Maturitas最新文献

{"title":"Association of nutritional and inflammatory status with all-cause and cardiovascular mortality in adults with sarcopenia: Insights from NHANES","authors":"Yang Yang ,&nbsp;Si Shen ,&nbsp;Xiang Luo ,&nbsp;Yan Liu ,&nbsp;Zhi-Xia Wang ,&nbsp;Yun-Xia Li ,&nbsp;Xin-Yang Zhang ,&nbsp;Zhi-Qiang Zhang","doi":"10.1016/j.maturitas.2025.108233","DOIUrl":"10.1016/j.maturitas.2025.108233","url":null,"abstract":"<div><h3>Objective</h3><div>Associations between scores on the advanced lung cancer inflammation index (ALI) and mortality among sarcopenic adults remains unknown. This study investigates the relationship between ALI and both all-cause and cardiovascular mortality among adults with sarcopenia.</div></div><div><h3>Methods</h3><div>The study involved sarcopenic adults from the National Health and Nutrition Examination Survey (NHANES), conducted between 1999 and 2006 and 2011–2018. Mortality information was acquired from the National Death Index, which tracks deaths through to December 31, 2019. Weighted multivariable Cox proportional hazards regression was employed to calculate hazard ratios (HRs) for mortality in different models. Additionally, the restricted cubic spline (RCS) method was used to investigate non-linear associations. Subgroup analyses and sensitivity analyses were conducted to detect differences and examine the reliability of the findings.</div></div><div><h3>Results</h3><div>This study included 2074 American adults with sarcopenia categorized into quartiles. 701 deaths occurred from all causes, with 236 linked to cardiovascular issues. Multivariate Cox regression models showed that those in the highest ALI quartile had a lower all-cause mortality rate than those in the lowest quartile (model 1: HR = 0.69, 95 % CI 0.55–0.87, <em>P</em> = 0.002; model 2: HR = 0.73, 95 % CI 0.56–0.94, <em>P</em> = 0.017). Likewise, those in the highest ALI quartile had a lower risk of death from cardiovascular causes (model 1: HR = 0.55, 95 % CI 0.36–0.85, <em>P</em> = 0.007; model 2: HR = 0.59, 95 % CI 0.37–0.95, <em>P</em> = 0.031). RCS results revealed an L-shaped correlation between ALI score and all-cause mortality.</div></div><div><h3>Conclusions</h3><div>A higher ALI score was strongly associated with lower rates of both all-cause and cardiovascular mortality among sarcopenic adults, particularly in the older population, males, smokers, and those with hypertension. This suggests that ALI may serve as a risk stratification tool.</div></div>","PeriodicalId":51120,"journal":{"name":"Maturitas","volume":"196 ","pages":"Article 108233"},"PeriodicalIF":3.9,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143548541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"How patient-centered is the gynecological care provided for patients with genitourinary syndrome of menopause in Switzerland? A survey on the implementation of patient-centered care","authors":"Theresa Donhauser ,&nbsp;Ebru Özkan ,&nbsp;Isabell Gulde ,&nbsp;Michaela Gabes ,&nbsp;Margarinta-Meda Munshi ,&nbsp;Christian Apfelbacher ,&nbsp;Petra Stute","doi":"10.1016/j.maturitas.2025.108231","DOIUrl":"10.1016/j.maturitas.2025.108231","url":null,"abstract":"<div><h3>Objectives</h3><div>This study assessed the extent to which patient-centered care has been implemented in patients with genitourinary syndrome of menopause.</div></div><div><h3>Study design</h3><div>An online survey was developed consisting of an introduction and items covering knowledge about patient-centered care and genitourinary syndrome of menopause, inclusion criteria, biographical data, implementation of patient-centered care, competence and barriers in treating patients, treatment options in genitourinary syndrome of menopause and perceived benefit, specific dimensions of patient-centered care and the German version of the Patient-Practitioner Orientation Scale (PPOS-D12). The survey was administered to gynecologists in Switzerland.</div></div><div><h3>Main outcome measures</h3><div>Mean PPOS-D12 scores were correlated with years of professional experience and age. A post-hoc regression analysis was calculated for the PPOS-D12 score with the predicting variables age, years of professional experience, professional setting, and strategies for ensuring patient-centered care.