Chemical PapersPub Date : 2025-06-23DOI: 10.1007/s11696-025-04179-1
Vidya Saraswathi A, Karunakara Naregundi, Vikash Mishra, A. Princy, S. Masilla Moses Kennedy, M. I. Sayyed, T. A. Hanafy, Sudha D. Kamath
{"title":"Temperature-dependent luminescence and defect centre analysis of thermally stable cerium-doped aluminosilicate phosphors","authors":"Vidya Saraswathi A, Karunakara Naregundi, Vikash Mishra, A. Princy, S. Masilla Moses Kennedy, M. I. Sayyed, T. A. Hanafy, Sudha D. Kamath","doi":"10.1007/s11696-025-04179-1","DOIUrl":"10.1007/s11696-025-04179-1","url":null,"abstract":"<div><p>This study aims to conduct a comprehensive characterisation of Sr<sub>2</sub>Al<sub>2</sub>SiO<sub>7</sub>: Ce phosphors, addressing critical gaps in existing research, particularly the limited exploration of the correlation between thermoluminescence and electron spin resonance phenomena, as well as the absence of reports on the temperature-dependent luminescence characteristics of thermally stable cerium-doped aluminosilicate phosphors. Advanced spectroscopic and analytical techniques were employed to elucidate the complex electronic states and defect centres within the crystal lattice of these phosphors. Density functional theory simulations were utilised to explain the energy gap discovered through diffuse reflectance spectroscopy studies, with the density of states analysis attributing the presence of electronic density states near the valence band to the addition of Ce<sup>3+</sup> dopant. Temperature-dependent luminescence studies revealed exceptional thermal stability, with only a 15% loss in luminescence intensity at 210 °C, highlighting the material’s potential for high-performance LED applications. This research emphasises the novel correlation between thermoluminescence and electron spin resonance, providing valuable insights into defect-assisted recombination processes and the thermoluminescence emission mechanism. The study’s findings bridge theoretical and experimental frameworks, establishing Sr<sub>2</sub>Al<sub>2</sub>SiO<sub>7</sub>: Ce as an innovative material with promising applications in γ-dosimetry, optoelectronic devices, and next-generation LED technologies. This work underscores the significance of exploring previously unexamined aspects of cerium-doped aluminosilicate phosphors, contributing to advancements in luminescent materials.</p></div>","PeriodicalId":513,"journal":{"name":"Chemical Papers","volume":"79 9","pages":"6129 - 6145"},"PeriodicalIF":2.5,"publicationDate":"2025-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144918545","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Chemical PapersPub Date : 2025-06-23DOI: 10.1007/s11696-025-04157-7
Humeyra Mert, Ömer Kayır, İbrahim Bilici, Büşra Moran, Hacer Doğan
{"title":"Green synthesis of reduced graphene oxide using parsley leaf extract: exploring antioxidant, anticancer, and wound healing potential","authors":"Humeyra Mert, Ömer Kayır, İbrahim Bilici, Büşra Moran, Hacer Doğan","doi":"10.1007/s11696-025-04157-7","DOIUrl":"10.1007/s11696-025-04157-7","url":null,"abstract":"<div><p>The present study investigates the use of parsley leaf extract as a green-reducing agent for the production of reduced graphene oxide (rGO) from graphene oxide (GO), which was prepared using the improved Hummers method. The successful reduction of GO was verified through various characterization methods, including FTIR, XRD, DSC, UV, and zeta potential analyses, which revealed notable changes in the structural and thermal characteristics of the resulting material. The reduction process and the removal of oxygen-containing groups were confirmed utilizing FTIR and XRD analyses, while DSC analysis highlighted the thermal differences between GO and rGO. LC–MS/MS analyses identified the key phenolic compounds present in the parsley leaf extract responsible for the reduction process. Biological evaluations demonstrated that both GO and rGO were biocompatible, with rGO exhibiting notable anticancer activity against colon and breast cancer cells, including a 70% reduction in cell viability and significant apoptotic effects. Genotoxicity tests demonstrated that while GO exhibited mild genotoxic effects, rGO was non-genotoxic, indicating its suitability for biological applications. The effectiveness of rGO in both eliminating oxidative damage and accelerating the wound healing process was also clearly demonstrated in the oxidative damage test and scratch assay. These findings illustrate that parsley leaf extract is an efficient, environmentally benign reducing agent for producing rGO with promising potential for cancer therapy and other biomedical applications.