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Nutritional composition, fatty acid content and antioxidant profile of Chinese chive (Allium odorum) instant spice mix 韭菜速溶香料的营养成分、脂肪酸含量及抗氧化特性
IF 2.5 4区 化学
Chemical Papers Pub Date : 2025-05-29 DOI: 10.1007/s11696-025-04108-2
Phuritshabam Vivekanandini Devi, Jaswinder Kaur Brar, Yaisna Rajkumari
{"title":"Nutritional composition, fatty acid content and antioxidant profile of Chinese chive (Allium odorum) instant spice mix","authors":"Phuritshabam Vivekanandini Devi,&nbsp;Jaswinder Kaur Brar,&nbsp;Yaisna Rajkumari","doi":"10.1007/s11696-025-04108-2","DOIUrl":"10.1007/s11696-025-04108-2","url":null,"abstract":"<div><p>The objective of the experiment was to formulate a nutritionally enhanced instant spice mix using Chinese chive (<i>Allium odorum)</i> and then assess its nutritional composition, fatty acid content, antioxidant profile, and conduct storage tests. Along with other frequently used spices, Chinese chives were put in varying amounts to the prepared dishes—dhal fry, vegetable soup, and sprouting bean salad—in order to assess their organoleptic qualities.Nutritional analysis shows a significant presence of dietary fiber (16.11 g/100 g), total phenol (988.76 GAE/100 g), total flavonoid (821.28 mg CE/100 g), and chlorophyll content (27.59–32.99 µ/g). In addition, it possess high antioxidant properties such as DPPH inhibition (47.07), ABTS inhibition (37.29), FRAP (2.57 µmolFe(II)/g), ORAC (4.17 µmol TE/g). Furthermore, an abundance of linoleic, α-linolenic and oleic acids was displayed. Chinese chive instant spice mix that displayed the highest level of acceptability was selected for storage studies for 90 days by determining moisture, free fatty acid, and peroxide values by withdrawing periodically every month. The spice mix's quality parameters did not significantly change; however, there was a minor increase in moisture content—from 7.54 to 7.74%. Nevertheless, no notable variations were discovered, indicating that the created spice blends may be kept for three months with little alterations. Because of its high nutritional and antioxidant potential, this study suggests that Chinese chives can be utilized to make a nutritious spice mix that delivers health-beneficial chemicals.</p></div>","PeriodicalId":513,"journal":{"name":"Chemical Papers","volume":"79 8","pages":"5087 - 5100"},"PeriodicalIF":2.5,"publicationDate":"2025-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145170400","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Iodide assisted synthesis of amides on carbon electrode: application to N,N-diethylaminoethyl amide derivatives 碘化物在碳电极上辅助合成酰胺:应用于N,N-二乙基氨基乙基酰胺衍生物
IF 2.5 4区 化学
Chemical Papers Pub Date : 2025-05-29 DOI: 10.1007/s11696-025-04120-6
Robby Gus Mahardika, Ade Danova, Elvira Hermawati, Anita Alni
{"title":"Iodide assisted synthesis of amides on carbon electrode: application to N,N-diethylaminoethyl amide derivatives","authors":"Robby Gus Mahardika,&nbsp;Ade Danova,&nbsp;Elvira Hermawati,&nbsp;Anita Alni","doi":"10.1007/s11696-025-04120-6","DOIUrl":"10.1007/s11696-025-04120-6","url":null,"abstract":"<div><p>Amide bonds are highly prevalent in natural products and pharmaceuticals, making them one of the most important functional groups, such as <i>N</i>,<i>N</i>-diethylaminoethyl amide group commonly found in drugs. This study presents a novel electrochemical method for the direct condensation of carboxylic acids and amines, utilizing triphenylphosphine as a coupling agent and iodide as a redox mediator. A key innovation of this method is the use of low-cost graphite electrodes, which provide a scalable alternative to platinum- or boron-doped diamond (BDD) electrodes. Additionally, tetrabutylammonium iodide (TBAI) was employed as a more efficient mediator than the other iodide sources, achieving yields of up to 84%. The process was performed under mild conditions, with high functional group tolerance, and allowed for the synthesis of various amides, including <i>N</i>,<i>N</i>-diethylaminoethyl amide derivatives. This work demonstrates the potential of carbon electrodes and iodide for sustainable and efficient electrochemical amide synthesis with advantages in cost, scalability, and pharmaceutical applications.