</div></div><div><h3>Results</h3><div>In total, 220 gynecologists with a mean age of 50.64 years (SD = 9.50, range: 33–80 years) took part in the survey. Mean score on the PPOS-D12 was 4.49 (SD = 0.55) and this score was negatively correlated with the age of participants (Spearman's <em>r</em>_s = −0.222, p &lt; .001). Years of professional experience did not correlate with the PPOS-D12 score (Spearman's <em>r</em>_s = −0.018, p = .792). The regression analysis reached significance (<em>F</em>(4, 205) = 3.826, p = .005, R² = 0.069, adjusted R² = 0.051), but only age had a significant association with the PPOS-D12 score (β = 0.035, p &lt; .001).</div></div><div><h3>Conclusions</h3><div>This survey provides an overview of the patient-centeredness of gynecologists in Switzerland, shows possible obstacles (e.g. patient compliance) and proposes solutions (e.g. more resources per patient) for making routine care more patient-centered.</div></div>","PeriodicalId":51120,"journal":{"name":"Maturitas","volume":"196 ","pages":"Article 108231"},"PeriodicalIF":3.9,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143548542","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of hysterectomy without oophorectomy on the health of postmenopausal women: Assessment of physical, psychological, and cognitive factors","authors":"Juan E. Blümel ,&nbsp;Peter Chedraui ,&nbsp;María S. Vallejo ,&nbsp;Carlos Escalante ,&nbsp;Gustavo Gómez-Tabares ,&nbsp;Álvaro Monterrosa-Castro ,&nbsp;Mónica Ñañez ,&nbsp;Eliana Ojeda ,&nbsp;Claudia Rey ,&nbsp;Doris Rodríguez Vidal ,&nbsp;Marcio A. Rodrigues ,&nbsp;Carlos Salinas ,&nbsp;Konstantinos Tserotasl ,&nbsp;Andrés Calle ,&nbsp;Maribel Dextre ,&nbsp;Alejandra Elizalde ,&nbsp;María T. Espinoza","doi":"10.1016/j.maturitas.2025.108229","DOIUrl":"10.1016/j.maturitas.2025.108229","url":null,"abstract":"<div><h3>Objective</h3><div>To determine the impact of hysterectomy without bilateral oophorectomy on the physical, psychological, and cognitive health of postmenopausal women.</div></div><div><h3>Methods</h3><div>This study was a sub-analysis of a cross-sectional, observational study carried out during gynecological consultations in nine Latin American countries. We collected sociodemographic and clinical data and evaluated the women's health using the EQ-5D for health status, the Menopause Rating Scale for menopausal symptoms, the 6-item Female Sexual Function Index for sexual function, the Jenkins Sleep Scale for sleep disturbances, the SARC-F for the risk of sarcopenia, and the Montreal Cognitive Assessment test for cognitive function.</div></div><div><h3>Results</h3><div>The sub-analysis involved 782 postmenopausal women with an average age of 56.9 years and an average body mass index of 26.5 kg/m². The participants had an average of 13.9 years of education, and 45.9 % of them had a university degree. The group of 104 women who had undergone hysterectomy without oophorectomy had a higher body mass index (27.5 ± 4.9 vs 26.3 ± 5.1 kg/m², <em>p</em> &lt; 0.03), displayed more comorbidities (63.5 % vs 41.7 %, <em>p</em> &lt; 0.001), worse self-perceived health (Odds ratio, OR 2.00, 95 % CI: 1.27–3.15), higher rates of severe menopausal symptoms (OR 2.39, 95 % CI: 1.51–3.77) and sleep disturbances (OR 1.75, 95 % CI: 1.10–2.79), and a higher likelihood of sarcopenia (OR 1.74, 95 % CI: 1.03–2.97) than those who had not undergone hysterectomy. No significant differences were observed regarding sexual function or cognitive performance between the two groups. Moreover, in the six assessed health domains, menopausal hormone therapy (ever use) was found to be a protective factor, regardless of whether or not the woman had undergone a hysterectomy.</div></div><div><h3>Conclusion</h3><div>Women who undergo hysterectomy without oophorectomy may experience persistent physical and psychological symptoms that affect their mental health and quality of life. Menopausal hormone therapy is associated with improved health outcomes.