Mariel Relyea, Harsh H Buddhadev, Gordon R Chalmers, Steve Bennett
{"title":"Comparison of Balance Confidence in Older Adults With and Without Long-Haul COVID-19.","authors":"Mariel Relyea, Harsh H Buddhadev, Gordon R Chalmers, Steve Bennett","doi":"10.1123/japa.2024-0116","DOIUrl":"https://doi.org/10.1123/japa.2024-0116","url":null,"abstract":"<p><strong>Background/objectives: </strong>The effects of long COVID-19 on balance and fall risk in older adults are unknown. This study aimed to explore the relationship between balance confidence/fall risk, as assessed by the Activities-Specific Balance Confidence Scale and the Falls Efficacy Scale-International, and long COVID-19 status in older adults.</p><p><strong>Methods: </strong>This study assessed balance confidence and concern of falling in older adults (≥60 years) with long COVID-19 (long-haulers, n = 30) compared with older adults who experienced COVID-19 but not long COVID-19 (non-long-haulers, n = 60) and older adults (controls) who self-reported never having COVID-19 (n = 52). Participants gave informed consent and completed the Activities-Specific Balance Confidence Scale and the Falls Efficacy Scale-International. Data were analyzed using Kruskal-Wallis tests.</p><p><strong>Results: </strong>Long-haulers had lower balance confidence and greater concern of falling compared with non-long-haulers (p < .001; p < .001) and controls (p = .011; p = .027).</p><p><strong>Conclusion: </strong>Older adults with long-haul COVID-19 have decreased balance confidence and increased concern of falling compared with non-long-haulers and healthy controls, which may indicate a greater fall risk. Significance/Implications: Older adults with long COVID-19 may have a heightened need for resources and healthcare services related to fall prevention. Consideration of long COVID-19 status may be an important factor in improving older adult's outcomes.</p>","PeriodicalId":51073,"journal":{"name":"Journal of Aging and Physical Activity","volume":" ","pages":"1-8"},"PeriodicalIF":1.4,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143574599","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Soohyung Park, Se Hyun Park, Jieun Lee, You-Jung Choi, Dong Oh Kang, Eun Jin Park, Jah Yeon Choi, Seung-Young Roh, Dae-In Lee, Jin Oh Na, Jin Won Kim, Eung Ju Kim, Seung-Woon Rha, Chang Gyu Park, Cheol Ung Choi
{"title":"Association of Handgrip Strength With Readmission, Mortality, and Exercise Capacity in Patients With Heart Failure.","authors":"Soohyung Park, Se Hyun Park, Jieun Lee, You-Jung Choi, Dong Oh Kang, Eun Jin Park, Jah Yeon Choi, Seung-Young Roh, Dae-In Lee, Jin Oh Na, Jin Won Kim, Eung Ju Kim, Seung-Woon Rha, Chang Gyu Park, Cheol Ung Choi","doi":"10.1123/japa.2023-0298","DOIUrl":"https://doi.org/10.1123/japa.2023-0298","url":null,"abstract":"<p><strong>Background: </strong>Patients with heart failure (HF) experience a marked reduction in overall skeletal muscle strength and exercise capacity, which is detrimental to their prognosis. This study examined the clinical implications of handgrip strength (HGS) in patients with HF.</p><p><strong>Methods: </strong>Overall, 173 patients (mean age, 62 years; 81.5% male) underwent cardiac rehabilitation from 2015 to 2020. Baseline HGS was measured as the average value (kg) for both hands using a handheld dynamometer. For each patient, distance walked during a 6-min walk test and metabolic equivalents were recorded. The primary outcome was the composite of readmissions for HF and all-cause death.</p><p><strong>Results: </strong>Receiver operating characteristic curve for the primary outcome revealed 24.9 kg as the HGS cutoff point (area under curve: 0.702, 95% confidence interval [0.610, 0.794], p < .001) and multivariable Cox proportional hazard analysis revealed that lower HGS was significantly associated with a higher risk of readmission for HF or all-cause death (hazard ratio [HR] 6.44, 95% confidence interval [2.86, 14.50], p < .001). This result is mainly attributed to the increased risk of readmission for HF in this group (hazard ratio 6.75, 95% confidence interval [2.87, 15.88], p < .001). Moreover, HGS was significantly positively correlated with distance on 6-min walk test (r = .564, p < .001) and metabolic equivalents (r = .419, p < .001), and is one of the strongest predictors of each exercise capacity category.</p><p><strong>Conclusions: </strong>As our findings suggested, HGS is an indicator of exercise capacity and a useful marker for predicting hospital readmission or all-cause death in patients with HF.</p>","PeriodicalId":51073,"journal":{"name":"Journal of Aging and Physical Activity","volume":" ","pages":"1-11"},"PeriodicalIF":1.4,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143568622","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Enedina Quiroga Sánchez, María Teresa Gómez-Alonso, Natalia Arias Ramos, Arrate Pinto-Carral, María Mercedes Reguera-García, Beatriz Alonso-Cortés Fradejas
