Maturitas最新文献

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Establishing a risk score for prediction of intrapartum cesarean delivery among older women: A retrospective cohort study 为预测高龄产妇产后剖宫产建立风险评分:一项回顾性队列研究。
IF 3.9 2区 医学
Maturitas Pub Date : 2024-07-24 DOI: 10.1016/j.maturitas.2024.108072
Daniel Gabbai, Itamar Gilboa, Yael Reichman, Lee Reicher, Sharon Maslovitz, Anat Lavie, Yariv Yogev, Emmanuel Attali
{"title":"Establishing a risk score for prediction of intrapartum cesarean delivery among older women: A retrospective cohort study","authors":"Daniel Gabbai,&nbsp;Itamar Gilboa,&nbsp;Yael Reichman,&nbsp;Lee Reicher,&nbsp;Sharon Maslovitz,&nbsp;Anat Lavie,&nbsp;Yariv Yogev,&nbsp;Emmanuel Attali","doi":"10.1016/j.maturitas.2024.108072","DOIUrl":"10.1016/j.maturitas.2024.108072","url":null,"abstract":"<div><h3>Objective</h3><p>To determine risk factors and to develop a risk prediction score for intrapartum cesarean delivery (CD) in women over 40 years old.</p></div><div><h3>Study design</h3><p>A retrospective cohort study, in a single university-affiliated tertiary medical center. All women aged 40 years or more who planned a trial of labor between 2012 and 2022. Women who opted for an elective CD and those with non-viable fetuses were excluded. Maternal and neonatal characteristics of women who delivered vaginally were compared to those who underwent an intrapartum CD. Risk factors were examined using univariate and multivariate analysis. A score was developed to predict the need for intrapartum CD. We assessed a receiver operating characteristic curve to evaluate the performance of our model.</p></div><div><h3>Main outcome measure</h3><p>An unplanned intrapartum cesarean section.</p></div><div><h3>Results</h3><p>During the study period, 122,583 women delivered at our center, of whom 6122 (4.9 %) aged 40 years or more attempted a trial of labor. Of them, 428 (7 %) underwent intrapartum CD. Several independent risk factors were identified, including nulliparity, regional anesthesia, induction of labor, use of antibiotics during labor, multiple gestation, previous cesarean delivery, and the presence of gestational diabetes or preeclampsia. A risk score model, employing a cut-off of 7, demonstrated successful prediction of intrapartum CD, with an area under the curve of 0.86.</p></div><div><h3>Conclusion</h3><p>The score model for intrapartum CD can be used by caregivers to offer a more informed consultation to women aged 40 years or more deciding on the mode of delivery.</p></div>","PeriodicalId":51120,"journal":{"name":"Maturitas","volume":null,"pages":null},"PeriodicalIF":3.9,"publicationDate":"2024-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141790678","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Treatment utilization and non-drug interventions for vasomotor symptoms in breast cancer survivors taking endocrine therapy: Real-world findings from the United States and Europe 接受内分泌治疗的乳腺癌幸存者血管运动症状的治疗利用率和非药物干预措施:来自美国和欧洲的真实世界调查结果。
IF 3.9 2区 医学
Maturitas Pub Date : 2024-07-23 DOI: 10.1016/j.maturitas.2024.108071
Sheryl Kingsberg , Victoria Banks , Cecilia Caetano , Cecile Janssenswillen , Carsten Moeller , Nils Schoof , Mia Harvey , Megan Scott , Rossella E. Nappi
{"title":"Treatment utilization and non-drug interventions for vasomotor symptoms in breast cancer survivors taking endocrine therapy: Real-world findings from the United States and Europe","authors":"Sheryl Kingsberg ,&nbsp;Victoria Banks ,&nbsp;Cecilia Caetano ,&nbsp;Cecile Janssenswillen ,&nbsp;Carsten Moeller ,&nbsp;Nils Schoof ,&nbsp;Mia Harvey ,&nbsp;Megan Scott ,&nbsp;Rossella E. Nappi","doi":"10.1016/j.maturitas.2024.108071","DOIUrl":"10.1016/j.maturitas.2024.108071","url":null,"abstract":"<div><h3>Objectives</h3><p>Vasomotor symptoms induced by endocrine therapy are common in breast cancer survivors and a risk factor for therapy discontinuation and lower quality of life. The REALISE study evaluated the real-world treatment landscape in breast cancer survivors with vasomotor symptoms taking endocrine therapy, including pharmaceuticals, lifestyle changes, and over-the-counter products.