Maturitas最新文献

{"title":"Associations of menopausal symptoms with job-related stress and social support in Japanese school teachers","authors":"Yukie Matsuura,&nbsp;Toshiyuki Yasui","doi":"10.1016/j.maturitas.2024.108152","DOIUrl":"10.1016/j.maturitas.2024.108152","url":null,"abstract":"<div><h3>Objectives</h3><div>Being a school teacher is highly stressful. This study aimed to clarify the prevalence of menopausal symptoms and explore the association between these symptoms and job-related stress among Japanese school teachers.</div></div><div><h3>Study design</h3><div>A cross-sectional study was conducted among randomly selected elementary and junior high school teachers in Japan. Data from 284 teachers aged 45–60 years were analyzed.</div></div><div><h3>Main outcome measures</h3><div>Menopausal symptoms were measured using the Greene Climacteric Scale, and the Brief Job Stress Questionnaire was used to assess job stressors, social support, and job/family satisfaction. Associations between scores on the Greene Climacteric Scale and on the Brief Job Stress Questionnaire, and demographic information were analyzed.</div></div><div><h3>Results</h3><div>The most common menopausal symptom was “feeling tired or lacking in energy” (reported by 94.4 % of respondents). The total intensity of menopausal, psychological, and somatic symptoms was significantly correlated with the total level of job stress. Moderate correlations were found between depressive symptoms and job stress regarding suitable jobs, job control, and rewarding jobs, while weak correlations were evident between depressive symptoms and job stress regarding quantitative job overload, interpersonal conflict, and poor physical environment. Higher levels of perceived support from supervisors or co-workers and job satisfaction were associated with less severe psychological and somatic symptoms.</div></div><div><h3>Conclusions</h3><div>Most middle-aged school teachers felt tired or lacking in energy. Higher job-related stress and lower levels of support from supervisors or co-workers were correlated with more severe menopausal symptoms. A supportive work environment and stress management are essential for such teachers.</div></div>","PeriodicalId":51120,"journal":{"name":"Maturitas","volume":"191 ","pages":"Article 108152"},"PeriodicalIF":3.9,"publicationDate":"2024-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142645344","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corrigendum to “The ability of decline in intrinsic capacity to indicate the risk of mortality in older adults: A meta-analysis” [Maturitas 189 (2024) 108109]","authors":"Yidan Li ,&nbsp;Tingting Yang ,&nbsp;Xuedan Wang ,&nbsp;Xiang He ,&nbsp;Jianhui Dong ,&nbsp;Qiuxia Qian ,&nbsp;Xingxia Zhang ,&nbsp;Jie Zheng ,&nbsp;Xiangping Fan ,&nbsp;Yuxia Ma","doi":"10.1016/j.maturitas.2024.108144","DOIUrl":"10.1016/j.maturitas.2024.108144","url":null,"abstract":"","PeriodicalId":51120,"journal":{"name":"Maturitas","volume":"191 ","pages":"Article 108144"},"PeriodicalIF":3.9,"publicationDate":"2024-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142586600","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The cross-sectional and longitudinal associations between fruit intake and cognitive performance: the Chinese Healthy Dance Study","authors":"Yuanyuan Li ,&nbsp;Shuai Chen ,&nbsp;Fengping Li ,&nbsp;Benchao Li ,&nbsp;Tingting Li ,&nbsp;Senli Deng ,&nbsp;Xiaoge Wang ,&nbsp;Shuang Rong","doi":"10.1016/j.maturitas.2024.108146","DOIUrl":"10.1016/j.maturitas.2024.108146","url":null,"abstract":"<div><h3>Objective</h3><div>To analyse the association between fruit consumption and cognitive performance in middle-aged and older adults in China.</div></div><div><h3>Methods</h3><div>Participants were drawn from the Chinese Square Dance Cohort. The cross-sectional dataset included 4316 individuals, with their first visit from August 2020 to August 2023. The longitudinal dataset included 1465 participants, with their first visit from August 2020 to December 2021 and follow-up visits from August 2022 to December 2023. Fruit consumption was assessed using a food frequency questionnaire. Standardised neuropsychological assessments were used to measure composite z-scores of cognitive performance, and prevalent and incident mild cognitive impairment.