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Evaluating the Use of Vitamin D Supplementation to Improve Glycaemic Outcome in Type 2 Diabetes Mellitus Patients: A Systematic Review of Evidence 评价补充维生素D对改善2型糖尿病患者血糖结局的作用:证据的系统回顾
IF 2.6 4区 计算机科学
Journal of Database Management Pub Date : 2017-09-21 DOI: 10.4236/JDM.2017.74018
M. Mabhala, Adetoyosi Babanumi, A. Olagunju, Eloho Akata, Asmait Yohannes
{"title":"Evaluating the Use of Vitamin D Supplementation to Improve Glycaemic Outcome in Type 2 Diabetes Mellitus Patients: A Systematic Review of Evidence","authors":"M. Mabhala, Adetoyosi Babanumi, A. Olagunju, Eloho Akata, Asmait Yohannes","doi":"10.4236/JDM.2017.74018","DOIUrl":"https://doi.org/10.4236/JDM.2017.74018","url":null,"abstract":"Background: The evidence indicates that vitamin D [25(OH)D] improves glycaemic \u0000outcomes in type 2 Diabetes mellitus patients. The outcome measures used to \u0000determine the accuracy of this hypothesis are: glycosylated hemoglobin (HbA1c), \u0000fasting plasma glucose (FPG) and homeostasis model assessment-insulin resistance \u0000(HOMA-IR). Methods: We performed a systematic review and meta-analysis \u0000which included all previous randomised controlled trial (RCT) studies that \u0000assessed the effects of vitamin D on glucose metabolism. We carried out an \u0000extensive electronic database search of published and unpublished RCTs, \u0000evaluating the association between vitamin D and glycaemic outcomes in type 2 \u0000diabetes mellitus patients. We searched Cochrane Library, PubMed, EMBASE, \u0000CINAHL Plus with Full Text, MEDLINE, BioMed Central, Turning Research Into \u0000Practice (TRIP), Health Technology Assessment (HTA), and Latin American and \u0000Caribbean Health Sciences (LILIACS) between the years 2005 and 2016. The full \u0000texts of relevant studies were retrieved and a snowballing technique was used \u0000to discover further studies missed from the initial database search. This was \u0000done by hand-searching for references within the retrieved articles. Results: A total of 17 studies were included in the review. The pooled effect of 15 \u0000studies that measured HbA1c showed an insignificant effect of vitamin D on \u0000HbA1c (Mean difference (MD) = -0.06 mmol/l; 95% CI = -0.26 to 0.14; I2 = 76%). A pooled analysis of seven studies \u0000that measured the effect of vitamin D on blood glucose also found no \u0000significant effect of vitamin D on T2DM (MD = -0.03 mmol/l; \u000095% CI = -0.69 to 0.63; I2 = 76%). Three \u0000studies that analysed the effect of vitamin D on insulin sensitivity also \u0000observed no significant effect (MD = -1.51 mmol/l; 95% CI = -3.61 \u0000to 0.60; I2 = 67%). Conclusion: In conclusion, although \u0000vitamin D has been extensively studied in relation to some glycaemic outcomes \u0000and some indications that increased plasma vitamin D concentrations might be \u0000linked to prevention of T2DM, firm universal conclusions about its benefits \u0000cannot be drawn. Further studies with better designed trials and larger sample \u0000sizes are needed to draw firmer conclusions.","PeriodicalId":51086,"journal":{"name":"Journal of Database Management","volume":"07 1","pages":"223-240"},"PeriodicalIF":2.6,"publicationDate":"2017-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41407437","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"计算机科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effectiveness of Alkali Water Consumption to Reduce Blood Sugar Levels in Diabetes Mellitus Type 2 碱水对降低2型糖尿病患者血糖水平的效果
IF 2.6 4区 计算机科学
Journal of Database Management Pub Date : 2017-09-21 DOI: 10.4236/JDM.2017.74020
Edy Siswantoro, Nasrul Hadi Purwanto, Sutomo
