Journal of Pain最新文献

{"title":"Widespread and prolonged pain may reduce brain clearance capacity only via sleep impairment: Evidence from participants with knee pain","authors":"Pedro A. Valdes-Hernandez ,&nbsp;Soamy Montesino-Goicolea ,&nbsp;Chavier Laffitte Nodarse ,&nbsp;Alisa J. Johnson ,&nbsp;Roger B. Fillingim ,&nbsp;Yenisel Cruz-Almeida","doi":"10.1016/j.jpain.2025.105356","DOIUrl":"10.1016/j.jpain.2025.105356","url":null,"abstract":"<div><div>The brain is key in the pain-sleep relationship, and sleep is needed for glymphatic clearance. However, no studies have examined how pain relates to the glymphatic system (GS). Characterizing the GS alongside sleep quality in well-characterized pain samples is essential for advancing this understanding. Non-invasive MRI techniques, such as Diffusion Tensor Imaging-Analysis aLong the Perivascular Space (DTI-ALPS), are particularly valuable as they are approved for humans. Although the relationship between the DTI-ALPS index and the GS is primarily deductive, the index may be a proxy for waste clearance capacity in deep white matter. Its sensitivity to interstitial space changes—known to be modulated by norepinephrine—offers a unique opportunity to investigate how sleep impairment and chronic pain regulation affect specific components of brain waste clearance. We thus fitted two longitudinal models linking pain, sleep quality and the DTI-ALPS index. We hypothesized that variations in pain characteristics would predict DTI-ALPS index changes, either directly or mediated by sleep quality changes. Alternatively, we hypothesized that variations in sleep quality would predict changes in pain characteristics via DTI-ALPS index modifications. Knee pain participants (n=87) completed an MRI and self-reported measures of pain and sleep impairment at baseline and two years later. We only found evidence supporting that more widespread and longer pain at baseline significantly influenced decreases in the DTI-ALPS index in the left hemisphere through increased sleep impairment two years later (p=0.039, corrected).</div></div><div><h3>Perspective</h3><div>Findings highlight the need for research on the relationship between pain and sleep quality and its implications for brain health.</div></div>","PeriodicalId":51095,"journal":{"name":"Journal of Pain","volume":"30 ","pages":"Article 105356"},"PeriodicalIF":4.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143544309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Language errors in pain medicine: An umbrella review","authors":"Bastien Léo Béraud ,&nbsp;André Meichtry ,&nbsp;Kay-Uwe Hanusch ,&nbsp;Roger Hilfiker","doi":"10.1016/j.jpain.2024.104738","DOIUrl":"10.1016/j.jpain.2024.104738","url":null,"abstract":"<div><div>Errors in language are common in pain medicine, but the extent of such errors has not been systematically measured. This pre-registered umbrella review explored Embase, PubMed, Medline and CINAHL and seeks to quantify the prevalence of errors in language in review articles since the last IASP definition revision. To be eligible, studies must have met the following criteria: 1) Primary aim was stated as to provide neurophysiological explanations of nociception and/or pain in humans in context of a pathology/condition; 2) Any type of review article; 3) Written in English; 4) Published in a peer-reviewed journal. Studies were excluded if they met any of the following criteria: 5) Published prior to the last revision of the IASP definition; 6) Published after May 2023; 7) Published in a predatory journal. Out of 5470 articles screened, 48 review articles met the inclusion criteria. All articles contained at least one error in language, there were no differences in the proportions of errors in language in review articles between years of publication, and various predictors were mostly not associated with a higher or lower number of errors in language counts in articles. Our findings reveal the need for heightened awareness among researchers, clinicians, journals and editorial boards regarding the prevalence and impact of these errors. Given our findings and their limitations, further research should focus on examining the contextual influence of misnomer usage and replication of these results.</div></div><div><h3>Perspective</h3><div>This umbrella review explored the main biomedical databases to see how many review articles contained language errors. Our findings underscore the imperative for prompt action in regulating pain medicine terminology.