</p><h3>Graphical abstract</h3>\u0000<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":513,"journal":{"name":"Chemical Papers","volume":"79 9","pages":"5843 - 5859"},"PeriodicalIF":2.5,"publicationDate":"2025-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144918546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"MOF-tungsten composite (MIL-88B(Fe)@WO3) for photocatalytic degradation of rhodamine-B under UV light","authors":"Ekin Santoso Sim, Rinda Wardhani, Felycia Edi Soetaredjo, Jindrayani Nyoo Putro, Shella Permatasari Santoso, Jenni Lie, Hardy Shuwanto, Nyoman Puspa Asri, Alfin Kurniawan, Suryadi Ismadji","doi":"10.1007/s11696-025-04166-6","DOIUrl":"10.1007/s11696-025-04166-6","url":null,"abstract":"<div><p>A MIL-88B(Fe)@WO<sub>3</sub> composite material was used in this work as a photocatalyst for degrading the synthetic dye rhodamine-B in water. The synthesis of MIL-88B(Fe)@WO<sub>3</sub> was achieved by the solvothermal technique at 150 °C for 12 h. The introduction of WO<sub>3</sub> into the MIL-88B(Fe) framework has a positive effect on the pore structure of the composite material produced. The BET surface area and total pore volume exhibit a direct proportionality to the magnitude of the applied WO<sub>3</sub> ratio. A reduction in the concentration of rhodamine-B was observed when the degradation of rhodamine-B was carried out in the presence of UV light and catalyst. However, this reduction was not as significant as the degradation of rhodamine-B in the presence of UV light, catalyst, and H<sub>2</sub>O<sub>2</sub>. The present study also provides the process underlying the photodegradation of rhodamine-B dyes. Except for the M<sub>1</sub>W<sub>2</sub> catalyst, nearly all systems have a greater R<sup>2</sup> value for the first-order kinetic equation. The reusability analysis revealed a modest decrease in the performance of the M<sub>1</sub>W<sub>1</sub> composite as the number of cycles increased. However, its efficacy remained largely unaffected even after undergoing a degradation reaction and subjected to several washings.</p></div>","PeriodicalId":513,"journal":{"name":"Chemical Papers","volume":"79 9","pages":"5971 - 5986"},"PeriodicalIF":2.5,"publicationDate":"2025-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144918544","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Chemical PapersPub Date : 2025-06-23DOI: 10.1007/s11696-025-04167-5
Kh. S. Shaaban, Ateyyah M. Al-Baradi, Dalal Abdullah Aloraini
{"title":"A promising alternative: a pathway to superior mechanical and radiation shielding performance of Na2O-B2O3-SiO2-Al2O3-TiO2 glass system","authors":"Kh. S. Shaaban, Ateyyah M. Al-Baradi, Dalal Abdullah Aloraini","doi":"10.1007/s11696-025-04167-5","DOIUrl":"10.1007/s11696-025-04167-5","url":null,"abstract":"<div><p>In this study, a series of new glass samples with the composition (<span>(15-x)</span>) Na<sub>2</sub>O-67B<sub>2</sub>O<sub>3</sub>-13SiO<sub>2</sub>-5Al<sub>2</sub>O<sub>3</sub>-<span>(x)</span> TiO<sub>2</sub>, where x = 0:10 mol% were manufactured. The density (<span>(rho)</span>) increased with the increase in TiO<sub>2</sub> concentration due to its higher molecular weight. This increase in (<span>(rho)</span>) correspondingly enhanced the longitudinal <span>({V}_{L})</span>, transverse <span>({V}_{T})</span> velocities and elastic moduli, including longitudinal (<i>L</i>), transverse (<i>G</i>), bulk (<i>K</i>), and Young’s (<i>Y</i>) moduli. <span>({V}_{L})</span> increased from 4980 to 5455 while <span>({V}_{T})</span> rose from 2685 to 2915 m/s. Similarly, the values of L, <i>G</i>, <i>K</i>, and <i>Y</i> (GPa) exhibited consistent upward trends, ranging from 71.82 to 128.8, 20.88 to 36.75, 44 to 79.7, and 54.16 to 95.6, respectively. The results showed that increasing TiO<sub>2</sub> content inside the composite enhances the shielding ability against ionizing radiation. The shielding ability of BSTi-10 > BSTi-7.5 > BSTi-5 > BSTi-2.5 > BSTi-0 at all discussed energy photons. Future work will focus on optimizing the glass composition for enhanced mechanical and shielding properties while evaluating the glasses’ long-term durability and performance under various environmental and irradiation conditions.