Journal of PainPub Date : 2025-01-03DOI: 10.1016/j.jpain.2024.104774
Marelle K Wilson, Dianne J Wilson, Amelia K Searle, Shylie F Mackintosh
{"title":"Consumer perspectives of the group itself in group-delivered programs for people with chronic pain: A systematic review and meta-synthesis.","authors":"Marelle K Wilson, Dianne J Wilson, Amelia K Searle, Shylie F Mackintosh","doi":"10.1016/j.jpain.2024.104774","DOIUrl":"10.1016/j.jpain.2024.104774","url":null,"abstract":"<p><p>Group-delivered programs for chronic pain are evidence-based and frequently used. The contribution of group factors to outcomes is unclear and there are no integrated findings on consumer perceptions of the group itself in programs for people with chronic pain. The aim of this systematic review was to search and synthesise qualitative data specifically related to the group itself in studies investigating group-delivered programs for people with chronic pain (PROSPERO, CRD42023382447). MEDLINE, EMBASE, EmCare, PsycINFO, Scopus, and CINAHL databases were searched, and qualitative studies that explored the experiences of consumers who had attended any style of group-delivered program for people with chronic pain were included. Methodological quality was assessed using the Critical Appraisal Skills Programme checklist and meta-synthesis was guided by a thematic synthesis approach. Ninety-three studies were included, with 1806 participants. Programs were predominantly multi-component, with diverse interventions and facilitators. Three analytical themes were generated: (1) Peer interaction: a program component in and of itself; (2) Comparison: frequently used and mostly helpful; and (3) Beyond the program: when the group itself contributes to change. Findings highlighted that most consumers valued the group itself, finding interaction, and comparing themselves with peers useful. Future research related to group factors in programs for people with chronic pain should include consumer participation and co-design. PERSPECTIVE: This review demonstrates that many consumers valued peer interaction and used comparison-based cognitive processing within group-delivered programs for chronic pain. Dialogue-based interactions with similar others promoted cognitive, affect, and behaviour changes. Group factors may have been underestimated and outcomes could be influenced if peer interactions within programs were optimised.</p>","PeriodicalId":51095,"journal":{"name":"Journal of Pain","volume":" ","pages":"104774"},"PeriodicalIF":4.0,"publicationDate":"2025-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142933371","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Journal of PainPub Date : 2025-01-03DOI: 10.1016/j.jpain.2025.104775
Tahmina Begum , Bhagyavalli Veeranki , Ogenna Joy Chike , Suzanne Tamang , Julia F. Simard , Jonathan Chen , Yashaar Chaichian , Sean Mackey , Beth D. Darnall , Titilola Falasinnu
{"title":"Refining chronic pain phenotypes: A comparative analysis of sociodemographic and disease-related determinants using electronic health records","authors":"Tahmina Begum , Bhagyavalli Veeranki , Ogenna Joy Chike , Suzanne Tamang , Julia F. Simard , Jonathan Chen , Yashaar Chaichian , Sean Mackey , Beth D. Darnall , Titilola Falasinnu","doi":"10.1016/j.jpain.2025.104775","DOIUrl":"10.1016/j.jpain.2025.104775","url":null,"abstract":"<div><div>The use of electronic health records (EHR) for chronic pain phenotyping has gained significant attention in recent years, with various algorithms being developed to enhance accuracy. Structured data fields (e.g., pain intensity, treatment modalities, diagnosis codes, and interventions) offer standardized templates for capturing specific chronic pain phenotypes. This study aims to determine which chronic pain case definitions derived from structured data elements achieve the best accuracy, and how these validation metrics vary by sociodemographic and disease-related factors. We used EHR data from 802 randomly selected adults with autoimmune rheumatic diseases seen at a large academic center in 2019. We extracted structured data elements to derive multiple phenotyping algorithms. We confirmed chronic pain case definitions via manual chart review of clinical notes, and assessed the performance of derived algorithms, e.g., sensitivity/recall, specificity, positive predictive value (PPV). The highest sensitivity (67%) was observed when using ICD codes alone, while