</div></div><div><h3>Pre-registration</h3><div>This umbrella review was pre-registered on OSF registries (https://doi.org/10.17605/osf.io/kau8m).</div></div><div><h3>Online material</h3><div><span><span>https://osf.io/kdweg</span><svg><path></path></svg></span>/</div></div>","PeriodicalId":51095,"journal":{"name":"Journal of Pain","volume":"28 ","pages":"Article 104738"},"PeriodicalIF":4.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142693884","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Erratum to TRPA1 agonist-responsive afferents contribute to central sensitization by suppressing spinal GABAergic interneurons through somatostatin 2A receptors [J Pain 25 12 (2024) 104686]","authors":"Ramesh Pariyar,&nbsp;Jigong Wang,&nbsp;Regan Hammond,&nbsp;Ho Koo,&nbsp;Nicholas Dalley,&nbsp;Jun-Ho La","doi":"10.1016/j.jpain.2025.105355","DOIUrl":"10.1016/j.jpain.2025.105355","url":null,"abstract":"","PeriodicalId":51095,"journal":{"name":"Journal of Pain","volume":"29 ","pages":"Article 105355"},"PeriodicalIF":4.0,"publicationDate":"2025-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143508520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of acceptance and commitment therapy plus exercise for older adults with chronic low back pain: A preliminary cluster randomized controlled trial with qualitative interviews","authors":"Jae Q.J. Liu ,&nbsp;Yim Wah Mak ,&nbsp;Aled L.Y. Tang ,&nbsp;Crystal Kwan ,&nbsp;Fadi Al Zoubi ,&nbsp;Timmy K.T. Wong ,&nbsp;Gordon S.H. Tsang ,&nbsp;Heidi C.W. Kwong ,&nbsp;Sabrina W.T. Lai ,&nbsp;Sam P.S. Sze ,&nbsp;Kelvin T.K. Hui ,&nbsp;Chelsia K.C. Cheung ,&nbsp;Dino Samartzis ,&nbsp;Karen K.S. Chow ,&nbsp;Arnold Y.L. Wong","doi":"10.1016/j.jpain.2025.105350","DOIUrl":"10.1016/j.jpain.2025.105350","url":null,"abstract":"<div><div>Chronic low back pain (CLBP) is increasingly prevalent in older adults and often leads to functional disability and depressive symptoms. This 2-arm, double-blinded, pilot cluster RCT, with semi-structured interviews, aimed to evaluate the acceptability, feasibility, and preliminary clinical efficacy of ACT plus exercise training (ACT+Ex) on improving pain-related outcomes, psychological outcomes, and physical fitness in older adults with CLBP at post-treatment and 6-month follow-up. Forty community-dwelling older adults (62–85 years) with CLBP, predominantly female, were randomized to ACT+Ex (n=20) or Education plus exercise program (Edu+Ex) (n=20) for 8 weekly group-based sessions, with assessments at baseline, post-treatment, and 6-month follow-up (primary endpoint). Self-reported outcomes included pain intensity, functional disability (Roland Morris Disability Questionnaires, RMDQ), health-related quality of life (EuroQol-5 Dimensions, EQ-5D-5L), psychological inflexibility (Acceptance and Action Questionnaire-Version 2, AAQ-II), and psychological well-being (Depression Anxiety Stress Scale). Physical fitness was assessed using the functional reach test (FRT), Timed Up and Go test (TUG), 6-minute walk test (6MWT), hand grip strength (HGS), and 30-second sit-to-stand (STS-30) test. This trial achieved high recruitment (23.5 participants per week) and completion rates (92.5%). Exploratory analyses revealed that ACT+Ex significantly improved pain intensity, disability, psychological inflexibility, HRQoL, and physical fitness at post-treatment and 6-month follow-up. Qualitative data identified 3 superordinate themes: previous healthcare experience affecting pain beliefs; acceptance strategies guiding behavioral changes; and facilitators and barriers to treatment compliance. These findings support the need for a definitive RCT and form a valuable basis for future exploration regarding the behavioral mechanisms of ACT in clinical applications.</div></div><div><h3>Perspective</h3><div>A multimodal therapy incorporating ACT and exercise promotes positive behavioral changes and its treatment effects are maintained at the 6-month follow-up especially for physical performance.