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The comparison of erector spinae plane block and caudal block for postoperative analgesia in paediatric surgery - meta-analysis. 儿科手术术后镇痛中竖脊平面阻滞与尾骨阻滞的比较--荟萃分析。
Medicinski Glasnik Pub Date : 2024-09-01 DOI: 10.17392/1709-21-02
Mahendratama Purnama Adhi, Rapto Hardian, Arif Budiman Susatya, Elizeus Hanindito, Arie Utariani
{"title":"The comparison of erector spinae plane block and caudal block for postoperative analgesia in paediatric surgery - meta-analysis.","authors":"Mahendratama Purnama Adhi, Rapto Hardian, Arif Budiman Susatya, Elizeus Hanindito, Arie Utariani","doi":"10.17392/1709-21-02","DOIUrl":"https://doi.org/10.17392/1709-21-02","url":null,"abstract":"<p><strong>Aim: </strong>To assess the efficacy of Erector Spinae Plane Block (ESPB) compared to caudal block in reducing postoperative pain in paediatric surgery.</p><p><strong>Methods: </strong>An electronic literature search was conducted using the Cochrane Library, PubMed, and Google Scholar databases, with data collected from January 2018 until September 2023. This meta-analysis includes English-language randomized controlled trials (RCTs) studies contrasting ESPB with caudal block in paediatric patients. The primary outcome was the 24-hour post-operative pain scores. The secondary outcome included the time to rescue analgesia, the number of patients requiring rescue analgesia, and the occurrence of post-operative nausea and vomiting (PONV) and urinary retention.</p><p><strong>Results: </strong>Five RCTs with 295 samples were included. The results showed no significant difference between ESPB and caudal block in postoperative pain scores at 1st hour SMD (standardized mean difference) of -0.17 (95% CI -0.70, 0.36; I2=76%; p= 0.53), 2nd hour of SMD: -0.50 (95% CI -1.21, 0.21; I2=88%; p=0.17), 6th hour SMD -1.09 (95% CI -2.21, 0.03; I2=95%; p = 0.06), 12th hour SMD -0.77 (95% CI -1.75, 0.21; I2=93%; p=0.12), and the 24th hour SMD -0.13 (95% CI -0.39, 0.12;, I2=2%; p=0.30) were found. Furthermore, there was no significant difference in the time first to rescue analgesia, the number of patients requiring analgesia rescue, PONV occurrence, and urinary retention.</p><p><strong>Conclusion: </strong>ESPB and caudal block showed equivalent analgesia efficacy and safety in paediatric surgery.</p>","PeriodicalId":51129,"journal":{"name":"Medicinski Glasnik","volume":"21 2","pages":"259-266"},"PeriodicalIF":0.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142632226","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The correlation between nutritional status and diet quality with acute respiratory infections in preschool children aged 5 to 7 years. 5 至 7 岁学龄前儿童营养状况和饮食质量与急性呼吸道感染的相关性。
Medicinski Glasnik Pub Date : 2024-09-01 DOI: 10.17392/1746-21-02
Melika Melunović, Belma Krdžalić-Zečević, Mirela Lisičić-Konaković, Amela Kulašević, Lejla Kurtalić
{"title":"The correlation between nutritional status and diet quality with acute respiratory infections in preschool children aged 5 to 7 years.","authors":"Melika Melunović, Belma Krdžalić-Zečević, Mirela Lisičić-Konaković, Amela Kulašević, Lejla Kurtalić","doi":"10.17392/1746-21-02","DOIUrl":"https://doi.org/10.17392/1746-21-02","url":null,"abstract":"<p><strong>Aim: </strong>To investigate the relationship between nutritional status (NS) and diet quality (DQ) with the frequency of acute respiratory infections (ARIs) in children aged 5 to 7 years.</p><p><strong>Methods: </strong>Data were obtained through questionnaires. Anthropometric measurement, correlations between body mass index (BMI) and DQ with frequency of ARIs were analysed.