specificity peaked at 96% with a quadrimodal algorithm combining pain scores, ICD codes, prescriptions, and interventions. Specificity was generally higher in males and younger patients, particularly those aged 18–40 years, and highest among Asian/Pacific Islander and privately insured patients. PPV was highest among patients who were female, younger, or privately insured. PPV and sensitivity were lowest among males, Asian/Pacific Islander, and older patients. Variability of phenotyping results underscores the importance of refining chronic pain phenotyping algorithms within EHRs to enhance their accuracy and applicability. While our current algorithms provide valuable insights, enhancement is needed to ensure more reliable chronic pain identification across diverse patient populations.</div></div><div><h3>Perspectives</h3><div>This study evaluates chronic pain phenotyping algorithms using electronic health records, highlighting variability in performance across sociodemographic and disease-related factors. By combining structured data elements, the findings advance chronic pain identification, promoting equitable healthcare practices and highlighting the need for tailored algorithms to address subgroup-specific biases and improve outcomes.</div></div>","PeriodicalId":51095,"journal":{"name":"Journal of Pain","volume":"28 ","pages":"Article 104775"},"PeriodicalIF":4.0,"publicationDate":"2025-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142933468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Journal of PainPub Date : 2025-01-01DOI: 10.1016/j.jpain.2024.104755
Caterina Grano
{"title":"Reply to Letter to Editor by Bordoni Bruno, regarding Pain severity and depressive symptoms in endometriosis patients: Mediation of negative body awareness and interoceptive self-regulation","authors":"Caterina Grano","doi":"10.1016/j.jpain.2024.104755","DOIUrl":"10.1016/j.jpain.2024.104755","url":null,"abstract":"","PeriodicalId":51095,"journal":{"name":"Journal of Pain","volume":"26 ","pages":"Article 104755"},"PeriodicalIF":4.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142808483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Journal of PainPub Date : 2025-01-01DOI: 10.1016/j.jpain.2024.104708
Jiaxin An , Wei Fan , Anant Mittal , Yan Zhang , Annie T. Chen
{"title":"Corrigendum to “Mobile app use among persons with fibromyalgia: a cross-sectional survey” [J Pain, Volume 25, Issue 8, August 2024, 104515]","authors":"Jiaxin An , Wei Fan , Anant Mittal , Yan Zhang , Annie T. Chen","doi":"10.1016/j.jpain.2024.104708","DOIUrl":"10.1016/j.jpain.2024.104708","url":null,"abstract":"","PeriodicalId":51095,"journal":{"name":"Journal of Pain","volume":"26 ","pages":"Article 104708"},"PeriodicalIF":4.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142565176","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Journal of PainPub Date : 2025-01-01DOI: 10.1016/j.jpain.2024.104666
Arnas Tamasauskas , Barbara Silva-Passadouro , Nicholas Fallon , Bernhard Frank , Svajune Laurinaviciute , Simon Keller , Andrew Marshall
{"title":"Management of Central Poststroke Pain: Systematic Review and Meta-analysis","authors":"Arnas Tamasauskas , Barbara Silva-Passadouro , Nicholas Fallon , Bernhard Frank , Svajune Laurinaviciute , Simon Keller , Andrew Marshall","doi":"10.1016/j.jpain.2024.104666","DOIUrl":"10.1016/j.jpain.2024.104666","url":null,"abstract":"<div><div>Central poststroke pain (CPSP) is a neuropathic pain condition prevalent in 8 to 35% of stroke patients. This systematic review and meta-analysis aimed to provide insight into the effectiveness of available pharmacological, physical, psychological, and neuromodulation interventions in reducing pain in CPSP patients (PROSPERO Registration: CRD42022371835). Secondary outcomes included mood, sleep, global impression of change, and physical responses. Data extraction included participant demographics, stroke etiology, pain characteristics, pain reduction scores, and secondary outcome metrics. Forty-two original studies were included, with a total of 1,451 participants. No studies providing psychological therapy to CPSP patients were identified. Twelve studies met requirements for a random-effects meta-analyses that found pharmacological therapy to have a small effect on mean pain score (SMD = −.36, 96.0% confidence interval [−.68, −.03]), physical interventions did not show a significant effect (SMD = −.55 [−1.28, .18]), and neuromodulation treatments had a moderate effect (SMD = −.64 [−1.08, −.19]). Fourteen studies were included in proportional meta-analysis with pharmacological studies having a moderate effect (58.3% mean pain reduction [−36.51, −80.15]) and neuromodulation studies a small effect (31.1% mean pain reduction [−43.45, −18.76]). Sixteen studies were included in the narrative review, the findings from which largely supported meta-analysis results. Duloxetine, amitriptyline, and repetitive transcranial magnetic stimulation had the most robust evidence for their effectiveness in alleviating CPSP-induced pain. Further multicenter placebo-controlled research is needed to ascertain the effectiveness of physical therapies, such as acupuncture and virtual reality, and invasive and noninvasive neuromodulation treatments.</div></div><div><h3>Perspective</h3><div>This article presents a top-down and bottom-up overview of evidence for the effectiveness of different pharmacological, physical, and neuromodulation treatments of CPSP. This review could provide clinicians with a comprehensive understanding of the effectiveness and tolerability of different treatment types.</div></div>","PeriodicalId":51095,"journal":{"name":"Journal of Pain","volume":"26 ","pages":"Article 104666"},"PeriodicalIF":4.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142300219","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Journal of PainPub Date : 2025-01-01DOI: 10.1016/j.jpain.2024.104731
Bruno Bordoni
{"title":"Letter to Editor: Pelvic floor and diaphragm","authors":"Bruno Bordoni","doi":"10.1016/j.jpain.2024.104731","DOIUrl":"10.1016/j.jpain.2024.104731","url":null,"abstract":"","PeriodicalId":51095,"journal":{"name":"Journal of Pain","volume":"26 ","pages":"Article 104731"},"PeriodicalIF":4.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142632104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Journal of PainPub Date : 2024-12-31DOI: 10.1016/j.jpain.2024.104771
Inge Timmers , Lauren E. Harrison , Laura E. Simons
{"title":"Seeing your child in pain: Parent empathy in the context of their child’s chronic pain","authors":"Inge Timmers , Lauren E. Harrison , Laura E. Simons","doi":"10.1016/j.jpain.2024.104771","DOIUrl":"10.1016/j.jpain.2024.104771","url":null,"abstract":"<div><div>Observing your child in pain is inherently distressing. In the context of chronic pain, caregiver responses can powerfully impact child pain-related functioning. The Parent Empathy in the Context of Pain model postulates that parent empathic distress may hinder adaptive responses to child pain, thus playing a key role in the link between parent responses and child functioning. Here, we examined how parent empathy is related to parent and child pain-related constructs within the Parent Empathy in the Context of Pain model, using an adapted Empathy for Pain Scale (EPS) for use in parents (P-EPS). Data were collected from 190 parents of youth with chronic pain (170 mothers; children aged 8–18y) and their children. Structural equation modeling (SEM) showed support for the theoretical model. Parent pain-related beliefs were associated with behavioral responses via affective responses of empathy for pain (affective distress) and emotion regulation (emotional suppression), which in turn were associated with child pain-related functioning. Moreover, higher levels of parent empathic distress to observing their child’s pain was significantly associated with more general empathic distress, poorer perspective taking and more maladaptive emotion regulation strategy use (emotional suppression). Our findings underscore the involvement of parent affective responses in driving parent maladaptive behavioral responses to their child’s pain and emphasize the role of affective empathic distress as well as its regulation. In addition to providing information on its assessment, this empirical investigation provides novel insights into the construct of empathy in this context.</div></div><div><h3>Perspective</h3><div>This article presents initial data supporting the Parent Empathy in the Context of Pain model. Findings show involvement of parent affective responses in driving parent maladaptive behavioral responses to their child’s chronic pain and emphasize the role of affective empathic distress as well as its regulation.</div></div>","PeriodicalId":51095,"journal":{"name":"Journal of Pain","volume":"28 ","pages":"Article 104771"},"PeriodicalIF":4.0,"publicationDate":"2024-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142924004","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Journal of PainPub Date : 2024-12-28DOI: 10.1016/j.jpain.2024.104772