</p></div>","PeriodicalId":513,"journal":{"name":"Chemical Papers","volume":"79 8","pages":"5219 - 5236"},"PeriodicalIF":2.5,"publicationDate":"2025-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145171410","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Chitosan-based adsorbents for adsorptive confiscation of antibiotic and NSAID contaminants from water bodies: a short review 壳聚糖吸附剂吸附吸附水体中抗生素和非甾体抗炎药污染物的研究进展
IF 2.5 4区 化学
Chemical Papers Pub Date : 2025-05-28 DOI: 10.1007/s11696-025-04112-6
Maithili Khapre, Anita Shekhawat, Prajakta Waghe, Shashikant Kahu, Ravin Jugade
{"title":"Chitosan-based adsorbents for adsorptive confiscation of antibiotic and NSAID contaminants from water bodies: a short review","authors":"Maithili Khapre,&nbsp;Anita Shekhawat,&nbsp;Prajakta Waghe,&nbsp;Shashikant Kahu,&nbsp;Ravin Jugade","doi":"10.1007/s11696-025-04112-6","DOIUrl":"10.1007/s11696-025-04112-6","url":null,"abstract":"<div><p>The development in science and technology over the past few decades has changed the world a lot. In view of the changes caused in the environment, the results are disturbing. One such example is the bloom of the pharmaceutical industry which has lead to synthesis of many drugs which possess potency for curing a number of diseases. However, the accumulation of the unused drugs in semi-metabolized state in the natural water systems through manufacturing plants, hospitals or consumers at large, have led to a serious trouble. This review article aims to present a short summary of the various methods proposed for the removal of antibiotics and non-steroidal Anti-Inflammatory Drugs (NSAIDs) from aquatic systems through adsorbents synthesized using chitosan and its different structurally modified versions. Chitosan, being abundantly available in nature, has become the most preferable material as adsorbent for a variety of contaminants including dyes, heavy metals, fluoride, drugs, fertilizers, etc. Thus, we present three important structural modifications of chitosan namely crosslinked/grafted chitosan, chitosan hydrogels/microspheres and chitosan composites as potential adsorbents for commonly used antibiotics and drugs. The study also includes the optimized pH conditions for adsorption, isotherm, kinetics and mechanism of adsorption as well as maximum adsorption capacity obtained for the drug.</p><h3>Graphic abstract</h3>\u0000<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":513,"journal":{"name":"Chemical Papers","volume":"79 7","pages":"4087 - 4107"},"PeriodicalIF":2.5,"publicationDate":"2025-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145145527","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Integrating experimental and computational approaches to evaluate quinoline derivative as corrosion inhibitor for Q235 steel in simulated acidizing fluid under static and hydrodynamic conditions 结合实验和计算方法评价喹啉衍生物对Q235钢在静、动模拟酸化液中的缓蚀剂作用
IF 2.5 4区 化学
Chemical Papers Pub Date : 2025-05-28 DOI: 10.1007/s11696-025-04116-2
Abdullah K. Alanazi
