International Journal of Computer Assisted Radiology and Surgery最新文献

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Optimization of percutaneous intervention robotic system for skin insertion force. 优化经皮介入机器人系统的皮肤插入力。
IF 2.3 3区 医学
International Journal of Computer Assisted Radiology and Surgery Pub Date : 2025-02-01 Epub Date: 2024-11-08 DOI: 10.1007/s11548-024-03274-0
Benfang Duan, Biao Jia, Cheng Wang, Shijia Chen, Jun Xu, Gao-Jun Teng
{"title":"Optimization of percutaneous intervention robotic system for skin insertion force.","authors":"Benfang Duan, Biao Jia, Cheng Wang, Shijia Chen, Jun Xu, Gao-Jun Teng","doi":"10.1007/s11548-024-03274-0","DOIUrl":"10.1007/s11548-024-03274-0","url":null,"abstract":"<p><strong>Purpose: </strong>Percutaneous puncture is a common interventional procedure, and its effectiveness is influenced by the insertion force of the needle. To optimize outcomes, we focus on reducing the peak force of the needle in the skin, aiming to apply this method to other tissue layers.</p><p><strong>Methods: </strong>We developed a clinical puncture system, setting and measuring various variables. We analyzed their effects, introduced admittance control, set thresholds, and adjusted parameters. Finally, we validated these methods to ensure their effectiveness.</p><p><strong>Results: </strong>Our system meets application requirements. We assessed the impact of various variables on peak force and validated the effectiveness of the new method. Results show a reduction of about 50% in peak force compared to the maximum force condition and about 13% compared to the minimum force condition. Finally, we summarized the factors to consider when applying this method.</p><p><strong>Conclusion: </strong>To achieve peak force suppression, initial puncture variables should be set based on the trends in variable impact. Additionally, the factors of the new method should be introduced using these initial settings. When selecting these factors, the characteristics of the new method must also be considered. This process will help to better optimize peak puncture force.</p>","PeriodicalId":51251,"journal":{"name":"International Journal of Computer Assisted Radiology and Surgery","volume":" ","pages":"345-355"},"PeriodicalIF":2.3,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142607345","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Simulation of thoracic endovascular aortic repair in a perfused patient-specific model of type B aortic dissection. 在 B 型主动脉夹层患者特异性灌注模型中模拟胸腔内血管主动脉修复术。
IF 2.3 3区 医学
International Journal of Computer Assisted Radiology and Surgery Pub Date : 2025-02-01 Epub Date: 2024-06-07 DOI: 10.1007/s11548-024-03190-3
Lukas Mohl, Roger Karl, Matthias N Hagedorn, Armin Runz, Stephan Skornitzke, Malte Toelle, C Soeren Bergt, Johannes Hatzl, Christian Uhl, Dittmar Böckler, Katrin Meisenbacher, Sandy Engelhardt
{"title":"Simulation of thoracic endovascular aortic repair in a perfused patient-specific model of type B aortic dissection.","authors":"Lukas Mohl, Roger Karl, Matthias N Hagedorn, Armin Runz, Stephan Skornitzke, Malte Toelle, C Soeren Bergt, Johannes Hatzl, Christian Uhl, Dittmar Böckler, Katrin Meisenbacher, Sandy Engelhardt","doi":"10.1007/s11548-024-03190-3","DOIUrl":"10.1007/s11548-024-03190-3","url":null,"abstract":"<p><strong>Purpose: </strong>Complicated type B Aortic dissection is a severe aortic pathology that requires treatment through thoracic endovascular aortic repair (TEVAR). During TEVAR a stentgraft is deployed in the aortic lumen in order to restore blood flow. Due to the complicated pathology including an entry, a resulting dissection wall with potentially several re-entries, replicating this structure artificially has proven to be challenging thus far.</p><p><strong>Methods: </strong>We developed a 3d printed, patient-specific and perfused aortic dissection phantom with a flexible dissection flap and all major branching vessels. The model was segmented from CTA images and fabricated out of a flexible material to mimic aortic wall tissue. It was placed in a pulsatile hemodynamic flow loop. Hemodynamics were investigated through pressure and flow measurements and doppler ultrasound imaging. Surgeons performed a TEVAR intervention including stentgraft deployment under fluoroscopic guidance.