{"title":"Physical Activity Practice, Life Satisfaction, and Loneliness Among Older Adults: A Study Based on Social Network Analysis Within an Intergenerational Framework.","authors":"Enedina Quiroga Sánchez, María Teresa Gómez-Alonso, Natalia Arias Ramos, Arrate Pinto-Carral, María Mercedes Reguera-García, Beatriz Alonso-Cortés Fradejas","doi":"10.1123/japa.2024-0086","DOIUrl":"https://doi.org/10.1123/japa.2024-0086","url":null,"abstract":"<p><strong>Background/objectives: </strong>Seventy-three older adults (OAs) participated in two group physical activity programs conducted in a university-community collaboration environment. The objectives of this study were to assess changes in the amount of weekly physical activity, life satisfaction, and perceived loneliness among participants. The study aimed to analyze the relationships between these variables and establish a leadership profile.</p><p><strong>Methods: </strong>This quasiexperimental pre-post group study involved a quantitative analysis at the beginning and end of the intervention, supplemented with social network analysis methodology. Participants were assessed for weekly physical activity levels, life satisfaction, and perceived loneliness. Ethical considerations and approvals were obtained prior to the study.</p><p><strong>Results: </strong>There was a significant increase in the percentage of individuals reporting high life satisfaction. Furthermore, the level of participants experiencing severe to moderate loneliness decreased. The percentage of individuals meeting the World Health Organization's recommended weekly physical activity levels increased, along with the number of ties in social networks related to help and friendship.</p><p><strong>Conclusion: </strong>The results demonstrate the psychosocial benefits of participating in intergenerational programs focused on group physical activity within a university-community collaboration environment. The study addresses its research objectives by highlighting improvements in life satisfaction, reductions in loneliness, and enhanced social connections among OAs. Significance/Implications: These findings underscore the importance of intergenerational physical activity programs in improving the well-being of OAs. The study's outcomes have implications for practice, service delivery, policy formulation, and future research contributing to the advancement of gerontological knowledge and the improvement of outcomes for OAs.</p>","PeriodicalId":51073,"journal":{"name":"Journal of Aging and Physical Activity","volume":" ","pages":"1-7"},"PeriodicalIF":1.4,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143568698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Individual and Neighborhood Characteristics of Walking Activity in People Living With Dementia: A Proof of Concept for Quantitative Spatial Analysis.","authors":"Mohammadjavad Nouri, Habib Chaudhury","doi":"10.1123/japa.2024-0121","DOIUrl":"https://doi.org/10.1123/japa.2024-0121","url":null,"abstract":"<p><strong>Background/objectives: </strong>Creating dementia-friendly neighborhoods is crucial for enhancing outdoor walking activity and maintaining social participation among people living with dementia (PLWD). This study utilizes GPS and geographic information system technologies to conduct a quantitative spatial analysis, revealing how individual and neighborhood characteristics are associated with PLWD's walking activity characteristics.