Maternal and Child Nutrition最新文献

{"title":"The Longitudinal Impact of Fetal Malnutrition on the Anthropometric Growth of Young Children in Leyte, the Philippines.","authors":"Mackenzie E Bruzzio, Jennifer Friedman, Christopher Barry, Emily McDonald, Blanca Jarilla, Veronica Tallo, Susannah Colt","doi":"10.1111/mcn.70120","DOIUrl":"https://doi.org/10.1111/mcn.70120","url":null,"abstract":"<p><p>Poor intrauterine growth has long-term implications for child growth and nutritional status. Fetal malnutrition (FM) is a type of poor intrauterine growth defined by the presence of soft tissue wasting at birth and is identified using the Clinical Assessment of Nutritional Status Score (CANSCORE) tool, independent of gestational age. There is limited evidence evaluating FM as a predictor of longitudinal growth and nutritional status in young children. In this longitudinal birth cohort in Leyte, the Philippines, mother-infant dyads were enroled, and infants were followed for 24 months after delivery. Infants were evaluated using CANSCORE within 48 h of birth by a trained midwife, and FM was defined as CANSCORE < 25. Weight and length were measured at birth, 1-, 6-, 12-, 18- and 24-month visits. Weight-for-age (WAZ), length-for-age (LAZ) and weight-for-length (WLZ) z scores were determined using WHO Anthro. Associations between FM and anthropometric z scores were assessed using multivariable linear regression, adjusting for maternal body mass index (BMI), family socioeconomic status (SES) and child's sex. Among N = 246 infants included for analysis, 8 (3%) were classified with FM at birth. Despite limited power, FM was significantly associated with reduced WAZ, LAZ and WLZ at nearly all timepoints in the fully adjusted models. CANSCORE is a user-friendly tool for assessing FM in areas with limited equipment and predicted that newborns with FM were at continued risk for undernutrition and growth stunting until age 24 months. Identification of FM at birth provides opportunities for targeted early nutrition interventions for high-risk infants.</p>","PeriodicalId":51112,"journal":{"name":"Maternal and Child Nutrition","volume":" ","pages":"e70120"},"PeriodicalIF":2.6,"publicationDate":"2025-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145151742","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of Water, Sanitation, Hygiene and Animal Ownership With Relapse to Acute Malnutrition Among Children Aged 6-59 Months in Mali, South Sudan and Somalia: A Multi-Site Prospective Cohort Study.","authors":"Lauren D'Mello-Guyett, Sarah King, Sherifath Mama Chabi, Feysal Absdisalan Mohamud, Nancy Grace Lamaka, John Agong, Malyun Mohamed, Karim Koné, Karin Gallandat, Mesfin Gose, Mohamed Sheikh Omar, Magloire Bunkembo, Indi Trehan, Anastasia Marshak, Khamisa Ayoub, Ahmed Hersi Olad, Bagayogo Aliou, Heather C Stobaugh, Oliver Cumming","doi":"10.1111/mcn.70116","DOIUrl":"https://doi.org/10.1111/mcn.70116","url":null,"abstract":"<p><p>Children successfully treated through community-based management of acute malnutrition (CMAM) frequently relapse to acute malnutrition (AM) following recovery and discharge. This prospective cohort study examined associations between relapse and household water, sanitation and hygiene (WASH) conditions, as well as animal ownership, in Mali, South Sudan and Somalia. Between April 2021 and June 2022, 1115 children were enrolled, with 964 children followed for 6 months, 242 in Mali, 488 in South Sudan and 234 in Somalia. Relapse to AM occurred in 32%, 63% and 21% of children in Mali, South Sudan and Somalia, respectively. In Mali, relapse risk was higher in households using multiple drinking water sources (aRR 1.71, 95% CI: 1.21-2.43, p = 0.003) or lacking soap (aRR 1.71, 95% CI: 1.03-2.82, p = 0.037). In South Sudan, inadequate drinking water sources, open defecation and the presence of animal faeces in the compound were associated with an increased risk of relapse (aRR 1.20, 95% CI: 1.04-1.38, p = 0.010; aRR 1.16, 95% CI: 1.03-1.30, p = 0.016; aRR 1.13, 95% CI: 1.02-1.26, p = 0.019, respectively). Sheep ownership in Mali (aRR 0.57, 95% CI: 0.40-0.81, p = 0.002) and cattle ownership in South Sudan (aRR 0.78, 95% CI: 0.71-0.85, p = < 0.001) were protective. No significant WASH or animal-related factors were associated with relapse in Somalia. As nearly all household drinking water samples were contaminated across settings and time points, no association could be detected between measured water quality and relapse. While many WASH indicators were not associated with relapse, some inadequate WASH conditions were identified as risk factors for relapse, although heterogeneous across contexts. These findings may help to identify at-risk children during treatment and inform strategies to reduce relapse post-recovery.