{"title":"Effectiveness of Alkali Water Consumption to Reduce Blood Sugar Levels in Diabetes Mellitus Type 2","authors":"Edy Siswantoro, Nasrul Hadi Purwanto, Sutomo","doi":"10.4236/JDM.2017.74020","DOIUrl":"https://doi.org/10.4236/JDM.2017.74020","url":null,"abstract":"Background: Non-Communicable Diseases (NCDs) have become a public health problem, globally, regionally, nationally and locally. Non-Communicable Diseases (NCDs) that took a lot of attention was diabetes mellitus. In Indonesia diabetes mellitus is a serious threat to health development. Efforts developed to overcome the problems of diabetes mellitus type 2 is to apply four pillars of therapy namely education, nutrition therapy, physical activity and pharmacology. However, these efforts have not been able to achieve optimal results due to many obstacles encountered. One of the non-pharmacological treatments that can be utilized is to consume alkaline water to reduce blood sugar levels in diabetes mellitus type 2. Methods: The research design used was quasy experiment with pre-post control group design approach. The variables observed in this study were random blood sugar changes in people with diabetes mellitus type 2 prior to intervention and after intervention. Intervention is given over a period of 14 days. To measure the demand of drinking water on the respondents, the measurement was done using Water Drink Reminder - Hydro application. The alkaline water used in this study is alkaline water produced from Kangen Water Type SD501 Platinum Machine. Test analysis used is paired t test to determine the effectiveness of alkaline water consumption to decrease random blood sugar level of diabetes mellitus type 2. To know the difference of effectiveness of alkaline water consumption to decrease of blood sugar level, it uses one way anova test with significance value α: 0.05. Results: From result of the one way anova test with significance value α: 0.05, we have got significance 0.039. Since the significance probability value is 0.039 < 0.05, the research hypothesis is accepted which means that there is a significant difference in the level of random blood sugar of diabetes mellitus type 2 performed by using four kinds of intervention of alkaline water treatment (Alkali Water PH 7.0, PH 8.0, PH 9.5 and PH 9.5 and PH 11.5) for a period of 14 days. Conclusion: Support from health personnel and adherence to diabetes mellitus is required to utilize alkaline water as nonpharmacologic therapy to control blood sugar levels in people with type 2 diabetes mellitus. To achieve maximum results from nonfarmakologi therapy performed, people with diabetes mellitus type 2 should routinely consume antidiabetic drugs provided by health personnel and always strive for a healthy life.","PeriodicalId":51086,"journal":{"name":"Journal of Database Management","volume":"07 1","pages":"249-264"},"PeriodicalIF":2.6,"publicationDate":"2017-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45238815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"计算机科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
PENGOLAHAN SAYUR BAYAM MENJADI ES KRIM: PENGEMBANGAN KREATIVITAS MASYARAKAT DESA 犯罪:英国创造力的发展
IF 2.6 4区 计算机科学
Journal of Database Management Pub Date : 2017-09-13 DOI: 10.31850/jdm.v1i1.241
Antong Antong, Astrina Maharani
{"title":"PENGOLAHAN SAYUR BAYAM MENJADI ES KRIM: PENGEMBANGAN KREATIVITAS MASYARAKAT DESA","authors":"Antong Antong, Astrina Maharani","doi":"10.31850/jdm.v1i1.241","DOIUrl":"https://doi.org/10.31850/jdm.v1i1.241","url":null,"abstract":"Tujuan program ini adalah mengolah sayur bayam menjadi es krim sekaligus membina petani sayur bayam dan masyarakat agar lebih inovatif dan kreatif dalam memberikan nilai tambah hasil pertanian mereka yang melimpah dan mudah didapatkan sehingga lebih berdaya guna dan bernilai ekonomis. Pembuatan es krim sebenarnya sederhana saja, yakni mencampurkan bahan-bahan dan kemudian mendinginkan. Es krim yang biasanya terdapat di pasaran biasanya terbuat atau berbahan dasar susu cair. Metode yang