</p><p><strong>Methods: </strong>Twenty-five participants from Metro Vancouver had their regular walking routes (RWR) from home to neighborhood destinations recorded using GPS technology. Spatial analysis tools and existing survey data were utilized to construct the research geodatabase. Nonparametric tests (Spearman's rank correlation, Kendall's tau, and Mann-Whitney) and parametric tests (Pearson correlation and point biserial) assessed associations between independent variables, including sociodemographic characteristics of participants (e.g., age and health) and their neighborhoods (e.g., age structure and language barriers), and built environment features (e.g., land use diversity), with two dependent variables: length of RWR and walking time to regular destination within the 20-min walkshed.</p><p><strong>Results: </strong>Longer RWR and increased walking time to regular destination within the 20-min walkshed are associated with fewer physical health limitations, gentler terrain, proximity to green spaces, and bus stops. In addition, higher land use diversity, proximity to secondary streets, integrated sidewalks, higher number of benches and intersections, and a slight street network curvature showed positive associations with RWR length and walking time to regular destination within the 20-min walkshed.</p><p><strong>Conclusion: </strong>GPS and geographic information system technologies provide a unique quantitative method for understanding mobility patterns among PLWD. While limited by participant numbers, this exploratory study provides directions for future investigations. Significance/Implications: This study offers insights into designing dementia-friendly neighborhoods that support social engagement and physical activity among PLWD.</p>","PeriodicalId":51073,"journal":{"name":"Journal of Aging and Physical Activity","volume":" ","pages":"1-16"},"PeriodicalIF":1.4,"publicationDate":"2025-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143524890","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Gijs P G Lemmers, Susana García Juez, Aitor Carpio García, Eléonore Le Roch, Marzia Bettocchi, Paola Papini, Paolo Bellavista, Clara Gauthier, João Mota de Sousa, Guiomar Martín San Gil, Juliëtte Cruijsberg, Sergio García Batanero, Covadonga Atucha Gutiérrez, Irene Rodriguez Andonaegui, Philip J van der Wees
{"title":"The InAbled Cities Project: Development of a Physical Activity Enhancement Program for Older Adults and People With Disabilities in Spain and Italy-A Feasibility Study.","authors":"Gijs P G Lemmers, Susana García Juez, Aitor Carpio García, Eléonore Le Roch, Marzia Bettocchi, Paola Papini, Paolo Bellavista, Clara Gauthier, João Mota de Sousa, Guiomar Martín San Gil, Juliëtte Cruijsberg, Sergio García Batanero, Covadonga Atucha Gutiérrez, Irene Rodriguez Andonaegui, Philip J van der Wees","doi":"10.1123/japa.2024-0180","DOIUrl":"https://doi.org/10.1123/japa.2024-0180","url":null,"abstract":"<p><p>As life expectancies increase, people are tending toward more inactive lifestyles. Older adults and people with disabilities might benefit from accessible physical activities in nearby social networks. The purpose of this European InAbled Cities study is to develop and test the feasibility of a program aimed at enhancing physical activity for older adults and people with disabilities within their social networks. Participatory action research was conducted in two municipalities in urban (Bologna, Italy) and rural (Sevilla La Nueva, Spain) settings with older adults and people with disabilities, healthcare professionals, and communication managers. Data collection comprised a survey, interviews, and focus group interviews for developing a physical activity enhancement program, a mobile device application, and a citizen engagement strategy. Evaluation of the program's usability focused on feasibility, appropriateness, acceptability, and quality of life. The enhancement of physical activity in the two community-based settings revealed similarities and differences in the needs of citizens in the two participating municipalities. Similarities were related to behavioral change for enhancing physical activity. Differences in infrastructure were the main factors driving the need for contextual adaptations. Overall, participants were positive about the appropriateness, feasibility, and acceptability of the program. Participants deemed the physical activity enhancement programs in both communities feasible, thus indicating potential for the further implementation of the program. This research provides new insight into ways of enhancing physical activity in older adults and people with disabilities. Such insight could be used to customize such programs to specific needs.