</p><p><strong>Results: </strong>The flexible aortic dissection phantom was successfully incorporated in the hemodynamic flow loop, a systolic pressure of 112 mmHg and physiological flow of 4.05 L per minute was reached. Flow velocities were higher in true lumen with a up to 35.7 cm/s compared to the false lumen with a maximum of 13.3 cm/s, chaotic flow patterns were observed on main entry and reentry sights. A TEVAR procedure was successfully performed under fluoroscopy. The position of the stentgraft was confirmed using CTA imaging.</p><p><strong>Conclusions: </strong>This perfused in-vitro phantom allows for detailed investigation of the complex inner hemodynamics of aortic dissections on a patient-specific level and enables the simulation of TEVAR procedures in a real endovascular operating environment. Therefore, it could provide a dynamic platform for future surgical training and research.</p>","PeriodicalId":51251,"journal":{"name":"International Journal of Computer Assisted Radiology and Surgery","volume":" ","pages":"391-404"},"PeriodicalIF":2.3,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11807923/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141285347","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hybrid registration of the fibula for electromagnetically navigated osteotomies in mandibular reconstructive surgery: a phantom study. 下颌骨重建手术中电磁导航截骨术的腓骨混合注册:一项模型研究。
IF 2.3 3区 医学
International Journal of Computer Assisted Radiology and Surgery Pub Date : 2025-02-01 Epub Date: 2024-11-25 DOI: 10.1007/s11548-024-03282-0
L M N Aukema, A F de Geer, M J A van Alphen, W H Schreuder, R L P van Veen, T J M Ruers, F J Siepel, M B Karakullukcu
{"title":"Hybrid registration of the fibula for electromagnetically navigated osteotomies in mandibular reconstructive surgery: a phantom study.","authors":"L M N Aukema, A F de Geer, M J A van Alphen, W H Schreuder, R L P van Veen, T J M Ruers, F J Siepel, M B Karakullukcu","doi":"10.1007/s11548-024-03282-0","DOIUrl":"10.1007/s11548-024-03282-0","url":null,"abstract":"<p><strong>Purpose: </strong>In mandibular reconstructive surgery with free fibula flap, 3D-printed patient-specific cutting guides are the current state of the art. Although these guides enable accurate transfer of the virtual surgical plan to the operating room, disadvantages include long waiting times until surgery and the inability to change the virtual plan intraoperatively in case of tumor growth. Alternatively, (electromagnetic) surgical navigation combined with a non-patient-specific cutting guide could be used, requiring accurate image-to-patient registration. In this phantom study, we evaluated the accuracy of a hybrid registration method for the fibula and the additional error that is caused by navigating with a prototype of a novel non-patient-specific cutting guide to virtually planned osteotomy planes.</p><p><strong>Methods: </strong>The accuracy of hybrid registration and navigation was assessed in terms of target registration error (TRE), angular difference, and length difference of the intended fibula segments using three 3D-printed fibular phantoms with assessment points on osteotomy planes. Using electromagnetic tracking, hybrid registration was performed with point registration followed by surface registration on the lateral fibular surface. The fibula was fixated in the non-patient-specific cutting guide to navigate to planned osteotomy planes after which the accuracy was assessed.</p><p><strong>Results: </strong>Registration was achieved with a mean TRE, angular difference, and segment length difference of 2.3 ± 0.9 mm, 2.1 ± 1.4°, and 0.3 ± 0.3 mm respectively after hybrid registration. Navigation with the novel cutting guide increased the length difference (0.7 ± 0.6 mm), but decreased the angular difference (1.8 ± 1.3°).</p><p><strong>Conclusion: </strong>Hybrid registration showed to be a feasible and noninvasive method to register the fibula in phantom setup and could be used for electromagnetically navigated osteotomies with a novel non-patient-specific cutting guide. Future studies should focus on testing this registration method in clinical setting.</p>","PeriodicalId":51251,"journal":{"name":"International Journal of Computer Assisted Radiology and Surgery","volume":" ","pages":"369-377"},"PeriodicalIF":2.3,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142711739","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Real-time intraoperative ultrasound registration for accurate surgical navigation in patients with pelvic malignancies. 盆腔恶性肿瘤患者术中实时超声定位准确手术导航。
IF 2.3 3区 医学
International Journal of Computer Assisted Radiology and Surgery Pub Date : 2025-02-01 Epub Date: 2024-12-04 DOI: 10.1007/s11548-024-03299-5