</p></div><div><h3>Study design</h3><p>Secondary analysis of the Adelphi Vasomotor Disease Specific Programme™, a large cross-sectional point-in-time survey and chart review conducted in the US and five European countries (February–October 2020). Oncologists provided demographic, clinical, and treatment data for adult breast cancer survivors with induced vasomotor symptoms taking endocrine therapy (tamoxifen or aromatase inhibitors); patients voluntarily completed self-report surveys on their symptom severity, concomitant sleep and/or mood symptoms, lifestyle changes, and use of over-the-counter products.</p></div><div><h3>Main outcome measures</h3><p>Patient characteristics; vasomotor symptom severity; use of pharmaceuticals, lifestyle changes, and over-the-counter products (from pre-defined lists); lines of treatment.</p></div><div><h3>Results</h3><p>Overall, 77 oncologists reported data for 618 breast cancer survivors, of whom 183 (29.6 %) completed self-report forms. Physicians classified 420 (68.0 %) women as experiencing moderate-severe vasomotor symptoms, of whom 66.9 % were receiving treatment. In total, 15.2 % of all breast cancer survivors were prescribed systemic hormone therapy. Venlafaxine (24.7 %), citalopram (16.5 %), and paroxetine (13.6 %) were the most commonly prescribed nonhormonal medications. Lifestyle changes (77.8 %) and over-the-counter products (61.6 %) were common, especially in patients with concomitant sleep and/or mood symptoms.</p></div><div><h3>Conclusions</h3><p>Despite contraindications, a relatively large proportion of treatment-seeking breast cancer survivors with vasomotor symptoms were prescribed systemic hormone therapy. This, combined with high patient-reported use of lifestyle changes and over-the-counter products, suggests a need for symptomatic relief and demand for new nonhormonal alternatives with established safety profiles in this population.</p></div>","PeriodicalId":51120,"journal":{"name":"Maturitas","volume":null,"pages":null},"PeriodicalIF":3.9,"publicationDate":"2024-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141768396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Trends in breast density and other risk factors for breast cancer and associations with trends in the incidence of breast cancer in Korean women 韩国妇女乳房密度和其他乳腺癌风险因素的变化趋势以及与乳腺癌发病率变化趋势的关系
IF 3.9 2区 医学
Maturitas Pub Date : 2024-07-20 DOI: 10.1016/j.maturitas.2024.108070
Soyeoun Kim , Thi Xuan Mai Tran , Boyoung Park
{"title":"Trends in breast density and other risk factors for breast cancer and associations with trends in the incidence of breast cancer in Korean women","authors":"Soyeoun Kim ,&nbsp;Thi Xuan Mai Tran ,&nbsp;Boyoung Park","doi":"10.1016/j.maturitas.2024.108070","DOIUrl":"10.1016/j.maturitas.2024.108070","url":null,"abstract":"<div><h3>Introduction</h3><p>This study investigated the trends in breast density in Korean women and their association with the incidence of breast cancer, incorporating the trends in the known risk factors for breast cancer from an ecological perspective.</p></div><div><h3>Methods</h3><p>The prevalence of risk factors for breast cancer from the National Health and Nutrition Survey, breast density from Korea's national breast cancer screening program, and breast cancer incidence from the Korea Central Cancer Registry during 2010–2018 were applied after age-standardization to the population at the middle of the year 2000. The association between the prevalence of risk factors for breast cancer, the prevalence of dense breast, and the incidence rate of breast cancer was estimated using linear regression.</p></div><div><h3>Results</h3><p>The proportion of age-standardized dense breasts steadily increased from 45.8 % in 2010 to 51.5 % in 2018. The increased prevalence of dense breasts in women was positively related to the prevalence of smoking, drinking, lack of exercise, early menarche age (&lt;15 years old), premenopausal status, nulliparity, and no history of breastfeeding, and negatively related to the prevalence of obesity. The increased prevalence of the dense breast was associated with an increase in the incidence of breast cancer, and 96 % of the variation in breast cancer incidence could be explained by the variation in the prevalence of dense breast. The factors associated with dense breast and breast cancer incidence overlapped.