</p></div>","PeriodicalId":513,"journal":{"name":"Chemical Papers","volume":"79 9","pages":"5987 - 5996"},"PeriodicalIF":2.5,"publicationDate":"2025-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144918543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Chemical PapersPub Date : 2025-06-22DOI: 10.1007/s11696-025-04176-4
Peng Gu
{"title":"Optimizing dielectric attributes of NiO/P(VDF–HFP) composite films through filling fine α-Al2O3 particles","authors":"Peng Gu","doi":"10.1007/s11696-025-04176-4","DOIUrl":"10.1007/s11696-025-04176-4","url":null,"abstract":"<div><p>Dielectric composites with high dielectric constant, minimal dielectric loss and low conductivity can well serve for energy storage capacitors. High dielectric loss is not favorable due to large energy waste. Here, to improve dielectric constant of poly(vinylidene fluoride–hexafluoropropylene) by electric percolation, semiconducting NiO filler was added to form composites. However, high leakage current from interfaces can lead to high dielectric loss. Doping insulating α-Al<sub>2</sub>O<sub>3</sub> particles with stable structure, low chemical activity and high modulus into above binary composites can reduce dielectric loss. By changing NiO dose, dielectric constant was well tailored. Dose of α-Al<sub>2</sub>O<sub>3</sub> was left unchanged. Dielectric loss, conductivity and dielectric constant of composites were measured. By the same NiO loading, dielectric loss, conductivity and dielectric constant in ternary composites can be reduced, compared with binary composites. The optimal ternary composite should contain 35 wt% NiO and 4 wt% α-Al<sub>2</sub>O<sub>3</sub>. Optimized dielectric traits of this composite can be reflected by dielectric constant of ~ 64 and dielectric loss of ~ 0.27 under 100 Hz electric field.</p></div>","PeriodicalId":513,"journal":{"name":"Chemical Papers","volume":"79 9","pages":"6091 - 6101"},"PeriodicalIF":2.5,"publicationDate":"2025-06-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144918560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Chemical PapersPub Date : 2025-06-22DOI: 10.1007/s11696-025-04178-2
Hadiza Adamu Dawi, Taofik Olatunde Uthman, Serdar Surgun, Abdullahi Muhammad Sokoto
{"title":"Nickel-infused zeolite catalytic upgrade of pyrolysis oil from lignocellulose fibers of Syzygium cumini leaf litter for biofuel production","authors":"Hadiza Adamu Dawi, Taofik Olatunde Uthman, Serdar Surgun, Abdullahi Muhammad Sokoto","doi":"10.1007/s11696-025-04178-2","DOIUrl":"10.1007/s11696-025-04178-2","url":null,"abstract":"<div><p>Although pyrolysis oils have been identified as a cleaner renewable and sustainable fuel source, their application is limited due to undesirable properties including high viscosity, high oxygenates and low calorific value. In this study, pyrolysis oil obtained from lignocellulosic fibers of <i>Syzygium cumini</i> leaf litter was upgraded in a fixed-bed reactor at 450 °C and 10 °C/min heating rate using a synthesized nickel-infused zeolite catalyst. Characterization of the Nickel/Zeolite Socony Mobil-5 (Ni/ZSM-5) catalyst using EDXRF showed an abundance of NiO (31.05%), SiO (24.5%) and Al<sub>2</sub>O<sub>3</sub> (2.5%). Physicochemical and ultimate properties of the oil including viscosity, density, acid value, calorific value, carbon, hydrogen, oxygen, sulfur and nitrogen contents fell within ASTM standards for pyrolysis oils and conventional hydrocarbon diesel. The upgraded oil was mainly composed of carboxylic acid esters (30.69%), phenols (21.3%), 5-methyl-2-furancarboxyaldehyde (14.12%), hydrocarbons (14%) and 1,5-dimethyl-1-H-imidazole (8.3%). These findings underscore the potential of Ni/ZSM-5 catalyst as a viable tool for converting pyrolysis oil to biofuel, thereby contributing to sustainable energy solutions.</p></div>","PeriodicalId":513,"journal":{"name":"Chemical Papers","volume":"79 9","pages":"6117 - 6127"},"PeriodicalIF":2.5,"publicationDate":"2025-06-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144918559","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Chemical PapersPub Date : 2025-06-22DOI: 10.1007/s11696-025-04163-9
