Journal of Sexual Medicine最新文献

{"title":"Prospective study of endogenous testosterone recovery following neoadjuvant hormonal blockade and radical prostatectomy in high-risk prostate cancer patients.","authors":"Bruno Chiesa G Nascimento, Rubens Pedrenho, Pedro C E Zandoná, Lucas V Sanvido, José Bessa Junior, Eduardo de P Miranda, Diogo A Bastos, Mauricio D Cordeiro, Rafael Coelho, William C Nahas, Jorge Hallak, John P Mulhall, Cristiano M Gomes","doi":"10.1093/jsxmed/qdaf164","DOIUrl":"https://doi.org/10.1093/jsxmed/qdaf164","url":null,"abstract":"<p><strong>Background: </strong>Recovery of endogenous testosterone following androgen deprivation therapy (ADT) for prostate cancer is uncertain.</p><p><strong>Aim: </strong>To prospectively evaluate testosterone (T) recovery rates and timing after neoadjuvant ADT followed by radical prostatectomy (RP).</p><p><strong>Methods: </strong>We report a secondary analysis from a phase II randomized trial involving 64 patients who received a 3-month neoadjuvant ADT regimen (goserelin, abiraterone with prednisone and for half of the participants, apalutamide) followed by RP. Total Testosterone (TT) was measured at baseline, during ADT (3 m), and after 4, 8, and 12 months post-ADT cessation. Return to non-castrate levels (TT > 50 ng/dL), to normal (TT ≥ 300 ng/dL), and back to baseline level (BTB, defined as TT ≥ baseline) are reported. Predictive factors were analyzed using uni and multivariate analyses (MVA), and quality of life (QoL) was assessed with the validated Expanded Prostate Cancer Index Composite (EPIC-50).</p><p><strong>Outcomes: </strong>Chance and chronology of T recovery 1 year after ADT cessation.</p><p><strong>Results: </strong>Median T levels were as follows: baseline 442 ng/dL (IQR: 321-505); 4 months post-ADT, 144 ng/dL (IQR: 35-284); 8 months, 316 ng/dL (IQR: 243-438); and 12 months, 358 ng/dL (IQR: 285-477). By 12 months, 98.1% of patients reached non-castrate levels, 79.5% returned to normal, and 33.9% to BTB. Half of the patients achieved T > 50 ng/dL in 5 months, T ≥ 300 ng/dL in 9.1 months, and BTB in 13.1 months. In MVA, baseline T was the only significant predictor for T normalization (OR: 1.015; P < .01), while age and baseline T were predictors for BTB recovery (OR for age: 0.88; P = .02; OR for baseline T: 0.99; P = .02). QoL assessment showed persistently low sexual function, with minor improvements over time (median scores: 0 [0-5.6] at 4 months and 2.8 [0-29.2] at 12 months, P < .01), while sexual bother starts very low but significantly increases during follow up (median scores: 100 [IQR: 42.2-100] at 4 months to 50 [IQR: 0-100] at 12 months, P = .03).</p><p><strong>Clinical implications: </strong>Long-term lower T levels can occur even after short-term ADT, persisting longer than anticipated. Clinicians should consider this in patient management.</p><p><strong>Strengths and limitations: </strong>Our strengths include the prospective, controlled design and a rarely reported ADT triple therapy followed by RP. Limitations include the use of immunoassay to measure TT.</p><p><strong>Conclusion: </strong>After 3 months of neoadjuvant triple ADT and RP, significant recovery to non-castrate and normal T levels is seen in most patients by 1 year; yet, BTB recovery is achieved in only a third. Higher baseline T and younger age predict faster T normalization and BTB recovery, respectively.</p>","PeriodicalId":51100,"journal":{"name":"Journal of Sexual Medicine","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2025-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144692351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Letter to the Editor on \"Examining gender-specific mental health risks after gender-affirming surgery: a national database study\".","authors":"Zeki Bayraktar","doi":"10.1093/jsxmed/qdaf162","DOIUrl":"https://doi.org/10.1093/jsxmed/qdaf162","url":null,"abstract":"","PeriodicalId":51100,"journal":{"name":"Journal of Sexual Medicine","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2025-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144692345","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"New comprehension on polycystic ovary syndrome and sexual function: a systematic review and meta-analysis.","authors":"Fernanda S Bachega, José Antônio O Turri, Maria Cândida P Baracat, Ricardo Santos Simões, Gustavo A R Maciel, Roger A Lobo, José Maria Soares, Edmund Chada Baracat","doi":"10.1093/jsxmed/qdaf163","DOIUrl":"https://doi.org/10.1093/jsxmed/qdaf163","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;Polycystic ovary syndrome (PCOS), a prevalent endocrine disorder characterized by menstrual irregularities and hyperandrogenic manifestations, has been increasingly associated with psychological distress and impaired self-image. However, results regarding sexual function (SF) in PCOS women are still controversial, and their interpretation is complicated by the use of different SF assessment tools across studies.