digunakan dalam program ini yakni dengan melakukan penyuluhan sekaligus pelatihan kepada masyarakat setempat tentang pengolahan sayur bayam menjadi sebuah produk yang lebih menarik dan berniali ekonomis yaitu es krim bayam yang selanjutnya akan dipasarkan oleh BUMDes sebagai lembaga bisnis kolaborasi pemerintah desa dan masyarakat. Kegiatan ini dilakukan dengan dukungan dari pemerintah setempat serta mahasiswa STIE Muhammadiyah Palopo. Selain itu masyarakat Desa Burau, Kecamatan Burau khususnya para petani serta kelompok kelompok masyarakat sekitarnya diberdayakan dalam kegiatan ini. Hingga saat ini program pelatihan kepada masyarakat mengenai pembuatan es krim bayam telah dilakukan, selain itu pengetahuan mengenai pemasaran dan perhitungan harga pokok juga diberikan kepada masyarakat. Monitoring terhadap kegiatan masih akan terus dilakukan sebagai rencana tahapan selanjutnya.","PeriodicalId":51086,"journal":{"name":"Journal of Database Management","volume":"1 1","pages":"42-51"},"PeriodicalIF":2.6,"publicationDate":"2017-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45850264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"计算机科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
INOVASI KEAKSARAAN UNTUK PEMBERDAYAAN DAN PEMBERANTASAN BUTA AKSARA DI KABUPATEN ENREKANG 转让与发展准入的创新与世界准入
IF 2.6 4区 计算机科学
Journal of Database Management Pub Date : 2017-09-13 DOI: 10.31850/JDM.V1I1.221
Patahuddin Patahuddin, Syawaluddin Syawal, Arham Arham
{"title":"INOVASI KEAKSARAAN UNTUK PEMBERDAYAAN DAN PEMBERANTASAN BUTA AKSARA DI KABUPATEN ENREKANG","authors":"Patahuddin Patahuddin, Syawaluddin Syawal, Arham Arham","doi":"10.31850/JDM.V1I1.221","DOIUrl":"https://doi.org/10.31850/JDM.V1I1.221","url":null,"abstract":"P enyelenggaraan program Inovasi Keaksaraan untuk Pemberdayaan dan Pemberantasan Buta Aksara dilaksanakan untuk: a. Mencapai target percepatan penuntasan buta aksara sesuai target Inpres Nomor 5 tahun 2006, sehingga proporsi penduduk buta aksara berusia 15 tahun ke atas adalah paling banyak 5 persen. b. Meningkatkan perluasan akses pendidikan keaksaraan (tingkat dasar) bagi penduduk buta aksara usia 15 tahun ke atas melalui peningkatan pengetahuan, sikap dan keterampilan, sehingga memiliki kemampuan untuk meningkatkan kesejahteraannya. c. Memberikan penguatan keaksaraan bagi sasaran program pendidikan keaksaraan. d. Meningkatkan indeks pembangunan manusia Indonesia secara nasional, melalui peningkatan angka melek aksara penduduk di setiap kabupaten/kota. e. Meningkatkan motivasi dan komitmen pemerintah daerah untuk mendukung program pendidikan keaksaraan dengan mengembangkan inovasi keaksaraan sesuai potensi dan karakteristik daerah setempat. Hasil yang didapatkan dalam pelaksanaan program ini adalah: (1) Tercapainya target percepatan penuntasan buta aksara sesuai dengan target Inpres Nomor 5 tahun 2006 melalui dukungan perguruan tinggi dan lembaga/organisasi mitra; (2) Meningkatnya akses pelayanan program pendidikan keaksaraan bagi penduduk buta aksara usia 15 tahun ke atas khususnya bagi perempuan, sebagai upaya untuk meningkatkan pengetahuan, sikap dan keterampilan, sekaligus untuk meningkatkan kesejahteraannya; (3) Menguatnya keberaksaraan penduduk melalui penyelenggaraan program pendidikan keaksaraan; (4) Meningkatnya angka melek aksara penduduk di Kabupaten Enrekang, sehingga menyumbang peningkatan indeks pembangunan manusia Indonesia; dan (5) Meningkatnya motivasi dan komitmen lembaga/organisasi penyelenggara di Kabupaten Enrekang untuk mendukung program pendidikan keaksaraan, dan berkembangnya layanan program berupa inovasi keaksaraan sesuai potensi dan karakteristik daerah.","PeriodicalId":51086,"journal":{"name":"Journal of Database Management","volume":"1 1","pages":"14-22"},"PeriodicalIF":2.6,"publicationDate":"2017-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46170151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"计算机科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
