Veterinary Quarterly最新文献

{"title":"Predictive value of TP53 RNAscope®in situ hybridization and p53 immunohistochemistry for TP53 mutational status in canine diffuse large B-cell lymphoma.","authors":"Greta Foiani,Luca Licenziato,Laura Marconato,Antonella Fanelli,Erica Melchiotti,Claudia Zanardello,Luca Aresu,Marta Vascellari","doi":"10.1080/01652176.2024.2403453","DOIUrl":"https://doi.org/10.1080/01652176.2024.2403453","url":null,"abstract":"TP53 mutations are associated with short survival and poor treatment response in canine diffuse large B-cell lymphoma (cDLBCL). The expression of TP53 by RNAscope® in situ hybridization and p53 by immunohistochemistry (IHC) was investigated in 37 formalin-fixed paraffin-embedded cDLBCL, to assess their correlation with TP53 mutational status and to evaluate their prognostic value. TP53 was detected in all samples by RNAscope®. Ten of 37 (27%) cases expressed p53 by IHC, with highly variable percentage of positive cells. TP53 RNAscope® scores and p53 IHC results were not correlated. The expression of TP53 by RNAscope® was not influenced by its mutational status. Conversely, p53 IHC and TP53 mutations were significantly associated. p53 IHC predicted TP53 genetic mutations with high accuracy (97.3%). All TP53-mutated samples carrying missense mutations exhibited p53 expression by IHC, while all wild-type cases and a single case with frameshift insertion were negative. In univariable analysis, p53 IHC was associated with shorter time to progression (TTP) and lymphoma-specific survival (LSS). Nevertheless, in multivariable analysis, only treatment significantly affected TTP and LSS. These findings suggest p53 IHC is an accurate, cost-effective tool for predicting TP53 mutations in cDLBCL, unlike TP53 RNAscope®, though its prognostic value requires further validation.","PeriodicalId":51207,"journal":{"name":"Veterinary Quarterly","volume":"41 1","pages":"1-9"},"PeriodicalIF":6.4,"publicationDate":"2024-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142251241","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of the feasibility of equine in-vivo ultrasound technique for the medial branch of the dorsal ramus of the cervical spinal nerves","authors":"Irene Nocera, Chiara Di Franco, Benedetta Sorvillo, Benedetta Aliboni, Elena Bucchioni, Micaela Sgorbini, Giulia Sala, Simonetta Citi","doi":"10.1080/01652176.2024.2403456","DOIUrl":"https://doi.org/10.1080/01652176.2024.2403456","url":null,"abstract":"Ultrasound-guided local anaesthesia is commonly used in veterinary orthopaedics for horses. This study aimed to assess an in vivo ultrasound technique for the medial branch of the dorsal branch of ...","PeriodicalId":51207,"journal":{"name":"Veterinary Quarterly","volume":"5 1","pages":""},"PeriodicalIF":6.4,"publicationDate":"2024-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142251244","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Modulating effects of heat-killed and live Limosilactobacillus reuteri PSC102 on the immune response and gut microbiota of cyclophosphamide-treated rats","authors":"Md. Sekendar Ali, Eon-Bee Lee, Yixian Quah, Syed Al Jawad Sayem, Muhammad Aleem Abbas, Kyoungho Suk, Seung-Jin Lee, Seung-Chun Park","doi":"10.1080/01652176.2024.2344765","DOIUrl":"https://doi.org/10.1080/01652176.2024.2344765","url":null,"abstract":"In the present study, we investigated the potential immunomodulatory effects of heat-killed (hLR) and live Limosilactobacillus reuteri PSC102 (LR; formerly Lactobacillus reuteri PSC102) in RAW264.7...","PeriodicalId":51207,"journal":{"name":"Veterinary Quarterly","volume":"15 1","pages":""},"PeriodicalIF":6.4,"publicationDate":"2024-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140828228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The forecasting power of the mucin-microbiome interplay in livestock respiratory diseases","authors":"Núria Mach","doi":"10.1080/01652176.2024.2340003","DOIUrl":"https://doi.org/10.1080/01652176.2024.2340003","url":null,"abstract":"Complex respiratory diseases are a significant challenge for the livestock industry worldwide. These diseases