</div></div><div><h3>Results</h3><div>In the cross-sectional analysis, higher quartiles of citrus fruit, drupe, berry, and tropical fruit consumption were associated with higher composite z-scores for cognitive performance and lower odds of prevalent mild cognitive impairment. In the longitudinal analysis, there was a positive association between higher quartiles of citrus fruit intake and the annual rate of change in the composite z-scores for cognitive performance; standardised regression coefficient (95 % confidence interval) for the highest compared with the lowest quartile was 0.05 (0.02–0.08). Moreover, an association between higher quartiles of citrus fruit intake and a lower risk of incident mild cognitive impairment was detected; in the comparison of the highest with the lowest quartile, the risk ratio (95 % confidence interval) was 0.56 (0.36–0.88).</div></div><div><h3>Conclusions</h3><div>The relationship between fruit consumption and cognition varies across the different categories of fruit. Cognitive benefits of citrus fruit consumption were found for middle-aged and older adults. Ascertaining this association might enhance comprehensive dietary recommendations for fruit consumption.</div></div>","PeriodicalId":51120,"journal":{"name":"Maturitas","volume":"191 ","pages":"Article 108146"},"PeriodicalIF":3.9,"publicationDate":"2024-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142632998","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pain during menopause","authors":"Natalie H. Strand ,&nbsp;Ryan S. D'Souza ,&nbsp;Diego A. Gomez ,&nbsp;Madeline A. Whitney ,&nbsp;Sumedha Attanti ,&nbsp;Meredith A. Anderson ,&nbsp;Susan M. Moeschler ,&nbsp;Andrea L. Chadwick ,&nbsp;Jillian A. Maloney","doi":"10.1016/j.maturitas.2024.108135","DOIUrl":"10.1016/j.maturitas.2024.108135","url":null,"abstract":"<div><div>Menopause is a biological process marking the end of a woman's reproductive years, typically occurring between the ages of 45 and 55. While often associated with hot flashes, mood swings, and hormonal changes, pain is a frequently overlooked and under-addressed aspect of the menopausal experience. This review article explores the multifaceted nature of pain during menopause, and sheds light on its various manifestations and the factors contributing to its prevalence and severity. Pain during menopause may include musculoskeletal discomfort, headaches or migraines, and vulvovaginal pain. The etiology of these is intricate, involving hormonal fluctuations, psychosocial factors, and genetic predispositions. Fluctuations in estrogen and progesterone levels play a pivotal role in musculoskeletal pain and joint stiffness, and increase susceptibility to conditions such as osteoarthritis. Furthermore, mood disorders, stress, and sleep disturbances may exacerbate the perception of pain. Gender norms, as well as changes in reproductive capacity and societal views on aging, may adversely the impact the self-esteem of individuals undergoing menopause. These symptoms can significantly impact a woman's quality of life, underscoring the need for early identification and appropriate management strategies. This review article highlights the factors contributing to pain during menopause, evaluates the effects of hormones on menopausal pain, and investigates management strategies for pain during menopause, including both pharmacological and non-pharmacological approaches. It also emphasizes the need for further research to better understand the interplay of factors contributing to pain during menopause, in order to allow for more tailored and effective interventions. In understanding and addressing this often-neglected aspect of menopause, healthcare providers can enhance the overall wellbeing and quality of life for women transitioning through this natural life stage.