</p><p><strong>Results: </strong>A total of 129 children with an average age of 72.2±4.2 months were examined. Malnourished children had a 3.4 times higher probability of ARIs (OR=3.449; p=0.025, 95% CI=0.109-29.049) and a 5.6 times higher probability of bronchopneumonia compared to those with normal weight (OR=5.643; p=0.049, 95% CI=0.874-36.434). There was a significant positive association between the consumption of meat and meat products with bronchitis (p=0.030; OR 9.921; 95% CI -1.252, +78.610) and a significant negative relationship between the consumption of cooked meals and ARIs in total (p=0.015; OR 0.046; 95% CI -0.004, +0.552). Unexpectedly, a significant positive association was found between the consumption of fresh fruits and vegetables and some respiratory infections, which needs to be verified with additional analyses.</p><p><strong>Conclusion: </strong>DQ and NS are associated with the frequency of ARIs in preschool children. Additional analyses are needed with a larger number of participants in order to form more precise conclusions.</p>","PeriodicalId":51129,"journal":{"name":"Medicinski Glasnik","volume":"21 2","pages":"328-333"},"PeriodicalIF":0.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142632231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Assessment of the risk of falls among elderly persons in primary care settings. 评估基层医疗机构中老年人跌倒的风险。
Medicinski Glasnik Pub Date : 2024-09-01 DOI: 10.17392/1743-21-02
Suzana Savić, Larisa Gavran, Verica Petrović, Gordana Tešanović, Olivera Batić-Mujanović, Goran Borjanović
{"title":"Assessment of the risk of falls among elderly persons in primary care settings.","authors":"Suzana Savić, Larisa Gavran, Verica Petrović, Gordana Tešanović, Olivera Batić-Mujanović, Goran Borjanović","doi":"10.17392/1743-21-02","DOIUrl":"https://doi.org/10.17392/1743-21-02","url":null,"abstract":"<p><strong>Aim: </strong>To investigate the risk for falls in elderly patients treated in the Primary Health Care Centre Gradiška, Bosnia and Herzegovina.</p><p><strong>Methods: </strong>This study included 500 patients aged 65 and older. They were chosen randomly by 10 family physicians. Data collection took place every Wednesday and Friday, between January 2022 and July 2022. The patients' gait and balance assessment were performed using the Tinetti Gait and Balance Tool to assess the risk of falls. A supplementary questionnaire was created to record data about the patients' age, sex, chronic diseases, and drugs they take.</p><p><strong>Results: </strong>Among the included patients there were 266 females (53.2%) and 234 (46.8%) males, with the mean age of 75.25 years. The Tinetti test showed that the risk of falls was high for patients older than 75 years, 111 patients (69.8%), and 48 patients (30.2%) aged 65 to 74 (p=0.000). The risk of falling was higher for female, 93 (35%), than male patients, 66 (28.2%) (p=0.018). Considering chronic diseases, a high risk of falls was found in 32 (2.1%) patients with heart failure (p=0.029) and 19 (11.9%) patients with osteoporosis (p=0.000). Patients who used antihypertensive drugs had the highest risk for falls, 124 (78.0%) (p=0.757).</p><p><strong>Conclusion: </strong>About two-thirds of the examinees over the age of 75 had a high risk of falls, which indicates that family doctors should be more involved in fall prevention of elderly patients and constantly educate older patients and their families about it.</p>","PeriodicalId":51129,"journal":{"name":"Medicinski Glasnik","volume":"21 2","pages":"398-403"},"PeriodicalIF":0.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142632148","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Essential role of Moringa-albumin (MA) formulation in the maintenance of complement regulatory proteins on erythrocyte (TER-119) cells in diabetic mouse models Moringa-albumin (MA) 配方在糖尿病小鼠模型中维持红细胞 (TER-119) 细胞上补体调节蛋白的重要作用
Medicinski Glasnik Pub Date : 2024-07-23 DOI: 10.17392/1685-21-02
Noviana Dwi Lestari, Sulistyo Mulyo Agustini, Moh Dliyauddin, Wahyu Isnia Adharini, Ruri Vivian Nilamsari, N. Widodo, Sri Rahayu, M. Rifa’i