</div></div>","PeriodicalId":51120,"journal":{"name":"Maturitas","volume":"196 ","pages":"Article 108229"},"PeriodicalIF":3.9,"publicationDate":"2025-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143529338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy and safety of fezolinetant and elinzanetant for vasomotor symptoms in postmenopausal women: A systematic review and meta-analysis","authors":"Helen Michaela de Oliveira ,&nbsp;Camilo André Viana Diaz ,&nbsp;Lucas Mendes Barbosa ,&nbsp;Victor Hugo Palhares Flávio-Reis ,&nbsp;Fernanda Valeriano Zamora ,&nbsp;Osvaldo Gonçalves Barbosa Júnior","doi":"10.1016/j.maturitas.2025.108220","DOIUrl":"10.1016/j.maturitas.2025.108220","url":null,"abstract":"<div><h3>Objective(s)</h3><div>Menopause, marked by a decline in estrogen, leads to disruptive vasomotor symptoms like hot flashes and night sweats, significantly affecting quality of life. This meta-analysis evaluated the efficacy and safety of fezolinetant and elinzanetant, two neurokinin 3 receptor antagonists, in managing vasomotor symptoms in postmenopausal women.</div></div><div><h3>Methods</h3><div>Data sources were identified by searches in PubMed, Embase, and the Cochrane Central Register of Controlled Trials up to September 2024. The study followed Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines, with the risk of bias assessed using the version 2 of the Cochrane Risk of Bias Tool for Randomized Trials and evidence quality was evaluated using the Grading of Recommendations Assessment, Development and Evaluation approach. Data were pooled using a random-effects model, and statistical analysis was performed using R version 4.4.1.</div></div><div><h3>Results</h3><div>Ten studies involving 4663 patients were included in the analysis. Elinzanetant &gt;100 mg and fezolinetant ≤45 mg were the most effective doses for reducing vasomotor symptom frequency and severity. Fezolinetant (MD = −1.38) and elinzanetant (MD = −2.04) achieved ≥50 % reductions in vasomotor symptom frequency, with a greater effect in the elinzanetant group. Additionally, elinzanetant improved menopause-specific quality of life. However, higher doses of both drugs were associated with increased adverse effects, with elinzanetant demonstrating a more favorable side-effect profile than fezolinetant.</div></div><div><h3>Conclusions</h3><div>Fezolinetant and elinzanetant are effective options for managing vasomotor symptoms. However, further research is needed to compare these treatments directly and evaluate their long-term safety profiles across different patient populations.</div></div>","PeriodicalId":51120,"journal":{"name":"Maturitas","volume":"195 ","pages":"Article 108220"},"PeriodicalIF":3.9,"publicationDate":"2025-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143465496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Menstrual disorders and the risk of asthma: A prospective study of women from their early twenties to their mid-forties","authors":"Chuyao Jin ,&nbsp;Shyamali Dharmage ,&nbsp;Annette Dobson ,&nbsp;Gita D. Mishra","doi":"10.1016/j.maturitas.2025.108218","DOIUrl":"10.1016/j.maturitas.2025.108218","url":null,"abstract":"<div><h3>Aim</h3><div>To examine whether experiencing menstrual disorders during reproductive years is associated with current asthma among women in their 40s.</div></div><div><h3>Methods</h3><div>Data were from 1240 participants (born between 1973 and 1978) in the Australian Longitudinal Study on Women's Health. Information on menstrual disorders was collected in 1996 and every three years from 2000 to 2018. Current asthma was defined as (1) ever having doctor-diagnosed asthma, and (2) experiencing an asthma attack, and/or using asthma medication in the last 12 months. Logistic regression with generalised estimating equations was used to link current asthma to repeated measures of menstrual disorders, adjusting for socio-demographic characteristics, health behaviours, reproductive factors, preterm birth, and asthma before menarche.</div></div><div><h3>Results</h3><div>Among the participants, 14.2 % had current asthma in their 40s. After adjusting for covariates, report of heavy menstrual bleeding (OR: 1.62 [1.10 to 2.39]), severe period pain (OR: 1.67 [1.10, 2.55]), or premenstrual syndrome (OR: 1.66 [1.20 to 2.31]) across reproductive years was associated with higher odds of current asthma. There was an interaction between report of irregular periods and survey time, with irregular periods being increasingly associated with current asthma in later surveys.