{"title":"Integrating experimental and computational approaches to evaluate quinoline derivative as corrosion inhibitor for Q235 steel in simulated acidizing fluid under static and hydrodynamic conditions","authors":"Abdullah K. Alanazi","doi":"10.1007/s11696-025-04116-2","DOIUrl":"10.1007/s11696-025-04116-2","url":null,"abstract":"<div><p>This research examines the synthesis and anti-corrosion properties of quinolin derivative (QD), in 15% HCl solution, for the protection of Q235 steel. The weight loss, electrochemical, and surfaces examination methods reveal the structural look of the steel surface. The findings show that at 30 °C, QD performs at a maximum of 93.39% (125 mg/L). Up to 60 °C, the effectiveness of inhibition rises with temperature; after that, it decreases. Under comparison to static conditions, QD performs superior within hydrodynamic conditions. Morphology studies of surface characterization confirm the formation of inhibitory film of QD above the metal. Additionally, molecular and atomic level understanding the way of interaction between the QD and Q235 steel substrate was provided by the density functional theory (DFT) and molecular dynamic simulation (MD) outcomes.</p></div>","PeriodicalId":513,"journal":{"name":"Chemical Papers","volume":"79 8","pages":"5167 - 5183"},"PeriodicalIF":2.5,"publicationDate":"2025-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145170107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Production of bio-dicalcium phosphate from by-product of processing of catfish (Pangasianodon hypophthalmus) filet 鲶鱼鱼片加工副产物生产生物磷酸二钙的研究
IF 2.5 4区 化学
Chemical Papers Pub Date : 2025-05-28 DOI: 10.1007/s11696-025-04104-6
Kien-Quoc Le, Lien-Huong Huynh, Bich-Thuyen Nguyen Thi, Viet Nhan-Hoa Nguyen, Nam Nghiep Tran, Quoc-Phong Ho
{"title":"Production of bio-dicalcium phosphate from by-product of processing of catfish (Pangasianodon hypophthalmus) filet","authors":"Kien-Quoc Le,&nbsp;Lien-Huong Huynh,&nbsp;Bich-Thuyen Nguyen Thi,&nbsp;Viet Nhan-Hoa Nguyen,&nbsp;Nam Nghiep Tran,&nbsp;Quoc-Phong Ho","doi":"10.1007/s11696-025-04104-6","DOIUrl":"10.1007/s11696-025-04104-6","url":null,"abstract":"<div><p>Bio-dicalcium phosphate (BDCP) is a natural source of calcium that can be extracted from biological sources such as catfish bones, a by-product of catfish. The huge amount of fish bone generated from the processing of catfish in Vietnam is a potential source for bio-calcium. The production of BDCP from this by-product can increase its value. Catfish bones collected from the factory were stewed and treated with NaOH solution to remove organic impurities. The pre-treated catfish bones were then calcined and ground to fine powder before converting to dicalcium phosphate. Important factors affecting the conversion including H<sub>3</sub>PO<sub>4</sub> concentration, FBP concentration in H<sub>3</sub>PO<sub>4</sub> solution, precipitation pH, reaction time, and reaction temperature were investigated. XRD, SEM, FTIR, and TGA were employed to characterize the BDCP products. BDCP with high purity was obtained at H<sub>3</sub>PO<sub>4</sub> 3 M, FBP concentration in H<sub>3</sub>PO<sub>4</sub> of 80 g L<sup>−1</sup>, pH 5, reaction time 60 min at 60 °C. The product exhibited a notably high crystallinity (&gt; 96%) with particle sizes, ranging from 1 to 3 μm, and crystal sizes of approximately 8 nm. Elemental profiles analysis revealed that the product contains not only a high percentage of calcium and phosphorus but also other essential minerals. The process can be claimed as a viable method for acquiring premium-grade bio-calcium.</p><h3>Graphical abstract</h3>\u0000<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":513,"journal":{"name":"Chemical Papers","volume":"79 8","pages":"5039 - 5050"},"PeriodicalIF":2.5,"publicationDate":"2025-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145170105","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Biodegradation of chloramphenicol by Aspergillus neoflavipes AJC3 新黄曲霉AJC3对氯霉素的生物降解