considerably impact animal health and welfare and cause severe economic losses. One of ...","PeriodicalId":51207,"journal":{"name":"Veterinary Quarterly","volume":"39 1","pages":""},"PeriodicalIF":6.4,"publicationDate":"2024-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140568985","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Molecular analysis of Gyrovirus galga1 variants identified from the sera of dogs and cats in China","authors":"Shuqi Xu, Yuanzhuo Man, Zhengli Yu, Xin Xu, Jun Ji, Yunchao Kan, Yingzuo Bi, Qingmei Xie, Lunguang Yao","doi":"10.1080/01652176.2024.2338381","DOIUrl":"https://doi.org/10.1080/01652176.2024.2338381","url":null,"abstract":"Gyrovirus galga1 (GyVg1), a member of the Anelloviridae family and Gyrovirus genus, has been detected in chicken and human tissue samples. In this study, the DNA of GyVg1-related gyroviruses in the...","PeriodicalId":51207,"journal":{"name":"Veterinary Quarterly","volume":"49 1","pages":""},"PeriodicalIF":6.4,"publicationDate":"2024-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140568984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fatal tick-borne encephalitis virus infection in Dalmatian puppy-dogs after putative vector independent transmission","authors":"Kara L. D. Dawson, Giuliana Rosato, Simone Egloff, Carole Burgener, Anna Oevermann, Paula Grest, Monika Hilbe, Torsten Seuberlich","doi":"10.1080/01652176.2024.2338385","DOIUrl":"https://doi.org/10.1080/01652176.2024.2338385","url":null,"abstract":"In a retrospective metatranscriptomics study, we identified tick-borne encephalitis virus (TBEV) to be the causative agent for a fatal non-suppurative meningoencephalitis in a three-week-old Dalmat...","PeriodicalId":51207,"journal":{"name":"Veterinary Quarterly","volume":"55 1","pages":""},"PeriodicalIF":6.4,"publicationDate":"2024-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140603109","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dietary Chinese herbal formula supplementation improves yolk fatty acid profile in aged laying hens","authors":"Zhihua Li, Chengwen Meng, Md. Abul Kalam Azad, Wencao Lin, Jue Gui, Yadong Cui, Wei Lan, Qinghua He, Xiangfeng Kong","doi":"10.1080/01652176.2024.2319828","DOIUrl":"https://doi.org/10.1080/01652176.2024.2319828","url":null,"abstract":"Chinese herbal formula (CHF) has the potential to improve the performance of aged laying hens through integrated regulation of various physiological functions. The present study aimed to investigat...","PeriodicalId":51207,"journal":{"name":"Veterinary Quarterly","volume":"126 1","pages":""},"PeriodicalIF":6.4,"publicationDate":"2024-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139969530","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of zinc supplementation from organic and inorganic sources on growth, blood biochemical indices, and intestinal microarchitecture in broilers","authors":"Muhammad Ishtiaq Khan, Naila Chand, Shabana Naz, Rasha Alonaizan, Hong Hu, Shamsuddin Shamsi, Rifat Ullah Khan","doi":"10.1080/01652176.2023.2298491","DOIUrl":"https://doi.org/10.1080/01652176.2023.2298491","url":null,"abstract":"In poultry nutrition, zinc supplementation is typically achieved through the addition of zinc oxide or zinc sulfate to the feed. The alternative approach of organic sources utilizes an organic liga...","PeriodicalId":51207,"journal":{"name":"Veterinary Quarterly","volume":"8 1","pages":""},"PeriodicalIF":6.4,"publicationDate":"2024-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139657040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effect of epigallocatechin gallate on laying performance, egg quality, immune status, antioxidant capacity, and hepatic metabolome of laying ducks reared in high temperature condition.","authors":"Yang Liu, Xu Zhang, Yaling Yao, Xuan Huang, Chuang Li, Ping Deng, Guitao Jiang, Qiuzhong Dai","doi":"10.1080/01652176.2023.2280041","DOIUrl":"10.1080/01652176.2023.2280041","url":null,"abstract":"<p><p>Epigallocatechin gallate (EGCG) is a main component in green tea extract, which possesses multiple bioactivities. The present research studied the effects