KayLoni Olson PhD , Ruth A. Hackett , Whitney Scott
{"title":"Weight discrimination partially mediates the longitudinal relationship between Body Mass Index and pain","authors":"KayLoni Olson PhD , Ruth A. Hackett , Whitney Scott","doi":"10.1016/j.jpain.2024.104772","DOIUrl":"10.1016/j.jpain.2024.104772","url":null,"abstract":"<div><div>Pain is common among individuals with high Body Mass Index (BMI). This study investigated weight discrimination as a mediator of the longitudinal relationship between BMI and the presence of moderate/severe pain among adults from the English Longitudinal Study of Ageing (ELSA) cohort. ELSA is a longitudinal study of middle-aged and older adults living in England. Data were taken from three consecutive waves. Demographics, BMI, and self-reported pain were collected at wave 4 (2008–2009), perceived weight discrimination at wave 5 (2010–2011,) and pain (no/mild vs moderate/severe) at wave 6 (2012–2013). Generalized linear models estimated the association of BMI at wave 4 (assessed continuously and dichotomized to obesity status BMI ≥30) with pain at wave 6, and weight discrimination at wave 5 as a mediator of this relationship. Models were adjusted for demographics and baseline pain. Complete data were available for n=5362 individuals. Continuous BMI was associated with future moderate/severe pain (<em>b</em>=1.05 SE=0.01, <em>p</em><.01) and weight discrimination partially mediated this effect (<em>b</em>=1.00 SE=0.002, <em>p</em>=.05). Obesity status was also significant (b=1.43 SE=0.11, <em>p</em><.01) but weight discrimination did not mediate the relationship (<em>p</em>=.13). Post hoc analyses were conducted among individuals with no/mild pain at baseline (n=3979.) BMI and obesity status were both associated with pain and weight discrimination mediated both pathways (<em>p</em>s<.05.) Weight discrimination partially mediated the relationship between BMI and future moderate/severe pain, especially among individuals with no/mild pain initially. Weight discrimination may be an overlooked contributor to the transition to more severe pain among individuals of higher body weight.</div></div><div><h3>Perspective</h3><div>Weight discrimination may be an overlooked contributor to pain among individuals of higher body weight, particularly transition from lower to higher impact states. Post hoc analyses indicate the effect may be specific, as other forms of discrimination did not mediate the relationship.</div></div>","PeriodicalId":51095,"journal":{"name":"Journal of Pain","volume":"28 ","pages":"Article 104772"},"PeriodicalIF":4.0,"publicationDate":"2024-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142907914","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Journal of PainPub Date : 2024-12-27DOI: 10.1016/j.jpain.2024.104763
Joel N. Fishbein , Anne Malaktaris , Niloofar Afari , Matthew S. Herbert
{"title":"Multisite pain among United States Veterans with posttraumatic stress disorder: Prevalence, predictors, and associations with symptom clusters","authors":"Joel N. Fishbein , Anne Malaktaris , Niloofar Afari , Matthew S. Herbert","doi":"10.1016/j.jpain.2024.104763","DOIUrl":"10.1016/j.jpain.2024.104763","url":null,"abstract":"<div><div>Persistent pain in multiple distinct body sites is associated with poorer functional outcomes above and beyond pain intensity and interference. Veterans, and especially those with posttraumatic stress disorder (PTSD), may be at risk for multisite pain. However, the research to date characterizing this presentation is limited. This secondary analysis examined the prevalence of multisite pain in a cross-sectional sample of Veterans and explored demographic, military service-related, and PTSD symptom cluster variables associated with multisite pain among those with clinically significant PTSD symptoms. Participants were 4303 post-9/11 U.S. Veterans (16.55% female gender, 58.45% White/Caucasian, M<sub>age</sub> = 35.52), of whom 1375 (31.95%) had clinically significant PTSD symptoms. Multisite pain was defined as endorsing pain that “bothered [me] a lot” in ≥3 body sites out of 5 on the Patient Healthcare Questionnaire-15. A total of 20.03% of all