Chemical Papers最新文献_第9页

Magnetic modified montmorillonites as potential sorbent phases: characterization and sorption of triazine herbicides

IF 2.2 4区化学

Chemical Papers Pub Date : 2024-12-06 DOI: 10.1007/s11696-024-03839-y

Danieli S. Hakoyama, Michele C. W. Silvério, Luis Fernando A. Batista, Vander F. Melo, Marco T. Grassi, Gilberto Abate

{"title":"Magnetic modified montmorillonites as potential sorbent phases: characterization and sorption of triazine herbicides","authors":"Danieli S. Hakoyama, Michele C. W. Silvério, Luis Fernando A. Batista, Vander F. Melo, Marco T. Grassi, Gilberto Abate","doi":"10.1007/s11696-024-03839-y","DOIUrl":"10.1007/s11696-024-03839-y","url":null,"abstract":"<div><p>In the present work, montmorillonite (Mt) from two different sources was modified by a one-pot method based on the oxidative polymerization of aniline using Fe<sub>2</sub>(SO<sub>4</sub>)<sub>3</sub> and magnetite formation by coprecipitation. The magnetic materials were used for the concentration and extraction of six triazine pesticides from aqueous solutions by magnetic solid-phase extraction, and their quantification was done by liquid chromatography–diode array detection. The starting and modified materials were subjected to different characterizations, and the composite formation was confirmed by the modification of the chemical groups present in the mineral phases and their different morphologies. Under optimal sorption conditions, the sorption values obtained for magnetic Mt (MMt) and magnetic Mt-K10 (MMt-K10) were above 80% for all compounds, except hexazinone. The best results were observed for ametryn (96%) on MMt and simazine (95%) on MMt-K10. Based on the results, it can be noted that the low-cost magnetic modified materials demonstrated a very satisfactory sorption of the selected triazines, which present a wide range of polarity. This could allow the development of cheaper analytical methods, with sustainable sorbents, for the quantification of more polar contaminants in aqueous matrices.</p><h3>Graphical abstract</h3>\u0000<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":513,"journal":{"name":"Chemical Papers","volume":"79 1","pages":"593 - 598"},"PeriodicalIF":2.2,"publicationDate":"2024-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143108645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Unveiling Pretomanid profiling using LC–MS/MS: integrating in-silico toxicity assessment and molecular docking analysis

IF 2.2 4区化学

Chemical Papers Pub Date : 2024-12-05 DOI: 10.1007/s11696-024-03818-3

Anuj Nahata, Nachiket Joshi, Mital Patel

{"title":"Unveiling Pretomanid profiling using LC–MS/MS: integrating in-silico toxicity assessment and molecular docking analysis","authors":"Anuj Nahata, Nachiket Joshi, Mital Patel","doi":"10.1007/s11696-024-03818-3","DOIUrl":"10.1007/s11696-024-03818-3","url":null,"abstract":"<div><p>The presence of impurities in pharmaceutical formulations compromises their safety, posing significant concerns. Recent market recalls have highlighted this issue. Pretomanid (PMD), an antitubercular drug, has functional groups such as amine, imidazole, benzene ring substitution, and ether group, making it sensitive to hydrolysis. Stability and forced degradation investigations were conducted following the International Conference for Harmonization (ICH) protocol Q1A (R2). Under various stress conditions such as Hydrolytic (acidic, basic, neutral), Thermal, Photolytic, and Oxidative; total Sixteen new Degradation products (DPs) were identified. These DPs labeled DP 1 to DP 16, were successfully separated using Isocratic elution with a Kromasil C18 (250 × 4.6 mm; 5 μm) column. The LC–MS/MS compatible mobile phase comprise of Acetonitrile (ACN) and 10 mM Ammonium Acetate pH 4.5 (50:50; v/v), at a flow rate of 0.9 mL/min, with a 30-min runtime and a column temperature of 25 °C. The DPs were identified by LC-MSanalysis, and their structures were confirmed with LC–MS/MS fragmentation. Drug Degradation occurred due to majorly Oxidation, Hydrolysis, and Rearrangement mechanisms. Pretomanid was particularly sensitive to Alkali and Oxidative hydrolysis. Therefore, PMD must be protected from aqueous media, temperature, alkaline pH, moisture, and light during formulation and development. In silico toxicity and molecular docking, studies revealed DP 6 as a potential hit molecule with a higher docking score of -151.22 than PMD with comparative less toxicity.</p><h3>Graphical abstract</h3><div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":513,"journal":{"name":"Chemical Papers","volume":"79 2","pages":"817 - 837"},"PeriodicalIF":2.2,"publicationDate":"2024-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143583441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Quantitative determination of Na-luminolate by chemiluminescence method in pharmaceutical preparations