IF 2.5 4区 化学
Chemical Papers Pub Date : 2025-05-28 DOI: 10.1007/s11696-025-04123-3
Raveena Ann Alex, Jayanthi Abraham
{"title":"Biodegradation of chloramphenicol by Aspergillus neoflavipes AJC3","authors":"Raveena Ann Alex,&nbsp;Jayanthi Abraham","doi":"10.1007/s11696-025-04123-3","DOIUrl":"10.1007/s11696-025-04123-3","url":null,"abstract":"<div><p>The possibility of environmental contamination associated with chloramphenicol requires special attention. The primary challenges in the biodegradation of chloramphenicol from the contaminated environment are obtaining effective antibiotic-degrading microbes of pure cultures and determining the entire metabolic pathway involved in efficient degradation. The potent strain <i>Aspergillus neoflavipes</i> AJC3 was able to degrade 98.70% of chloramphenicol at a concentration of 50 mg/L within 8 d. The biodegradation pattern of chloramphenicol was evaluated by employing high-performance liquid chromatography (HPLC) and validated through gas chromatography mass spectroscopy (GC–MS), liquid chromatography mass spectrometry (LC–MS) and Fourier transform infrared spectroscopy (FTIR). Three metabolic compounds were identified during the chloramphenicol biodegradation process and the degradation pathway involved zero-order and first-order kinetics model according to the kinetics energy. And to evaluate the effects of chloramphenicol in aquatic environment, toxicity studies were conducted using the nauplii and cysts of <i>Artemia salina</i> and the nauplii mortality was evaluated at 24 h.</p><h3>Graphical abstract</h3>\u0000<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":513,"journal":{"name":"Chemical Papers","volume":"79 8","pages":"5249 - 5259"},"PeriodicalIF":2.5,"publicationDate":"2025-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145170106","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Heterocyclic compounds and hybrid materials: green corrosion inhibitors for ferrous and non-ferrous materials 杂环化合物和杂化材料:黑色和有色材料的绿色缓蚀剂
IF 2.5 4区 化学
Chemical Papers Pub Date : 2025-05-27 DOI: 10.1007/s11696-025-04122-4
Walid Daoudi, Amarpreet Kour Bhatia, Shippi Dewangan, Rubina Sahin, Sonali Loya, Dakeshwar Kumar Verma, Ibrahim A. Naguib, Abdelmalik El Aatiaoui
{"title":"Heterocyclic compounds and hybrid materials: green corrosion inhibitors for ferrous and non-ferrous materials","authors":"Walid Daoudi,&nbsp;Amarpreet Kour Bhatia,&nbsp;Shippi Dewangan,&nbsp;Rubina Sahin,&nbsp;Sonali Loya,&nbsp;Dakeshwar Kumar Verma,&nbsp;Ibrahim A. Naguib,&nbsp;Abdelmalik El Aatiaoui","doi":"10.1007/s11696-025-04122-4","DOIUrl":"10.1007/s11696-025-04122-4","url":null,"abstract":"<div><p>With growing environmental awareness and changing regulations that restrict conventional corrosion inhibitors due to their toxicity, corrosion inhibitors are becoming interesting. Many organic compounds containing heteroatoms such as phosphorus, sulphur, oxygen and nitrogen are remarkably effective at inhibiting corrosion. The heteroatoms with the best corrosion-inhibiting properties follow the order P &gt; S &gt; N &gt; O. Their effectiveness is attributed to the inclusion in the molecule of a lone pair and pi electrons, which facilitate their deposition on the metal surface. Extensive research has shown that virtually all corrosion inhibitors contain one or more heteroatoms, often in the form of polar functional groups, which enhances their propensity to adsorb to metal surfaces. Since then, much research on the use of N, P and S atoms has been published, but studies on the use of oxygen, oxygen–nitrogen and oxygen–nitrogen-sulphur heteroatoms are rare. Therefore, the aim of this study was to describe a variety of corrosion inhibitors containing oxygen, oxygen–nitrogen and oxygen–nitrogen-sulphur heteroatoms.