participants, and 40.00% of those with likely PTSD, reported multisite pain. Female gender (OR = 1.55), older age (OR = 1.70), minority race identification (White/Caucasian racial identity OR = 0.75), history of military sexual trauma (OR = 1.99), and spine, abdomen and joint/muscle injuries (ORs = 1.66–3.68) were associated with higher odds of multisite pain. Adjusting for these potential confounders, higher <em>z-</em>scores on the PTSD arousal/reactivity (OR = 1.58, <em>p</em> <.001) subscale was associated with higher multisite pain odds. In summary, multisite pain was common among Veterans with PTSD, especially those who experienced military sexual trauma or certain physical injuries. Multisite pain and PTSD may be associated due to a shared threat reactivity mechanism.</div></div><div><h3>Perspective</h3><div>This study investigates the rates and factors associated with having pain in three or more distinct body sites (<em>multisite pain</em>) among United States Veterans. The study findings highlight the unique importance of specific posttraumatic stress symptoms and experiences associated with multisite pain.</div></div>","PeriodicalId":51095,"journal":{"name":"Journal of Pain","volume":"28 ","pages":"Article 104763"},"PeriodicalIF":4.0,"publicationDate":"2024-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142903998","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Journal of PainPub Date : 2024-12-25DOI: 10.1016/j.jpain.2024.104760
Cheryl Davies, Hemakumar Devan, Susan Reid, Jaquille Haribhai-Thompson, Dagmar Hempel, Isobel Joy Te Aho-White, Lisa Te Morenga
{"title":"\"When you're in pain you do go into your shell\" A community-based pain management programme co-designed with Māori whānau to address inequities to pain management - A qualitative case study.","authors":"Cheryl Davies, Hemakumar Devan, Susan Reid, Jaquille Haribhai-Thompson, Dagmar Hempel, Isobel Joy Te Aho-White, Lisa Te Morenga","doi":"10.1016/j.jpain.2024.104760","DOIUrl":"10.1016/j.jpain.2024.104760","url":null,"abstract":"<p><p>Chronic or persistent non-cancer pain disproportionately affects Māori - the Indigenous population of Aotearoa New Zealand (NZ) and their whānau (family and significant others). In a previous study with a Māori community service provider - Tū Kotahi Māori Asthma and Research Trust - Tū Kotahi, identified a need for a Kaupapa Māori (by Māori, for Māori) pain management programme (PMP) with embedded principles of Whānau Ora (care focusing on the wellbeing of the individual and their significant others as a collective). Using a qualitative case-study design, the main aims were to describe (1) the implementation of a community-based, whānau-focused PMP; (2) the participant experiences of the programme. This is community-based participatory action research guided by a Māori-centred research approach. Based on our previous co-design study with Tū Kotahi, a 6-week PMP (July - August 2021) was implemented at Kokiri Marae (community meeting place). Eight whānau living with persistent pain participated in the 6 sessions led by our Māori community partner and a pain management physiotherapist including a dedicated session on Rongoā Māori (Māori traditional treatment). Supporting resources were co-developed with our community partner, pain service clinicians, a Māori Health literacy expert, and a Māori illustrator. On completion, whānau reported enhanced confidence towards managing pain with \"more tools to manage\". The role of meaningful relationships, co-design, use of metaphors, and inclusion of traditional treatments - Rongoā were key aspects for the successful implementation. This initiative provides an exemplar for community and mainstream pain service partnership to address inequities in accessing pain management services for Māori. PERSPECTIVE: This study explains the key cultural processes of implementing a community-based pain management programme for Māori with persistent pain in Aotearoa New Zealand. The principles from our engagement could be applicable globally to engage with Indigenous and culturally and linguistically diverse communities with persistent pain to address longstanding health inequities.</p>","PeriodicalId":51095,"journal":{"name":"Journal of Pain","volume":" ","pages":"104760"},"PeriodicalIF":4.0,"publicationDate":"2024-12-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142900227","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}