{"title":"Essential role of Moringa-albumin (MA) formulation in the maintenance of complement regulatory proteins on erythrocyte (TER-119) cells in diabetic mouse models","authors":"Noviana Dwi Lestari, Sulistyo Mulyo Agustini, Moh Dliyauddin, Wahyu Isnia Adharini, Ruri Vivian Nilamsari, N. Widodo, Sri Rahayu, M. Rifa’i","doi":"10.17392/1685-21-02","DOIUrl":"https://doi.org/10.17392/1685-21-02","url":null,"abstract":"\u0000 <p><strong>Aim</strong> To evaluate the essential role of Moringa-albumin (MA) formulation in the maintenance of complement regulatory proteins through CD55 and CD59 on erythrocyte (TER-119).<br /><strong>Methods</strong> Strepto-zotocin (145 mg/kg) was used to induce diabetes mice. In diabetes mellitus (DM) model mice were treated with MA formulation for 14 days at a D1 - 500 mg/kg (M) + 620 mg/kg BW (A), D2 - 1000 mg/kg (M) + 420 mg/kg (A), and D3 - 1500 mg/kg (M) + 200 mg/kg (A). On the 15th day, the mice were dissected for the isolation of their bone marrow by the flushing method. The analysis flow cytometry was performed to find out the TER-119, CD55, and CD59 expressions. The data were statistically analyzed with one-way ANOVA (&rho;&le; 0.05) and Tukey test using SPSS version 16 for Windows.<br /><strong>Results</strong> The effect of MA administration in D3 group have a significant effect on increasing the profile of erythrocytes (TER-119), compared to DM (&rho;&le;0.05) group (STZ Injection-no treatment), as well as CD59 expressed by erythrocytes. MA administration in D1 group and D3 group significantly increased the profile of CD55 expressed by erythrocytes compared to DM (&rho;&le;0.05).&nbsp;<br /><strong>Conclusions</strong> MA formulation with D3 group (1500 mg/kg (M) + 200 mg/kg (A)) was able to maintain or control complement regula-tory proteins (CD55 and CD59) on red blood cells (erythro-cytes/TER-119) in DM.</p>\u0000","PeriodicalId":51129,"journal":{"name":"Medicinski Glasnik","volume":"97 15","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141812485","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ertl surgery on the short fibula stump after war injury 战伤后腓骨短残端 Ertl 手术
Medicinski Glasnik Pub Date : 2024-07-23 DOI: 10.17392/1744-21-02
Viktor Shevchuk, Y. Bezsmertnyi, O.Yu. Bezsmertnyi, Olexander Branitsky
{"title":"Ertl surgery on the short fibula stump after war injury","authors":"Viktor Shevchuk, Y. Bezsmertnyi, O.Yu. Bezsmertnyi, Olexander Branitsky","doi":"10.17392/1744-21-02","DOIUrl":"https://doi.org/10.17392/1744-21-02","url":null,"abstract":"\u0000 <p><strong>Aim</strong> To propose a new technique of Ertl-type surgery for significantly shortened and valgus deviated fibula stump.&nbsp;<br /><strong>Methods</strong> We present the case of a 26-year-old patient who underwent reamputation surgery to replace a significantly shortened fibula stump using a distraction regenerate formed after tibial stump osteotomy and dosed distraction of the autograft using the Ilizarov apparatus. Its advantage is the elimination of valgus deviation of the fibula remnant, its lengthening, formation of bone synostosis, and increase of the bearing surface, which provides the possibility of total contact prosthetics. Ra-diography, ultra-sound and MRI were used to monitor the regeneration. The observation period was 28 months.<br /><strong>Results</strong> Within 98 days after the operation, a regenerate was formed, replenishing the length of the fibula stump, the end of the fibula stump was consolidated with the re-generate, increasing the area of the bearing surface of the tibia stump by 2.5 times, which allowed for temporary and then permanent prosthetics.<br /><strong>Conclusion</strong> The proposed technique can be useful in reconstructive operations on the stump of the tibia.</p>\u0000","PeriodicalId":51129,"journal":{"name":"Medicinski Glasnik","volume":"63 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141813181","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Is there any difference in Lactobacillus abundance between age groups during ovarian stimulation in fresh in vitro fertilization (IVF) cycles? 在新鲜体外受精(IVF)周期的卵巢刺激过程中,不同年龄组的乳酸杆菌丰度是否存在差异?