</div></div>","PeriodicalId":51095,"journal":{"name":"Journal of Pain","volume":"30 ","pages":"Article 105350"},"PeriodicalIF":4.0,"publicationDate":"2025-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143532189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Identifying comorbid obstructive sleep apnea in chronic musculoskeletal pain: A systematic review.","authors":"Julya Perea, Julia Kortstee, Zosia Goossens, Nils Runge, Céline Labie, Jo Nijs, Liesbet De Baets","doi":"10.1016/j.jpain.2025.105351","DOIUrl":"10.1016/j.jpain.2025.105351","url":null,"abstract":"<p><p>Obstructive sleep apnea (OSA) is common in patients with chronic musculoskeletal pain (CMP). Understanding the characteristics of the CMP population with comorbid OSA is important for proper screening and management. This systematic review compiles evidence on methods used to identify OSA in patients with CMP and identifies the characteristic features of patients with CMP and comorbid OSA. A systematic search was conducted in Medline (PubMed), Embase and Web of Science. Broad search terms related to sleep apnea and CMP were used. Studies had to include individuals with CMP diagnosed with OSA or individuals with CMP in whom OSA symptoms were assessed as outcomes. The protocol was pre-registered on PROSPERO (CRD42024516140). The initial search identified 3832 records, and 30 studies (total n=7085 participants) were included. Laboratory sleep polysomnography was the most used objective assessment method, while the Berlin and STOP-BANG questionnaires were the most used self-report instruments. However, these questionnaires showed poor agreement with polysomnography. The results consistently showed that fatigue and pain distribution did not differ between CMP patients with and without OSA. Inconsistent results were found regarding higher age, higher body mass index, psychological factors, decreased sleep quality, increased sleepiness, and pain intensity as characteristic features of the CMP with OSA population compared to the CMP without OSA. No factors consistently characterized the CMP with OSA population. Further research is required to explore the factors that consistently characterize patients with CMP with comorbid OSA to improve the effectiveness of screening for OSA in daily practice. PERSPECTIVE: This work summarizes the tools used to assess obstructive sleep apnea in populations with chronic musculoskeletal pain and highlights the features of individuals with both conditions compared to those with only chronic musculoskeletal pain.</p>","PeriodicalId":51095,"journal":{"name":"Journal of Pain","volume":" ","pages":"105351"},"PeriodicalIF":4.0,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143525130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A malevolent force: A qualitative exploration of perceptions of changes in bodily function and sensations in complex regional pain syndrome","authors":"Holly Waring ,&nbsp;Abigail F. Jones ,&nbsp;Antonia F. Ten Brink ,&nbsp;Andreas Goebel ,&nbsp;Candy McCabe ,&nbsp;Janet H. Bultitude ,&nbsp;Abbie Jordan","doi":"10.1016/j.jpain.2025.105354","DOIUrl":"10.1016/j.jpain.2025.105354","url":null,"abstract":"<div><div>Research has established that people with complex regional pain syndrome (CRPS) experience profound changes in bodily function and sensations. However, the subjective perceptions of these changes to bodily function and sensations have not yet been explored. The current investigation aimed to qualitatively explore perceptions of changes in bodily function and sensations for people living with CRPS. The study comprised a secondary analysis of qualitative responses obtained from 288 people with CRPS from an online worldwide survey. Responses to two open-ended questions regarding the experience of changes in bodily function and sensations were analysed using qualitative content analysis. Two themes were generated, “<em>An act of evil</em>” and “<em>Becoming sub-human</em>”. Changes in bodily function and sensations were perceived by participants as a malevolent force, described by participants as volatile and hostile in nature. Furthermore, participants felt they had become sub-human due to the loss of autonomy, social exclusion, and the inability for their body to work ‘as it should.’ Future research should undertake a longitudinal examination of the experience of changes in bodily function and sensations associated with living with CRPS to fully understand the long-term impact of such changes on the individual and their quality of life.</div></div><div><h3>Perspective</h3><div>The impacts of changes in bodily function and sensations for people living with CRPS are profound, with participants describing them as a malevolent force which robs them of their humanity.