IF 2.2 4区化学

Chemical Papers Pub Date : 2024-12-05 DOI: 10.1007/s11696-024-03826-3

Olena Mozgova, Mykola Blazheyevskiy, Valeriy Moroz, Vladyslav Diadchenko

{"title":"Quantitative determination of Na-luminolate by chemiluminescence method in pharmaceutical preparations","authors":"Olena Mozgova, Mykola Blazheyevskiy, Valeriy Moroz, Vladyslav Diadchenko","doi":"10.1007/s11696-024-03826-3","DOIUrl":"10.1007/s11696-024-03826-3","url":null,"abstract":"<div><p>A procedure for the chemiluminescence determination of Na-luminolate (NaHL) was developed. It is based on the oxidation of luminol with diperoxysuccinic acid (DPSA) in an alkaline solution (pH 10.3). At concentrations of DPSA 5.8 × 10<sup>–4</sup> mol/L and NaHL in the range from 1.5 × 10<sup>–7</sup> to 1.02 × 10<sup>–6</sup> mol/L at pH 10.3 (in phosphate buffer solution), <i>I</i><sub>max</sub> is proportional to <i>c</i>(NaHL): <i>I</i><sub>max</sub> = (2.76 ± 0.30) × 10<sup>7</sup><i>c</i> + (0.34 ± 1.78) (r = 0.998). LOD = 6.10 × 10<sup>–8</sup> mol/L; LOQ = 2.03 × 10<sup>–7</sup> mol/L. The procedures were developed, and the possibility of quantitative determination of NaHL in sublingual tablets \"Galavit\" 25 mg and powder for preparing a solution for injection \"Galavit\" 100 mg using the method of chemiluminescence by reaction with DPSA was shown. RSD ≤ 2.2%, (δ = (x̅-μ) × 100%/μ = + 1.16%….. – 0.41%, respectively). The results of the determination of NaHL in tablets and powder for preparing a solution for injection of \"Galavit\" 100 mg by the proposed method agree with those obtained by the standard pharmacopeia method. The reliability of the obtained measurement results is proved by comparing the accepted reference value (μ) with the level of results of the proposed method: |(x̅-μ) × 100%/μ|< t<sub>α</sub>(0.95, n = 5) × RSD/√n.</p></div>","PeriodicalId":513,"journal":{"name":"Chemical Papers","volume":"79 2","pages":"915 - 922"},"PeriodicalIF":2.2,"publicationDate":"2024-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s11696-024-03826-3.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143583442","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Celebrating 50 years of the Bílik reaction: history and present