</div></div>","PeriodicalId":51120,"journal":{"name":"Maturitas","volume":"191 ","pages":"Article 108135"},"PeriodicalIF":3.9,"publicationDate":"2024-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142584521","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Menopausal symptoms in breast cancer survivors on adjuvant endocrine therapy compared with those of menopausal women","authors":"Giorgia Asinaro ,&nbsp;Claudia Massarotti ,&nbsp;Anjeza Xholli ,&nbsp;Ambrogio P. Londero ,&nbsp;Matteo Lambertini ,&nbsp;Paola Anserini ,&nbsp;Lucia Del Mastro ,&nbsp;Angelo Cagnacci","doi":"10.1016/j.maturitas.2024.108143","DOIUrl":"10.1016/j.maturitas.2024.108143","url":null,"abstract":"<div><h3>Objectives</h3><div>To compare menopausal symptoms of breast cancer survivors on adjuvant endocrine therapy with those of menopausal women.</div></div><div><h3>Study design</h3><div>In a retrospective nested case-control study menopausal symptoms were compared of breast cancer survivors in pre-, peri- or post-menopause at the time of diagnosis, on tamoxifen or an aromatase inhibitor, plus a gonadotrophin-releasing hormone analogue, if pre- or peri-menopausal, and age-matched control women either in the late peri-menopause, or in surgical or in physiological post-menopause on no hormone replacement therapy. Differences between women on tamoxifen and those on aromatase inhibitors were also evaluated. Weighted and non-weighted <em>t</em>-tests, chi-square tests, and linear or logistic regressions were applied as appropriate.</div></div><div><h3>Main outcome measures</h3><div>Score on the Greene's Climacteric Scale and so of its subscales evaluating vasomotor, anxiety, depression, somatisation and sexuality symptoms.</div></div><div><h3>Results</h3><div>A total of 99 breast cancer survivors (45 on tamoxifen, 54 on aromatase inhibitors) and 554 controls (173 in late perimenopause, 353 in natural and 28 in surgical menopause) were enrolled. The score on the Greene's Climacteric Scale was similar in cases and controls (means ± standard deviation) (21.3 ± 10.4 vs. 22.8 ± 11.5, <em>p</em> = 0.199), as were the subscale scores for vasomotor symptoms, anxiety, and somatisation. The depression score was lower (4.63 ± 3.3 vs. 5.98 ± 3.8; <em>p</em> = 0.001) in breast cancer survivors on adjuvant endocrine therapy, mainly due to a lower score of −2.132 (95 % confidence interval − 3.858/−0.407; <em>p</em> = 0.016) for users of aromatase inhibitors. The sexuality score was higher (1.76 ± 1.1 vs. 1.50 ± 1.1, <em>p</em> = 0.011) than in controls. Differences remained significant when corrected for age, menarche, body mass index, menopausal status (peri- or post-), type of menopause (natural, surgical), use of gonadotrophin-releasing hormone analogues, years of amenorrhea, smoking, alcohol use, and for breast radiotherapy, chemotherapy, tamoxifen or aromatase inhibitors. Among breast cancer survivors, women on aromatase inhibitors had lower scores for anxiety (5.75 ± 2.5vs.5.75 ± 2.5; <em>p</em> = 0.045) and depression (3.89 ± 2.5 vs. 5.13 ± 3.6; <em>p</em> = 0.046) than women on tamoxifen.</div></div><div><h3>Conclusions</h3><div>In breast cancer survivors, adjuvant therapy induces symptoms similar in type and intensity to those of symptomatic menopausal women. Compared with menopausal women, breast cancer survivors, particularly those on aromatase inhibitors, appear to experience less severe depressive symptoms.</div></div>","PeriodicalId":51120,"journal":{"name":"Maturitas","volume":"191 ","pages":"Article 108143"},"PeriodicalIF":3.9,"publicationDate":"2024-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142584430","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fall risk screening in older adults using the “CARE” frailty scale: The NuAge cohort results","authors":"Olivier Beauchet ,&nbsp;Jacqueline Matskiv ,&nbsp;Pierrette Gaudreau ,&nbsp;Gilles Allali ,&nbsp;Anne-Julie Vaillant-Ciszewicz ,&nbsp;Olivier Guerin ,&nbsp;Auriane Gros","doi":"10.1016/j.maturitas.2024.108134","DOIUrl":"10.1016/j.maturitas.2024.108134","url":null,"abstract":"<div><h3>Background</h3><div>“CARE” is an electronic health (e-health) application (app) which assesses frailty with its frailty module and risk of falls with its mobility module. This study examines and compares the risk of incident falls (<em>i.e.,</em> ≥1, ≥2 and severe falls) among older people in Quebec classified as “frail” and those classified as being at a high risk of falls by the CARE app.