</p>","PeriodicalId":51073,"journal":{"name":"Journal of Aging and Physical Activity","volume":" ","pages":"1-9"},"PeriodicalIF":1.4,"publicationDate":"2025-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143524892","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Acute Effects of Static Stretching on Handgrip Strength and Wrist Joint Flexibility in Physically Active Older Women.","authors":"Ty B Palmer, Bailey M Palmer","doi":"10.1123/japa.2024-0344","DOIUrl":"https://doi.org/10.1123/japa.2024-0344","url":null,"abstract":"<p><strong>Background/objective: </strong>The muscle strength and flexibility responses to stretching in older adults are unclear. We aimed to examine the acute effects of static stretching on handgrip strength and wrist joint flexibility in older women.</p><p><strong>Methods: </strong>Twenty physically active older women (68 ± 6 years) performed handgrip contractions and wrist joint flexibility assessments before and after a control condition (quiet resting) and an experimental condition of static stretching for 30 s. Peak force and rate of force development variables were obtained from each contraction. Wrist joint range of motion was determined from the flexibility assessments.</p><p><strong>Results: </strong>There were no significant changes in handgrip peak force or rate of force development variables after the stretching treatment (p = .11-.88). There was, however, a significant stretch-induced increase in wrist joint range of motion (p < .01).</p><p><strong>Conclusion: </strong>These findings indicate that a 30-s bout of static stretching may be an effective intervention for increasing wrist joint flexibility without decreasing handgrip strength. Significance/Implications: The results of our study may have important implications for creating stretching interventions that can be used as part of a warm-up routine to help attenuate the negative effects of age on range of motion. Such interventions may be beneficial for improving functional performance and reducing the risk of injury in older populations.</p>","PeriodicalId":51073,"journal":{"name":"Journal of Aging and Physical Activity","volume":" ","pages":"1-8"},"PeriodicalIF":1.4,"publicationDate":"2025-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143524887","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Luz A Arcila Castaño, Vanessa Fonseca Vilas-Boas, Vivian Castillo De Lima, Hélio J Coelho-Júnior, Marco C Uchida
{"title":"Sarcopenia-Related Parameters in Older Adults With End-Stage Renal Disease: A Case-Control Study.","authors":"Luz A Arcila Castaño, Vanessa Fonseca Vilas-Boas, Vivian Castillo De Lima, Hélio J Coelho-Júnior, Marco C Uchida","doi":"10.1123/japa.2024-0298","DOIUrl":"https://doi.org/10.1123/japa.2024-0298","url":null,"abstract":"<p><strong>Objective: </strong>Examine the impact of hemodialysis therapy on physical function and body composition after 6 months in community-dwelling older adults with and without chronic kidney disease (CKD).</p><p><strong>Methods: </strong>A case-control study was conducted to assess physical function in older adults on hemodialysis therapy (hemodialysis-dependent CHD patients [HD]) compared with robust older adults without CKD. The study included 23 HD patients (68.8 ± 5.2 years) and 25 control group participants (68.1 ± 6.3 years). Physical function and body composition were evaluated using standard tests and bioelectrical impedance analysis, respectively.</p><p><strong>Results: </strong>Significant differences (p < .05) in physical function were observed between the groups. The HD group showed markedly slower performance in usual gait speed (38.46% slower), five times sit-to-stand test (104.08% slower), Timed Up and Go test (68.65% slower), Timed Up and Go cognitive (142.30% slower), and one-leg stand balance test on the right leg (52.85% lower). However, there were no significant differences in appendicular skeletal mass muscle and fat mass between the HD and control groups. However, lean mass muscle showed the significant reduction for male CKD patients.