IF 2.2 4区化学

Chemical Papers Pub Date : 2024-12-04 DOI: 10.1007/s11696-024-03825-4

Zuzana Hricovíniová

{"title":"Celebrating 50 years of the Bílik reaction: history and present","authors":"Zuzana Hricovíniová","doi":"10.1007/s11696-024-03825-4","DOIUrl":"10.1007/s11696-024-03825-4","url":null,"abstract":"<div><p>Epimerization reactions catalyzed by transition metals have changed the previous methods used in the synthesis of rare carbohydrates. In July 2024, we commemorated the 95th anniversary of the birth of Prof. Vojtech Bílik, the discoverer of a new reaction in the synthesis of rare carbohydrates. Over fifty years ago, many sugars were generally prepared by the Lobry de Bruyn–Alberda van Ekenstein isomerization reaction, which was the simplest method for a long period. However, this approach was not very efficient and the epimeric aldose was usually obtained in lower yield than the ketose. A new methodology introduced by Bílik in the 1970′s showed that the synthesis of epimeric aldoses mediated by the molybdenum Mo(VI) catalyst could significantly improve the preparation of rare aldoses without undesirable side reactions. Due to the simplicity and high efficiency of the reaction, the stereospecific Mo(VI)-catalyzed transformation of aldoses was used for preparative purposes and soon gained international recognition. The Mo(VI)-catalyzed epimerization reaction of aldoses was named after its discoverer, and it is the only reaction in the chemical literature of carbohydrates named after a Slovak scientist. On this anniversary, we take the opportunity to summarize the scientific achievements in this field of research.</p></div>","PeriodicalId":513,"journal":{"name":"Chemical Papers","volume":"79 1","pages":"75 - 83"},"PeriodicalIF":2.2,"publicationDate":"2024-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s11696-024-03825-4.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143107827","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Mini-review on the evaluation of thermodynamic parameters for surfactants adsorption onto rock reservoirs: cEOR applications

IF 2.2 4区化学

Chemical Papers Pub Date : 2024-12-03 DOI: 10.1007/s11696-024-03832-5

Seif El Islam Lebouachera, Abir Boublia, Mohamed El Moundher Hadji, Mohammed Abdelfetah Ghriga, Djilali Tassalit, Mohamed Khodja, Bruno Grassl, Nadjib Drouiche

{"title":"Mini-review on the evaluation of thermodynamic parameters for surfactants adsorption onto rock reservoirs: cEOR applications","authors":"Seif El Islam Lebouachera, Abir Boublia, Mohamed El Moundher Hadji, Mohammed Abdelfetah Ghriga, Djilali Tassalit, Mohamed Khodja, Bruno Grassl, Nadjib Drouiche","doi":"10.1007/s11696-024-03832-5","DOIUrl":"10.1007/s11696-024-03832-5","url":null,"abstract":"<div><p>Understanding thermodynamic parameters such as Gibbs free energy (Δ<i>G</i>°), enthalpy (Δ<i>H</i>°), and entropy (Δ<i>S</i>°) is crucial for characterizing surfactant adsorption mechanisms in chemical enhanced oil recovery (cEOR). This paper synthesizes recent studies on the thermodynamics of surfactant adsorption onto various reservoirs rock types, with a focus on quantitative and qualitative parameters critical to optimizing cEOR processes. Generally, surfactant adsorption is exothermic; for example, adsorption of sodium dodecyl sulfate and cetyltrimethylammonium bromide on sandstone and carbonate rocks yields Δ<i>H</i>° values between − 8 and − 20 kJ mol<sup>−1</sup> under typical reservoirs conditions. However, adsorption behaviors are influenced by factors such as surfactant type, rock mineralogy, salinity, and temperature, with occasional endothermic interactions observed in high-temperature reservoirs or with specific non-ionic surfactants. A positive linear correlation between Δ<i>H</i>° and Δ<i>S</i>° is commonly observed, indicating that increases in exothermic enthalpy (more negative Δ<i>H</i>°) are associated with increases in entropy (positive Δ<i>S</i>°), suggesting that adsorption processes that promote greater interfacial disorder are energetically favorable. This review not only consolidates key thermodynamic concepts but also provides a comparative analysis of thermodynamic parameters across different rock-surfactant systems, identifying trends and gaps in the literature. By offering insights into the specific conditions that enhance surfactant performance, this study establishes a thermodynamic framework to guide surfactant selection and optimization in cEOR. These contributions aim to deepen understanding of adsorption behavior and inform more effective, tailored cEOR strategies.</p></div>","PeriodicalId":513,"journal":{"name":"Chemical Papers","volume":"79 2","pages":"655 - 666"},"PeriodicalIF":2.2,"publicationDate":"2024-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143583391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Synthesis and protective effect of 7-O-thiazole Oroxylin A derivative against diabetic nephropathy in streptozotocin-induced diabetes in Wistar rats

