BioMedicine最新文献_第3页

Knowledge regarding COVID-19 among the teaching professionals of Karnataka 卡纳塔克邦教学专业人员对 COVID-19 的了解情况

BioMedicine Pub Date : 2024-01-27 DOI: 10.51248/.v43i6.3003

Sahana Maben, Audrey Madonna DCruz

{"title":"Knowledge regarding COVID-19 among the teaching professionals of Karnataka","authors":"Sahana Maben, Audrey Madonna DCruz","doi":"10.51248/.v43i6.3003","DOIUrl":"https://doi.org/10.51248/.v43i6.3003","url":null,"abstract":"Introduction and Aim: Around the world, the COVID -19 pandemic has had an impact on the lives of more than 349 million individuals. Educational institutions especially the faculty and students have an important role in preventing the spread of COVID-19 virus. The objective of the study was to assess the knowledge regarding COVID19 among the teaching professionals of Karnataka.\u0000 \u0000Material and Methods: A self-administered, pretested questionnaire was used to assess the knowledge regarding COVID 19 among the teaching Professionals of Karnataka State, India. Descriptive statistics were used in the present study to report the frequency/ percentage of responses for individual items. The total score was calculated for individual participants. Chi-square test was used to analyse the total scores with respect to the socio demographic variables.\u0000 \u0000Results: Sixty teachers participated in the survey, with all of them being aware of the COVID-19 pandemic. The majority (96.7%) acknowledged person-to-person transmission, and 90% were informed about the absence of a COVID-19 vaccine. Regarding symptoms, 95% recognized fever, cough, and breathing difficulty. Additionally, 98.3% identified social distancing, wearing masks, and frequent handwashing as preventive measures, while 96.7% advocated avoiding handshakes entirely.\u0000 \u0000Conclusion: The knowledge among teaching professionals in Karnataka regarding COVID19 was good.","PeriodicalId":512726,"journal":{"name":"BioMedicine","volume":"55 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140491988","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Molecular characterization of carbapenemase production in clinical isolates of Klebsiella species isolated in a tertiary care hospital 一家三甲医院临床分离的克雷伯氏菌产生碳青霉烯酶的分子特征

BioMedicine Pub Date : 2024-01-27 DOI: 10.51248/.v43i6.2515

Madhulika Bansal, Anita Pandey, Kalpana Chauhan, Peetam Singh

{"title":"Molecular characterization of carbapenemase production in clinical isolates of Klebsiella species isolated in a tertiary care hospital","authors":"Madhulika Bansal, Anita Pandey, Kalpana Chauhan, Peetam Singh","doi":"10.51248/.v43i6.2515","DOIUrl":"https://doi.org/10.51248/.v43i6.2515","url":null,"abstract":"Introduction and Aim: Emergence of resistance to carbapenems in clinical isolates of Klebsiella species is a matter of concern. This prospective study was carried out to determine the prevalence of carbapenem resistance in clinical isolates of Klebsiella species phenotypically and to confirm for the presence of bla NDM (New Delhi metallo-b-lactamase) and bla KPC (Klebsiella pneumoniae carbapenemase) genes in these isolates.\u0000 \u0000Materials and Methods: The 336 clinical isolates of Klebsiella species were tested for carbapenemase production by phenotypic tests; the Modified Hodge Test (MHT) and Combined Disc Test (CDT). The carbapenemase producers were further confirmed for presence of bla NDM and bla KPC genes using polymerase chain reaction (PCR). \u0000 \u0000Results: Resistance to carbapenem was seen in 34.52% of clinical isolates of Klebsiella species and majority of these isolates were from inpatient units (59.23%) of the Hospital. Maximum cases were seen in males (63.69%) and the positivity rate was high in > 61 years of age (27.08%). On genotypic characterization, bla NDM was the predominant (15.52%) gene detected as compared to bla KPC (10.34%) gene. However, these 2 genes could not be detected in some isolates suggesting other genes responsible for carbapenem resistance.\u0000 \u0000Conclusion: Emergence of resistance to carbapenem is a matter of concern. There was predominance of bla NDM gene in our hospital. Timely and accurate detection of resistance and rational use of second and third-line antibiotics would allow the early initiation of treatment for better patient outcome.","PeriodicalId":512726,"journal":{"name":"BioMedicine","volume":"6 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140492524","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The role of glycemic status in onset of microalbuminuria in patients with diabetes mellitus 血糖状况在糖尿病患者出现微量白蛋白尿中的作用

BioMedicine Pub Date : 2024-01-27 DOI: 10.51248/.v43i6.2725

Romy. W. Marshnil, Archana Mony, Ganesh G., Aaron Vetha Jose J.