</p><p><strong>Conclusion: </strong>Hemodialysis therapy significantly reduces physical function in community-dwelling older adults with CKD, with a high prevalence of mobility impairments observed 6 months after initiating dialysis therapy. Conversely, only lean mass muscle was reduced significantly for male patients.</p><p><strong>Significance: </strong>This study highlights the critical need for targeted interventions to counteract the accelerated decline in physical function and lean muscle mass in older adults with CKD undergoing hemodialysis.</p>","PeriodicalId":51073,"journal":{"name":"Journal of Aging and Physical Activity","volume":" ","pages":"1-7"},"PeriodicalIF":1.4,"publicationDate":"2025-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143473336","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Juan Tortosa-Martinez, Celeste Martinez-Canales, Gema Sanchis-Soler, Vicente J Beltran-Carrillo
{"title":"Physical Activity Barriers and Facilitators for Older Women With Mild Cognitive Impairment and Alzheimer's Disease.","authors":"Juan Tortosa-Martinez, Celeste Martinez-Canales, Gema Sanchis-Soler, Vicente J Beltran-Carrillo","doi":"10.1123/japa.2024-0085","DOIUrl":"https://doi.org/10.1123/japa.2024-0085","url":null,"abstract":"<p><strong>Objectives: </strong>The objective of this qualitative study was to analyze the barriers and facilitators for the practice of physical activity (PA) perceived by older women with Mild Cognitive Impairment and Alzheimer disease.</p><p><strong>Methods: </strong>Semistructured interviews were conducted with 22 female participants and 22 matching family members. Data were analyzed with a conventional content analysis.</p><p><strong>Results: </strong>The barriers for PA identified in this study need to be interpreted from an intersectional perspective, since these participants remained in a particular situation of vulnerability due to not only being Mild Cognitive Impairment/Alzheimer disease participants, but also women and older adults. The main barriers identified were health problems, feelings of insecurity and helplessness in their out-home activities, reliance on the social network, and lack of PA culture and exercise knowledge. The main facilitators were the perceived benefits of PA, social support, currently having more free time, and the doctor's advice of doing PA.</p><p><strong>Conclusions: </strong>Based on the results, recommendations for promoting PA in this population include the following: (a) Promote a more constructive and positive conception of aging, gender roles, and cognitive impairment; (b) provide knowledge about the benefits of PA for this population; and (c) out-home PA with a social component could enhance the positive effects of PA, but exercise at home guided by a qualified professional could be an alternative for being active for those who suffer more from insecurity or dependence.</p>","PeriodicalId":51073,"journal":{"name":"Journal of Aging and Physical Activity","volume":" ","pages":"1-10"},"PeriodicalIF":1.4,"publicationDate":"2025-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143460538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Joilson Meneguci, Lucas Lima Galvão, Cíntia Aparecida Garcia Meneguci, Antonio Paulo Ferreira da Silva, Eduardo da Silva Paula, Jair Sindra Virtuoso Júnior
{"title":"Association of Physical Activity and Sedentary Behavior With Depressive Symptoms in Older Adults: A Structural Equation Modeling in Cross-Sectional Study.","authors":"Joilson Meneguci, Lucas Lima Galvão, Cíntia Aparecida Garcia Meneguci, Antonio Paulo Ferreira da Silva, Eduardo da Silva Paula, Jair Sindra Virtuoso Júnior","doi":"10.1123/japa.2024-0037","DOIUrl":"https://doi.org/10.1123/japa.2024-0037","url":null,"abstract":"<p><strong>Background/objectives: </strong>Few conceptual models demonstrate how the relationship between behavioral factors, especially physical activity (PA) and sedentary behavior (SB), and depressive symptoms occurs in older adults. In this regard, understanding how these relationships occur may help in designing future behavior change interventions. The aim of the present study was to evaluate the associations of PA and SB with depressive symptoms in older adults, accounting for functional capacity, sleep quality, self-esteem, and self-efficacy as possible mediators.