IF 2.2 4区化学

Chemical Papers Pub Date : 2024-12-03 DOI: 10.1007/s11696-024-03822-7

Yanlong Dang, Jiang Li

{"title":"Synthesis and protective effect of 7-O-thiazole Oroxylin A derivative against diabetic nephropathy in streptozotocin-induced diabetes in Wistar rats","authors":"Yanlong Dang, Jiang Li","doi":"10.1007/s11696-024-03822-7","DOIUrl":"10.1007/s11696-024-03822-7","url":null,"abstract":"<div><p>This study synthesized a 7-<i>O</i>-thiazole derivative of Oroxylin A (compound <b>1</b>) to assess its potential in treating diabetic nephropathy (DN) using high-fat diet (HFD) and streptozotocin (STZ) induced pancreatic <i>β</i>-cell toxicity in Wistar rats. The synthesis yielded a compound of high purity, which was tested for bioactivity in DN. The effects of compound <b>1</b> on body weight and fasting blood glucose levels were examined, revealing a positive impact on body weight and a dose-dependent reduction in glucose levels. Liver function markers (ALP, AST, and ALT) and renal function indicators (BUN, serum creatinine, and CCr) showed significant improvement, alongside enhancements in lipid profiles, including reductions in TC, TG, VLDL, and an increase in HDL. Compound <b>1</b> also reduced proteinuria, oxidative stress, and pro-inflammatory cytokine production in the kidneys. Pharmacokinetic analysis indicated that compound <b>1</b> is more bioavailable and less prone to metabolic inactivation than Oroxylin A, suggesting that thiazole derivatization prevents metabolic deactivation. These findings demonstrate the potential of the 7-<i>O</i>-thiazole derivative of Oroxylin A as a protective agent against diabetic nephropathy through multiple therapeutic actions.</p></div>","PeriodicalId":513,"journal":{"name":"Chemical Papers","volume":"79 2","pages":"859 - 869"},"PeriodicalIF":2.2,"publicationDate":"2024-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143583389","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Luteolin-loaded nanostructured lipid carriers using propolis wax and safflower oil: formulation, optimization, and characterization for antibacterial and antioxidant improvement

IF 2.2 4区化学

Chemical Papers Pub Date : 2024-12-02 DOI: 10.1007/s11696-024-03831-6

Negar Samadi, Mohammad Mohsenzadeh, Maryam Hashemi

{"title":"Luteolin-loaded nanostructured lipid carriers using propolis wax and safflower oil: formulation, optimization, and characterization for antibacterial and antioxidant improvement","authors":"Negar Samadi, Mohammad Mohsenzadeh, Maryam Hashemi","doi":"10.1007/s11696-024-03831-6","DOIUrl":"10.1007/s11696-024-03831-6","url":null,"abstract":"<div><p>Luteolin is one of the most common edible herbal flavonoids that has anti-inflammatory, antioxidant and anticancer effects. The aim of this study was to develop an optimized luteolin-loaded nanostructured lipid carrier (NLC) using propolis wax as the solid lipid and safflower oil as the liquid lipid via a melt emulsification-ultrasonication method. Response surface methodology was utilized to investigate the influence of total lipid concentration and luteolin content on particle size, polydispersity index (PDI), and encapsulation efficiency (EE) in order to determine the optimal NLC formulation. The optimized NLCs exhibited spherical particles with an average size of 120.904 nm, a PDI of 0.142, and an EE of 66.87%. The particles also demonstrated high physical stability over a 90-day period at 4, 25 and 37 °C. Differential scanning calorimetry, X-ray diffraction, and transform infrared spectroscopy analyses showed high compatibility and proper embedding of luteolin in NLC structure. The gastrointestinal release of luteolin from the NLC formulation followed a sustained pattern compared to free luteolin, indicating the absence of any unencapsulated form on its surface. Additionally, the antioxidant activity of luteolin-loaded NLCs (L-NLC), as measured by DPPH and Folin-Ciocalteu methods, was significantly higher than free luteolin after 30 days. The microbiological tests using the microdilution broth method showed that NLCs had more antimicrobial properties compared to free luteolin against examined foodborne pathogens. In conclusion, the developed NLCs hold great potential as a delivery system for luteolin encapsulation and can be applied in the food and drug industries.</p></div>","PeriodicalId":513,"journal":{"name":"Chemical Papers","volume":"79 2","pages":"995 - 1012"},"PeriodicalIF":2.2,"publicationDate":"2024-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143583386","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The ABTS-microzone plate and scanometry as a simple and fast colorimetric assay for determining the total antioxidant capacity of plant extract