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Aim: &lt;/strong&gt;To evaluate female sexual dysfunction in PCOS women diagnosed through modified Rotterdam criteria by conducting specific meta-analyses for each validated SF questionnaire and assess the influence of overweight/obesity (OW/O) on these outcomes.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;A Systematic Review (PRISMA) of 8 databases was performed until March 2024. Meta-analysis employed STATA software, employing a random-effects model to compare groups via Hedges' g and standardized mean difference (SMD). Heterogeneity (I2 statistic; Q test) and publication bias (funnel plots; Egger's test) were assessed.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Outcomes: &lt;/strong&gt;The influence of PCOS and OW/O on SF.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;A total of 6171 articles were initially screened, and 40/6171 studies were included in this systematic review. Meta-analyses were performed solely for the Female Sexual Function Index (FSFI) score as it was the only SF assessment tool widely used across published studies. Pooled meta-analysis results showed that PCOS women had significantly lower FSFI scores in all fields than controls: total FSFI: -0.4 (95% CI -0.45; -0.36, I2 = 94.3%); desire: -0.22 (95% CI -0.26; -0.17, I2 = 90.8%); arousal: -0.3 (95% CI -0.34; -0.25, I2 = 94.1%); lubrication: -0.31 (95% CI -0.36; -0.26, I2 = 93%); orgasm: -0.27 (95% CI -0.32; -0.22 I2 = 89.2%); satisfaction: -0.23 (95% CI -0.28; -0.18, I2 = 81.5%); pain: -0.3 (95% CI -0.35; -0.25, I2 = 91.1%). OW/O PCOS women scored with higher lubrication scores than OW/O controls (SMD = 0.3 95% CI [0.03;0.58], P = .02, I2 = 0%).&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Clinical translation: &lt;/strong&gt;These findings emphasize the importance of incorporating SF assessments into PCOS follow-up protocols and multidisciplinary care.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Strengths and limitations: &lt;/strong&gt;Strengths include a large cohort, analysis of an OW/O subgroup, and robust quality assessment using the Newcastle-Ottawa Scale. The main limitation was the lack of published studies using SF-assessment tools other than the FSFI, which precluded meta-analyses for other questionnaires.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusion: &lt;/strong&gt;While PCOS women experience significantly impaired SF than controls, those with OW/O and PCOS may have comparable or even enhanced SF in certain domains, particularly lubrication, suggesting that the interplay between obesity and SF in PCOS women may not always be negative. By integrating routine screening with a multidisciplinary approach, we can more effectively address the sexual health challenges faced by P","PeriodicalId":51100,"journal":{"name":"Journal of Sexual Medicine","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2025-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144692348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Letter to the Editor on \"Examining gender-specific mental health risks after gender-affirming surgery: a national database study\".","authors":"Chan Kulatunga-Moruzi, Irina Dinu, Ari R Joffe","doi":"10.1093/jsxmed/qdaf160","DOIUrl":"https://doi.org/10.1093/jsxmed/qdaf160","url":null,"abstract":"","PeriodicalId":51100,"journal":{"name":"Journal of Sexual Medicine","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2025-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144692344","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Response to Letter to the Editor on \"Examining gender-specific mental health risks after gender-affirming surgery: a national database study\".","authors":"Joshua E Lewis","doi":"10.1093/jsxmed/qdaf161","DOIUrl":"https://doi.org/10.1093/jsxmed/qdaf161","url":null,"abstract":"","PeriodicalId":51100,"journal":{"name":"Journal of Sexual Medicine","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2025-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144692352","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Novel insights of vulvodynia pathophysiology from reliable and comprehensive pelvic floor muscle surface electromyography characterization: can it help predict response to botulinum toxin treatment?","authors":"Monica Albaladejo-Belmonte, Paula Villa-Muñoz, Francisco Jose Nohales-Alfonso, Blanca Novillo-Del Álamo, Jose Alberola-Rubio, Javier Garcia-Casado","doi":"10.1093/jsxmed/qdaf171","DOIUrl":"https://doi.org/10.1093/jsxmed/qdaf171","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;Findings on vulvodynia-associated alterations in the pelvic floor muscles' (PFMs') myoelectrical activity are contradictory, and no study has yet assessed whether they influence treatment outcomes.