M A J Hiep, W J Heerink, H C Groen, L Aguilera Saiz, B A Grotenhuis, G L Beets, A G J Aalbers, K F D Kuhlmann, T J M Ruers
{"title":"Real-time intraoperative ultrasound registration for accurate surgical navigation in patients with pelvic malignancies.","authors":"M A J Hiep, W J Heerink, H C Groen, L Aguilera Saiz, B A Grotenhuis, G L Beets, A G J Aalbers, K F D Kuhlmann, T J M Ruers","doi":"10.1007/s11548-024-03299-5","DOIUrl":"10.1007/s11548-024-03299-5","url":null,"abstract":"<p><strong>Purpose: </strong>Surgical navigation aids surgeons in localizing and adequately resecting pelvic malignancies. Accuracy of the navigation system highly depends on the preceding registration procedure, which is generally performed using intraoperative fluoroscopy or CT. However, these ionizing methods are time-consuming and peroperative updates of the registration are cumbersome. In this present clinical study, several real-time intraoperative ultrasound (iUS) registration methods have been developed and evaluated for accuracy.</p><p><strong>Methods: </strong>During laparotomy in prospectively included patients, sterile electromagnetically tracked iUS acquisitions of the pelvic vessels and bones were collected. An initial registration and five other rigid iUS registration methods were developed including real-time deep learning bone and artery segmentation of 2D ultrasound. For each registration method, the accuracy was computed as the target registration error (TRE) using pelvic lymph nodes (LNs) as targets.</p><p><strong>Results: </strong>Thirty patients were included. The mean ± SD ultrasound acquisition time was 4.2 ± 1.4 min for the pelvic bone and 4.0 ± 1.1 min for the arteries. Deep learning bone and artery ultrasound segmentation resulted in an average (centerline)Dice of 0.85 and a mean surface distance below 2 mm. In 21 patients with visible LNs, initial registration resulted in a median (interquartile range [IQR]) TRE of 7.4 (5.9-10.9) mm. For the other five methods, 2D and 3D bone registration resulted in significantly lower TREs than 2D artery, 3D artery and bifurcation registration (two-sided Wilcoxon rank-sum test p < 0.01). The real-time 2D bone registration method was most accurate with a median (IQR) TRE of 2.6 (1.3-5.7) mm.</p><p><strong>Conclusion: </strong>Real-time 2D iUS bone registration is a fast and accurate method for patient registration prior to surgical navigation and has advantages over current registration techniques. Because of the user dependency of iUS, intuitive software is crucial for optimal clinical implementation. Trial registration number ClinicalTrials.gov (No. NCT05637346).</p>","PeriodicalId":51251,"journal":{"name":"International Journal of Computer Assisted Radiology and Surgery","volume":" ","pages":"249-258"},"PeriodicalIF":2.3,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142781677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Quantitative in-vitro assessment of a novel robot-assisted system for cochlear implant electrode insertion. 对用于植入人工耳蜗电极的新型机器人辅助系统进行体外定量评估。
IF 2.3 3区 医学
International Journal of Computer Assisted Radiology and Surgery Pub Date : 2025-02-01 Epub Date: 2024-10-01 DOI: 10.1007/s11548-024-03276-y
Philipp Aebischer, Lukas Anschuetz, Marco Caversaccio, Georgios Mantokoudis, Stefan Weder
{"title":"Quantitative in-vitro assessment of a novel robot-assisted system for cochlear implant electrode insertion.","authors":"Philipp Aebischer, Lukas Anschuetz, Marco Caversaccio, Georgios Mantokoudis, Stefan Weder","doi":"10.1007/s11548-024-03276-y","DOIUrl":"10.1007/s11548-024-03276-y","url":null,"abstract":"<p><strong>Purpose: </strong>As an increasing number of cochlear implant candidates exhibit residual inner ear function, hearing preservation strategies during implant insertion are gaining importance. Manual implantation is known to induce traumatic force and pressure peaks. In this study, we use a validated in-vitro model to comprehensively evaluate a novel surgical tool that addresses these challenges through motorized movement of a forceps.</p><p><strong>Methods: </strong>Using lateral wall electrodes, we examined two subgroups of insertions: 30 insertions were performed manually by experienced surgeons, and another 30 insertions were conducted with a robot-assisted system under the same surgeons' supervision. We utilized a realistic, validated model of the temporal bone. This model accurately reproduces intracochlear frictional conditions and allows for the synchronous recording of forces on intracochlear structures, intracochlear pressure, and the position and deformation of the electrode array within the scala tympani.