</p><p><strong>Methods: </strong>In overall, 466 older adults aged ≥60 years participated in the study with a cross-sectional design. We subjectively assessed depressive symptoms, PA and SB, self-efficacy for walking and PA, instrumental activities of daily living, sleep quality, and self-esteem. Structural equation modeling was used to investigate the direct and indirect associations of PA and SB with depressive symptoms.</p><p><strong>Results: </strong>Although PA and SB do not have a direct association with depressive symptoms, these behaviors seem to have total effects on the outcome. The association of SB with depressive symptoms was mediated by functional capacity and sleep quality. And the association of PA was mediated by functional capacity and self-esteem.</p><p><strong>Conclusion: </strong>To reduce depressive symptoms in older adults, PA and SB interventions need to promote sleep quality, functional capacity, and self-esteem. Significance/Implications: Interventions that promote the continuation of regular PA and the reduction of time spent in SB should be encouraged, seeking to improve sleep quality and increase functional capacity, in order to reduce the rates of depressive symptoms in older adults.</p>","PeriodicalId":51073,"journal":{"name":"Journal of Aging and Physical Activity","volume":" ","pages":"1-9"},"PeriodicalIF":1.4,"publicationDate":"2025-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143416233","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Saeid Mirzai, Maximilian C Volk, Richard Kazibwe, Mohanad Gabani, Christopher L Schaich, Racquel Hammonds, Austin Seals, Matthew J Singleton, Joseph Yeboah, Michael D Shapiro, David Herrington, Dalane W Kitzman, Timothy M Hughes, Jeff D Williamson, Stephen B Kritchevsky
{"title":"Association of Gait Speed With Cognitive Outcomes in Older Adults With Hypertension: A Secondary SPRINT MIND Analysis.","authors":"Saeid Mirzai, Maximilian C Volk, Richard Kazibwe, Mohanad Gabani, Christopher L Schaich, Racquel Hammonds, Austin Seals, Matthew J Singleton, Joseph Yeboah, Michael D Shapiro, David Herrington, Dalane W Kitzman, Timothy M Hughes, Jeff D Williamson, Stephen B Kritchevsky","doi":"10.1123/japa.2024-0152","DOIUrl":"https://doi.org/10.1123/japa.2024-0152","url":null,"abstract":"<p><strong>Background/objectives: </strong>Hypertension is linked to slower walking pace and cognitive decline, but the ability of slow gait to predict dementia in older adults with hypertension is unclear. This study examined whether slow baseline gait predicts future cognitive impairment in older adults with hypertension enrolled in the Systolic Blood Pressure Intervention Trial (SPRINT) Memory and Cognition in Decreased Hypertension (MIND) study.</p><p><strong>Methods: </strong>SPRINTMIND randomized adults ≥50 years of age with hypertension to intensive (target systolic blood pressure <120 mmHg) or standard (<140 mmHg) blood pressure control. Baseline gait speed was measured in participants ≥75 years of age. We defined slow gait as speed ≤0.8 m/s. Outcomes were probable dementia (pD), mild cognitive impairment (MCI), and composite pD or MCI.</p><p><strong>Results: </strong>Among 2,351 participants, 33.3% had slow baseline gait. Over median 4-year follow-up, the slow gait group had higher rates of incident pD (13.5% vs 6.4%), MCI (19.4% vs 11.9%), and pD or MCI (29.2% vs 16.3%) compared with normal gait. Adjusted Cox regression models revealed that slow gait was associated with a 1.85-fold higher risk of pD (95% confidence interval [1.37, 2.50], p < .001), 1.52-fold higher risk of MCI (95% confidence interval [1.20, 1.93], p = .001), and 1.61-fold higher risk of pD or MCI (95% confidence interval [1.32, 1.97], p < .001). Intensive blood pressure control did not significantly affect cognitive outcomes in either gait group.</p><p><strong>Conclusion: </strong>Slow gait speed predicts increased cognitive decline risk among older adults with hypertension. Significance/Implications: Gait speed assessment can identify older adults with hypertension at higher risk of cognitive decline, allowing earlier intervention to potentially delay progression.</p>","PeriodicalId":51073,"journal":{"name":"Journal of Aging and Physical Activity","volume":" ","pages":"1-9"},"PeriodicalIF":1.4,"publicationDate":"2025-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143416213","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}