</div></div><div><h3>Conclusions</h3><div>Women who experienced heavy menstrual bleeding, severe period pain, and premenstrual syndrome at any point from their 20s to 40s had higher odds of current asthma in their 40s. In contrast, irregular periods were associated with current asthma only when reported during their 40s. These results suggest that women's menstrual characteristics in their reproductive years may reflect their lung health in middle age.</div></div>","PeriodicalId":51120,"journal":{"name":"Maturitas","volume":"195 ","pages":"Article 108218"},"PeriodicalIF":3.9,"publicationDate":"2025-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143465382","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Relationship between menopausal status and suicidal behavior among the Korean population","authors":"Jeongmin Son ,&nbsp;Wanhyung Lee","doi":"10.1016/j.maturitas.2025.108221","DOIUrl":"10.1016/j.maturitas.2025.108221","url":null,"abstract":"<div><h3>Objective</h3><div>We investigated whether, in the Korean population, the risk of suicidal behavior is associated with menopausal status and especially age at menopause. For a deeper understanding of suicidal behavior, participants were asked about suicidal ideation and plans, and actual suicide attempts.</div></div><div><h3>Methods</h3><div>This cross-sectional, population-based study involved 27,524 women for analyzing suicidal ideation, 26,893 women for suicidal plans, 28,682 women for suicide attempts, registered in the Korea National Health and Nutrition Examination Survey (2010−2022). Data on menopausal status, including age at menopause, and suicidal behavior were obtained from a self-reported questionnaire. A logistic regression model was applied to examine whether premature ovarian insufficiency, early menopause, and normal menopause significantly impact rates of suicidal behavior, which was further stratified by depression. Weighted prevalence of suicidal behavior according to age at menopause was also analyzed.</div></div><div><h3>Results</h3><div>Compared with premenopausal status, the risk of suicidal ideation was increased in women with premature ovarian insufficiency by an odds ratio (95 % confidence interval) of 1.53 (1.17–2.01), in women with early menopause by 1.57 (1.28–1.92), and in women with clinically normal menopause by 1.17 (1.00–1.37). The risk of suicidal planning was also increased in women in each of these three respective menopausal groups: 1.92 (1.06–3.47), 1.55 (0.96–2.51), and 1.61 (1.13–2.30). The risk of suicide attempt was also increased in women with premature ovarian insufficiency, by an odds ratio of 2.01 (0.91–4.44), and in women with a clinically normal menopause, by 1.97 (1.22–3.18). The weighted prevalence of suicidal ideation decreased with age at menopause, grouped as <span><math><mo>≤</mo></math></span>30 (21.5 %), 31–40 (14.8 %), 41–50 (11.1 %), and <span><math><mo>≥</mo></math></span>50 (9.4 %).</div></div><div><h3>Conclusion</h3><div>The risks of suicidal ideation and planning were higher in women with premature ovarian insufficiency, early menopause, and clinically normal menopause. The risk of suicide attempt was also higher in women with premature ovarian insufficiency and normal menopause, compared with premenopausal women. Younger age at menopause led to a higher risk of suicidal ideation and planning in general. Due to the limitations of this study's cross-sectional design, longitudinal studies must be conducted to establish more strongly this relationship between menopause and suicidal behavior.</div></div>","PeriodicalId":51120,"journal":{"name":"Maturitas","volume":"195 ","pages":"Article 108221"},"PeriodicalIF":3.9,"publicationDate":"2025-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143465383","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effects of β-hydroxy-β-methylbutyrate supplementation in patients with sarcopenia: A systematic review and meta-analysis","authors":"Wen-Tao Gu ,&nbsp;Lu-Wen Zhang ,&nbsp;Fu-Hua Wu ,&nbsp;Shuo Wang","doi":"10.1016/j.maturitas.2025.108219","DOIUrl":"10.1016/j.maturitas.2025.108219","url":null,"abstract":"<div><h3>Objectives</h3><div>To undertake a systematic review and meta-analysis to examine the evidence base for the effects of β-hydroxy-β-methylbutyrate (HMB) supplementation in patients with sarcopenia.