IF 2.2 4区化学

Chemical Papers Pub Date : 2024-11-30 DOI: 10.1007/s11696-024-03813-8

Mochammad Amrun Hidayat, Hildawati Ilham, Indah Yulia Ningsih, Bambang Kuswandi

{"title":"The ABTS-microzone plate and scanometry as a simple and fast colorimetric assay for determining the total antioxidant capacity of plant extract","authors":"Mochammad Amrun Hidayat, Hildawati Ilham, Indah Yulia Ningsih, Bambang Kuswandi","doi":"10.1007/s11696-024-03813-8","DOIUrl":"10.1007/s11696-024-03813-8","url":null,"abstract":"<div><p>The 2,2′-azinobis-3-ethylbenzothiazoline-6-sulfonic acid (ABTS)-microzone plate as an antioxidant sensor was developed by immobilizing the ABTS reagent onto the screen-printed paper. The individual circular microzone, served as a sensing zone has a blue color that will decolorize within antioxidant addition in the concentration-dependent favor. The scanometric detection system that uses a flatbed scanner and color analysis program like ImageJ was applied to the antioxidant sensor, while its analytical performance was optimized by using quercetin. The use of the pre-generated ABTS radical for constructing the paper-based sensor, as well as the application of the scanometric method, is the novelty of this study. The result showed that the sensor showed a linear signal (<i>r</i> = 0.9997) within quercetin addition (0.1–1.0 mM) at 8 min with the detection limit (LOD) of quercetin at 0.03 mM and presented good precision (RSD < 3%) and accuracy (98–101% recovery) in total antioxidant capacity (TAC) determination. TAC of various plant extracts was successfully determined (as mM quercetin equivalent) by using the antioxidant sensor, while the result was parallel with that determined by the spectrophotometric method, suggesting the feasibility of the proposed method as an alternate method for TAC determination.</p></div>","PeriodicalId":513,"journal":{"name":"Chemical Papers","volume":"79 2","pages":"775 - 782"},"PeriodicalIF":2.2,"publicationDate":"2024-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143583383","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comprehensive optimization and kinetic-thermodynamic evaluation of methyl green adsorption from aqueous solutions using an innovative α-FeOOH@Luffa fiber composite