Medicinski Glasnik Pub Date : 2024-07-23 DOI: 10.17392/1715-21-02
Haris Zukić, Devleta Balić, Džanan Osmanović
{"title":"Is there any difference in Lactobacillus abundance between age groups during ovarian stimulation in fresh in vitro fertilization (IVF) cycles?","authors":"Haris Zukić, Devleta Balić, Džanan Osmanović","doi":"10.17392/1715-21-02","DOIUrl":"https://doi.org/10.17392/1715-21-02","url":null,"abstract":"\u0000 <p><strong>Aim</strong> To investigate an influence of age and body mass index (BMI) as determinants of infertility treatment success in vitro fertilization (IVF) procedures confirmed so far, on the amount of <em>Lactobacillus</em> spp. (LS) and <em>Gardnerella vaginalis</em> (GV) in the endometrium in fresh IVF cycles at the time of embryo transfer.<br /><strong>Methods</strong> This a prospective single-centre study included patients who underwent fresh embryo transfer (ET) in a private IVF Centre. A catheter tip for embryo transfer was used for collecting samples from the endometrial cavity. Real time polymerase chain reaction (RT PCR) was used to determine LS and GV quantity. Patients were divided into two age groups: &lt;35 years and &ge;35 years. Normal BMI group included patients with 18.-24.9 kg/m<sup>2</sup>, and the in-creased BMI group patients with BMI &ge; 25kg/m<sup>2</sup>.<br /><strong>Results</strong> Tips for embryo transfer catheters were positive on LS in 55 (96.4%) patients. The median of quantification cycle of RT-PCR (Cq RT-PCR) for LS was 33, and 31 for the younger and older groups, respectively. Twenty-one (36.8%) patients tested positive for GV. The median of Cq RT-PCR for GV was 33 and 34 for the younger and older groups, respectively. There were 36 patients with normal and 18 with increased BMI. BMI showed no correlation with LS amount in the endometrial cavity.<br /><strong>Conclusion</strong> Aging affects the endome-trial microbiome resulting in an increase of <em>Lactobacillus</em> number, but not the number of GV.</p>\u0000","PeriodicalId":51129,"journal":{"name":"Medicinski Glasnik","volume":"102 22","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141812303","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Diagnostic value of procalcitonin, C-reactive protein and leukocyte count in detecting acute appendicitis in paedi-atric patients - a single center experience 降钙素原、C 反应蛋白和白细胞计数在检测儿童急性阑尾炎中的诊断价值 - 单中心经验
Medicinski Glasnik Pub Date : 2024-07-23 DOI: 10.17392/1712-21-02
Sanimir Suljendić, Almira Ćosićkić, Azra Hadžić-Kečalović, Denis Žigić
{"title":"Diagnostic value of procalcitonin, C-reactive protein and leukocyte count in detecting acute appendicitis in paedi-atric patients - a single center experience","authors":"Sanimir Suljendić, Almira Ćosićkić, Azra Hadžić-Kečalović, Denis Žigić","doi":"10.17392/1712-21-02","DOIUrl":"https://doi.org/10.17392/1712-21-02","url":null,"abstract":"\u0000 <p><strong>Aim</strong> To evaluate diagnostic reliability of accessible laboratory findings in recognition of acute appendicitis (AA).&nbsp;<br /><strong>Methods</strong> A retrospective study included children aged 0-15 years with abdominal pain that lasted less than 5 days with at least two of the signs/symptoms - abdominal pain, tenderness of the lower right quadrant of the abdomen, \"return\" sensitivity of the abdomen to palpation, loss of appetite, nausea, vomiting, body temperature&gt;37.2&deg;C. Values of procalcitonin (PCT), C-reactive protein (CRP) and the leukocyte count were analyzed in the peripheral blood. &nbsp;<br /><strong>Results</strong> Among 114 children, 63 (58.2%) were boys and 50 (41.8%) girls; median age of 9.5 years. Elevated values of PCT were found in 74 (65.5%), CRP in 94 (83.1%), and leukocytes in 78 (69%) (65%) children. Almost uniform significance in the recognition of AA was found for pathological values of PCT and CRP with sensitivity of 65% and 83% and diagnostic accuracy of 63% and 59%, respectively, but somewhat lower sensitivity for leukocytes, 61%. A very high predictive value of 98% for PCT and CRP, and PCT with leukocytes was found; CRP with leukocytes had a negative predictive value of 100%.