Haram Inam, Arjumand Iqbal Durrani, Rahila Huma, Fouzia Hussain
{"title":"Leaves extracts-driven synthesis of ZnO nanoparticles for enhanced adsorption of methyl red dye","authors":"Haram Inam, Arjumand Iqbal Durrani, Rahila Huma, Fouzia Hussain","doi":"10.1007/s11696-025-04163-9","DOIUrl":"10.1007/s11696-025-04163-9","url":null,"abstract":"<div><p>Textile dye contamination in wastewater poses a significant ecological threat, demanding urgent attention from industrialists and scientists. This study explores an environmentally benign method to manufacture zinc oxide nanoparticles (ZnO-NPs) using a quick, affordable, and sustainable method with aqueous extracts of <i>Mangifera indica</i> and <i>Syzygium cumini</i> leaves (1:1) to remove methyl red dye (MR). Characterization of the synthesized ZnO-NPs was conducted using UV–Vis, FTIR, DLS, zeta potential, SEM, EDX, BET, and X-ray diffraction (XRD). The XRD spectra, aligned with JCPDS card (00-005-0664), confirmed the presence of ZnO-NPs, with average crystallite sizes of 11.83 nm and 19.09 nm determined by the Scherrer formula and W–H technique, respectively. SEM analysis revealed an average size of 41.78 nm. The batch adsorption study revealed that MR removal efficiency using ZnO-NPs depends on pH (1–8), initial dye concentration (5–60 mg/L), contact time (0–30 min), and adsorbent dose (2–20 mg). The highest MR removal rate was 99% after 10 min at pH 4 in 20 mg/L solution. Kinetic analysis aligned with the pseudo-second-order model, supported by four statistical error models, while adsorption isotherm findings fit the Langmuir isotherm, exhibiting an adsorption capacity of 66.4 mg/g. Thermodynamic analysis indicated that MR dye adsorption on ZnO is an endothermic (∆<i>H</i>° > 0) and spontaneous (∆<i>G</i>° < 0) process. The ZnO nanoparticles exhibited promising antibacterial activity, with desorption data and cost analysis confirming their stability, reusability, and feasibility over multiple cycles. This study highlights the intriguing efficacy of green ZnO nanoparticles for effectively removing dyes from textile waste streams.</p><h3>Graphical abstract</h3>\u0000<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":513,"journal":{"name":"Chemical Papers","volume":"79 9","pages":"5921 - 5940"},"PeriodicalIF":2.5,"publicationDate":"2025-06-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144918440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Chemical PapersPub Date : 2025-06-21DOI: 10.1007/s11696-025-04146-w
Bassam Shaaban Mohammed, Mohamed A. Abdel-Lateef, Eman Alzahrani
{"title":"As spectrofluorimetric resonance Rayleigh scattering technique for determination of antianxiety drug with red acidic dye, application for dosage form and human plasma","authors":"Bassam Shaaban Mohammed, Mohamed A. Abdel-Lateef, Eman Alzahrani","doi":"10.1007/s11696-025-04146-w","DOIUrl":"10.1007/s11696-025-04146-w","url":null,"abstract":"<div><p>The resonant Rayleigh scattering (RLS) spectroscopy technique was used to examine the interaction between venlafaxine hydrochloride (VNX) and red dye, also known as EOSIN Y. Eosin and VNX interacted in an acidic buffer solution to generate an ion pair, which was accompanied by an increase in RLS intensity recorded at 315 nm. Furthermore, estimates were made for the reaction’s change in free energy and the stability constant. Using EOSIN Y as a probe, a novel approach was created based on this interaction for the sensitive VNX analysis. The outcomes showed that this strategy had good selectivity even when concomitant chemicals were present. Over the range of 30–800 ng mL<sup>−1</sup> for VNX, the scattering intensity (Δ<i>I</i><sub>RLS</sub>) was linearly dependent on the concentration of VNX. The techniques could be appropriately applied to the VNX analysis in spiked human plasma and pharmaceutical formula since they were validated in accordance with ICH guidelines.</p></div>","PeriodicalId":513,"journal":{"name":"Chemical Papers","volume":"79 8","pages":"5565 - 5574"},"PeriodicalIF":2.5,"publicationDate":"2025-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145167308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Chemical PapersPub Date : 2025-06-21DOI: 10.1007/s11696-025-04177-3