IbM PENGUASAAN PRACTICAL ENGLISH DENGAN MEMFASILITASI “A SELF STUDY BOOK OF ENGLISH DAILY CONVERSATIONS AND WORDS” KEPADA SISWA-SISWI DI KELURAHAN LAPADDE KOTA PAREPARE IbM PENGUAN实用英语DENGAN MEMFASILITASI“英语日常会话和单词自学书”KEPADA SISWA-SISWI DI KELURATION LAPADDE KOTA PAREPARE
IF 2.6 4区 计算机科学
Journal of Database Management Pub Date : 2017-09-13 DOI: 10.31850/jdm.v1i1.228
Khadijah Maming, St. Maryam
{"title":"IbM PENGUASAAN PRACTICAL ENGLISH DENGAN MEMFASILITASI “A SELF STUDY BOOK OF ENGLISH DAILY CONVERSATIONS AND WORDS” KEPADA SISWA-SISWI DI KELURAHAN LAPADDE KOTA PAREPARE","authors":"Khadijah Maming, St. Maryam","doi":"10.31850/jdm.v1i1.228","DOIUrl":"https://doi.org/10.31850/jdm.v1i1.228","url":null,"abstract":"Peneliti berfokus pada kosakata dan kemampuan berbicara sebagai salah satu komponen bahasa yang sangat penting dan merupakan pendukung untuk menguasai skill berbahasa lainnya. Hal tersebut juga yang menjadi permasalahan bagi kedua mitra IbM, dimana siswa-siswi memiliki kemampuan yang rendah dalam hal perbendaharaan kata-kata dan kemampuan berbicara. Olehnya itu, siswa-siswi tingkat sekolah dasar sampai menengah harus dapat menguasai Practical English , dalam hal ini pengembangan kosakata dan kemampuan berbicara. Kemampuan untuk bisa fasih bercakap-cakap dalam bahasa Inggris yaitu bahwa itu perlu dilatih setiap hari. Untuk dapat aktif dan lancar dalam berbicara bahasa Inggris, pembelajar tidak boleh hanya mengandalkan buku-buku ataupun bentuk-bentuk tertulis semata. Oleh sebab itu, pembelajar harus mengetahui banyak kumpulan kosakata yang memadai dan konteks bahasa serta yang terutama penggunaannya. Peneliti memfasilitasi sebuah materi-materi dasar bahasa Inggris yang sifatnya materi tambahan berupa materi petunjuk “ Self Study Book of Daily Conversation and Words ”. Mereka difasilitasi teks-teks bacaan yang sederhana dengan judul yang bervariasi kemudian siswa-siswi diminta untuk membaca dan menterjemahkan dengan bantuan kamus bahasa Inggris serta daftar kosakata yang kemudian dihapal sekitar 10-20 kata perhari. Selian itu, disiapkan juga topik-topik percakapan beserta contoh-contoh ungkapan yang menarik serta mudah dikomunikasikan. Dengan dasar kosakata dan ungkapan bahasa Inggris yang diketahui, mereka mengaplikasikannya dalam bentuk praktek berkomunikasi. Hasil kegiatan ini siswa mampu membedakan jenis-jenis kata yaitu kata benda, kata sifat, kata kerja, kata keterangan, kata ganti diri, kata depan, dan beberapa kata tambahan ( addition ). Perbendaharaan kosakata mereka juga meningkat secara perlahan-lahan, dalam hal ini mereka mampu mengingat kata-kata Bahasa Inggris sebagaimana yang tertera pada Self Guide Book tersebut. Selanjutnya, pada aspek kemampuan berbicara, mereka sudah mampu memanfaatkan kata-kata dan kalimat-kalimat dasar yang mereka telah pahami dan hapal yang kemudian mereka gunakan dalam bercakap-cakap dan berinteraksi dengan teman-temannya. Ditambah juga aspek mental, yaitu keberanian dan kepercayaan diri mereka meningkat khusunya dalam berkomunikasi menggunakan bahasa Inggris.","PeriodicalId":51086,"journal":{"name":"Journal of Database Management","volume":"1 1","pages":"31-41"},"PeriodicalIF":2.6,"publicationDate":"2017-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49085869","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"计算机科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
MANAJEMEN PENGELOLAAN TERNAK KAMBING DI DESA BATU MILA SEBAGAI PENDAPATAN TAMBAHAN PETANI LAHAN KERING 数百万人的世界增长管理
IF 2.6 4区 计算机科学
Journal of Database Management Pub Date : 2017-09-10 DOI: 10.31850/JDM.V1I1.246
S. Suherman, Edi Kurniawan