{"title":"The role of glycemic status in onset of microalbuminuria in patients with diabetes mellitus","authors":"Romy. W. Marshnil, Archana Mony, Ganesh G., Aaron Vetha Jose J.","doi":"10.51248/.v43i6.2725","DOIUrl":"https://doi.org/10.51248/.v43i6.2725","url":null,"abstract":"Introduction and Aim: Diabetic nephropathy is a major microvascular complication in diabetic patients. Microalbuminuria when detected early, helps to delay progression to proteinuria and overt diabetic nephropathy. This study aims to find out the role of glycaemic control and development of microalbuminuria in type -2 diabetes.\u0000 \u0000Materials and Methods: This study was done at a South Indian tertiary care centre. Our case control study included 100 subjects with diabetes as cases and 100 age and sex-matched healthy individuals without diabetes as the controls. Blood samples were collected from both groups to assess fasting and post prandial blood sugar levels, as well as HbA1c levels. Urine samples were also analysed for microalbumin using midstream early morning samples. Our data was analysed using statistical methods such as Chi square test, unpaired Student’s t-tests, and linear regression method.\u0000 \u0000Results: The results displayed a striking rise in the average levels of urine microalbumin in individuals with diabetes, as compared to those without the condition. Furthermore, there was a considerable escalation in urine microalbumin levels observed with longer durations of diabetes. Additionally, there was a strong and significant connection between HbA1c and urine microalbumin levels amongst patients diagnosed with type-2 diabetes.\u0000 \u0000Conclusion: It is vital to screen for microalbuminuria in individuals with type-2 diabetes mellitus at an early stage, in order to lower the likelihood of developing nephropathy in diabetes and end-stage kidney failure. Additionally, suboptimal glycemic management in type-2 diabetes significantly raises the chances of developing microalbuminuria.","PeriodicalId":512726,"journal":{"name":"BioMedicine","volume":"20 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140492197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

End of care and caregiver-Dyadic death 护理结束和护理人员--慢性病死亡

BioMedicine Pub Date : 2024-01-21 DOI: 10.51248/.v43i6.3990

Chaitra Pai, Ullasa Shetty, Shodhan Rao Pejavar, Parinita, Suhel Shetty

引用次数: 0

Correlation between serum cortisol levels and practice of yoga and meditation in medical students 医学生血清皮质醇水平与瑜伽和冥想练习之间的相关性

BioMedicine Pub Date : 2024-01-21 DOI: 10.51248/.v43i6.3551

Kavitha M.M., C. S H, Anagha V.S., Kashinakunti S.V.

{"title":"Correlation between serum cortisol levels and practice of yoga and meditation in medical students","authors":"Kavitha M.M., C. S H, Anagha V.S., Kashinakunti S.V.","doi":"10.51248/.v43i6.3551","DOIUrl":"https://doi.org/10.51248/.v43i6.3551","url":null,"abstract":"Introduction and Aim: Recent year’s yoga has gained a very good response in today’s world as one of the natural methods to reduce stress. Yoga acts as an adjuvant to many kinds of treatment for various stress-related disorders. To meet the modern lifestyle full of tension, stress and challenges and to gain all round personality development yoga is mandatory. With this background current study was carried out, to estimate and compare the serum cortisol levels and heart rate variability and also to evaluate the relationship between serum cortisol levels, heart rate variability before and after yoga and meditation practice for six weeks in study group and control group in first year medical students.\u0000 \u0000Material and Methods: Informed consent was obtained before the start of the study. The current study was a quasi-experimental study with 80 subjects, 40 medical students as cases which is an interventional group and 40 students as a control group. For a period of six weeks, yoga and meditation practice was given to an interventional group by a yoga master daily for one hour.\u0000 \u0000Results: After practicing yoga regularly and promptly, cases showed decrease in serum cortisol levels and improvement in HRV parameters, frequency domain values like RMSSD increased and among time domain values HF increased and LF, LF/HF ratio decreased. There was no change observed in serum cortisol levels and HRV parameters of the control group. We observed statistically significant negative correlation between serum cortisol levels and HRV parameters in the interventional group after yoga practice. \u0000 \u0000Conclusion: Hence, incorporation of yoga and meditation as part of our lifestyle in medical students will help them to cope up with day-to-day stress during their study period.","PeriodicalId":512726,"journal":{"name":"BioMedicine","volume":"217 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140501286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of mangiferin and giloy herbal extract: Future home remedy for glycemic control by insulin secretion in type 2 diabetes mellitus 芒果苷和吉罗伊草药提取物的效果：通过胰岛素分泌控制 2 型糖尿病患者血糖的未来家庭疗法