</p></div><div><h3>Conclusions</h3><p>Trends in breast cancer risk factors were associated with an increased prevalence of dense breast, which, in turn, was associated with an increased incidence of breast cancer in Korea.</p></div>","PeriodicalId":51120,"journal":{"name":"Maturitas","volume":null,"pages":null},"PeriodicalIF":3.9,"publicationDate":"2024-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141851061","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Body image and eating issues in midlife: A narrative review with clinical question recommendations 中年时期的身体形象和饮食问题:叙述性综述与临床问题建议
IF 3.9 2区 医学
Maturitas Pub Date : 2024-07-20 DOI: 10.1016/j.maturitas.2024.108068
Lesley Williams , Jyoti Gurung , Patress Persons , Lisa Kilpela
{"title":"Body image and eating issues in midlife: A narrative review with clinical question recommendations","authors":"Lesley Williams ,&nbsp;Jyoti Gurung ,&nbsp;Patress Persons ,&nbsp;Lisa Kilpela","doi":"10.1016/j.maturitas.2024.108068","DOIUrl":"10.1016/j.maturitas.2024.108068","url":null,"abstract":"<div><p>Midlife is a period of transition that is influenced by multiple biopsychosocial and cultural factors. Eating and body image issues are common at this life stage. The purposes of this narrative review are to explore: 1) the aspects of midlife that make individuals vulnerable to eating issues and body image concerns and 2) how these factors may be influenced by weight, cultural background, and socioeconomic status. Within this review, we aim to explore nuances of how eating and body image issues present in some historically marginalized groups at midlife. The aim is to provide clinicians who care for midlife individuals with practical tools to initiate conversations regarding body image and eating issues. Ideally this will facilitate early intervention and assessment for individuals who are struggling with new, chronic, or relapse of symptoms of disordered eating.</p></div>","PeriodicalId":51120,"journal":{"name":"Maturitas","volume":null,"pages":null},"PeriodicalIF":3.9,"publicationDate":"2024-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141853325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The association of menopause with cardiometabolic disease risk factors in women living with and without HIV in sub-Saharan Africa: Results from the AWI-Gen 1 study 撒哈拉以南非洲感染和未感染艾滋病毒的妇女绝经与心脏代谢疾病风险因素的关系:AWI-Gen 1 研究的结果
IF 3.9 2区 医学
Maturitas Pub Date : 2024-07-17 DOI: 10.1016/j.maturitas.2024.108069
Raylton P. Chikwati , Nicole G. Jaff , Nasrin Goolam Mahyoodeen , Lisa K. Micklesfield , Michéle Ramsay , F. Xavier Gómez-Olivé , Shukri F. Mohamed , Solomon S.R. Choma , Jaya A. George , Nigel J. Crowther
{"title":"The association of menopause with cardiometabolic disease risk factors in women living with and without HIV in sub-Saharan Africa: Results from the AWI-Gen 1 study","authors":"Raylton P. Chikwati ,&nbsp;Nicole G. Jaff ,&nbsp;Nasrin Goolam Mahyoodeen ,&nbsp;Lisa K. Micklesfield ,&nbsp;Michéle Ramsay ,&nbsp;F. Xavier Gómez-Olivé ,&nbsp;Shukri F. Mohamed ,&nbsp;Solomon S.R. Choma ,&nbsp;Jaya A. George ,&nbsp;Nigel J. Crowther","doi":"10.1016/j.maturitas.2024.108069","DOIUrl":"10.1016/j.maturitas.2024.108069","url":null,"abstract":"<div><h3>Background</h3><p>Menopause and HIV are associated with cardiometabolic disease. In sub-Saharan Africa there is a growing population of midlife women living with HIV and a high prevalence of cardiometabolic disease.</p></div><div><h3>Objectives</h3><p>The aim of this study was to determine whether menopause and HIV were associated with cardiometabolic disease risk factors in a population of midlife sub-Saharan African women.</p></div><div><h3>Study design</h3><p>This was a cross-sectional comparison of cardiometabolic disease risk factors between 944 premenopausal women (733 living without HIV and 211 living with HIV) and 1135 postmenopausal women (932 living without HIV and 203 living with HIV) in sub-Saharan Africa.