</p><p><strong>Results: </strong>We identified a significant reduction in force variation during robot-assisted insertions compared to the conventional procedure, with average values of 12 mN/s and 32 mN/s, respectively. Robotic assistance was also associated with a significant reduction of strong pressure peaks and a 17 dB reduction in intracochlear pressure levels. Furthermore, our study highlights that the release of the insertion tool represents a critical phase requiring surgical training.</p><p><strong>Conclusion: </strong>Robotic assistance demonstrated more consistent insertion speeds compared to manual techniques. Its use can significantly reduce factors associated with intracochlear trauma, highlighting its potential for improved hearing preservation. Finally, the system does not mitigate the impact of subsequent surgical steps like electrode cable routing and cochlear access sealing, pointing to areas in need of further research.</p>","PeriodicalId":51251,"journal":{"name":"International Journal of Computer Assisted Radiology and Surgery","volume":" ","pages":"323-332"},"PeriodicalIF":2.3,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11807918/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142332055","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A virtual patient authoring tool for transcatheter aortic valve replacement. 经导管主动脉瓣置换术的虚拟患者创作工具。
IF 2.3 3区 医学
International Journal of Computer Assisted Radiology and Surgery Pub Date : 2025-02-01 Epub Date: 2024-12-19 DOI: 10.1007/s11548-024-03293-x
Seyedsina Razavizadeh, Markus Kofler, Matthias Kunz, Joerg Kempfert, Ruediger Braun-Dullaeus, Janine Weidling, Bernhard Preim, Christian Hansen
{"title":"A virtual patient authoring tool for transcatheter aortic valve replacement.","authors":"Seyedsina Razavizadeh, Markus Kofler, Matthias Kunz, Joerg Kempfert, Ruediger Braun-Dullaeus, Janine Weidling, Bernhard Preim, Christian Hansen","doi":"10.1007/s11548-024-03293-x","DOIUrl":"10.1007/s11548-024-03293-x","url":null,"abstract":"<p><strong>Purpose: </strong>Computer-based medical training scenarios, derived from patient's records, often lack variability, modifiability, and availability. Furthermore, generating image datasets and creating scenarios is resource-intensive. Therefore, patient authoring tools for rapid dataset-independent creation of virtual patients (VPs) is a pressing need.</p><p><strong>Methods: </strong>An authoring tool and a virtual catheterization laboratory environment were developed. The tool allows customised VP generation through a real-time morphable heart model and Euroscore parameters. The generated VP can be examined inside the vCathLab using a fluoroscopy and monitoring device, both on desktop and immersive virtual reality. Seven board-certified experts evaluated the proposed method from three aspects, i.e. System Usability Scale, qualitative feedback, and its performance in VR.</p><p><strong>Results: </strong>All participants agreed that this method could provide the necessary information and is anatomically correct within an educational context. Its modifiability, variability, and simplicity were well recognised. The prototype achieved excellent usability score and considerable performance results.</p><p><strong>Conclusion: </strong>We present a highly variable VP authoring tool that enhances variability in medical training scenarios. Although this work does not aim to explore didactic aspects, the potential of using this approach in an educational context has been confirmed in our study. Accordingly, these aspects can benefit from a thorough investigation in the future. In addition, our tool can be improved to provide more realistic parameter ranges for procedure-specific cases.</p>","PeriodicalId":51251,"journal":{"name":"International Journal of Computer Assisted Radiology and Surgery","volume":" ","pages":"379-389"},"PeriodicalIF":2.3,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11807921/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142856078","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Volume and quality of the gluteal muscles are associated with early physical function after total hip arthroplasty. 臀肌的体积和质量与全髋关节置换术后早期的身体功能有关。
IF 2.3 3区 医学
International Journal of Computer Assisted Radiology and Surgery Pub Date : 2025-01-21 DOI: 10.1007/s11548-025-03321-4