BioMedicine Pub Date : 2024-01-21 DOI: 10.51248/.v43i6.3989

Gurupadagoud N. Patil, S. Walvekar, Bhimashetty S. Patil, Basavaraj S. Aski, B. Devarnavadagi

{"title":"Effect of mangiferin and giloy herbal extract: Future home remedy for glycemic control by insulin secretion in type 2 diabetes mellitus","authors":"Gurupadagoud N. Patil, S. Walvekar, Bhimashetty S. Patil, Basavaraj S. Aski, B. Devarnavadagi","doi":"10.51248/.v43i6.3989","DOIUrl":"https://doi.org/10.51248/.v43i6.3989","url":null,"abstract":"Introduction: Diabetes mellitus is a metabolic disorder that has a number of allopathic treatments in practice which are having adverse side effects. Mangiferin and giloy are the important Ayurvedic medications. Both have effective control over diabetes glycemic status. It is possible that the treatment of certain herbal remedies led to an increase in intracellular Ca2+ levels or that glucose-stimulated insulin secretion was enhanced through activating glucose transporter-2 (GLUT-2) receptors. In our work, we rigorously examined the chemical and biological properties of giloy and mangiferin. Clinical study on the effect of mangiferin and giloy combined extract solution in type 2 diabetic subjects and determine the level of Fasting Blood sugar, insulin and HbA1c in type 2 diabetic subjects before and after therapy.\u0000 \u0000Materials and Methods: A randomized cross-sectional study was conducted on type 2 diabetic subjects. Study design with group 1 diabetic subjects (n=45) of FBS less than or equal to 160 mg/dl) and diabetic subjects group 2 (n=49) of FBS more than 160 mg/dl were included with regular antidiabetic drugs; in addition, for the period 30 days, twice a day, 500 mg mangiferin and 500 mg giloy extract was given to group 1 and group 2. The difference between the groups was calculated using the t-test and Mann-Whitney U test.\u0000 \u0000Results: It is evident from the statistical data a significant change seen in HbA1c levels , FBS levels and insulin values while comparing group 1 and group 2 diabetic subjects. However, in group 1 and group 2 creatinine levels did not show much change.\u0000 \u0000Conclusion: Our study findings indicate that mangiferin and giloy extract is a better regime for the effective glycaemic control by an increase in insulin levels. Further, herbal leaf extract is a good natural source and cost-effective with no adverse side effects.","PeriodicalId":512726,"journal":{"name":"BioMedicine","volume":"204 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140501094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of blood mercury levels and a few biochemical marker levels in obese car painters of Iraq 对伊拉克肥胖汽车油漆工血液中汞水平和一些生化标志物水平的评估