</div></div><div><h3>Methods</h3><div>A subset of men and women (<em>n</em> = 1151; 74.2 ± 4.2 years; 52.8 % female) who participated in the Quebec Longitudinal Study on Nutrition and Successful Aging (NuAge) were selected for this study. Pre-frail and frail states using the CARE frailty scale as well as high risk of falls estimated by CARE mobility module were determined at baseline. Pre-frail and frail states were merged in a single “frail state” group. Incident falls (<em>i.e.,</em> ≥1, ≥2 and severe falls) were annually recorded over a 3-year follow-up.</div></div><div><h3>Results</h3><div>Both CARE frail state (Odd ratio (OR) ≥1.89 with <em>P</em> ≥ 0.040) and high risk of falls estimated by the CARE mobility module (OR) ≥3.32 with <em>P</em> ≥ 0.023) were significantly associated with incident falls (<em>i.e.,</em> at least one fall) and recurrent falls (<em>i.e.,</em> at least two falls). A greater association with these fall outcomes was observed with the high risk of falls than with the frail state. No significant association between the high risk of falls and severe falls was found (OR = 1.71 with <em>P</em> = 0.227), whereas that was the case with frail state (OR = 3.08 with <em>P</em> = 0.003).</div></div><div><h3>Conclusions</h3><div>Frail state determined by the CARE frailty module and high risk of falls determined by the CARE mobility module were both significantly associated with fall outcomes, a greater association being shown with the CARE high risk of falls and with CARE frail state for severe falls. These results suggest that the CARE app may be useful for screening older people for the risk of falls.</div></div>","PeriodicalId":51120,"journal":{"name":"Maturitas","volume":"191 ","pages":"Article 108134"},"PeriodicalIF":3.9,"publicationDate":"2024-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142584512","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Women's expectations for system support for a healthy menopausal transition: A pilot study","authors":"Marzena Nieroda ,&nbsp;Dania Posso ,&nbsp;Abdul Seckam","doi":"10.1016/j.maturitas.2024.108133","DOIUrl":"10.1016/j.maturitas.2024.108133","url":null,"abstract":"<div><h3>Background</h3><div>This pilot study contributes to the knowledge on healthy menopause by adopting a person-centric, lifelong approach to support a healthy menopausal transition. It focuses on women's expectations of system support for this transition.</div></div><div><h3>Method</h3><div>Twenty-two online in-depth interviews were conducted with women of various ages, experiences, and backgrounds in the United Kingdom, ensuring representation across the menopausal transition journey – before, during and after menopause. The interviews explored perceptions and expectations of healthy menopause and the required support. User journey and systems frameworks guided data collection and analysis. The pilot aimed to verify the feasibility of the developed study approach and protocol.</div></div><div><h3>Results</h3><div>A healthy menopausal transition is seen as preserving essential capacities to maintain normal daily activities despite bodily changes, a crucial aspect of ageing. Participants outlined a journey of awareness, contemplation of lifestyle adjustments, experimentation with new behaviours, and habit formation. These findings underscore the importance of fostering awareness and support for menopausal transition early in life. Participants also stressed the impact of the broader environment across the ageing journey, including education, research, health services, workplace dynamics, built environment, food industry, technology and innovation, media, advertising, and social networks.