</p></div>","PeriodicalId":513,"journal":{"name":"Chemical Papers","volume":"79 8","pages":"4865 - 4882"},"PeriodicalIF":2.5,"publicationDate":"2025-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145171090","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Synthesis of thiophene-based imine and phosphoazometine compounds: in vitro antiproliferative, antimicrobial, antioxidant, carbonic anhydrase I and II enzyme inhibition evaluations and molecular docking study 噻吩基亚胺和磷偶氮胺化合物的合成:体外抗增殖、抗菌、抗氧化、碳酸酐酶I和II酶抑制评价及分子对接研究
IF 2.5 4区 化学
Chemical Papers Pub Date : 2025-05-27 DOI: 10.1007/s11696-025-04096-3
Kubra Ozturk, Muhammet Saban Tanyildizi, Harun Ciftci, Ozlem Gundogdu Aytac
{"title":"Synthesis of thiophene-based imine and phosphoazometine compounds: in vitro antiproliferative, antimicrobial, antioxidant, carbonic anhydrase I and II enzyme inhibition evaluations and molecular docking study","authors":"Kubra Ozturk,&nbsp;Muhammet Saban Tanyildizi,&nbsp;Harun Ciftci,&nbsp;Ozlem Gundogdu Aytac","doi":"10.1007/s11696-025-04096-3","DOIUrl":"10.1007/s11696-025-04096-3","url":null,"abstract":"<div><p>New thiophene-based imine ((E)-N,N-dimethyl-4-((thiophen-2-yl-methylene)amino)aniline) (<b>Y6</b>), amine (N1,N1-dimethyl-N4-(thiophen-2)-ylmethyl)benzene-1,4-diamine) (<b>Y6a</b>), and phosphoacomethine (diphenyl (((4-(dimethylamino)phenyl)amino)(thiophen-2-yl)methyl)phosphate) (<b>Y6b</b>) compounds were synthesized, and their structures were thoroughly analyzed. The synthesized compounds were determined to have antioxidant effects and strong inhibitory effects against human carbonic anhydrases I and II (hCA I and hCA II) isoforms. All compounds exhibited significant antioxidant properties, with compound <b>Y6a</b> showing an IC<sub>50</sub> value of 5.13 µg/mL, which was significantly lower than the IC<sub>50</sub> of ascorbic acid (17.55 µg/mL). The compounds also demonstrated potent inhibitory effects against hCA I and hCA II isoenzymes, with IC<sub>50</sub> values of 1.96 µM (<b>Y6</b>), 8.25 µM (<b>Y6a</b>), and 0.46 µM (<b>Y6b</b>) for hCA I, and 1.89 µM (<b>Y6</b>), 0.56 µM (<b>Y6a</b>), and 1.02 µM (<b>Y6b</b>) for hCA II. In addition to the experimental findings, molecular docking studies of the synthesized compounds were performed. Antimicrobial tests of the synthesized compounds were performed, and it was determined that they have antibacterial activity against bacterial strains. Additionally, all three compounds exhibited promising antiproliferative activity in the MCF-7 breast cancer cell line, with IC<sub>50</sub> values of 56.58 µM (<b>Y6</b>), 51.30 µM (<b>Y6a</b>), and 40.01 µM (<b>Y6b</b>). Notably, the IC<sub>50</sub> value of Y6b (40.01 µM) was found to be comparable to that of cisplatin, one of the effective chemotherapy drugs, and has the potential to be a drug or drug precursor.</p><h3>Graphical abstract</h3>\u0000<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":513,"journal":{"name":"Chemical Papers","volume":"79 7","pages":"4735 - 4751"},"PeriodicalIF":2.5,"publicationDate":"2025-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145145469","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A review on nanomaterials: introduction, synthesis, characterization, and applications 纳米材料的介绍、合成、表征及其应用
IF 2.5 4区 化学
Chemical Papers Pub Date : 2025-05-26 DOI: 10.1007/s11696-025-04107-3
Reshma, Hussain Shaik, Kasi Venkatesan, Abbu Venugopal, Md Kadeer, Veera Somaiah Puppala
