose-bred Beagles.\u0000\u0000\u0000METHODS\u0000Dogs were randomly assigned to receive either ketorolac (n = 6) or diclofenac (5), 1 drop in both eyes 4 times daily for 28 days. Upper GI endoscopy was performed on days 0 and 29 with mucosal lesion scores (0 to 7) assigned to each region evaluated. Plasma samples were collected on days 14, 21, and 28 for measurement of diclofenac and ketorolac using high-performance liquid chromatography-mass spectrometry.\u0000\u0000\u0000RESULTS\u0000GI erosions and/or ulcers developed in all ketorolac-treated dogs and 1 of 5 diclofenac-treated dogs. Post-treatment mucosal lesion score for the antrum was higher in the ketorolac group than in the diclofenac group (P = .006) but not significantly different for any other region. Post-treatment antral mucosal lesion scores were significantly related to plasma ketorolac concentrations (P < .001). Ketorolac and diclofenac were detected in the plasma at all time points (median ketorolac day 14, 191 ng/mL; day 21, 173.5 ng/mL; and day 28, 179.5 ng/mL; and median diclofenac day 14, 21.1 ng/mL; day 21, 20.6 ng/mL; day 28, 27.5 ng/mL). Vomiting and decreased appetite events were observed uncommonly and were not significantly different between treatment groups.\u0000\u0000\u0000CLINICAL RELEVANCE\u0000GI ulceration and erosion developed after ophthalmic administration of ketorolac and diclofenac, with higher plasma concentrations and more severe GI lesions associated with ketorolac. Clients should be alerted to this potential risk with ophthalmic use and informed to watch for systemic clinical signs that would warrant veterinary reevaluation.","PeriodicalId":514111,"journal":{"name":"Journal of the American Veterinary Medical Association","volume":"43 2","pages":"1-10"},"PeriodicalIF":0.0,"publicationDate":"2024-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140736013","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
D. Marteles, Álex Gómez, S. Villanueva‐Saz, Carolina Naranjo, María C Aceña
{"title":"Intermammary mass in a 13-year-old intact female Spanish Alano dog.","authors":"D. Marteles, Álex Gómez, S. Villanueva‐Saz, Carolina Naranjo, María C Aceña","doi":"10.2460/javma.24.01.0052","DOIUrl":"https://doi.org/10.2460/javma.24.01.0052","url":null,"abstract":"","PeriodicalId":514111,"journal":{"name":"Journal of the American Veterinary Medical Association","volume":"37 2","pages":"1-3"},"PeriodicalIF":0.0,"publicationDate":"2024-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140738098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Scoping review of the use of mesenchymal stem and stromal cell products in cats, Part 2: current scope and efficacy.","authors":"Tracy L Webb, Craig B Webb","doi":"10.2460/javma.24.02.0080","DOIUrl":"https://doi.org/10.2460/javma.24.02.0080","url":null,"abstract":"A scoping review of published literature found 108 articles related to mesenchymal stem or stromal cell (MSC) use in cats. Twenty-four of the publications summarized the treatment of 192 cats with MSC products for 12 naturally occurring and induced diseases. These trials used a variety of cell sources, administration routes, delivery vehicles, and dosages. The majority of studies did not have a control group. The disease with the largest number of cats administered MSCs thus far is chronic kidney disease (n = 59 cats). The majority of cats had no adverse events associated with treatment, which supports continued interest in the potential use of MSC products to address unmet medical needs. Treatment outcomes of the 192 cats have ranged from no response to long-term cure, depending on the disease being treated and the particular study. Some of these early studies show promise and provide significant information to direct both the design and focus of larger clinical trials investigating the safety and efficacy of MSC treatment for veterinary and human applications.","PeriodicalId":514111,"journal":{"name":"Journal of the American Veterinary Medical Association","volume":"27 5","pages":"1-7"},"PeriodicalIF":0.0,"publicationDate":"2024-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140738912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Splenic hematoma and hemoperitoneum in a Thoroughbred racehorse after racing.","authors":"Erin Neville, John Pigott","doi":"10.2460/javma.24.01.0011","DOIUrl":"https://doi.org/10.2460/javma.24.01.0011","url":null,"abstract":"OBJECTIVE\u0000To describe the clinical presentation of a Thoroughbred filly with acute hemoperitoneum from a splenic source immediately after racing.