</p></div><div><h3>Main outcome measures</h3><p>Anthropometric and cardiometabolic variables were compared between pre- and postmenopausal women living without HIV and between pre- and postmenopausal women living with HIV and between women living without HIV and women living with HIV.</p></div><div><h3>Results</h3><p>The prevalence of HIV was 19.9 %. Age at menopause was lower in women living with HIV than in women living without HIV (48.1 ± 5.1 vs 50.9 ± 4.7 years, p &lt; 0.001).</p><p>Women living with HIV and receiving efavirenz-based antiretroviral therapy had a lower body mass index (BMI), hip circumference, blood pressure and carotid intima media thickness but higher triglyceride levels and insulin resistance than women living without HIV. Antiretroviral therapy-naïve women living with HIV had lower HDL-cholesterol than women living without HIV.</p><p>In this study, menopause was associated with higher LDL-C levels, regardless of HIV status.</p></div><div><h3>Conclusion</h3><p>The high prevalence of obesity and related cardiometabolic disease risk factors in these midlife sub-Saharan African women is not related to the menopausal transition. The association of cardiometabolic disease risk factors with HIV and antiretroviral therapy is complex and requires further investigation in longitudinal studies, as does the negative association of age at final menstrual period with HIV.</p></div>","PeriodicalId":51120,"journal":{"name":"Maturitas","volume":null,"pages":null},"PeriodicalIF":3.9,"publicationDate":"2024-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0378512224001646/pdfft?md5=2e74ccb24b118c3b8c71312324d57b52&pid=1-s2.0-S0378512224001646-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141732349","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Running on empty: Exploring stem cell exhaustion in geriatric musculoskeletal disease 空跑一趟探索老年肌肉骨骼疾病中的干细胞衰竭问题
IF 3.9 2区 医学
Maturitas Pub Date : 2024-07-14 DOI: 10.1016/j.maturitas.2024.108066
Amy Lawton , Nicholas Tripodi , Jack Feehan
{"title":"Running on empty: Exploring stem cell exhaustion in geriatric musculoskeletal disease","authors":"Amy Lawton ,&nbsp;Nicholas Tripodi ,&nbsp;Jack Feehan","doi":"10.1016/j.maturitas.2024.108066","DOIUrl":"10.1016/j.maturitas.2024.108066","url":null,"abstract":"<div><p>Ageing populations globally are associated with increased musculoskeletal disease, including osteoporosis and sarcopenia. These conditions place a significant burden of disease on the individual, society and the economy. To address this, we need to understand the underpinning biological changes, including stem cell exhaustion, which plays a key role in the ageing of the musculoskeletal system. This review of the recent evidence provides an overview of the associated biological processes. The review utilised the PubMed/Medline, Science Direct, and Google Scholar databases. Mechanisms of ageing identified involve a reaction to the chronic inflammation and oxidative stress associated with ageing, resulting in progenitor cell senescence and adipogenic differentiation, leading to decreased mass and quality of both bone and muscle tissue. Although the mechanisms underpinning stem cell exhaustion are unclear, it remains a promising avenue through which to identify new strategies for prevention, detection and management.</p></div>","PeriodicalId":51120,"journal":{"name":"Maturitas","volume":null,"pages":null},"PeriodicalIF":3.9,"publicationDate":"2024-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0378512224001610/pdfft?md5=a337c527edb36dd5bb34383f19868f3f&pid=1-s2.0-S0378512224001610-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141708715","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The role of sex hormone binding globulin levels in the association of surgical and natural premature menopause with incident type 2 diabetes 性激素结合球蛋白水平在手术和自然过早绝经与 2 型糖尿病发病之间的关联中的作用。
IF 3.9 2区 医学
Maturitas Pub Date : 2024-07-10 DOI: 10.1016/j.maturitas.2024.108063
Shuang Wu , Qiong Zhong , Qiying Song , Mengying Wang