{"title":"A review on nanomaterials: introduction, synthesis, characterization, and applications","authors":"Reshma,&nbsp;Hussain Shaik,&nbsp;Kasi Venkatesan,&nbsp;Abbu Venugopal,&nbsp;Md Kadeer,&nbsp;Veera Somaiah Puppala","doi":"10.1007/s11696-025-04107-3","DOIUrl":"10.1007/s11696-025-04107-3","url":null,"abstract":"<div><p>The importance of nanotechnology and nanoscience evolution has been highlighted by recent technological advancements. A multidisciplinary field of study, nanotechnology encompasses materials science, physics, chemistry, and other engineering sciences. Nanotechnology is being used more and more in almost every branch of science and technology. The current review discusses a brief history of nanomaterials and the different types of nanoparticles and the methods used in their manufacture and characterization. Although a lot of methods and uses have been documented in the previous five years, we carefully concentrated on the general synthesis methods, characterization techniques, and uses of nanomaterials here in order to give aspiring researchers a general understanding.</p></div>","PeriodicalId":513,"journal":{"name":"Chemical Papers","volume":"79 7","pages":"4075 - 4085"},"PeriodicalIF":2.5,"publicationDate":"2025-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145145000","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Green synthesis of Cu nanoparticles using Biarum chaduchrum leaf extract and their efficacy against multi-drug-resistant Mycobacterium tuberculosis 用苦荞麦叶提取物绿色合成纳米铜及其对多重耐药结核分枝杆菌的疗效研究
IF 2.5 4区 化学
Chemical Papers Pub Date : 2025-05-26 DOI: 10.1007/s11696-025-04102-8
Xiaoguo Zhang, Zaiqin Ling
{"title":"Green synthesis of Cu nanoparticles using Biarum chaduchrum leaf extract and their efficacy against multi-drug-resistant Mycobacterium tuberculosis","authors":"Xiaoguo Zhang,&nbsp;Zaiqin Ling","doi":"10.1007/s11696-025-04102-8","DOIUrl":"10.1007/s11696-025-04102-8","url":null,"abstract":"<div><p>Tuberculosis is a leading chronic bacterial infection caused by <i>Mycobacterium tuberculosis</i> (<i>M. tuberculosis</i>). The current therapeutic management of <i>M. tuberculosis</i> is insufficient due to the prolonged course of treatment and undesired adverse effects that may lead to therapy failure and the development of drug-resistant tuberculosis, which in turn represents crucial challenges to the management of tuberculosis worldwide. <i>Biarum chaduchrum leaf</i> extract was used for green synthesis of copper (Cu)- nanoparticles (NPs), and the characteristics of Cu-NPs were determined by DLS, SEM, UV–Vis, zeta potential, and XRD. This study aimed to investigate the antibacterial activity and cytotoxicity of biosynthesized Cu-NPs in comparison with current antibiotic options against MDR M. tuberculosis and human A549 lung cells. The synthesized Cu-NPs exhibited a spherical structure with an average diameter of ~ 214 nm and a zeta potential of − 30 mV. The findings of MIC and MBC investigations revealed that Cu-NPs significantly reduced the viability of MDR tuberculosis and inhibited the growth of bacteria comparable to rifampin, isoniazid, linezolid, moxifloxacin, and levofloxacin (<i>p</i>-value &lt; 0.05). However, the CC50 value of NPs was lower than selected antibiotics (<i>p</i>-value &lt; 0.05). These findings may suggest the promising therapeutic efficacy of green synthesized Cu-NPs against MDR tuberculosis. Nevertheless, further investigations, particularly in vivo studies, are crucially required to evaluate the long-term safety and therapeutic potential of Cu-NPs.</p></div>","PeriodicalId":513,"journal":{"name":"Chemical Papers","volume":"79 8","pages":"5009 - 5022"},"PeriodicalIF":2.5,"publicationDate":"2025-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145169873","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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