Stress-The International Journal on the Biology of Stress最新文献

{"title":"Inverse association between stress induced cortisol elevations and negative emotional reactivity to stress in humans.","authors":"Heather C Abercrombie, Alexandra L Barnes, Elizabeth C Nord, Anna J Finley, Estelle T Higgins, Daniel W Grupe, Melissa A Rosenkranz, Richard J Davidson, Stacey M Schaefer","doi":"10.1080/10253890.2023.2174780","DOIUrl":"10.1080/10253890.2023.2174780","url":null,"abstract":"<p><p>Greater cortisol reactivity to stress is often assumed to lead to heightened negative affective reactivity to stress. Conversely, a growing body of evidence demonstrates mood-protective effects of cortisol elevations in the context of acute stress. We administered a laboratory-based stressor, the Trier Social Stress Test (TSST), and measured cortisol and emotional reactivity in 68 adults (48 women) between the ages of 25 and 65. In accordance with our pre-registered hypothesis (https://osf.io/t8r3w) and prior research, negative affective reactivity was inversely related to cortisol reactivity assessed immediately after the stressor. We found that greater cortisol response to acute stress is associated with smaller increases in negative affect, consistent with mood-protective effects of cortisol elevations in response to acute stress.</p>","PeriodicalId":51173,"journal":{"name":"Stress-The International Journal on the Biology of Stress","volume":"26 1","pages":"2174780"},"PeriodicalIF":2.6,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9930177/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9519104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Integrating the pattern of negative emotion processing and acute stress response with childhood stress among healthy young adults.","authors":"Jianhui Wu,&nbsp;Yutong Liu,&nbsp;Liang Zhang,&nbsp;Naiyi Wang,&nbsp;Nils Kohn,&nbsp;Hongxia Duan","doi":"10.1080/10253890.2023.2195503","DOIUrl":"https://doi.org/10.1080/10253890.2023.2195503","url":null,"abstract":"<p><p>Childhood adversity might impair corticolimbic brain regions, which play a crucial role in emotion processing and the acute stress response. The dimensional model of childhood adversity proposed that deprivation and threat dimensions might associated with individuals' development through different mechanisms. However, few studies have explored the relationship between different dimensions of childhood stress, emotion processing, and acute stress reactivity despite the overlapping brain regions of the last two. With the aid of the event-related potentials technique, we explore whether negative emotion processing, which might be particularly relevant for adaptive stress responding among individuals with adverse childhood experience, mediates the relationship between dimensional childhood stress and acute stress response. Fifty-one young adults completed a free-viewing task to evaluate neural response to negative stimuli measured by late positive potential (LPP) of ERPs (Event-related potentials). On a separate day, heart rate and salivary cortisol were collected during a social-evaluative stress challenge (i.e. TSST, Trier Social Stress Test). After the TSST, the childhood trauma questionnaire was measured to indicate the level of abuse (as a proxy of threat) and neglect (as a proxy of deprivation) dimensions. Multiple linear regression and mediation analysis were used to explore the relationship among childhood stress, emotion processing, and acute stress response. Higher level of childhood abuse (but not neglect) was distinctly related to smaller LPP amplitudes to negative stimuli, as well as smaller heart rate reactivity to acute stress. For these participants, smaller LPP amplitudes were linked with smaller heart rate reactivity to acute stress. Furthermore, decreased LPP amplitudes to negative stimuli mediated the relationship between higher level of childhood abuse and blunted heart rate reactivity to stress. Consistent with the dimensional model of childhood stress, our study showed that childhood abuse is distinctly associated with neural as well as physiological response to threat. Furthermore, the blunted neural response to negative stimuli might be the underlying mechanism in which childhood abuse leads to the blunted acute stress response. Considering that all the participants are healthy in the present study, the blunted processing of negative stimuli might rather reflect adaptation instead of vulnerability, in order to prevent stress overshooting in the face of early-life threatening experiences.