&nbsp;<br /><strong>Conclusion</strong> PCT values have significant sensitivity, specificity and diagnostic accuracy in recognizing AA, while CRP and leukocytes, with high sensitivity, as non-specific markers can be a significant support for clinical assessment in the timely diagnosis of AA.</p>\u0000","PeriodicalId":51129,"journal":{"name":"Medicinski Glasnik","volume":"49 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141810592","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association of X-ray disease stage with basic patient data, laboratory values and treatment modalities in patients with seropositive rheumatoid arthritis 血清反应阳性类风湿性关节炎患者的 X 射线疾病分期与患者基本数据、实验室值和治疗方式的关系
Medicinski Glasnik Pub Date : 2024-07-23 DOI: 10.17392/1728-21-02
Alen Omanović, Nejra Mlačo-Vražalić, A. Mlačo
{"title":"Association of X-ray disease stage with basic patient data, laboratory values and treatment modalities in patients with seropositive rheumatoid arthritis","authors":"Alen Omanović, Nejra Mlačo-Vražalić, A. Mlačo","doi":"10.17392/1728-21-02","DOIUrl":"https://doi.org/10.17392/1728-21-02","url":null,"abstract":"\u0000 <p><strong>Aim</strong> To investigate whether the radiographic progression of rheumatoid arthritis (RA) correlates with inflammatory markers and other laboratory values, and its association with treatment modalities.<br /><strong>Methods</strong> This observational study included 125 patients with seropositive RA. Data were obtained from patients&rsquo; medical records from the year of 2022. Inclusion criteria were patients with seropositive RA who had attended follow-up with a rheumatologist. Basic patient data were collected: gender, age, duration of RA, hospital admission, systolic and diastolic blood pressure, and X-ray stage of RA. Stages of RA are defined by the American College of Rheumatology and they ranged from stage 1, which represents no de-structive changes on X-ray, up to stage 4 where bony or fibrous ankylosis is present.<br /><strong>Results</strong> There were no differences in X-ray stages of RA between genders. Patients with a higher X-ray stage were younger and had a longer duration of illness. Patients in stages III and IV had higher systolic blood pressure (BP), patients in stage IV had higher diastolic BP. Erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) were higher in X-ray stages II-IV compared to stage I. The patients treated with methotrexate had higher radio-graphic stages.&nbsp;<br /><strong>Conclusion</strong> X-ray changes can be associated with CRP and ESR levels, since structural damage is related to RA disease activity and functional disability. The use of newer treatment modalities may be required to stop the radiographic progression of RA.</p>\u0000","PeriodicalId":51129,"journal":{"name":"Medicinski Glasnik","volume":"34 9","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141813363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Predictors for major adverse cardiovascular events among patients with acute coronary syndrome in Bosnia and Herzegovina 波斯尼亚和黑塞哥维那急性冠状动脉综合征患者发生主要不良心血管事件的预测因素
Medicinski Glasnik Pub Date : 2024-07-23 DOI: 10.17392/1763-21-02
Namik Selimović, Amina Marić, Armin Šljivo, Aladin Altic, Irma Fajić, Lana Lekić, A. Durak-Nalbantić
{"title":"Predictors for major adverse cardiovascular events among patients with acute coronary syndrome in Bosnia and Herzegovina","authors":"Namik Selimović, Amina Marić, Armin Šljivo, Aladin Altic, Irma Fajić, Lana Lekić, A. Durak-Nalbantić","doi":"10.17392/1763-21-02","DOIUrl":"https://doi.org/10.17392/1763-21-02","url":null,"abstract":"\u0000 <p><strong>Aim</strong> Despite advancements in the diagnosis, treatment and monitoring of patients with acute coronary syndrome (ACS), morbidity and mortality following ACS remain high. The aim of this study was to actively seek possible predictors of adverse outcomes after ACS aiming to identify high-risk patients promptly.