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Aim: &lt;/strong&gt;To characterize vulvodynia-associated alterations in PFM activity and assess its potential to predict the response to botulinum toxin type A (BoNT/A) treatment.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;This prospective, non-masked, and non-randomized study recruited 35 vulvodynia patients who underwent BoNT/A injections and 35 healthy women. Their left and right PFM activity was monitored by surface electromyography (sEMG) with 2 recording modalities (intravaginal probe and external electrodes) during PFM contractions and rest and compared across groups at baseline. Clinical information was also collected from their medical history, pelvic physical examination, and self-informed clinical questionnaires. Both sEMG and clinical features were used to predict the patient's response to treatment using multiple binary logistic regression models.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Outcomes: &lt;/strong&gt;sEMG signals' root mean square (RMS), median frequency (MDF), sample entropy (SampEn), intramuscular and intermuscular magnitude-squared coherence (mscoh) and imaginary part of their coherency (iCOH), and clinical outcomes (sociodemographic, obstetric, gynecological, urological, and other general clinical characteristics; painful comorbidities; pelvic and vulvar pain sensitivity; Patient's Global Impression of Improvement).&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;Vulvodynia patients exhibited significantly lower intensity during contractions (&lt;RMS, P = .003) and altered intramuscular coupling (&gt;mscoh) during contractions (P = .004) and rest (P = .006) in the myoelectrical activity of their left superficial PFM (sEMG from external electrodes) and altered intermuscular coupling during contractions (&gt;mscoh, P = .004) in their deep PFM (sEMG from intravaginal probe) than healthy women. Furthermore, intramuscular coupling at rest was significantly associated with response to treatment (P &lt; .01) and predicted it accurately when combined with clinical information (AUC = 0.95).&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Clinical implications: &lt;/strong&gt;PFM sEMG can provide valuable insights into vulvodynia pathophysiology and help optimize treatment selection, potentially reducing the economic and psychological impact of ineffective treatment.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Strengths and limitations: &lt;/strong&gt;This study provides a reliable and comprehensive description of PFM myoelectrical activity alterations in vulvodynia conditions, demonstrating for the first time that sEMG information can improve the prediction of treatment response. It is limited by a small sample size of intravaginal probe recordings due to pain elicited by probes during their insertion and signal quality.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusion: &lt;/strong&gt;Vulvodynia is associated with decreased activity intensity in the superficial PFM a","PeriodicalId":51100,"journal":{"name":"Journal of Sexual Medicine","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2025-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144668984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Maximizing postoperative satisfaction in penile prosthesis surgery: the predictive power of preoperative length and its role in tailoring enhancement procedures.","authors":"Mohamed Abdelwahab, Adham AbdelKader, Mohamed Abdelrassoul, Waleed Ghonema, Mohamed Aboelfotooh, Amr Lotfi, Galal ElShorbagy","doi":"10.1093/jsxmed/qdaf169","DOIUrl":"https://doi.org/10.1093/jsxmed/qdaf169","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;Penile prosthesis implantation (PPI) is a common procedure for refractory erectile dysfunction (ED). Changes in penile size affect patient satisfaction.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Aim: &lt;/strong&gt;To evaluate the predictive value of preoperative penile length measurements for postoperative sexual satisfaction following PPI, with or without lengthening procedures.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Outcomes: &lt;/strong&gt;Postoperative satisfaction and penile length were evaluated at 3 months using both objective measurements and patient-reported assessments.