</div></div><div><h3>Design</h3><div>Systematic review and meta-analysis.</div></div><div><h3>Methods</h3><div>The literature was searched via the PubMed, MEDLINE, Web of Science, EMBASE, CINAHL, Scopus, WANFANG, CNKI and VIP databases, through 23rd February 2024. The inclusion criteria were: randomized controlled trials (RCTs); patients diagnosed with sarcopenia defined according to well-accepted clinical consensus; HMB as an intervention; outcomes on muscle mass and/or muscle strength and/or physical performance. Data extraction was completed by independent pairs of reviewers. Meta-analyses of continuous outcomes were performed on the extracted data. Standard mean difference (SMD) with 95 % confidence intervals (CIs) between treatment and control group were used to express intervention effect estimates of HMB for each study. Risk of bias was assessed according to Version 2 of the Cochrane tool for assessing risk of bias in randomized trials (ROB 2).</div></div><div><h3>Results</h3><div>Of 196 records retrieved and screened, five RCTs met the eligibility criteria for qualitative and quantitative analysis, yielding 154, 359 and 359 participants for muscle mass, muscle strength, and physical performance, respectively. For the overall risk of bias, no studies were graded as “high risk of bias”, one (20.0 %) as “some concerns”, and four (80.0 %) as “low risk of bias” according to the ROB 2. The overall meta-analysis revealed a beneficial effect on muscle mass and strength, as demonstrated by a higher skeletal muscle mass index (SMD = 0.32; 95 % CI: [0.00,0.64]; Z value =1.98; <em>P</em> = 0.048), along with an elevated handgrip strength (SMD = 0.65; 95 % CI: [0.05, 1.25]; Z value = 2.12; <em>P</em> = 0.034) in the HMB intervention groups compared with the control groups. However, there was no evidence of a benefit on physical performance, assessed by gait speed (SMD = 0.19; 95 % CI: [−0.14, 0.53]; Z value = 1.14; <em>P</em> = 0.255).</div></div><div><h3>Conclusion</h3><div>Overall, although limited and requiring interpretation with utmost caution, current evidence indicates that HMB supplementation is beneficial for improving muscle mass and strength, but there is no evidence of a benefit on physical performance in patients with sarcopenia. In future, more well-designed HMB intervention trials should be conducted that include populations diagnosed with sarcopenia according to well-accepted clinical consensus.</div></div>","PeriodicalId":51120,"journal":{"name":"Maturitas","volume":"195 ","pages":"Article 108219"},"PeriodicalIF":3.9,"publicationDate":"2025-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143480679","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence of menopausal symptoms around the time of the final menstrual period in Japanese women: Data from the Japan Nurses' Health Study","authors":"Tsuyoshi Higuchi ,&nbsp;Yuki Ideno ,&nbsp;Toshiyuki Yasui ,&nbsp;Takumi Kurabayashi ,&nbsp;Kiyoshi Takamatsu ,&nbsp;Kazue Nagai ,&nbsp;Kunihiko Hayashi","doi":"10.1016/j.maturitas.2025.108216","DOIUrl":"10.1016/j.maturitas.2025.108216","url":null,"abstract":"<div><h3>Objective</h3><div>To characterize various menopausal symptoms by examining their prevalence around the time of the final menstrual period (FMP).</div></div><div><h3>Study design</h3><div>The Japan Nurses' Health Study is a prospective cohort study on women's health. All participants, regardless of their age at the initial survey, were mailed a 4-year follow-up questionnaire that included questions on 21 climacteric symptoms. We analyzed 5189 Japanese women who completed the questionnaire 6 years before to 10 years after their FMP.</div></div><div><h3>Main outcome measures</h3><div>The prevalence of severe climacteric symptoms in the years before and after the time of the FMP (YFMP).