<br /><strong>Methods</strong> This retrospective cohort study investigated patients with ACS hospitalized at Clinical Centre of the University of Sarajevo from 2019 to 2021. Patients were followed up for a period of 12 months post-discharge to assess major cardiovascular events (MACE) and MACE associated independent predictors.&nbsp;<br /><strong>Results</strong>. The study included 121 patients, mostly male 102 (84.3%), with a mean age of 60.83&plusmn;12.61 years; prevalent risk factors were hypertension 94 (77.7%), dyslipidaemia 84 (69.4%), diabetes mellitus 91 (75.2%), active smoking 67 (55.4%) and positive family history of cardiovascular diseases 81 (66.9%). MACE occurred in 33 (27.3%) patients since the initial ACS, and those patients were older (p=0.012), had higher level of creatinine (p&lt;0.001), lower ejection fraction at discharge (p&lt;0.001) and larger left atrial diameter (p=0.032). Serum creatinine (OR=1.014, 95% CI 1,003-1,026, p=0.017) and ejection fraction (OR=0.924, 95% CI 0,869-0,984, p=0.013) were independent predictors associated with a 12-month follow up MACE following ACS.<br />Conclusion A monitoring of serum creatinine level, left atrial diameter, and ejection fraction post-acute coronary syndrome as potential indicators of future MACE within a 12-month follow-up period is of great importance. These findings emphasize the need for tailored management strategies to mitigate risks in this patient population.</p>\u0000","PeriodicalId":51129,"journal":{"name":"Medicinski Glasnik","volume":"34 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141813367","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prevalence of respiratory distress syndrome in premature twins compared to premature singletons 早产双胞胎与早产单胎的呼吸窘迫综合征患病率比较
Medicinski Glasnik Pub Date : 2024-07-23 DOI: 10.17392/1638-21-02
Emina Hadžimuratović, Amina Selimović, Admir Hadžimuratović, V. Mišanović, Velma Rebić, Lejla Kurtalić
{"title":"Prevalence of respiratory distress syndrome in premature twins compared to premature singletons","authors":"Emina Hadžimuratović, Amina Selimović, Admir Hadžimuratović, V. Mišanović, Velma Rebić, Lejla Kurtalić","doi":"10.17392/1638-21-02","DOIUrl":"https://doi.org/10.17392/1638-21-02","url":null,"abstract":"\u0000 <p><strong>Aim</strong> To estimate prevalence of respiratory distress syndrome in preterm twins compared to preterm singletons.&nbsp;<br /><strong>Methods</strong> This is a retrospective observational point prevalence study conducted at the level of three neonatal intensive care units. Medical records of all preterm newborns (&lt;37 weeks of gestation) with respiratory distress syndrome treated in a two-year period were reviewed. The birth order of twins, gestational age and mortality were analyzed.<br /><strong>Results</strong> Out of 809 preterm newborns, 104 (12.9%) were twins. Median gestational age at birth was 30.3 (IQR 31.4&ndash;34.2) weeks. Respiratory distress syndrome was diagnosed in 525 (64.9 %) preterm newborns, of which 441 singletons and 84 twins. Prevalence of respiratory distress syndrome in first-born twins was not significantly higher compared with singletons, 67.3% (35/52) vs. 62.6 % (441/705), respectively (p=0.06). Prevalence of respiratory distress syndrome in second-born twins was 94.2 % (49/52), which was significantly higher compared with both singletons and first-born twins (p&lt;0.001). The mortality rate of preterm newborns was significantly higher in second-born twins compared with singletons and first-born twins, 15.4 % vs. 6.8 % &nbsp;(p&lt;0.001) and 15.4 % vs. 5.5% (p&lt;0.001), respectively.&nbsp;<br /><strong>Conclusion</strong> There was a higher risk of respiratory distress syndrome and higher mortality rate in twins compared with singletons, but only in second-born twins the difference was statistically significant.</p>\u0000","PeriodicalId":51129,"journal":{"name":"Medicinski Glasnik","volume":"57 11","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141810575","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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