</p>","PeriodicalId":51112,"journal":{"name":"Maternal and Child Nutrition","volume":" ","pages":"e70116"},"PeriodicalIF":2.6,"publicationDate":"2025-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145139249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of Video-Based Health Education on Birth Outcomes and Anaemia Status of Mothers in Dirashe District South Ethiopia: A Cluster Randomized Controlled Trial.","authors":"Wanzahun Godana Boynito, Kidus Temesgen Worsa, Befikadu Tariku Gutema, Yordanos Gizachew Yeshitila, Godana Yaya Tessema, Tsegaye Yohanis, Stefaan De Henauw, Piet Cools, Bruno Levecke, Souheila Abbeddou","doi":"10.1111/mcn.70122","DOIUrl":"https://doi.org/10.1111/mcn.70122","url":null,"abstract":"<p><p>Undernutrition and infections during pregnancy result in low birth weight (LBW) and maternal anaemia. Social behaviour change communication (SBCC) can promote recommended health practices, potentially improving maternal and neonatal outcomes. This cluster-randomized controlled trial assessed the effects of video-based health education on adherence to iron-folic acid (IFA) supplementation, pregnancy outcomes, and anaemia status among pregnant women in rural Dirashe District, South Ethiopia. Pregnant women in their first trimester across 16 villages were cluster-randomized into either the intervention or control arms. The control arm received standard antenatal care counselling, while the intervention arm received biweekly video-based nutrition and health education at home until delivery. The primary outcomes included adherence to IFA supplementation, birth outcomes, including neonatal length and weight, and maternal haemoglobin concentrations (Hb) throughout pregnancy. Among 596 enroled pregnant women, 519 provided data until delivery. The intervention significantly improved adherence to IFA supplementation, with a mean difference (95% Confidence Interval) of 25.98 (15.60, 36.36) in IFA disappearance rate and a mean percent difference of 14.80% (3.42, 63.99) in self-reported adherence. The intervention significantly improved birth weight, with a mean difference of 204.9 g (38.7, 371.2). Maternal Hb near delivery improved statistically with a mean difference of 0.22 g/dL (0.15, 0.42), with lower anaemia (Hb < 11.0 g/dL) prevalence, with a mean percent difference of -0.08% (-0.12, -0.04). However, no significant effect on birth length or LBW was observed. Video-based SBCC improved IFA adherence, birth weight, and reduced anaemia near delivery. It is a promising approach for community health education in resource-limited settings. REGISTRATION: The study was registered as a clinical trial with the US National Institute of Health (www//.ClinicalTrials.gov; NCT04414527).</p>","PeriodicalId":51112,"journal":{"name":"Maternal and Child Nutrition","volume":" ","pages":"e70122"},"PeriodicalIF":2.6,"publicationDate":"2025-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145131768","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nutrition and Nurture in Infancy and Childhood: Bio-Cultural Perspectives","authors":"","doi":"10.1111/mcn.70095","DOIUrl":"10.1111/mcn.70095","url":null,"abstract":"","PeriodicalId":51112,"journal":{"name":"Maternal and Child Nutrition","volume":"21 S2","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145126475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Serum Folate Concentration Corresponding to the Red Blood Cell Folate Threshold for Increased Risk of Neural Tube Defects Among Ethiopian Women of Reproductive Age.","authors":"Biniyam Tesfaye, Meseret Woldeyohannes, Masresha Tessema, Charles Dale Arnold, Christine M McDonald, Kenneth H Brown","doi":"10.1111/mcn.70121","DOIUrl":"https://doi.org/10.1111/mcn.70121","url":null,"abstract":"<p><p>Neural tube defects (NTDs) are severe birth defects linked to insufficient maternal folate status during early pregnancy. Red blood