{"title":"The role of sex hormone binding globulin levels in the association of surgical and natural premature menopause with incident type 2 diabetes","authors":"Shuang Wu ,&nbsp;Qiong Zhong ,&nbsp;Qiying Song ,&nbsp;Mengying Wang","doi":"10.1016/j.maturitas.2024.108063","DOIUrl":"10.1016/j.maturitas.2024.108063","url":null,"abstract":"<div><h3>Objective</h3><p>To examine associations of surgical and natural menopause before the age of 40 years with the risk of type 2 diabetes (T2D) in women.</p></div><div><h3>Methods</h3><p>A total of 273,331 women from the United Kingdom were recruited between 2006 and 2010 in the UK Biobank (UKB) study, and 146,343 women aged 40 to 69 years who were postmenopausal at baseline were included in the analysis. Surgical menopause and natural premature menopause were defined as bilateral oophorectomy before the age of 40 and menopause before the age of 40 without oophorectomy, respectively. Multivariable Cox regression models were used to estimate the hazard ratios (HRs) and 95 % confidence intervals (CIs) for the association between premature menopause and the incidence of T2D.</p></div><div><h3>Results</h3><p>During a median follow-up of 10.4 years, 47 women with surgical premature menopause, 244 women with natural premature menopause, and 4724 women without premature menopause developed T2D. Compared with women without premature menopause, both surgical premature menopause (adjusted HR = 1.46, 95 % CI: 1.09–1.95; <em>P</em> = 0.01) and natural premature menopause (adjusted HR = 1.20, 95 % CI: 1.06–1.37; <em>P</em> &lt; 0.01) were associated with higher risks of incident T2D in the multivariable-adjusted models. Additionally, we observed a significant interaction between levels of sex hormone binding globulin (SHBG) (<em>P</em><sub>interaction</sub> &lt; 0.01) and the effects of premature menopause on incident T2D. The association between premature menopause and T2D risk appeared to be stronger in women with higher SHBG levels. Furthermore, a joint association was detected between premature menopause and the genetic risk score (GRS) of T2D, with a higher score indicating a higher risk of developingT2D. The highest risk of T2D was observed with higher T2D GRS and surgical premature menopause (adjusted HR = 2.61, 95 % CI: 1.65–4.12; <em>P</em> &lt; 0.01).</p></div><div><h3>Conclusions</h3><p>Surgical menopause and natural menopause before the age of 40 years were associated with an increased risk of T2D among postmenopausal women. The findings also suggest potential interactions of premature menopause with SHBG levels, with the association appearing to be stronger in higher SHBG levels, as well as a joint association between menopause status and genetic risk factors on T2D incidence.</p></div>","PeriodicalId":51120,"journal":{"name":"Maturitas","volume":null,"pages":null},"PeriodicalIF":3.9,"publicationDate":"2024-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141592471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Development and psychometric properties of the Balance in Daily Life (BDL) scale in a population of frail older people 日常生活平衡(BDL)量表在体弱老年人群中的开发和心理测量特性。
IF 3.9 2区 医学
Maturitas Pub Date : 2024-07-08 DOI: 10.1016/j.maturitas.2024.108064
Claire De Labachelerie , Emilie Viollet , Sandrine Alonso , Célia Dauvergne , Mylène Blot , Fabrice Nouvel , Willy Fagart , Thierry Chevallier , Anthony Gelis , Arnaud Dupeyron
{"title":"Development and psychometric properties of the Balance in Daily Life (BDL) scale in a population of frail older people","authors":"Claire De Labachelerie ,&nbsp;Emilie Viollet ,&nbsp;Sandrine Alonso ,&nbsp;Célia Dauvergne ,&nbsp;Mylène Blot ,&nbsp;Fabrice Nouvel ,&nbsp;Willy Fagart ,&nbsp;Thierry Chevallier ,&nbsp;Anthony Gelis ,&nbsp;Arnaud Dupeyron","doi":"10.1016/j.maturitas.2024.108064","DOIUrl":"10.1016/j.maturitas.2024.108064","url":null,"abstract":"<div><h3>Background</h3><p>Balance disorders in older people cause falls, which can have serious functional and economic consequences. No existing scale relates fall risk to daily life situations. This study describes the development, psychometric properties and construct validity of the Balance in Daily Life (BDL) scale, comprising seven routine tasks including answering a phone, carrying a heavy bag, and sitting down and getting up from a chair.