of EGCG on the laying performance, egg quality, immune status, antioxidant capacity, and hepatic metabolome of <i>Linwu</i> laying ducks reared under high temperature. A total of 180 42-w-old healthy <i>Linwu</i> laying ducks were allocated into control or EGCG-treated groups. Each treatment had 6 replicates with 15 ducks in each replicate. Diets for the two groups were basal diets supplemented with 0 or 300 mg/kg EGCG, respectively. All ducks were raised in the high temperature condition (35 ± 2 °C for 6 h from 10:00 to 16:00, and 28 ± 2 °C for the other 18 h from 16:00 to 10:00 the next day) for 21 days. Results showed that EGCG increased the egg production rate (<i>p</i> = 0.014) and enhanced the immunocompetence by improving serum levels of immunoglobulin A (<i>p</i> = 0.008) and immunoglobulin G (<i>p</i> = 0.006). EGCG also fortified the antioxidant capacity by activating superoxide dismutase (<i>p</i> = 0.012), catalase (<i>p</i> = 0.009), and glutathione peroxidase (<i>p</i> = 0.021), and increasing the level of heat-shock protein 70 (<i>p</i> = 0.003) in laying ducks' liver. At the same time, hepatic metabolomics result suggested that EGCG increased the concentration of several key metabolites, such as spermidine (<i>p</i> = 0.031), tetramethylenediamine (<i>p</i> = 0.009), hyoscyamine (<i>p</i> = 0.026), β-nicotinamide adenine dinucleotide phosphate (<i>p</i> = 0.038), and pantothenic acid (<i>p</i> = 0.010), which were involved in the metabolic pathways of glutathione metabolism, arginine and proline metabolism, β-alanine metabolism, and tropane, piperidine, and pyridine alkaloid biosynthesis. In conclusion, 300 mg/kg dietary EGCG showed protection effects on the laying ducks reared in high temperature by improving the immune and antioxidant capacities, which contributed to the increase of laying performance of ducks. The potential mechanism could be that EGCG modulate the synthesis of key metabolites and associated metabolic pathways.</p>","PeriodicalId":51207,"journal":{"name":"Veterinary Quarterly","volume":" ","pages":"1-11"},"PeriodicalIF":6.4,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11003483/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71428950","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Influence of age, habitat elevation, and distance to a thermal power plant on pathomorphological findings in the European brown hare (<i>Lepuseuropaeus</i> P.).","authors":"Darko Marinković, Renata Relić, Nada Lakić, Milan Aničić, Dejan Beuković, Vesna Davidović, Vukan Lavadinović, Zoran Popović","doi":"10.1080/01652176.2023.2273887","DOIUrl":"10.1080/01652176.2023.2273887","url":null,"abstract":"<p><p>The lifespan of the European hare (Lepus europaeus P.) is affected by a number of negative factors, including pollutants. In this paper, the individual and joint influence of age and habitat (elevation and distance from the thermal power plant - TPP) on pathomorphological findings of hares shot during three hunting seasons was investigated. Pathomorphological changes were found in 95.12% of hares. In hares up to 1 year of age, the changes were predominant in the lungs, and in older hares, in the kidneys. Degenerative changes in kidneys and liver and inflammatory changes in kidneys and lungs were considered important most in discussing the influence of chemical pollution. The proximity of TPP influenced the type of changes in the liver. A significant joint effect of age and elevation on the type of changes in the lungs of adult hares and on the heart of young hares was found. Elevation and distance from TPP had a joint effect on the occurrence of changes in the lungs, intestines, and heart in hares from the field farther from TPP. The results indicate that the hares were highly exposed to chemical pollutants that may affect their immunity, and lifespan.</p>","PeriodicalId":51207,"journal":{"name":"Veterinary Quarterly","volume":" ","pages":"1-10"},"PeriodicalIF":6.4,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11003476/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49693749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}