IF 2.2 4区化学

Chemical Papers Pub Date : 2024-11-29 DOI: 10.1007/s11696-024-03823-6

Rayane Diaf, Hacene Bendjeffal, Toufek Metidji, Yamina Berredjem

{"title":"Comprehensive optimization and kinetic-thermodynamic evaluation of methyl green adsorption from aqueous solutions using an innovative α-FeOOH@Luffa fiber composite","authors":"Rayane Diaf, Hacene Bendjeffal, Toufek Metidji, Yamina Berredjem","doi":"10.1007/s11696-024-03823-6","DOIUrl":"10.1007/s11696-024-03823-6","url":null,"abstract":"<div><p>This study introduces <i>α</i>-FeOOH@Luffa, a novel composite for the adsorptive removal of methyl green (MG) from aqueous solutions. Utilizing fractional factorial design (FrFD) and response surface methodology (RSM), we optimized six parameters to enhance the adsorption process. The findings reveal a maximum adsorption capacity of 256.32 mg g⁻<sup>1</sup> at an optimal pH of 9 within 60 min. The adsorption behavior aligns with the Langmuir isotherm and follows pseudo-second-order kinetics, indicating strong adsorption dynamics. The process is characterized as exothermic and spontaneous, supported by a high correlation between observed and predicted removal efficiencies (<i>R</i><sup>2</sup> = 98.03%). Furthermore, the composite exhibits excellent regeneration capabilities, maintaining adsorption efficiency across six consecutive cycles. These results underscore the potential of <i>α</i>-FeOOH@Luffa as a cost-effective and eco-friendly solution for wastewater treatment, paving the way for further investigations into its application for other persistent pollutants.</p><h3>Graphical abstract</h3>\u0000<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":513,"journal":{"name":"Chemical Papers","volume":"79 2","pages":"871 - 895"},"PeriodicalIF":2.2,"publicationDate":"2024-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143583381","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Antioxidant potential and chemical composition of essential oils from Mentha longifolia, Lavandula angustifolia, and Ocimum basilicum grown in the Oued Souf region, Algeria

IF 2.2 4区化学

Chemical Papers Pub Date : 2024-11-28 DOI: 10.1007/s11696-024-03814-7

Fatma Zohra Ayachi Amar, Mohamed Bilal Goudjil, Zineb Mahcene, Asma Ayachi Amor

{"title":"Antioxidant potential and chemical composition of essential oils from Mentha longifolia, Lavandula angustifolia, and Ocimum basilicum grown in the Oued Souf region, Algeria","authors":"Fatma Zohra Ayachi Amar, Mohamed Bilal Goudjil, Zineb Mahcene, Asma Ayachi Amor","doi":"10.1007/s11696-024-03814-7","DOIUrl":"10.1007/s11696-024-03814-7","url":null,"abstract":"<div><p>This study examined the antioxidant potential of essential oils (EOs) from <i>Mentha longifolia</i> (MEo), <i>Lavandula angustifolia</i> (LEo), and <i>Ocimum basilicum</i> (BEo) cultivated in Algeria’s arid Oued Souf region. GC-MS analysis highlighted unique chemical compositions, with LEo rich in linalool (21.37%) and linalyl acetate (30.92%), BEo high in phenylpropanoids (37.25%), especially estragole (20.65%) and linalool (30.17%), and MEo dominated by cis-isopulegone (59.68%). Antioxidant activity was evaluated via FRAP, DPPH, and TCA assays. BEo showed the highest FRAP activity (EC<span>(_{50})</span> = 2.96 ± 0.05 <span>(mu)</span>g/mL), followed by LEo and MEo (EC<span>(_{50})</span> = 5.08 ± 0.2 <span>(mu)</span>g/mL and 5.89 ± 0.1 <span>(mu)</span>g/mL, respectively). In the DPPH assay, BEo also exhibited the strongest radical-scavenging activity (IC<span>(_{50})</span> = 0.053 ± 0.45 mg/mL) compared to LEo (IC<span>(_{50})</span> = 25.55 ± 0.29 mg/mL) and MEo (IC<span>(_{50})</span> = 16.89 ± 0.023 mg/mL). Similarly, BEo displayed the greatest inhibition in the TCA assay (EC<span>(_{50})</span> = 3.5 ± 0.16 mg/mL). These findings underscore BEo’s remarkable antioxidant capacity, potentially linked to its rich phenylpropanoid profile, suggesting that environmental stressors in arid regions enhance the bioactive compound concentrations in essential oils. This structural resilience may make these oils powerful natural alternatives to synthetic antioxidants, offering promising applications for managing oxidative stress.</p><h3>Graphical abstract</h3><div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":513,"journal":{"name":"Chemical Papers","volume":"79 2","pages":"783 - 795"},"PeriodicalIF":2.2,"publicationDate":"2024-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143583619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0