</div></div><div><h3>Conclusions</h3><div>This work highlights person-centric perceptions of healthy menopause, complementing existing biology-centred perspectives. By introducing a co-creation approach at the system level, it offers opportunities to define holistic support for the menopausal transition. The findings informed a knowledge exchange and ideation workshop with forty relevant system stakeholders to advance solution co-creation.</div></div>","PeriodicalId":51120,"journal":{"name":"Maturitas","volume":"190 ","pages":"Article 108133"},"PeriodicalIF":3.9,"publicationDate":"2024-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142515516","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Associations between the incidence of Fuchs' endothelial corneal dystrophy and menopausal hormone therapy use and exposure to endogenous estrogen","authors":"Amy E. Millen ,&nbsp;Jing Nie ,&nbsp;Yihua Yue ,&nbsp;Chris A. Andrews ,&nbsp;Jean Wactawski-Wende ,&nbsp;Robert B. Wallace ,&nbsp;Aladdin H. Shadyab ,&nbsp;Sangita P. Patel","doi":"10.1016/j.maturitas.2024.108132","DOIUrl":"10.1016/j.maturitas.2024.108132","url":null,"abstract":"<div><h3>Objectives</h3><div>End-stage Fuchs' endothelial corneal dystrophy is a leading cause of corneal blindness, with a higher prevalence in females than in males. Few modifiable risk factors have been identified. We examined associations between menopausal hormone therapy use (never/past/current), duration of hormone therapy use, estimated lifetime exposure to endogenous estrogen, and serum estradiol with incident Fuchs' endothelial corneal dystrophy in a cohort of postmenopausal women.</div></div><div><h3>Study design</h3><div>This was a prospective analysis in the Women's Health Initiative Observational Study.</div></div><div><h3>Main outcome measures</h3><div>Incident cases of Fuchs' endothelial corneal dystrophy were identified from the Women's Health Initiative Observational Study baseline (1993–1998) through 2019 using Medicare claims data.</div></div><div><h3>Results</h3><div>In 22,980 women, 1382 incident cases of Fuchs' endothelial corneal dystrophy (annualized incidence rate and 95 % confidence interval = 5.0 [4.8–5.3] cases per 1000 person-years) were identified. The adjusted hazard ratios and 95 % confidence intervals for Fuchs' endothelial corneal dystrophy were 1.02 (0.88–1.18) and 0.89 (0.79–0.997) for past and current hormone therapy use (vs. never use) at baseline, respectively. Adjusted hazard ratios (95 % confidence interval) were 0.90 (0.79–1.03) and 0.95 (0.84–1.08), p-trend = 0.36, for ≤10 and &gt; 10 years, respectively, of hormone therapy use compared with no use; and the adjusted hazard ratio (95 % confidence interval) was 1.01 (0.88–1.15), p-trend = 0.87, for 46.7–59.0 versus 13.8–41.0 years of estimated lifetime exposure to endogenous estrogen. No statistically significant associations were observed with serum estradiol concentrations in a subset of participants.</div></div><div><h3>Conclusions</h3><div>In this cohort of postmenopausal women, current hormone therapy use (vs. never use) showed evidence of protection against the development of Fuchs' endothelial corneal dystrophy; however, duration of hormone therapy use, estimated lifetime exposure to endogenous estrogen, or serum estradiol concentrations were not significantly associated with a decreased risk of Fuchs' endothelial corneal dystrophy.</div></div>","PeriodicalId":51120,"journal":{"name":"Maturitas","volume":"191 ","pages":"Article 108132"},"PeriodicalIF":3.9,"publicationDate":"2024-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142635474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Morning tiredness and insomnia symptoms are associated with increased blood pressure in midlife women","authors":"Ville Rimpilä ,&nbsp;Katja Valli ,&nbsp;Tero Vahlberg ,&nbsp;Tarja Saaresranta","doi":"10.1016/j.maturitas.2024.108131","DOIUrl":"10.1016/j.maturitas.2024.108131","url":null,"abstract":"<div><h3>Objectives</h3><div>The objective of this study was to investigate how blood pressure, sleep architecture, sleep-disordered breathing, body habitus, and levels of serum follicle-stimulating hormone are associated with symptoms of insomnia and sleep quality during menopausal transition.