{"title":"MANAJEMEN PENGELOLAAN TERNAK KAMBING DI DESA BATU MILA SEBAGAI PENDAPATAN TAMBAHAN PETANI LAHAN KERING","authors":"S. Suherman, Edi Kurniawan","doi":"10.31850/JDM.V1I1.246","DOIUrl":"https://doi.org/10.31850/JDM.V1I1.246","url":null,"abstract":"Pelaksanaan program kegiatan pengabdian secara umum telah memberikan hasil melalui implementasi teknologi manajemen kandang dan pengelolaan limbah ternak berupa feses. Metode yang digunakan sebagai solusi permasalahan mitra adalah dengan memberikan penyuluhan dan pelatihan. Pola manajemen kandang yang dilakukan adalah sistem panggung baterai. Di mana setiap baterai diisi satu ekor ternak. Pakan hijauan cenderung diberikan adalah daun gamal, meskipun gamal memiliki kandungan nutrisi baik, namun masih terdapat beberapa hijauan yang tersedia dan cukup baik diberikan pada ternak kambing , salah satunya adalah daun jati putih yang cukup tersedia di lokasi mitra . Untuk pengembangan usaha ternak yang lebih baik dibutuhkan setidaknya 1 ekor pejantan untuk merangsang peningkatan siklus masa birahi ternak . Pengolahan limbah ternak kambing berupa feses lebih berpotensi untuk dijadikan sumber penghasilan. Feses kambing tersedia dan tidak dimanfaatkan oleh mitra dengan baik. Penggunaan feses tanpa adanya pengolahan (fermentasi) dapat merugikan tanaman karena kandungan amoniak dan tekstur feses yang dapat berpengaruh ke tanaman.","PeriodicalId":51086,"journal":{"name":"Journal of Database Management","volume":"1 1","pages":"7-13"},"PeriodicalIF":2.6,"publicationDate":"2017-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47366364","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"计算机科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 9
Type 2 Diabetes Mellitus in Children and Adolescents: Early Prevention and Non-Drug Therapy 儿童和青少年2型糖尿病:早期预防和非药物治疗
IF 2.6 4区 计算机科学
Journal of Database Management Pub Date : 2017-07-11 DOI: 10.4236/JDM.2017.73010
Lunan Zhao, T. Long, A. Hui, R. Zhao, Shao-hua Long, Wen-hui Peng
{"title":"Type 2 Diabetes Mellitus in Children and Adolescents: Early Prevention and Non-Drug Therapy","authors":"Lunan Zhao, T. Long, A. Hui, R. Zhao, Shao-hua Long, Wen-hui Peng","doi":"10.4236/JDM.2017.73010","DOIUrl":"https://doi.org/10.4236/JDM.2017.73010","url":null,"abstract":"The global rate of type 2 diabetes mellitus (T2DM) in youth has increased dramatically in the last 30 years. This increase mirrors the global epidemic of childhood obesity. Studies show that, compared to adults who develop T2DM, youth with T2DM ultimately suffer from more harmful symptoms. The prevalence of T2DM and obesity in youth signals a significant public health issue that financially burdens governments, families, and individuals. Since evidence suggests that T2DM in youth is different from both type 1 and type 2 diabetes in adults, researchers and clinicians face many difficulties in developing new treatments. Most treatment efforts have relied on drugs; however, recent studies suggest that non-drug therapy also effectively reduces obesity and diabetic symptoms. Healthier eating, increased physical exercise, and positive mental health, are often underappreciated factors towards managing obesity. Yet these lifestyle changes empower both young and older patients to independently fight diseases and attain better health. To manage the global health risk of obesity, further research addressing the prevention and nondrug early intervention of T2DM and obesity in youth is urgently needed. The present review focuses on the latest updates in the field.","PeriodicalId":51086,"journal":{"name":"Journal of Database Management","volume":"07 1","pages":"121-141"},"PeriodicalIF":2.6,"publicationDate":"2017-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42572842","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"计算机科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 7
Association between Socio-Demographic Factors and Blood Sugar Levels in Type 2 Diabetes Mellitus Patients in Bangladesh 孟加拉国2型糖尿病患者的社会人口因素与血糖水平的关系
IF 2.6 4区 计算机科学