cell (RBC) folate concentration is the recommended biomarker for predicting NTD risk, with a threshold of 748 nmol/L using the US Centers for Disease Control and Prevention (CDC) microbiological assay. However, in large surveys, serum folate concentration is often measured instead of RBC folate. This study aimed to (1) identify the serum folate concentration that corresponds to the RBC folate threshold for NTD risk using data from Ethiopian women of reproductive age (WRA); (2) evaluate the performance of the serum threshold for population-level NTD risk assessment; and (3) compare the serum folate cutoff determined with the Ethiopian data versus the cutoff derived from a Southern Indian population. Biomarker data from 1570 Ethiopian nonpregnant, non-lactating WRA who participated in the 2015 Ethiopian National Micronutrient Survey were analyzed. Serum and RBC folate concentrations were measured using the CDC microbiological assay. Serum folate cutoffs were identified using unadjusted and adjusted regression models and receiver operating characteristics (ROC) analysis. Adjusted models included the following covariates: age, body mass index (BMI), serum vitamin B₁₂ concentration, presence of inflammation, region, and site of residence. Three serum folate cutoffs were identified: 15.3 nmol/L (unadjusted model), 15.2 nmol/L (adjusted model), and 17.9 nmol/L (ROC analysis). Regression-based cutoffs balanced sensitivity (~76%) and specificity (~62%), while the ROC-derived cutoff improved sensitivity (~83%) but reduced specificity (~50%). Ethiopian cutoffs showed fair discriminatory performance (~AUC:0.7) while the Indian cutoff (~AUC:0.6) showed poorer performance. Because of suboptimal NTD risk prediction using serum folate, future surveys should use RBC folate when possible. In situations where it is not possible to measure RBC folate, population-specific serum folate cutoffs should be determined.</p>","PeriodicalId":51112,"journal":{"name":"Maternal and Child Nutrition","volume":" ","pages":"e70121"},"PeriodicalIF":2.6,"publicationDate":"2025-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145114602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Maternal Dietary Inflammatory Index and Biomarkers of Inflammation at Birth.","authors":"Courtney Dow, Rosalie Delvert, Blandine de Lauzon-Guillain, Judith van der Waerden, Laetitia Davidovic, Olfa Khalfallah, Susana Barbosa, Marie-Aline Charles, Cédric Galera, Barbara Heude","doi":"10.1111/mcn.70108","DOIUrl":"https://doi.org/10.1111/mcn.70108","url":null,"abstract":"<p><p>We evaluated the association between the inflammatory potential of the maternal diet during pregnancy and levels of inflammatory biomarkers measured in cord blood and maternal serum at birth. Dietary inflammatory potential was calculated using the energy-adjusted dietary inflammatory index (E-DII) in the French EDEN and ELFE birth cohorts. Biomarkers of inflammation (interleukin [IL]-1β, IL-6, IL-10, tumor necrosis factor α [TNF-α]) were measured from cord blood (EDEN [n = 758]; ELFE [n = 899]) and maternal serum (in ELFE only; [n = 911]) collected at birth. Additionally, leptin was also measured from cord blood in EDEN (n = 1202) and C-reactive protein was measured from cord blood in ELFE (n = 895). Linear regression models, adjusted for confounders, were used to investigate the association between tertiles of the E-DII score and each log-transformed biomarker. There were no significant associations between the E-DII score and maternal or cord blood biomarkers in either cohort. The energy-adjusted dietary inflammatory index score during pregnancy was not associated with concentrations of inflammatory biomarkers in either maternal serum or cord blood at birth.