</div></div>","PeriodicalId":51095,"journal":{"name":"Journal of Pain","volume":"29 ","pages":"Article 105354"},"PeriodicalIF":4.0,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143519127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Neural response associated with the modulation of temporal summation of second pain by affective touch","authors":"Elley Wakui ,&nbsp;Fabrizia Fidanza ,&nbsp;Matteo Martini","doi":"10.1016/j.jpain.2025.105349","DOIUrl":"10.1016/j.jpain.2025.105349","url":null,"abstract":"<div><div>Temporal summation of second pain (TSSP) is a phenomenon that has clinical relevance but insights into its functioning are limited. Lately, ‘affective touch’ (AT) has been shown to have pain relieving properties but only one study has investigated its effects on TSSP and the neural underpinnings of such interaction are unknown. In the present EEG study, thirty-six healthy participants went through three conditions where a TSSP protocol was applied in concomitance with no touch (NoT), discriminative touch (DT) and AT. A fourth no-pain no-touch condition acted as a baseline. Measures of attention during the four conditions and of pleasantness during the touch conditions were also recorded. Pain ratings were significantly lower only during the AT condition. The neural response during NoT, compared to the baseline, brought about a temporal decrease in power at delta and theta frequencies and a fronto-central increase mainly in the alpha rhythm. Adding AT to TSSP yielded, compared to NoT, a decrease in delta, theta and beta bands in midline regions at both central (Cz) and parietal (Pz) and also of gamma at Pz. Notably, DT was not associated with significant changes compared to pain alone (NoT), but a specific marked difference was found between AT and DT with the former showing a significant decrease in beta frequencies localized at Pz. While TSSP seems to be characterized by a modulation mostly of the lower frequencies, adding AT to TSSP brings a clear depression of all the major frequency bands. Additionally, the parietal beta reduction may be a biomarker of AT. Future studies can examine if such brain response can help finding a suitable intervention for TSSP-related chronic pain conditions.</div></div><div><h3>Perspective</h3><div>This study consolidates the idea that AT can lower pain in a TSSP paradigm and shows what are the brain (EEG) responses associated with both TSSP and TSSP modulation by AT. Given that TSSP is linked to central sensitization and that it can be used as an experimental model for chronic pain, our results pave the way for further studies into the neural mechanisms of AT-led analgesia, which can lead to future effective treatments.</div></div>","PeriodicalId":51095,"journal":{"name":"Journal of Pain","volume":"29 ","pages":"Article 105349"},"PeriodicalIF":4.0,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143525132","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence of low back pain in Nepal: Results from a nationally representative WHO STEPS survey","authors":"Sweekriti Sharma ,&nbsp;Adrian C. Traeger ,&nbsp;Chris G. Maher ,&nbsp;Bihungum Bista ,&nbsp;Meghnath Dhimal ,&nbsp;Lonim P. Dixit ,&nbsp;Saurab Sharma","doi":"10.1016/j.jpain.2025.105352","DOIUrl":"10.1016/j.jpain.2025.105352","url":null,"abstract":"<div><div>Low back pain is the leading cause of disability globally. Most prevalence data for low back pain come from high-income countries. Data from low-and middle-income countries such as Nepal are currently lacking. This study aimed to estimate one-month prevalence of low back pain in Nepal using a nationally representative sample and present the prevalence estimates by socio-demographic characteristics. We used national population-based survey data from the World Health Organisation (WHO) STEPwise Approach to Non-communicable Disease Risk Factor Surveillance (STEPS) survey conducted in Nepal from February to May 2019 with people aged 15 to 69 years. We reported the age-standardised low back pain prevalence (95% CI). We used univariate and multivariable logistic regression to assess the associations between sociodemographic variables and the presence of low back pain and results were presented as odds ratios. A total of 5593 people aged 15 to 69 years participated in the survey. The response rate was 86.4%. The age-standardised prevalence of activity limiting low back pain was 23.2% (95% CI: 21.9% to 24.5%). Older people were more likely to have low back pain than younger people. For example, people aged 55–69 years had over 4 times higher odds of having low back pain than people aged 15–24 years [odds ratio: 4.06 (95%CI= 2.57 to 6.42)]. Females had 1.74 times higher odds of having low back pain than males [odds ratio: 1.74 (95%CI= 1.45 to 2.09)]. The results of our study show that a quarter of adults are affected by low back pain in Nepal; with women and older people more likely to experience low back pain.