Makoto Iwasa, Keisuke Uemura, Mazen Soufi, Yoshito Otake, Tomofumi Kinoshita, Tatsuhiko Kutsuna, Kazuma Takashima, Hidetoshi Hamada, Yoshinobu Sato, Nobuhiko Sugano, Seiji Okada, Masaki Takao
{"title":"Volume and quality of the gluteal muscles are associated with early physical function after total hip arthroplasty.","authors":"Makoto Iwasa, Keisuke Uemura, Mazen Soufi, Yoshito Otake, Tomofumi Kinoshita, Tatsuhiko Kutsuna, Kazuma Takashima, Hidetoshi Hamada, Yoshinobu Sato, Nobuhiko Sugano, Seiji Okada, Masaki Takao","doi":"10.1007/s11548-025-03321-4","DOIUrl":"https://doi.org/10.1007/s11548-025-03321-4","url":null,"abstract":"<p><strong>Purpose: </strong>Identifying muscles linked to postoperative physical function can guide protocols to enhance early recovery following total hip arthroplasty (THA). This study aimed to evaluate the association of preoperative pelvic and thigh muscle volume and quality with early physical function after THA in patients with unilateral hip osteoarthritis (HOA).</p><p><strong>Methods: </strong>Preoperative Computed tomography (CT) images of 61 patients (eight males and 53 females) with HOA were analyzed. Six muscle groups were segmented from CT images, and muscle volume and quality were calculated on the healthy and affected sides. Muscle quality was quantified using the mean CT values (Hounsfield units [HU]). Early postoperative physical function was evaluated using the Timed Up & Go test (TUG) at three weeks after THA. The effect of preoperative muscle volume and quality of both sides on early postoperative physical function was assessed.</p><p><strong>Results: </strong>On the healthy and affected sides, mean muscle mass was 9.7 cm<sup>3</sup>/kg and 8.1 cm<sup>3</sup>/kg, and mean muscle HU values were 46.0 HU and 39.1 HU, respectively. Significant differences in muscle volume and quality were observed between the affected and healthy sides. On analyzing the function of various muscle groups, the TUG score showed a significant association with the gluteus maximum volume and the gluteus medius/minimus quality on the affected side.</p><p><strong>Conclusion: </strong>Patients with HOA showed significant muscle atrophy and fatty degeneration in the affected pelvic and thigh regions. The gluteus maximum volume and gluteus medius/minimus quality were associated with early postoperative physical function. Preoperative rehabilitation targeting the gluteal muscles on the affected side could potentially enhance recovery of physical function in the early postoperative period.</p>","PeriodicalId":51251,"journal":{"name":"International Journal of Computer Assisted Radiology and Surgery","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143015925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Perfusion estimation from dynamic non-contrast computed tomography using self-supervised learning and a physics-inspired U-net transformer architecture. 使用自监督学习和物理启发的U-net变压器架构的动态非对比计算机断层扫描灌注估计。
IF 2.3 3区 医学
International Journal of Computer Assisted Radiology and Surgery Pub Date : 2025-01-20 DOI: 10.1007/s11548-025-03323-2
Yi-Kuan Liu, Jorge Cisneros, Girish Nair, Craig Stevens, Richard Castillo, Yevgeniy Vinogradskiy, Edward Castillo
{"title":"Perfusion estimation from dynamic non-contrast computed tomography using self-supervised learning and a physics-inspired U-net transformer architecture.","authors":"Yi-Kuan Liu, Jorge Cisneros, Girish Nair, Craig Stevens, Richard Castillo, Yevgeniy Vinogradskiy, Edward Castillo","doi":"10.1007/s11548-025-03323-2","DOIUrl":"https://doi.org/10.1007/s11548-025-03323-2","url":null,"abstract":"<p><strong>Purpose: </strong>Pulmonary perfusion imaging is a key lung health indicator with clinical utility as a diagnostic and treatment planning tool. However, current nuclear medicine modalities face challenges like low spatial resolution and long acquisition times which limit clinical utility to non-emergency settings and often placing extra financial burden on the patient. This study introduces a novel deep learning approach to predict perfusion imaging from non-contrast inhale and exhale computed tomography scans (IE-CT).</p><p><strong>Methods: </strong>We developed a U-Net Transformer architecture modified for Siamese IE-CT inputs, integrating insights from physical models and utilizing a self-supervised learning strategy tailored for lung function prediction. We aggregated 523 IE-CT images from nine different 4DCT imaging datasets for self-supervised training, aiming to learn a low-dimensional IE-CT feature space by reconstructing image volumes from random data augmentations. Supervised training for perfusion prediction used this feature space and transfer learning on a cohort of 44 patients who had both IE-CT and single-photon emission CT (SPECT/CT) perfusion scans.