</p>","PeriodicalId":51112,"journal":{"name":"Maternal and Child Nutrition","volume":" ","pages":"e70108"},"PeriodicalIF":2.6,"publicationDate":"2025-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145103067","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"ABA-Feed Infant Feeding Training for Peer Supporters and Coordinators: Development and Mixed-Methods Evaluation.","authors":"Joanne Clarke, Gill Thomson, Nicola Crossland, Stephan Dombrowski, Pat Hoddinott, Jenny Ingram, Debbie Johnson, Christine MacArthur, Jennifer McKell, Ngawai Moss, Julia Sanders, Nicola Savory, Beck Taylor, Kate Jolly","doi":"10.1111/mcn.70115","DOIUrl":"https://doi.org/10.1111/mcn.70115","url":null,"abstract":"<p><p>The assets-based feeding help before and after birth (ABA-feed) intervention aims to improve breastfeeding rates by offering proactive peer support to first-time mothers, regardless of feeding intention. Based on behaviour change theory and an assets-based approach, the intervention involved training existing peer supporters to become infant feeding helpers (IFHs). A train-the-trainer model was used, with coordinators delivering four 2-h training sessions to IFHs. Training covered a study overview, IFH role, role-play scenarios and signposting to local assets. Due to COVID-19, training was delivered online. Post-training questionnaires were completed by 22/30 (73.3%) coordinators and 119/193 (61.7%) IFHs, and qualitative interviews were conducted with 24 coordinators and 72 IFHs. Researchers observed training at five sites, assessing fidelity, engagement and delivery quality. Questionnaire data were analysed descriptively, and qualitative data were analysed using framework analysis. Findings indicated that coordinators valued the train-the-trainer model, particularly information on formula feeding and antenatal discussions. IFHs found training engaging and felt prepared, though some were apprehensive about formula feeding support. While online training was convenient, challenges included monitoring discussions and role-play in breakout rooms. Most participants favoured a hybrid approach, with in-person sessions for interactive activities. Observations showed high training fidelity, participant engagement and confidence in delivering intervention components. The ABA-feed training was acceptable to coordinators and IFHs and was delivered with fidelity. Future training should adopt a hybrid approach, incorporating diverse resources and prioritising in-person interactive components such as role-play. Trial Registration: ISRCTN17395671.</p>","PeriodicalId":51112,"journal":{"name":"Maternal and Child Nutrition","volume":" ","pages":"e70115"},"PeriodicalIF":2.6,"publicationDate":"2025-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145103069","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Informal Human Milk Sharing Practices: A Cross-Sectional Survey of Donors and Recipients in Ireland.","authors":"Niamh Vickers, Anne Matthews, Gillian Paul","doi":"10.1111/mcn.70113","DOIUrl":"https://doi.org/10.1111/mcn.70113","url":null,"abstract":"<p><p>The provision of human milk is a global public health priority underpinned by its extensive benefits to infant and maternal health, and significant positive impacts within economic, societal, and environmental spheres. Informal human milk sharing (IHMS) is a contemporary and increasingly prevalent phenomenon which involves the exchange of human milk outside formal structures such as milk banks. This study aimed to investigate the characteristics, motivations, practices and experiences of donors and recipients who engage in IHMS in Ireland. A national cross-sectional survey included a validated questionnaire and was administered online in Ireland following ethical approval. The study is reported according to STROBE guidelines. Recipients reported significantly higher rates of cesarean sections, birth complications, and traumatic births compared to donors, with postpartum anxiety prevalent in both donors and recipients (51.4%). Recipients primarily sought donor milk due to perceived lactation insufficiency, concerns regarding commercial milk formula, infant related factors and belief in human milk benefits. Donors were motivated by altruism and the desire not to waste their expressed milk. Most donors (84.5%) considered formal milk bank donations but were inhibited by practical barriers, favoring informal sharing via online platforms and direct exchanges. There was minimal discussions with healthcare professionals about IHMS. The increasing significance of IHMS in Ireland is driven by diverse maternal and infant needs, and online communities. Future research should investigate safety outcomes and long-term impacts of IHMS, the lived experiences of donors and recipients, as well as the examination of strategies to enhance engagement with formal milk banks.