</p></div><div><h3>Methods</h3><p>Frail patients aged 65 years or more were prospectively recruited from the geriatric rehabilitation department of a French university hospital. Inclusion criteria included autonomous walking over 20 m and modified Short Emergency Geriatric Assessment score 8–11. Patients with motor skills disorders and comprehension or major memory difficulties were excluded. Patients were assessed on Day 3 and Day 30 with the Balance in Daily Life scale, Timed Up and Go, one-leg stance time, sternal nudge and walking-while-talking tests. The scale was assessed for acceptability, quality, unidimensionality, internal consistency, reliability, temporal stability, responsiveness and construct validity.</p></div><div><h3>Results</h3><p>140 patients (83 ± 6 years) were recruited, of whom 139 were assessed at Day 0 and 133 at Day 30. Acceptability was satisfactory (134/139 patients completed the test), quality assessment showed a slight floor effect (6 % of patients with minimal score) and evaluation of item redundancy found no strong correlation (Spearman &lt;0.7). Unidimensionality was verified (Loevinger H coefficient &gt; 0.5 for all items except item 6 = 0.4728). Internal consistency was good (Cronbach alpha = 0.86). Reliability and temporal stability were excellent (ICC = 0.97 and ICC = 0.92). Responsiveness was verified by significant score change <em>p</em> &lt; 0.0001 between Day 0 and Day 30 (decreased by 1 [0; 2] point), in line with other score changes. Construct validity revealed that the Balance in Daily Life scale was convergent with results of the timed up-and-go and one-leg stance time (<em>p</em> &lt; 0.0001 for both) and tended to be higher for participants who had not fallen in the previous 6 months (<em>p</em> = 0.0528). The new questionnaire was divergent to sternal nudge tests (<em>p</em> = 0.0002) and not related to the walking-while-talking test (<em>p</em> = 0.5969).</p></div><div><h3>Conclusion</h3><p>The Balance in Daily Life scale has good psychometric properties for this population. Its simplicity and innovative nature mean that it can be applied in institutions while being easily modifiable to domestic settings.</p><p>Study registration on <span><span>clinicaltrials.gov</span><svg><path></path></svg></span>: NCT0334382.</p></div>","PeriodicalId":51120,"journal":{"name":"Maturitas","volume":null,"pages":null},"PeriodicalIF":3.9,"publicationDate":"2024-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0378512224001592/pdfft?md5=bfa03f7a81d96989b391d1f1659544be&pid=1-s2.0-S0378512224001592-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141728410","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evidence-based strategies to prevent cognitive decline in older people 预防老年人认知能力下降的循证策略。
IF 3.9 2区 医学
Maturitas Pub Date : 2024-06-27 DOI: 10.1016/j.maturitas.2024.108062
Leon Flicker
{"title":"Evidence-based strategies to prevent cognitive decline in older people","authors":"Leon Flicker","doi":"10.1016/j.maturitas.2024.108062","DOIUrl":"10.1016/j.maturitas.2024.108062","url":null,"abstract":"<div><p>A helpful method to understand cognitive decline in older people is to consider this entity as increasing cognitive frailty caused by a number of interacting pathological processes. Over the last 20 years, multiple lifestyle, environmental and constitutional factors have been linked to the development of cognitive decline. For two interventions based on these factors, increasing physical activity and the control of hypertension, there is class 1 evidence for benefit. Other interventions based on these factors do not have the support of high-level evidence for the alteration of cognitive decline, but their other benefits would argue for their implementation. These interventions include increasing education, smoking cessation, avoiding head injuries, decreasing exposure to air pollution and increased social connections. As cognitive decline is experienced almost universally with ageing, and serious cognitive decline is experienced by substantial numbers of low-risk individuals, whole-of-population intervention strategies are the most effective and efficient. For other interventions to help prevent cognitive decline there is not sufficient evidence for their implementation to be recommended. These include alteration of alcohol ingestion, correction of hearing loss, treatment of depression, dietary interventions, menopausal hormone treatment and monoclonal antibodies directed against amyloid-β.