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;This prospective, randomized comparative study included 61 male patients with organic vascular ED refractory to medical treatment. Patients were divided into two groups:Group A (n = 31): Underwent suspensory ligament release (SLR) with lower penopubic Z-plasty, dorsal and ventral phalloplasty.Group B (n = 30): Underwent PPI alone via a ventral midline penoscrotal incision.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;The mean functional and visible penile lengths were significantly greater in Group A compared to Group B (P &lt; .001 for both). The erectile dysfunction inventory of treatment satisfaction (EDITS) resting-state score was also significantly higher in Group A (55.2%) than in Group B (0.0%) (P &lt; .001). A preoperative Functional Stretched Penile Length (FSPL) cutoff of 12.75 cm in Group A predicted postoperative satisfaction with 81.8% sensitivity and 71.4% specificity, while in Group B, a cutoff of 14.50 cm yielded 77.8% sensitivity and 94.7% specificity. Similarly, a Visible Stretched Penile Length (VSPL) cutoff of 10.75 cm in Group A predicted satisfaction with 81.8% sensitivity and 71.4% specificity, and a cutoff of 12.50 cm in Group B predicted satisfaction with 66.7% sensitivity and 94.7% specificity.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Clinical implications: &lt;/strong&gt;Preoperative penile length serves as a predictor of postoperative satisfaction; patients with shorter lengths may benefit from adjunctive lengthening procedures, provided that risks are carefully weighed and thorough preoperative counseling is conducted to align expectations and optimize outcomes.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Strengths & limitations: &lt;/strong&gt;This is the first study to establish preoperative penile length cutoffs predictive of postoperative satisfaction; while its randomized design strengthens validity, limitations include small sample size, single-center setting, lack of participant blinding, and exclusive evaluation of malleable implants, which may reduce clinical applicability and limit generalizability beyond high-volume surgeons performing SLR.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusions: &lt;/strong&gt;A preoperative FSPL of &lt;12.75 cm or VSPL of &lt;10.75 cm identifies patients most likely to benefit from concomitant lengthening procedures, while those exceeding these thresholds may achieve satisfactory outcomes without augmentation; thus, preoperative assessment of functional and visible stretched penile lengths serves as a valuable predictor of ","PeriodicalId":51100,"journal":{"name":"Journal of Sexual Medicine","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2025-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144668983","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Peyronie's disease and risk of depression. A nationwide 25-year cohort study.","authors":"Sophie Løfvall Lindhardt-Mejlholm, Katrine Schmidt Mortensen, Ina Trolle Andersen, Mette Nørgaard, Lars Lund","doi":"10.1093/jsxmed/qdaf168","DOIUrl":"https://doi.org/10.1093/jsxmed/qdaf168","url":null,"abstract":"<p><strong>Background: </strong>Peyronie's disease leads to penile deformities and can cause physical symptoms, for example, penile pain, and erectile dysfunction, along with psychological issues, such as depressive symptoms.</p><p><strong>Aim: </strong>The aim of this study was to investigate whether men with Peyronie's disease have an increased risk of depression.</p><p><strong>Methods: </strong>This nationwide cohort study included men with Peyronie's disease (ICD-10 code: N486) from 1997 to 2021 and age-matched (1:10) men without Peyronie's disease. We obtained complete medical history before the Peyronie's disease diagnosis/index date. We followed both cohorts for depression. We computed the cumulative incidence of depression at 5 and 10 years of follow-up and estimated hazard ratios for depression comparing the 2 cohorts while adjusting for selected chronic diseases using Cox regression.</p><p><strong>Outcome: </strong>The primary outcome, depression, was defined by ICD-10 code: F32, F33 recorded in the Danish National Patient Registry or the Psychiatric Central Research Registry and/or redemption of at least 2 prescriptions for an antidepressant (ATC-code: N06A).