Journal of Database Management Pub Date : 2017-07-11 DOI: 10.4236/JDM.2017.73012
Md. Rabiul Islam
{"title":"Association between Socio-Demographic Factors and Blood Sugar Levels in Type 2 Diabetes Mellitus Patients in Bangladesh","authors":"Md. Rabiul Islam","doi":"10.4236/JDM.2017.73012","DOIUrl":"https://doi.org/10.4236/JDM.2017.73012","url":null,"abstract":"Background: The aim of the current study was to evaluate the anthropometric and demographic factors and their correlation with type 2 diabetes mellitus (T2DM) in Bangladesh. Methods: One hundred fourteen patients (70 males and 44 females) between 30 and 75 years of age from various areas of Bangladesh were screened for T2DM. Fasting blood sugar (FBS) was analyzed by using laboratory kits and spectrophotometric technique. Anthropometric and socio-demographic data were collected using a structured questionnaire. Body mass index (BMI) was calculated from weight (kg) and height (m) of the individual respondents. Physical activity was categorized based on activity during daily work. Economic condition is defined by respective family income and education level is categorized into 3 levels: illiterate, 0 - 12 years of education and graduate or above. Results: According to the current study results, half of the patients were from the middle-class family with low physical activity and their age was within the range of 30 - 45 years. The male and female ratio of the study population was 60:40. Most of the patients were found to be obese and educated. Urban populations were more prone to have DM than the rural population. Age, education, the area of residence (urban and rural), physical activity and co-morbid diseases were significantly correlated with T2DM in Bangladesh (P < 0.05). Conclusion: Our study shows that different socio-demographic factors have a significant correlation with T2DM in Bangladesh. Diabetes awareness, early diagnosis, patient education and life-style modification can be initiated to manage T2DM efficiently.","PeriodicalId":51086,"journal":{"name":"Journal of Database Management","volume":"07 1","pages":"151-159"},"PeriodicalIF":2.6,"publicationDate":"2017-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45052284","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"计算机科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 10
Efficacy and Safety of Basal-Supported Prandial GLP-1 Receptor Agonist Therapy 基础支持的Prandial GLP-1受体激动剂治疗的有效性和安全性
IF 2.6 4区 计算机科学
Journal of Database Management Pub Date : 2017-07-11 DOI: 10.4236/JDM.2017.73007
Taichi Nagahisa, M. Tabata, S. Yamada
{"title":"Efficacy and Safety of Basal-Supported Prandial GLP-1 Receptor Agonist Therapy","authors":"Taichi Nagahisa, M. Tabata, S. Yamada","doi":"10.4236/JDM.2017.73007","DOIUrl":"https://doi.org/10.4236/JDM.2017.73007","url":null,"abstract":"Aim: To assess the safety and efficacy of basal-supported prandial GLP-1 receptor agonist therapy (BPT)* in type 2 diabetes mellitus (T2DM). Methods: Patients with T2DM, who had previously received insulin injection therapy and who had had their treatment switched to BPT (liraglutide), were retrospectively recruited. The efficacy of BPT was assessed by determining changes in HbA1c, body weight and total daily insulin dose from baseline to 4 months after BPT initiation. Safety was assessed by comparing the frequency of hypoglycemic episodes at baseline and after 4 months. The Wilcoxon test was used to analyze changes in parameters throughout the study period. Results: Twenty-nine patients, previously treated with basal-supported oral therapy (BOT), basal-bolus insulin, or pre-mixed insulin, were recruited. When analyzed together, there was no change in HbA1c throughout the study period, but body weight decreased (baseline 68.8 ± 13.2 kg vs. month 4 67.3 ± 13.1 kg; p < 0.001). Total daily insulin dose decreased after 4 months (baseline 24.4 ± 15.5 U/day vs. month 