</p></div>","PeriodicalId":51120,"journal":{"name":"Maturitas","volume":null,"pages":null},"PeriodicalIF":3.9,"publicationDate":"2024-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0378512224001579/pdfft?md5=447dcc0f05d987d95ceaf21ad01e8b86&pid=1-s2.0-S0378512224001579-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141474077","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cognitive and behavioral weight management strategies during the menopausal transition: Insights from the Menopause and Weight Loss (ME-WEL) project 更年期过渡期的认知和行为体重管理策略:更年期与体重减轻(ME-WEL)项目的启示。
IF 3.9 2区 医学
Maturitas Pub Date : 2024-06-27 DOI: 10.1016/j.maturitas.2024.108060
Mafalda Leitão , Faustino R. Pérez-López , João Marôco , Filipa Pimenta
{"title":"Cognitive and behavioral weight management strategies during the menopausal transition: Insights from the Menopause and Weight Loss (ME-WEL) project","authors":"Mafalda Leitão ,&nbsp;Faustino R. Pérez-López ,&nbsp;João Marôco ,&nbsp;Filipa Pimenta","doi":"10.1016/j.maturitas.2024.108060","DOIUrl":"10.1016/j.maturitas.2024.108060","url":null,"abstract":"<div><h3>Objective</h3><p>Most women experience weight gain during the menopausal transition, often attributed to behavioral factors. Nevertheless, some women successfully maintain a healthy weight during this phase. This study aims to identify the successful cognitive and behavioral weight management strategies employed by postmenopausal women who effectively maintained a healthy weight during the menopausal transition (from premenopause to postmenopause).</p></div><div><h3>Method</h3><p>Semi-structured interviews were conducted with 31 Portuguese postmenopausal women, aged 45–65 years (<em>mean and standard deviation</em> 54.06 <em>±</em> 5.51) who successfully maintained a healthy weight (body mass index: 18.5 kg/m<sup>2</sup>–24.9 kg/m<sup>2</sup>) during the menopausal transition. The interviews were conducted via telephone <em>(n = 29)</em> and Zoom <em>(n = 2),</em> based on the participant's preference, and ranged from 11 to 52 min <em>(22.06</em> ± 9.95). Using <em>MAXQDA</em> software, deductive-dominant content analysis of the interviews was performed. The <em>Interface of R for the Multidimensional Analyses of Texts and Questionnaire</em> software was used for lexical analysis.</p></div><div><h3>Results</h3><p>The qualitative analysis of <em>cognitive and behavioral strategies for successful weight management</em> yielded 17 categories and 37 sub-categories. Effective cognitive and behavioral strategies (e.g., planning content, stimulus control, support: help from others) were identified, mostly aligning with the Oxford Food and Activity Behaviors Taxonomy. Five new categories emerged: dietary choices, intuitive eating, food literacy, psychological self-care, and effortful inhibition.</p></div><div><h3>Conclusion</h3><p>Knowing effective cognitive and behavioral weight management strategies for menopausal women is relevant, especially considering their status as a high-risk group. This knowledge provides a valuable guide for designing weight management interventions, emphasizing the essential role of behavioral change.</p></div>","PeriodicalId":51120,"journal":{"name":"Maturitas","volume":null,"pages":null},"PeriodicalIF":3.9,"publicationDate":"2024-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0378512224001555/pdfft?md5=4ed29ce49cf6d5156b4ac71051ba9008&pid=1-s2.0-S0378512224001555-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141499975","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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