\u0000\u0000\u0000ANIMAL\u0000A 3-year-old Thoroughbred filly used for racing and that had raced shortly before presentation to the hospital.\u0000\u0000\u0000CLINICAL PRESENTATION, PROGRESSION, AND PROCEDURES\u0000On presentation, the filly was quiet, alert, and responsive with a heart rate of 76 beats/min, pale mucous membranes, and absent borborygmi. All other physical examination parameters were within normal limits. Abdominal ultrasound was performed and revealed echogenic free abdominal fluid and a splenic hematoma. Abdominocentesis yielded sanguinous fluid with a PCV of 35%. The next day, repeat ultrasound revealed the splenic hematoma with capsular separation.\u0000\u0000\u0000TREATMENT AND OUTCOME\u0000The filly was treated overnight with isotonic crystalloid fluids and aminocaproic acid (40 mg/kg, IV, slow bolus over 30 minutes followed by 20 mg/kg, IV, q 6 h), potassium penicillin (22,000 IU/kg, IV, q 6 h), gentamicin (6.6 mg/kg, IV, q 24 h), and omeprazole (4 mg/kg, PO, q 24 h). The lowest PCV obtained from the filly was 36 hours after presentation. The filly stabilized with medical treatment and was discharged to a farm for further recuperation.\u0000\u0000\u0000CLINICAL RELEVANCE\u0000There are no published reports detailing hemoperitoneum of splenic origin in Thoroughbreds immediately after racing. Hemoperitoneum of splenic origin is not common in horses, with most cases of hemoperitoneum being secondary to acute trauma, neoplasia, parturition, or postoperative complications. While uncommon, this case raises awareness to another differential for a colicky horse immediately after racing.","PeriodicalId":514111,"journal":{"name":"Journal of the American Veterinary Medical Association","volume":"6 3","pages":"1-3"},"PeriodicalIF":0.0,"publicationDate":"2024-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140738312","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Heath W McAlexander, Janet A Grimes, Sharon L. Ullman, Grace Pei-Chun Lai, Megan Davis, Brett G Darrow, Vanna M. Dickerson
{"title":"Diagnostic and surgical treatment for traumatic bile peritonitis in dogs and cats.","authors":"Heath W McAlexander, Janet A Grimes, Sharon L. Ullman, Grace Pei-Chun Lai, Megan Davis, Brett G Darrow, Vanna M. Dickerson","doi":"10.2460/javma.24.01.0049","DOIUrl":"https://doi.org/10.2460/javma.24.01.0049","url":null,"abstract":"OBJECTIVE\u0000To describe short-term outcomes of dogs and cats undergoing surgery for traumatic bile peritonitis.\u0000\u0000\u0000ANIMALS\u000013 dogs and 4 cats.\u0000\u0000\u0000METHODS\u0000Multi-institutional, retrospective study. Medical records from 6 institutions were reviewed for cases of traumatic bile peritonitis between 2006 and 2022. Clinical presentation, additional injuries, surgical treatment, and outcome were recorded.\u0000\u0000\u0000RESULTS\u0000Trauma occurred a median of 2 (range, 1 to 22) and 4 (range, 1 to 22) days prior to presentation in dogs and cats, respectively. Total bilirubin was increased in 11 of 13 dogs and 2 of 4 cats. Rupture occurred at the common bile duct (CBD) in 10 dogs and 1 cat, gallbladder in 3 dogs, cystic duct in 2 cats, and hepatic duct in 1 dog and 1 cat. The most common surgeries were cholecystoduodenostomy and CBD repair in dogs and cholecystectomy in cats. Eleven of 13 dogs and all cats survived to hospital discharge (88.2% overall survival). Median follow-up in surviving dogs and cats was 35 days (range, 14 to 401) and 30 days (range, 14 to 90), respectively. One dog that underwent cholecystectomy experienced recurrent bile peritonitis 20 days postoperatively. Short-term survival following surgical treatment of traumatic bile peritonitis was excellent and recurrence appears uncommon. The most frequent site of rupture was the CBD in dogs and the cystic duct in cats.\u0000\u0000\u0000CLINICAL RELEVANCE\u0000Measurement of peritoneal bilirubin should be considered in dogs and cats with peritoneal effusion following trauma. Surgeons should be prepared to identify and address ruptures in locations other than the gallbladder.","PeriodicalId":514111,"journal":{"name":"Journal of the American Veterinary Medical Association","volume":"5 9","pages":"1-6"},"PeriodicalIF":0.0,"publicationDate":"2024-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140748426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
D. F. Barrantes Murillo, Rachel Pfeifle, Jenna W Stockler, David Alexander Martinez Rodriguez, Rachel L A L T Neto