</p>","PeriodicalId":51173,"journal":{"name":"Stress-The International Journal on the Biology of Stress","volume":"26 1","pages":"2195503"},"PeriodicalIF":2.3,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9363539","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Identification of salivary microRNA profiles in male mouse model of chronic sleep disorder.","authors":"Yuta Yoshida,&nbsp;Yuhei Yajima,&nbsp;Yuri Fujikura,&nbsp;Haotong Zhuang,&nbsp;Sayaka Higo-Yamamoto,&nbsp;Atsushi Toyoda,&nbsp;Katsutaka Oishi","doi":"10.1080/10253890.2022.2156783","DOIUrl":"https://doi.org/10.1080/10253890.2022.2156783","url":null,"abstract":"<p><p>Chronic sleep disorders (CSD) comprise a potential risk factor for metabolic and cardiovascular diseases, obesity and stroke. Thus, the identification of biomarkers for CSD is an important step in the early prevention of metabolic dysfunctions induced by sleep dysfunction. Diagnostic saliva samples can be easily and noninvasively collected. Thus, we aimed to identify whole microRNA (miRNA) profiles of saliva in control and psychophysiologically stressed CSD mouse models and compare them at Zeitgeber time (ZT) 0 (lights on) and ZT12 (lights off). The findings of two-way ANOVA revealed that the expression of 342 and 109 salivary miRNAs was affected by CSD and the time of day, respectively. Interactions were found in 122 miRNAs among which, we identified 197 (ZT0) and 62 (ZT12) upregulated, and 40 (ZT0) and seven (ZT12) downregulated miRNAs in CSD mice. We showed that miR-30c-5p, which is elevated in the plasma of patients with hypersomnia, was upregulated in the saliva of CSD mice collected at ZT0. The miRNAs, miR-10a-5p, miR-146b-5p, miR-150-5p, and miR-25-3p are upregulated in the serum of humans with poor sleep quality, and these were also upregulated in the saliva of CSD mice collected at ZT0. The miRNAs miR-30c, miR146b-5p, miR150, and miR-25-5p are associated with cardiovascular diseases, and we found that plasma concentrations of brain natriuretic peptides were significantly increased in CSD mice. The present findings showed that salivary miRNA profiles could serve as useful biomarkers for predicting CSD.</p>","PeriodicalId":51173,"journal":{"name":"Stress-The International Journal on the Biology of Stress","volume":"26 1","pages":"21-28"},"PeriodicalIF":2.3,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10797868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Testosterone and cortisol responses to acute and prolonged stress during officer training school.","authors":"Regula Zueger,&nbsp;Hubert Annen,&nbsp;Ulrike Ehlert","doi":"10.1080/10253890.2023.2199886","DOIUrl":"https://doi.org/10.1080/10253890.2023.2199886","url":null,"abstract":"<p><p>Prolonged or severe stress has been found to inhibit the hypothalamic-pituitary-gonadal axis (HPG) and its testosterone release. In contrast, acute stress, including competition, social evaluation, or physical challenges, shows more inconsistent response patterns. This study examined changes in cortisol and testosterone across different types and durations of stress in the same individuals. We further explored the influence of baseline levels on hormonal stress responses. Sixty-seven male officer cadets in the Swiss Armed Forces (mean age 20.46 years ± 1.33) were assessed during two different acute stressors-the Trier Social Stress Test for Groups (TSST-G) and a brief military field exercise-and in the long-term during the 15-week officer training school. Several saliva samples were collected before and after the acute stressors for cortisol and testosterone. Morning testosterone was assessed four times during officer training school. There were significant increases in cortisol and testosterone during the TSST-G and the field exercise. Baseline levels of testosterone were negatively associated with acute cortisol response during the field exercise but not during the TSST-G. Morning saliva testosterone decreased during the first 12 weeks of officer training school and increased again in week 15, with no differences to baseline levels. The findings suggest that group stress tests such as the TSST-G or field exercises in groups may be particularly challenging for young men. The results also point to an adaptive role of testosterone during acute challenges during prolonged stress.</p>","PeriodicalId":51173,"journal":{"name":"Stress-The International Journal on the Biology of Stress","volume":"26 1","pages":"2199886"},"PeriodicalIF":2.3,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9409401","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acute psychosocial stress weakens the sense of agency in healthy adults.","authors":"Yayun Chu,&nbsp;Guanhua Huang,&nbsp;Yunyun Li,&nbsp;Qin Chen,&nbsp;Jiajia Liu,&nbsp;Ke Zhao,&nbsp;Xiaolan Fu","doi":"10.1080/10253890.2023.2195511","DOIUrl":"https://doi.org/10.1080/10253890.2023.2195511","url":null,"abstract":"<p><p>The sense of agency (SoA) refers to the feeling of being in control of one's actions and the subsequent consequence of these actions. Emotional context seems to alter the strength of sense of agency. The present study explored the influence of acute psychosocial stress on the SoA by means of the Trier Social Stress Test (TSST). Self-assessment manikin (SAM) and objective physiological indicators (e.g. heart rate, electrodermal activity, and salivary cortisol levels) were utilized to evaluate the effect of the TSST. We also employed the temporal binding effect as an implicit assessment of the participant's SoA. The results indicated that the stress level of the experimental group after TSST was significantly higher than the control group, whilst the temporal binding scores of the experimental group decreased after TSST manipulation. In short, acute psychosocial stress with intense emotional arousal weakened the sense of agency.