</p><p><strong>Results: </strong>Testing with random bootstrapping, we estimated the mean and standard deviation of the spatial Spearman correlation between our predictions and the ground truth (SPECT perfusion) to be 0.742 ± 0.037, with a mean median correlation of 0.792 ± 0.036. These results represent a new state-of-the-art accuracy for predicting perfusion imaging from non-contrast CT.</p><p><strong>Conclusion: </strong>Our approach combines low-dimensional feature representations of both inhale and exhale images into a deep learning model, aligning with previous physical modeling methods for characterizing perfusion from IE-CT. This likely contributes to the high spatial correlation with ground truth. With further development, our method could provide faster and more accurate lung function imaging, potentially expanding its clinical applications beyond what is currently possible with nuclear medicine.</p>","PeriodicalId":51251,"journal":{"name":"International Journal of Computer Assisted Radiology and Surgery","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143015924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Shape-matching-based fracture reduction aid concept exemplified on the proximal humerus-a pilot study. 以肱骨近端为例的基于形状匹配的骨折复位辅助概念-一项试点研究。
IF 2.3 3区 医学
International Journal of Computer Assisted Radiology and Surgery Pub Date : 2025-01-14 DOI: 10.1007/s11548-024-03318-5
Karen Mys, Luke Visscher, Sara Lindenmann, Torsten Pastor, Paolo Antonacci, Matthias Knobe, Martin Jaeger, Simon Lambert, Peter Varga
{"title":"Shape-matching-based fracture reduction aid concept exemplified on the proximal humerus-a pilot study.","authors":"Karen Mys, Luke Visscher, Sara Lindenmann, Torsten Pastor, Paolo Antonacci, Matthias Knobe, Martin Jaeger, Simon Lambert, Peter Varga","doi":"10.1007/s11548-024-03318-5","DOIUrl":"https://doi.org/10.1007/s11548-024-03318-5","url":null,"abstract":"<p><strong>Purpose: </strong>Optimizing fracture reduction quality is key to achieve successful osteosynthesis, especially for epimetaphyseal regions such as the proximal humerus (PH), but can be challenging, partly due to the lack of a clear endpoint. We aimed to develop the prototype for a novel intraoperative C-arm-based aid to facilitate true anatomical reduction of fractures of the PH.</p><p><strong>Methods: </strong>The proposed method designates the reduced endpoint position of fragments by superimposing the outer boundary of the premorbid bone shape on intraoperative C-arm images, taking the mirrored intact contralateral PH from the preoperative CT scan as a surrogate. The accuracy of the algorithm was tested on 60 synthetic C-arm images created from the preoperative CT images of 20 complex PH fracture cases (Dataset A) and on 12 real C-arm images of a prefractured human anatomical specimen (Dataset B). The predicted outer boundary shape was compared with the known exact solution by (1) a calculated matching error and (2) two experienced shoulder trauma surgeons.</p><p><strong>Results: </strong>A prediction accuracy of 88% (with 73% 'good') was achieved according to the calculation method and an 87% accuracy (68% 'good') by surgeon assessment in Dataset A. Accuracy was 100% by both assessments for Dataset B.</p><p><strong>Conclusion: </strong>By seamlessly integrating into the standard perioperative workflow and imaging, the intuitive shape-matching-based aid, once developed as a medical device, has the potential to optimize the accuracy of the reduction of PH fractures while reducing the number of X-rays and surgery time. Further studies are required to demonstrate the applicability and efficacy of this method in optimizing fracture reduction quality.</p>","PeriodicalId":51251,"journal":{"name":"International Journal of Computer Assisted Radiology and Surgery","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-01-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142980620","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A real-time approach for surgical activity recognition and prediction based on transformer models in robot-assisted surgery. 机器人辅助手术中基于变压器模型的手术活动实时识别与预测方法。
IF 2.3 3区 医学
International Journal of Computer Assisted Radiology and Surgery Pub Date : 2025-01-12 DOI: 10.1007/s11548-024-03306-9
Ketai Chen, D S V Bandara, Jumpei Arata
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