Abdur Rehman, Maryam Naveed, Muhammad Irfan Siyal
{"title":"Low-temperature dyeing of recycled polyester fibers using COUMARIN as eco-friendly carrier","authors":"Abdur Rehman, Maryam Naveed, Muhammad Irfan Siyal","doi":"10.1007/s11696-025-04177-3","DOIUrl":"10.1007/s11696-025-04177-3","url":null,"abstract":"<div><p>In this research, recycled polyester fabric was dyed using agro-sourced eco-friendly natural carrier called coumarin at dyeing process temperature of 100℃. The carrier modified glass transition temperature of recycled polyester fibers resulting in significant coloration process compared with synthetic carrier. Varying the dyeing process parameters such as carrier concentration, dye concentration, and low- and high-molecular-weight disperse dyes showed significant improvement yielding color with coumarin. The high concentration of the natural carrier resulted in significant penetration of the dye molecules proving a promising competitor of synthetic carrier. The overall color fastness properties with respect to rubbing, washing, light, perspiration were obtained from very good to excellent as well as prominent k/s value for the dyed fabric at 4 g/l after carrier dyeing at 100℃. Coumarin does not pollute water and can replace the need for use of synthetic carrier providing environment friendly process for dyeing of recycled polyester fabric.</p><h3>Graphical abstract</h3><div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":513,"journal":{"name":"Chemical Papers","volume":"79 9","pages":"6103 - 6115"},"PeriodicalIF":2.5,"publicationDate":"2025-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144918432","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"HPLC–DAD phenolic profile, antioxidant, anti-inflammatory, and anticancer activities of Bryonia cretica subsp. dioica (Jacq.) Tutin. (Cucurbitaceae)","authors":"Khadidja Belhouala, Cansu Korkmaz, Meltem Taş-Küçükaydin, Selçuk Küçükaydin, Mehmet Emin Duru, Bachir Benarba","doi":"10.1007/s11696-025-04169-3","DOIUrl":"10.1007/s11696-025-04169-3","url":null,"abstract":"<div><p>The present study aimed to evaluate the anticancer, antioxidant, and anti-inflammatory activities of <i>Bryonia cretica</i> subsp<i>. dioica</i> (Jacq.) Tutin. <i>(B. dioica)</i> aqueous and methanolic extracts along with the exploration of their phenolic metabolites. The phenolic profile was established using HPLC–DAD. Phosphomolybdate, DPPH, FRAP, and hydrogen peroxide (H<sub>2</sub>O<sub>2</sub>) assays were used to evaluate the antioxidant activity. Furthermore, the anti-inflammatory potential was investigated through human red blood cells (HRBC) stabilization, albumin denaturation, and proteinase inhibition assays, while the anticancer efficiency was estimated through cell viability assay (MTT) on four different cell lines. Our results showed that 16 phenolic metabolites were identified in both extracts with predominance of rosmarinic acid, coumarin, quercetin, rutin, and caffeic acid. Moreover, <i>B. dioica</i> extracts exhibited an important biological activity. Indeed, the aqueous extract of <i>B. dioica</i> roots showed the highest free radical-scavenging capacity of 57.36 ± 0.91% and IC<sub>50</sub> of 385 ± 0.04 μg/mL. Whereas, the methanolic extract exhibited the best HRBC membrane stabilization percentage (69.90 ± 0.17%) at 500 μg/mL. Surprisingly, <i>B. dioica</i> extracts showed important anticancer activity against HT-29 cell line recording an IC<sub>50</sub> values of 1.45 ± 0.016 and 1.50 ± 0.042 log<sub>10</sub> µg/mL for the methanolic and aqueous extracts, respectively. Keeping in view the promising biological potential of this specie, we suggest <i>B. dioica</i> roots as potential source of natural bioactive molecules possessing antioxidant, anti-inflammatory, and especially anticancer effect. </p></div>","PeriodicalId":513,"journal":{"name":"Chemical Papers","volume":"79 9","pages":"6011 - 6024"},"PeriodicalIF":2.5,"publicationDate":"2025-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144918431","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}