</p>","PeriodicalId":51173,"journal":{"name":"Stress-The International Journal on the Biology of Stress","volume":"26 1","pages":"2195511"},"PeriodicalIF":2.3,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9664388","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Gamma-amino butyric acid (GABA) supplementation alleviates dexamethasone treatment-induced oxidative stress and inflammation response in broiler chickens.","authors":"Mokhtar Fathi,&nbsp;Shahryar Saeedyan,&nbsp;Majid Kaoosi","doi":"10.1080/10253890.2023.2185861","DOIUrl":"https://doi.org/10.1080/10253890.2023.2185861","url":null,"abstract":"This experiment was conducted to investigate the effect of Gamma-amino butyric acid (GABA) on growth performance, serum and liver antioxidant status, inflammation response and hematological changes, in male broiler chickens under experimentally induced stress via in-feed dexamethasone (DEX). A total 300 male chicks (Ross 308) on day 7 after hatching, were randomly selected into four groups which were positive control group (PC, without any treatment), negative control (NC, with 1 mg/kg DEX), a third group received 1 mg/kg DEX and 100 mg/kg GABA (DG +) and the last one was (DG ++) which received 1 mg/kg DEX and 200 mg/kg GABA. Each group has five replicates (15 birds/replicate). Dietary GABA modulated DEX-induced adverse effects on body weight, feed intake, and feed conversion ratio. The DEX-induced effect of serum level of IL-6 and IL-10 was reduced by dietary GABA supplementation. The activity of serum and liver superoxide dismutase, catalase, glutathione peroxidase were enhanced and malondialdehyde was reduced by GABA supplementaion. The serum levels of total cholesterol & triglyceride were higher while low density lipoprotein & high density lipoprotein were lower in GABA groups than NC group. GABA supplementation also significantly decreased the heterophil, heterophil/lymphocyte ratio and elevated the activities of aspartate aminotransferase (AST), alanine transaminase (ALT) and alkaline phosphatase (ALP) than NC group. In conclusion, dietary GABA supplementation can alleviate DEX stress-induced oxidative stress and inflammation response.","PeriodicalId":51173,"journal":{"name":"Stress-The International Journal on the Biology of Stress","volume":"26 1","pages":"2185861"},"PeriodicalIF":2.3,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9201821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pre-reproductive stress in adolescent female rats alters maternal care and DNA methylation patterns across generations.","authors":"Hiba Zaidan,&nbsp;Agnieszka Wnuk,&nbsp;Idan M Aderka,&nbsp;Malgorzata Kajta,&nbsp;Inna Gaisler-Salomon","doi":"10.1080/10253890.2023.2201325","DOIUrl":"https://doi.org/10.1080/10253890.2023.2201325","url":null,"abstract":"<p><p>Stress during development affects maternal behavior and offspring phenotypes. Stress in adolescence is particularly consequential on brain development and maturation, and is implicated in several psychiatric disorders. We previously showed that pre-reproductive stress (PRS) in female adolescent rats affects behavior and corticotropin releasing hormone receptor 1 (CRHR1) expression in first- (F1) and second- (F2) generation offspring. We further showed that offspring phenotypes are partially reversed by post-stress treatment with fluoxetine (FLX) or the CRHR1 antagonist NBI27914 (NBI). Epigenetic processes, such as DNA methylation, are implicated in the stress response and interact with maternal care quality across generations. Here, we asked whether PRS and FLX or NBI exposure would affect maternal care and global DNA methylation in the brains of exposed dams and their adult F1 and paternally-derived F2 offspring. We found that PRS decreased self-care while increasing pup-care behaviors. PRS also increased DNA methylation in the amygdala of dams and their F1 male offspring, but decreased it in F2 females. Drug treatment had no effect on maternal care, but affected DNA methylation patterns in F0 and F1 generations. Furthermore, PRS altered the expression of DNA methylating enzymes in brain, blood and oocytes. Finally, maternal care variables differentially predicted methylation levels in PRS and control offspring. Thus, the effects of adolescent stress are long-lasting and impact methylation levels across three generations. Combined with our findings of epigenetic changes in PRS-exposed oocytes, the present data imply that biological changes and social mechanisms act in concert to influence adult offspring phenotypes.</p>","PeriodicalId":51173,"journal":{"name":"Stress-The International Journal on the Biology of Stress","volume":"26 1","pages":"2201325"},"PeriodicalIF":2.3,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9756099","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Effect of Directed Avoidance on Impulsive Behaviors among Individuals with Traits of Borderline Personality Disorder","authors":"Hoi Jin Yoon, Myoung-Ho Hyun","doi":"10.17547/kjsr.2022.30.4.260","DOIUrl":"https://doi.org/10.17547/kjsr.2022.30.4.260","url":null,"abstract":"Background: This study aims to examine the emotion regulation effect of directed avoidance on the impulsive behavior of individuals with traits of borderline personality disorder (BPD). Methods: A total of 44 participants with BPD traits were randomly assigned to the control group (n=22) and treatment group (n=22). Participants in the treatment group were directed to use avoidance when they experienced a negative emotion. Positive and negative emotions and impulsivity were measured before and after the negative emotion was induced; impulsivity was measured using the Stroop test and Contingency Delay task. Results: The Stroop test’s results demonstrated that there was a significant interaction effect of time and error between the groups, specifically, impulsivity increased in the control group when negative emotions were induced. However, the results of Contingency Delay task were marginally significant. The main effect of directed avoidance on discount rate k slightly increased but did not reach a significant level, and the interaction effect between the groups and time was not found. In the control group, discount rate k significantly increased after directed avoidance was induced; however, it was not significant in the treatment group. Conclusions: Findings from our study supported the effect of directed avoidance could be used as an emotional regulation method among individuals with traits of BPD, such as controlling impulsive behaviors. Finally, limitations of this study and implications of the short-term intervention method using the immediate emotional control effect of directed avoidance for the future are discussed.","PeriodicalId":51173,"journal":{"name":"Stress-The International Journal on the Biology of Stress","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47065138","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Relationship between Evaluative Compartmentalization of Self-Structure and Psychological Health","authors":"Jewon Bang, A. Lim","doi":"10.17547/kjsr.2022.30.4.196","DOIUrl":"https://doi.org/10.17547/kjsr.2022.30.4.196","url":null,"abstract":"Background: Evaluative compartmentalization is the tendency to segregate positively and negatively valenced self-beliefs into separate self-aspects. This study examined whether there were differences in reflection and personal growth based on the level of evaluative compartmentalization and differential importance.Methods: A total of 296 undergraduate and graduate students reported self-aspect test, and answered questions about reflection and personal growth via online surveys. The participants were divided based on the level (high or low) of evaluative compartmentalization and differential importance. The effects of evaluative compartmentalization and differential importance on the dependent variables were examined. The data were analyzed using two-way multivariate analysis of covariance (two-way MANCOVA).Results: The main effect of evaluative compartmentalization was significant for reflection and personal growth. The main effect of differential importance was significant for personal growth. The interaction effect of evaluative compartmentalization and differential importance was insignificant for any dependent variable.Conclusions: The findings suggest a need for intervention for integrating self-concept structure and improving differential importance for graduate and undergraduate students.","PeriodicalId":51173,"journal":{"name":"Stress-The International Journal on the Biology of Stress","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46398342","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Research Trends in the Diagnostic Classification of Food Addiction and Future Tasks","authors":"Juwon Lee, Myoung-Ho Hyun","doi":"10.17547/kjsr.2022.30.4.187","DOIUrl":"https://doi.org/10.17547/kjsr.2022.30.4.187","url":null,"abstract":"Background: Although people tend to be exposed to food addiction today, there are no formal diagnostics for Food Addiction. Thus, clinical application for therapy is difficult. The present study reviews the clinical characteristics, mechanisms, and measurement tools, and presents opinions on psychiatric classification to suggest directions for further research.Methods: The authors conducted a literature search using the terms food addiction or FA. The review included 54 Korea and international studies from 1956 to 2021.Results: Food addiction has reported similarities with substance use disorder and binge eating disorder. Consequently, it seems to be more reasonable to categorize it as substance or behavioral addiction rather than an eating disorder. Further research is needed on whether food addiction can be classified as a behavioral addiction in that food does not have intoxication properties by itself. Further, it is worth considering the dimensional classification of binge-eating-related spectrum disorder, given the behavioral similarities.Conclusions: Several studies have attempted to reveal the characteristics of food addiction, but researchers’ views on the psychiatric classification are inconsistent. The addition of food addiction in the Diagnostic and Statistical Manual of Mental Disorder (DSM) seems to require a phased approach. Further work should also verify the effective treatment methods, focusing on underlying mechanism.","PeriodicalId":51173,"journal":{"name":"Stress-The International Journal on the Biology of Stress","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42143144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}