BioMedicine Pub Date : 2024-01-21 DOI: 10.51248/.v43i6.3549

Nada K. Jawad, Ahmad T. Numan, Yossra K. Hanoon

{"title":"Evaluation of blood mercury levels and a few biochemical marker levels in obese car painters of Iraq","authors":"Nada K. Jawad, Ahmad T. Numan, Yossra K. Hanoon","doi":"10.51248/.v43i6.3549","DOIUrl":"https://doi.org/10.51248/.v43i6.3549","url":null,"abstract":"Introduction and Aim: A greater total blood mercury level is associated with obesity; the present study sought to evaluate the association between blood mercury levels and other biological indicators related to.\u0000 \u0000Materials and Methods: The study population included 25 car painters and 25 healthy participants. The height and weight of each participant was recorded and their BMI calculated. Blood drawn from each participant was assessed for their serum levels of mercury and a few other biochemical markers such as TNF-alpha, MDA, Visvatin, Insulin, and Vitamin-D. The data obtained was subjected to statistical analysis.\u0000 \u0000Results: Compared to healthy controls, the mean levels of mercury in the blood as well as other biochemical indicators were found to be greater. On the other hand, the amount of vitamin D was discovered to be lower than average in the control group. A higher quantity of mercury in the blood was shown to be associated with abdominal obesity, as indicated by the findings.\u0000 \u0000Conclusion: Obesity increases the risk of mercury toxicity in car painters and is linked to higher TNF-alpha, visfatin, and MDA levels, as well as lower vitamin D levels.","PeriodicalId":512726,"journal":{"name":"BioMedicine","volume":"63 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140501452","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Detection of the effect of synthetic siRNA on efflux pump MexA gene expression and antibiotic resistance in clinical isolates of Pseudomonas aeruginosa 检测合成 siRNA 对铜绿假单胞菌临床分离物中外排泵 MexA 基因表达和抗生素耐药性的影响

BioMedicine Pub Date : 2024-01-21 DOI: 10.51248/.v43i6.3718

Farah M. Al-Qurashi, Wathiq Abbas Al-Draghi

{"title":"Detection of the effect of synthetic siRNA on efflux pump MexA gene expression and antibiotic resistance in clinical isolates of Pseudomonas aeruginosa","authors":"Farah M. Al-Qurashi, Wathiq Abbas Al-Draghi","doi":"10.51248/.v43i6.3718","DOIUrl":"https://doi.org/10.51248/.v43i6.3718","url":null,"abstract":"Introduction and Aim: Pseudomonas aeruginosa is a nosocomial infection with an ability to develop high levels of antibiotic resistance. The efflux pump system is one of the mechanisms that is linked to multidrug resistance in P. aeruginosa. In this study, we employed siRNA loaded on gold nanoparticles against the MexA efflux pump gene to decrease the MexA gene expression in P. aeruginosa and estimated antibiotic resistance after gene silencing.\u0000 \u0000Materials and Methods: This study examined four strains of P. aeruginosa isolated from patients in various hospitals in Baghdad. Bacteria isolated were identified by biochemical tests and Vitek compact 2 system. Single-stranded siRNA (33bp) designed in this study was loaded onto gold nanoparticles (AuNPls). Detection of the MexA gene was carried out by conventional PCR technique. The expression of MexA gene was examined by qRT-PCR in order to determine if the siRNA have impacted on MexA gene expression and on the antibiotic resistance in\u0000\u0000 aeruginosa\u0000\u0000 \u0000Results: This study showed that the mRNA expression level of the MexA gene exhibited a decrease in fold change CT -2 in P. aeruginosa (isolates numbers 67, 66,49, and PDR(5p)) when examined in vitro. The specific fold change values observed were (0.202, 0.040, 0.063, and 0.163) respectively. The resistance percentages of antibiotics tested was observed to increase after MexA gene silencing.\u0000 \u0000Conclusion: Targeting the MexA gene with synthetic siRNA may be a unique approach to diminish P. aeruginosa resistance to antibiotics. However, many unexpected consequences may occur when utilizing any genetic manipulation in bacteria.","PeriodicalId":512726,"journal":{"name":"BioMedicine","volume":"150 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140501249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Anatomical and histological assessment of Arabic gum administration on visceral organs of diabetic rats 服用阿拉伯树胶对糖尿病大鼠内脏器官的解剖学和组织学评估