</div></div><div><h3>Methods</h3><div>64 healthy premenopausal women (aged 45–47 years) were recruited to the study. Data were collected at baseline and at 10-year follow-up during sleep laboratory and laboratory visits. A sleep questionnaire was used to evaluate sleep quality and insomnia symptoms. Data were analysed using multiple linear and logistic regression with a backward method.</div></div><div><h3>Results</h3><div>During the menopausal transition, a change in insomnia symptoms was associated with a change in morning systolic blood pressure (β = 0.114 (CI95% 0.023–0.205), p = 0.016). At follow-up, at the age of 56, a higher percentage of REM sleep was associated with a lower odds of restless sleep (OR = 0.842 (95 % CI 0.742–0.954), p = 0.007), while both higher systolic and diastolic evening blood pressure was associated with an increased odds of morning tiredness.</div><div>OR = 1.047 (95 % CI 1.003–1.092), p = 0.034 and OR = 1.126 (95 % CI 1.018–1.245), p = 0.007, respectively.</div></div><div><h3>Conclusions</h3><div>In healthy midlife women, a change blood pressure is related to the development of insomnia symptoms during menopausal transition. In postmenopausal women, a high evening blood pressure may be associated with morning tiredness and a reduced amount of REM sleep may be perceived as restless sleep.</div></div>","PeriodicalId":51120,"journal":{"name":"Maturitas","volume":"190 ","pages":"Article 108131"},"PeriodicalIF":3.9,"publicationDate":"2024-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142441450","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The role of menopausal symptoms on future health and longevity: A systematic scoping review of longitudinal evidence","authors":"Robin Andrews ,&nbsp;Arron Lacey ,&nbsp;Kate Bache ,&nbsp;Emma J. Kidd","doi":"10.1016/j.maturitas.2024.108130","DOIUrl":"10.1016/j.maturitas.2024.108130","url":null,"abstract":"<div><div>Women live longer than men but spend more years in poor health. Menopausal symptoms are not generally associated with adverse health outcomes. However, increasingly, evidence suggests they can significantly impact future health and longevity. Understanding the long-term effects of menopausal symptoms will enable clinicians to identify risk factors and intervene with modifications to support healthy aging.</div><div>This review examined the scope of research investigating the association between menopausal symptoms and future health outcomes. We searched for longitudinal cohort studies. Date and geographical restrictions were not applied. Articles were screened and data extracted using standardised methods.</div><div>Included studies examined the role of menopausal symptoms on future health developments using a sample who had experienced menopause and were deemed healthy at baseline, with clear reporting of their menopausal status at symptom assessment.</div><div>We identified 53 eligible studies with data from over 450,000 women enrolled in 28 longitudinal cohorts.</div><div>Cardiovascular disease, psychiatric disorders, diabetes, and reduced bone mineral density were positively associated with menopausal symptoms. Breast cancer was associated with an asymptomatic menopause. Psychological menopausal symptoms and cognitive decline improved after menopause, except among women from low socioeconomic backgrounds.</div><div>These findings demonstrate that menopausal symptoms are important indicators for future health risks. Future work should investigate the impact of underexplored menopausal symptoms on future health, such as sleeping problems and urogenital issues, and evaluate whether treating menopausal symptoms could lead to improvements in future health outcomes. Should future research continue to support these findings, clinical guidelines should be updated to support clinical decision-making in menopause care.</div></div>","PeriodicalId":51120,"journal":{"name":"Maturitas","volume":"190 ","pages":"Article 108130"},"PeriodicalIF":3.9,"publicationDate":"2024-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142376444","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}