</p><p><strong>Results: </strong>We included 10 053 men with Peyronie's disease and 100 530 without (median age 55.6 years). At the index date, 19.6% men with Peyronie's disease had depression versus 14.0% men without. At baseline, men with Peyronie's disease had a 5-year risk of depression of 7.0% versus 4.4% in men without, while the 10-year risks were 12.5% and 8.7%, respectively. The adjusted hazard ratio was 1.42 (95% CI, 1.32, 1.52).Men with Peyronie's disease had a 10-year all-cause mortality of 5.9%, while it was 9.1% in men without.</p><p><strong>Clinical implications: </strong>Health professionals should ensure that men with Peyronie's disease are examined for depression.</p><p><strong>Strengths and limitations: </strong>A limitation of our study is the potential underdiagnosis of men with Peyronie's disease, which may lead to an incorrect estimation of depression among Peyronie's disease patients. It is a strength that we include a nationwide cohort of men with Peyronie's disease and age-matched controls. Other strengths are that we included information from several Danish medical databases and depression was defined as a clinic diagnosis and/or redemption of at least 2 prescriptions for an antidepressant.</p><p><strong>Conclusions: </strong>Men with Peyronie's disease had a higher prevalence of depression at the time of diagnosis and a higher risk of depression following diagnosis compared with men without.</p>","PeriodicalId":51100,"journal":{"name":"Journal of Sexual Medicine","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2025-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144668985","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Insertion of erectile device following phalloplasty in individuals assigned male at birth: a systematic review.","authors":"Karl H Pang, Nim Christopher, David J Ralph, Wai Gin Lee","doi":"10.1093/jsxmed/qdaf019","DOIUrl":"https://doi.org/10.1093/jsxmed/qdaf019","url":null,"abstract":"<p><strong>Introduction: </strong>Erectile devices can be used to achieve erectile rigidity after phalloplasty in assigned male at birth (AMAB) individuals for congenital or acquired penile inadequacy. The insertion technique in a neophallus is different and more challenging compared to that of an anatomical penis.</p><p><strong>Objective: </strong>To perform a systematic review, summarizing the literature on the insertion of erectile devices in the neophallus of individuals AMAB focusing on techniques, types of devices used, postoperative complications and patient reported outcomes.</p><p><strong>Method: </strong>The review was performed according to the PRISMA statement. A search of the PubMed database was performed on June 17, 2023 (updated on September 11, 2024) retrieving 86 articles. Overall, 15 studies fulfilled the inclusion criteria and were included in the analysis.</p><p><strong>Results: </strong>184 AMAB individuals had an erectile device inserted. The indications for phalloplasty were penile inadequacy secondary to bladder exstrophy-epispadias complex (46.5%), penile cancer (18.6%), trauma (16.7%), disorder of sex differentiation or micropenis/hypospadias (14.7%), male-female reversal (2.7%), and infection (0.8%). A radial artery forearm free flap was used in 91.1% of patients. The AMS 700 inflatable prosthesis was the most common device inserted. Most studies used a graft to cover the distal cylinder tips to reduce the risk of erosion. Up to 64.3% of patients experienced a complication. Infection, mechanical failure/dysfunction, and malposition/migration/under-sizing occurred in up to 33.3%, 28.6% and 40%, respectively. Explantation was required in up to 40% of patients for erosion. Up to 33.3% of patients had their erectile device revised or replaced. Overall, 80%-100% were satisfied with the outcomes.</p><p><strong>Conclusion: </strong>Erectile device insertion in AMAB individuals following phalloplasty for penile inadequacy is an acceptable and satisfying option to achieve rigidity for sexual intercourse. However, this is a challenging procedure associated with significant risks of complication.</p>","PeriodicalId":51100,"journal":{"name":"Journal of Sexual Medicine","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2025-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144627690","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring sexual education among adults with muscular dystrophies.","authors":"Jisoo Kim, Alyssa Rohan, Robin E Margolin, Aleah Pagan, Nessa Tantivit, Nasra Jama, Ellis Barrera, John M Baronas, Elizabeth R Boskey, Nora E Renthal","doi":"10.1093/jsxmed/qdaf155","DOIUrl":"https://doi.org/10.1093/jsxmed/qdaf155","url":null,"abstract":"","PeriodicalId":51100,"journal":{"name":"Journal of Sexual Medicine","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2025-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144602177","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}