BioMedicine Pub Date : 2024-01-21 DOI: 10.51248/.v43i6.3454

Shurooq H. Majeed Alnassiri, Muna S. Rashid, Huda A. Hameed

{"title":"Anatomical and histological assessment of Arabic gum administration on visceral organs of diabetic rats","authors":"Shurooq H. Majeed Alnassiri, Muna S. Rashid, Huda A. Hameed","doi":"10.51248/.v43i6.3454","DOIUrl":"https://doi.org/10.51248/.v43i6.3454","url":null,"abstract":"Introduction and Aim: This century has seen a rise in the prevalence of diabetes mellitus, and since medications pose a number of risks and adverse effects, researchers have been experimenting with a variety of natural materials, including herbs. One among the herbs is Arabic gum which is considered beneficial in treating diabetes. In this study, we investigated the anatomical and histological effect of Arabic gum treatment in diabetes-induced rats when administered at different concentrations.\u0000 \u0000Materials and Methods In this study, albino rats were divided into four experimental groups: control, alloxan administered, alloxan and Arabic gum (5%) administered, and alloxan and Arabic gum (10%) administered. Following the experimental period, the four groups of animals were sacrificed and their anatomical and histopathological changes were studied.\u0000 \u0000Results: This study showed that alloxan induced diabetes caused liver, kidney and lung injuries. The groups that received alloxan with Arabic gum at concentrations 5 % and 10% exacerbated the organ damage. Several anatomical changes of the visceral organs were seen in relation to animals in the control group. Morphologically, groups that received Alloxan and Arabic gum had white spot lesions on the surfaces of the liver kidney and lungs. Histopathological changes were also observed in the liver, kidney and lungs of the animals when compared to controls. \u0000 \u0000Conclusion: Organs such as the liver, kidneys, and lungs were found to be damaged in alloxan-induced diabetic rats. The administration of Arabic gum at concentrations of 5% and 10% does not stop the damage to these organs. ","PeriodicalId":512726,"journal":{"name":"BioMedicine","volume":"70 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140501307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Association between TPO gene polymorphisms with susceptibility to hyperthyroidism TPO 基因多态性与甲状腺功能亢进症易感性之间的关系

BioMedicine Pub Date : 2024-01-21 DOI: 10.51248/.v43i6.3499

Sarah T. Al-Mofarji, Hameed M. Jasim, Sanad B. Mohammed

{"title":"Association between TPO gene polymorphisms with susceptibility to hyperthyroidism","authors":"Sarah T. Al-Mofarji, Hameed M. Jasim, Sanad B. Mohammed","doi":"10.51248/.v43i6.3499","DOIUrl":"https://doi.org/10.51248/.v43i6.3499","url":null,"abstract":"Introduction and Aim: Hyperthyroidism is a disorder characterized by excessively high amounts of tri-iodothyronine and thyroxine in the bloodstream. TPO is a thyroid-specific antigen. TPO gene mutations affect thyroid hormone synthesis, causing full or partial iodide organification abnormalities. In this study, we aimed to look at the single nucleotide polymorphisms (SNPs) in the TPO gene and find possible relation of these SNPs to the development or prognosis of hyperthyroidism.\u0000 \u0000Materials and Methods: Blood samples were collected from hyperthyroid patients (n=75) and healthy individuals (n=25). The concentration of triiodothyronine (T3), Tetra-iodothyronine (T4), and thyroid stimulating hormone (TSH) were estimated in all samples. The autoantibodies TPOAbs and TR-Ab levels were measured using the ELISA assay. The extracted genomic DNA from blood of participants was investigated for polymorphism in the SNPs rs1126799, rs1126797, and rs732609 within the TPO gene. Statistical methods were used to evaluate the association between the TPO SNPs studied to hyperthyroidism susceptibility.\u0000 \u0000Results: No significant correlation was observed between the SNPs studied and prognosis of hyperthyroidism. However, it was found that hyperthyroid patients carrying the TPO rs1126799 T allele (CT + CC genotypes) had significantly higher serum levels of TPOAb compared to those with the TT genotype (P<0.01). Similarly, hyperthyroid patients with the TPO rs1126797 C allele (CT + TT genotypes) and TPO rs732609 A allele (CA + AA genotypes) exhibited significantly elevated levels of TPOAbs compared to individuals with the CC genotype and AA genotype, respectively (P<0.01).\u0000 \u0000Conclusion: There was no correlation between the TPO rs1126799, rs1126797, and rs732609 polymorphisms with the occurrence of hyperthyroidism in the Iraqi population. However, TPO rs2071400 and rs2048722 polymorphisms were found to be correlated to serum levels of TPOAb.","PeriodicalId":512726,"journal":{"name":"BioMedicine","volume":"5 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140501401","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0