</p>","PeriodicalId":51112,"journal":{"name":"Maternal and Child Nutrition","volume":" ","pages":"e70113"},"PeriodicalIF":2.6,"publicationDate":"2025-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145088120","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Breastfeeding and Water Security","authors":"Rafael Pérez-Escamilla,&nbsp;Victoria Hall Moran","doi":"10.1111/mcn.70114","DOIUrl":"10.1111/mcn.70114","url":null,"abstract":"&lt;p&gt;Water security has been defined by the United Nations as “&lt;i&gt;The capacity of a population to safeguard sustainable access to adequate quantities of acceptable quality water for sustaining livelihoods, human well-being, and socioeconomic development, for ensuring protection against water-borne pollution and water-related disasters, and for preserving ecosystems in a climate of peace and political stability”&lt;/i&gt; (United Nations &lt;span&gt;2013&lt;/span&gt;). As such, water security is crucial for human and planetary health and the development of nations. As addressed at the 2025 World Water Week held in Stockholm August 24-28, climate change has become a formidable challenge for water security globally. In this editorial we make the case that investing in breastfeeding protection, promotion and support should be a key component of national and global strategies to address water insecurity.&lt;/p&gt;&lt;p&gt;Global recommendations call for infants to be exclusively breastfed for 6 months, making breastmilk is the only source of water for infants of this age. As over 85% of breastmilk is water, babies can indeed meet their water needs through breastfeeding (Martin et al. &lt;span&gt;2016&lt;/span&gt;). Once complementary foods are introduced at around 6 months infants are recommended to continue to breastfeed for at least their first 2 years of life, hence breast milk can also be an important source of water security for infants and toddlers beyond the first 6 months of life.&lt;/p&gt;&lt;p&gt;It is estimated that 2,562.5 billion liters of water are used every year in the production and use of commercial milk formula (CMF) by infants under 6 months (Smith et al. &lt;span&gt;2024&lt;/span&gt;). Therefore, investing in breastfeeding protection, promotion and support can reduce substantially the use of water across the globe. Climate change mitigation requires bringing down the levels of greenhouse gases (GHG) which mainly come from industrial activity. The CMF industry generates between 5.9 and 7.5 billion kg CO2 eq. every year because of environmental degradation and fossil fuel use related to dairy farming, milk processing, and CMF production, transportation, storage and preparation. Exclusive breastfeeding, in contrast, produces a far lower carbon footprint compared to feeding with CMF (Andresen et al. &lt;span&gt;2022&lt;/span&gt;; Karlsson et al. &lt;span&gt;2019&lt;/span&gt;). The massive impact of the CMF industry on climate change and water use is evident at the country level. Using India as an example, CMF consumption among infants under 6 months utilizes 250.6 billion liters of water and GHG emissions range from 579 to 737 million kg CO2 eq. annually, despite the country's high breastfeeding prevalence among infants under 6 months (Smith et al. &lt;span&gt;2024&lt;/span&gt;). For this reason, it has been recommended for breastfeeding to be included in climate change mitigation agreements and investments within countries and across the globe (Smith et al. &lt;span&gt;2024&lt;/span&gt;) (Figure 1).&lt;/p&gt;&lt;p&gt;Moreover, climate change is driving an inc","PeriodicalId":51112,"journal":{"name":"Maternal and Child Nutrition","volume":"21 4","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/mcn.70114","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145076592","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Overview: Existing Context and the Need to Generate Evidence of the Impact of Large-Scale Food Fortification on the Prevalence of Anemia.","authors":"Manpreet Chadha, Daniel Lopez de Romana, Helena Pachón, Mandana Arabi","doi":"10.1111/mcn.70093","DOIUrl":"https://doi.org/10.1111/mcn.70093","url":null,"abstract":"","PeriodicalId":51112,"journal":{"name":"Maternal and Child Nutrition","volume":" ","pages":"e70093"},"PeriodicalIF":2.6,"publicationDate":"2025-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145066539","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}