4 14.7 ± 9.2 U/day; p < 0.001), and there was no change in the frequency of hypoglycemic episodes. Analysis was conducted within sub-groups based on previous treatment modality. In the BOT group, HbA1c decreased from baseline after 2 months and body weight did not change throughout the study period. In both the basal-bolus insulin group and the pre-mixed insulin group, HbA1c remained steady throughout and there was a decrease in body weight. No change in the frequency of hypoglycemia was observed in any of the sub-groups. Conclusion: BPT in T2DM was associated with weight loss without changes in glycemic control over 4 months, suggesting that it may be an effective and safe therapy.","PeriodicalId":51086,"journal":{"name":"Journal of Database Management","volume":"07 1","pages":"86-95"},"PeriodicalIF":2.6,"publicationDate":"2017-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46181703","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"计算机科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Relationship between C-Reactive Protein, White Blood Cell Count and Metabolic Syndrome in Nigerians with Type 2 Diabetes Mellitus 尼日利亚2型糖尿病患者c反应蛋白、白细胞计数与代谢综合征的关系
IF 2.6 4区 计算机科学
Journal of Database Management Pub Date : 2017-07-11 DOI: 10.4236/JDM.2017.73017
D. Soyoye, R. Ikem, B. Kolawole, R. Bolarinwa, O. Amjo, O. Yusuff, F. Owolabi, O. Ezekpo
{"title":"Relationship between C-Reactive Protein, White Blood Cell Count and Metabolic Syndrome in Nigerians with Type 2 Diabetes Mellitus","authors":"D. Soyoye, R. Ikem, B. Kolawole, R. Bolarinwa, O. Amjo, O. Yusuff, F. Owolabi, O. Ezekpo","doi":"10.4236/JDM.2017.73017","DOIUrl":"https://doi.org/10.4236/JDM.2017.73017","url":null,"abstract":"Background: Presence of metabolic syndrome (MS) in people with diabetes confers \u0000increased cardiovascular and diabetes-specific micro- and \u0000macrovascular complications. The pathogenic pathways for metabolic syndrome are \u0000still issues for discussion especially in some special groups like those with \u0000type 2 diabetes mellitus (T2DM). Recent evidences suggest that inflammation may \u0000play a key role in MS. This study assessed the relationship between MS (and its \u0000component risks) and markers of inflammation (high-sensitivity C-reactive \u0000protein {hs-CRP} and white blood cells {WBC}). Methods: A cross-sectional study involving 108 patients with T2DM. Anthropometric \u0000measurements and clinical examination were conducted. Blood sample was \u0000collected for hs-CRP, WBC, glycated haemoglobin etc. Metabolic syndrome was \u0000defined using the International Diabetes Federation criteria. Ethical approval \u0000was granted and informed consent was obtained from participants. Results: Mean age of male and female participants were 58.00 \u0000± 7.01 years and 55.48 ± 8.35 years respectively (p = 0.092). Eighty-two (75.9%) \u0000participants had metabolic syndrome. Median values of hs-CRP and total WBC were \u00000.89mg/L and 5.73 x103/mm3 respectively. On correlation, \u0000hs-CRP showed statistically significant association with waist circumference (r \u0000= 0.194; p = 0.044), fasting plasma glucose (r = 0.191; p = 0.048) and serum \u0000triglycerides (p = 0.226; r = 0.019). There was no statistically significant association between WBC and the metabolic \u0000components. Conclusion: Prevalence of metabolic syndrome is high, and C-reactive protein was associated with waist circumference, fasting plasma \u0000glucose and serum triglycerides.","PeriodicalId":51086,"journal":{"name":"Journal of Database Management","volume":"07 1","pages":"212-221"},"PeriodicalIF":2.6,"publicationDate":"2017-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41708263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"计算机科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
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