</div></div><div><h3>Results</h3><div>Four distinct patterns were identified in the distribution of age-adjusted prevalence ratios by YFMP categories during menopausal transition. The prevalence of Group 1A symptoms (hot flashes, sweats, and poor memory or forgetfulness) was highest at the FMP and this continued through to the postmenopausal period. The prevalence of Group 1B symptoms was highest around the FMP but declined in the postmenopausal period. The independent effect of age was negatively significantly associated with most symptoms in Groups 1A and 1B, which suggested that younger women were more likely to have symptoms if they were in the same YFMP. In Group 2, the prevalence of symptoms did not increase. In Group 3, severe symptoms were rare.</div></div><div><h3>Conclusions</h3><div>Climacteric symptoms can be characterized according to their prevalence in the YFMP. The improved understanding of symptoms based on when they appear relative to the FMP could enable more detailed management of menopausal disorders and facilitate the prediction of changes in symptoms in Japanese women.</div></div>","PeriodicalId":51120,"journal":{"name":"Maturitas","volume":"195 ","pages":"Article 108216"},"PeriodicalIF":3.9,"publicationDate":"2025-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143428033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corrigendum to “Prevalence and impact of vasomotor symptoms associated with menopause among women in Brazil: Subgroup analysis from an international cross-sectional survey” [Maturitas 189 (2024) 108114]","authors":"Rogério Bonassi Machado ,&nbsp;Roberto Soler ,&nbsp;Marcos Freire ,&nbsp;Maria Celeste Osorio Wender ,&nbsp;Luciano Melo Pompei","doi":"10.1016/j.maturitas.2025.108212","DOIUrl":"10.1016/j.maturitas.2025.108212","url":null,"abstract":"","PeriodicalId":51120,"journal":{"name":"Maturitas","volume":"195 ","pages":"Article 108212"},"PeriodicalIF":3.9,"publicationDate":"2025-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143402828","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Methods for the assessment of biological age – A systematic review","authors":"Rebecca Zurbuchen ,&nbsp;Anna von Däniken ,&nbsp;Heidrun Janka ,&nbsp;Michael von Wolff ,&nbsp;Petra Stute","doi":"10.1016/j.maturitas.2025.108215","DOIUrl":"10.1016/j.maturitas.2025.108215","url":null,"abstract":"<div><div>Biological age has long been proposed to complement chronological age because it has the potential to provide a more accurate assessment of someone's ageing process and functional status. At present, there are several methods to determine an individual's biological age through the measurement of biomarkers of ageing. This review compares methods for assessing biological age in adults, analyses biomarkers of ageing, and determines the goals for which biological age can be calculated, in order to help determine a gold standard for measuring biological age. Articles were eligible if studies included a test battery and statistical method to calculate biological age. Literature research included the databases Medline, Embase, Cochrane Library, Web of Science and <span><span>ClinicalTrials.gov</span><svg><path></path></svg></span>. In total, 56 studies were included and the risk of bias in each of them was assessed. The most commonly used methods to assess biological age are Klemera and Doubal's method, principal component analysis, multiple linear regression, PhenoAge and Hochschild's method. Klemera and Doubal's method has proved the most reliable. Apart from using different statistical methods, the difference between the biological ageing scores lies in the choice of biomarkers of ageing, especially the inclusion of chronological age as a biomarker of ageing. Most of the included studies aimed to establish a new biological ageing score or compare biological age to different measurements of functionality of the human body. In conclusion, there is still no consensus on a gold standard and more research on this topic is necessary.</div><div>Study protocol PROSPERO ID: CRD42021287548</div></div>","PeriodicalId":51120,"journal":{"name":"Maturitas","volume":"195 ","pages":"Article 108215"},"PeriodicalIF":3.9,"publicationDate":"2025-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143378793","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}