{"title":"Hyperventilation in a premature neonatal calf.","authors":"D. F. Barrantes Murillo, Rachel Pfeifle, Jenna W Stockler, David Alexander Martinez Rodriguez, Rachel L A L T Neto","doi":"10.2460/javma.24.02.0118","DOIUrl":"https://doi.org/10.2460/javma.24.02.0118","url":null,"abstract":"","PeriodicalId":514111,"journal":{"name":"Journal of the American Veterinary Medical Association","volume":"12 S1","pages":"1-3"},"PeriodicalIF":0.0,"publicationDate":"2024-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140746192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Davide De Lorenzi, Giulia Maggi, D. Bertoncello, Francesco Porciello, M. C. Marchesi
{"title":"Dumon silicone stents can improve respiratory function in dogs with grade IV tracheal collapse: 12 cases (2019-2023).","authors":"Davide De Lorenzi, Giulia Maggi, D. Bertoncello, Francesco Porciello, M. C. Marchesi","doi":"10.2460/javma.23.12.0722","DOIUrl":"https://doi.org/10.2460/javma.23.12.0722","url":null,"abstract":"OBJECTIVE\u0000To evaluate the efficacy, complications, and outcome of Dumon silicone stent placement for dogs with grade IV tracheal collapse.\u0000\u0000\u0000ANIMALS\u000012 client-owned dogs.\u0000\u0000\u0000CLINICAL PRESENTATION\u0000Each dog was diagnosed with grade IV TC unresponsive to medical therapy and had severe obstructive respiratory failure.\u0000\u0000\u0000RESULTS\u000012 dogs were included in the study. By the end of the study, 5 of 12 (41.7%) remained alive, while 7 of 12 (58.3%) dogs died. Survival times after stent placement ranged from 97 to 1,310 days (mean, 822.43 days; median, 810 days). Three of the 12 (25%) dogs died spontaneously, while 4 of 12 (33.3%) were euthanized. The cause of death was determined for 6 of 7 (85.7%) dogs and was TC related for 3 of 7 (50%). Causes of death related to TC were progressive airway collapse (2/3 [66.6%]) and incoercible cough (1/3 [33.4%]). Complications occurred in 9 of 12 (75%) cases and included granulation tissue growth (3/12 [25%]), incoercible cough (2/12 [16.7%]), stent migration (1/12 [8.3%]), and stent deformation (1/12 [8.3%]). Reduction of obstructive dyspnea and episodes of asphyxiation was achieved after Dumon silicone stent placement.\u0000\u0000\u0000CLINICAL RELEVANCE\u0000The placement of an intraluminal Dumon silicone stent was a successful salvage treatment for TC in dogs that did not respond to medical management. Disease progression is inevitable, but substantial improvement of respiratory function may be achieved for months to years.","PeriodicalId":514111,"journal":{"name":"Journal of the American Veterinary Medical Association","volume":"196 2","pages":"1-7"},"PeriodicalIF":0.0,"publicationDate":"2024-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140746579","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Nutritional management of pancreatitis and concurrent disease in dogs and cats.","authors":"H. Cridge, Valerie J Parker, A. Kathrani","doi":"10.2460/javma.23.11.0641","DOIUrl":"https://doi.org/10.2460/javma.23.11.0641","url":null,"abstract":"Nutrition is considered a key part of the management of pancreatitis in dogs and cats. While limited prospective research exists, experimental studies, retrospective studies, and anecdote allow for formulation of nutritional guidelines. Historically, fat has been considered the key nutrient of interest in pancreatitis; however, other nutrients and dietary factors, including energy density, digestibility, protein, carbohydrates, and fiber, are all of importance in these patients. Indeed protein particle size may be of greater significance than dietary fat in the management of pancreatitis in cats. Low-fat gastrointestinal diets are frequently recommended in the initial management of pancreatitis in dogs, while hydrolyzed diets are often considered first-line diets in cats with pancreatitis. The presence or absence of comorbid disease may also alter nutritional recommendations. When diseases occur concurrently, the dietary strategies for the most life-threatening illness, or the illness with the greatest impact on quality of life, is recommended to be prioritized. Many dogs and cats with pancreatitis can be transitioned back to their prediagnosis diet or another commercial maintenance diet, provided that significant comorbid disease is absent. Use of a low-fat diet in the long term may be prioritized in dogs with recurrent episodes of pancreatitis.","PeriodicalId":514111,"journal":{"name":"Journal of the American Veterinary Medical Association","volume":"20 3","pages":"1-7"},"PeriodicalIF":0.0,"publicationDate":"2024-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140747897","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}