</div></div><div><h3>Perspective</h3><div>This study shows that a quarter of adults are affected by low back pain in Nepal. Women and older people are more likely to experience back pain in Nepal.</div></div>","PeriodicalId":51095,"journal":{"name":"Journal of Pain","volume":"30 ","pages":"Article 105352"},"PeriodicalIF":4.0,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143517418","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Equity Using Interventions for Pain and Depression (EQUIPD): A pilot randomized trial","authors":"Marianne S. Matthias Ph.D. ,&nbsp;Diana J. Burgess Ph.D. ,&nbsp;Joanne K. Daggy Ph.D. ,&nbsp;Claire E. Donnelly M.A. ,&nbsp;Perla Flores B.S. ,&nbsp;Nicole R. Fowler Ph.D., M.H.S.A. ,&nbsp;Jennifer Garabrant B.S.W. ,&nbsp;Nancy Henry B.A. ,&nbsp;Stephen G. Henry M.D. ,&nbsp;Monica Huffman B.S. ,&nbsp;Pavani Jyothi Kavuri M.S. ,&nbsp;Susan Ofner M.S. ,&nbsp;Canaan Perry B.S. ,&nbsp;Kevin L. Rand Ph.D. ,&nbsp;Maria Robles M.D. ,&nbsp;Michelle P. Salyers Ph.D. ,&nbsp;Stephanie L. Taylor Ph.D. ,&nbsp;Adam T. Hirsh Ph.D.","doi":"10.1016/j.jpain.2025.105353","DOIUrl":"10.1016/j.jpain.2025.105353","url":null,"abstract":"<div><div>Despite increased calls for improved health equity, Black patients continue to experience worse pain and associated outcomes. Black patients are also offered fewer pain treatment options than White patients and report poorer quality communication with clinicians, including lower participation in shared decision-making. Comorbid depressive symptoms can impede effective pain management and participation in decision-making. The Equity Using Interventions for Pain and Depression (EQUIPD; NCT05695209) pilot study examined feasibility of a one-on-one coaching intervention, paired with a decision aid, to facilitate shared decision-making about evidence-based nonpharmacological pain treatments for Black patients with chronic musculoskeletal pain and symptoms of at least mild depression. We recruited and randomized 30 participants at a rate of 7.5 per month, with 90% retention at 3 months and 87% at 6 months. Intervention participation was high, with 94% of participants completing at least 3 of 4 coaching sessions. Fidelity was also high. Although not powered for effectiveness, most outcomes, including pain interference, depression, anxiety, patient engagement, and shared decision-making, improved, favoring the intervention, with effect sizes ranging from 0.30–0.75 at 3 months. Results indicate that EQUIPD holds promise as an intervention to support autonomy and shared decision-making for Black patients with chronic pain and elevated depressive symptoms.</div></div><div><h3>Perspective</h3><div>The EQUIPD intervention, which included one-on-one coaching combined with a decision aid to increase shared decision-making about nonpharmacological pain treatments, was feasible and shows promise in improving pain and related outcomes for Black patients with chronic musculoskeletal pain and depressive symptoms.</div></div>","PeriodicalId":51095,"journal":{"name":"Journal of Pain","volume":"29 ","pages":"Article 105353"},"PeriodicalIF":4.0,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143517417","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corrigendum to “Hyperbaric oxygen attenuates chronic postsurgical pain by regulating the CD73/adenosine/A1R axis of the spinal cord in rats” [J Pain 25, 2024, 104623]","authors":"Lijun Yin ,&nbsp;Wenwu Liu ,&nbsp;Zhe Zhang ,&nbsp;Jingyue Zhang ,&nbsp;Hui Chen ,&nbsp;Lize Xiong","doi":"10.1016/j.jpain.2025.105325","DOIUrl":"10.1016/j.jpain.2025.105325","url":null,"abstract":"","PeriodicalId":51095,"journal":{"name":"Journal of Pain","volume":"28 ","pages":"Article 105325"},"PeriodicalIF":4.0,"publicationDate":"2025-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143429489","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}