Forschende Komplementarmedizin最新文献

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[Phytotherapy in the German Medical AWMF S3 guidelines - a systematic overview]. [德国医学AWMF S3指南中的植物疗法-系统概述]。
Forschende Komplementarmedizin Pub Date : 2014-01-01 Epub Date: 2014-12-09 DOI: 10.1159/000370079
Petra Klose, Karin Kraft, Holger Cramer, Romy Lauche, Gustav Dobos, Jost Langhorst
{"title":"[Phytotherapy in the German Medical AWMF S3 guidelines - a systematic overview].","authors":"Petra Klose,&nbsp;Karin Kraft,&nbsp;Holger Cramer,&nbsp;Romy Lauche,&nbsp;Gustav Dobos,&nbsp;Jost Langhorst","doi":"10.1159/000370079","DOIUrl":"https://doi.org/10.1159/000370079","url":null,"abstract":"<p><p>In Germany, the interdisciplinary, evidence- and consensus-based medical AWMF S3 guidelines represent the highest available scientific level and have significant impact on patient care. In Germany, Austria, and Switzerland, herbal medicine has a long tradition in medical care. Of notice, the evidence for its efficacy in numerous indications is increasing. This systematic review evaluates to which extent phytotherapy is taken into account in the current S3 guidelines. In all available medical AWMF S3 guidelines, the recommendations/statements on phytotherapeutic options were identified, and 2 independent experts classified them into 3 categories: positive, negative, and open. In addition, comments on side effects and interactions were extracted. Phytotherapeutic options are specified in 40 (31.3 %) out of 128 AWMF S3 guidelines. Phytotherapy was not included in 55 guidelines (42.9%) with potential herbal therapeutic options. From 204 recommendations 139 (68.1%) are negative or remain open. In 27 guidelines (67.5%) phytotherapy is listed in the chapter for complementary and alternative medicine and/or miscellaneous, in 7 guidelines (17.5%) it is mentioned at the end of the recommendations on medical drug therapy, and in 8 guidelines (20.0%) it is listed in the recommendations regarding conventional treatments. Side effects and interactions are stated in 70 out of 204 recommendations (34.3%). Less than half of the currently available medical AWMF S3 guidelines include phytotherapy in their search strategy. Only few positive statements and recommendations on herbal medicine are taken into account. A systematic and comprehensive work up of the existing evidence on the one hand and the consequent incorporation on the other is necessary to appropriately integrate phytotherapy in the German medical guidelines.</p>","PeriodicalId":51049,"journal":{"name":"Forschende Komplementarmedizin","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000370079","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32979045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 10
Evidence for the efficacy of a bioresonance method in smoking cessation: a pilot study. 生物共振方法在戒烟中的有效性证据:一项试点研究。
Forschende Komplementarmedizin Pub Date : 2014-01-01 Epub Date: 2014-08-05 DOI: 10.1159/000365742
Aylin Pihtili, Michael Galle, Caglar Cuhadaroglu, Zeki Kilicaslan, Halim Issever, Feyza Erkan, Tulin Cagatay, Ziya Gulbaran
{"title":"Evidence for the efficacy of a bioresonance method in smoking cessation: a pilot study.","authors":"Aylin Pihtili,&nbsp;Michael Galle,&nbsp;Caglar Cuhadaroglu,&nbsp;Zeki Kilicaslan,&nbsp;Halim Issever,&nbsp;Feyza Erkan,&nbsp;Tulin Cagatay,&nbsp;Ziya Gulbaran","doi":"10.1159/000365742","DOIUrl":"https://doi.org/10.1159/000365742","url":null,"abstract":"<p><strong>Background: </strong>Since the 1970s, MORA bioresonance therapy has globally been applied in the context of complementary medicine for various indications. In this regard, practitioners also report successful application in smoking cessation. The present study aims to verify these reports in a controlled study setting.</p><p><strong>Methods: </strong>In order to achieve the aforementioned objective, we subjected the bioresonance method to a prospective, placebo-controlled, double-blind, parallel-group study involving 190 smokers. In both study groups (placebo n = 95; active bioresonance group; n = 95) the course of treatment and study conditions were standardized.</p><p><strong>Results: </strong>1 week (77.2% vs. 54.8%), 2 weeks (62.4% vs. 34.4%), 1 month (51.1% vs. 28.6%), and 1 year (28.6% vs. 16.1%) after treatment, the success rate in the verum group differed significantly from the results in the placebo group. Also, the subjective health condition after treatment and subjective assessment of efficacy, polled after 1 week, were significantly more positive among participants in the active bioresonance therapy group than among those in the placebo group. Adverse side effects were not observed.</p><p><strong>Conclusion: </strong>According to the findings attained by this pilot study, bioresonance therapy is clinically effective in smoking cessation and does not show any adverse side effects.</p>","PeriodicalId":51049,"journal":{"name":"Forschende Komplementarmedizin","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000365742","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32676896","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 14
Acupuncture in treating sudden sensorineural hearing loss: a report of 2 cases. 针刺治疗突发性感音神经性耳聋2例报告。
Forschende Komplementarmedizin Pub Date : 2014-01-01 Epub Date: 2014-08-15 DOI: 10.1159/000365982
Nanbin Huang, Changwei Li
{"title":"Acupuncture in treating sudden sensorineural hearing loss: a report of 2 cases.","authors":"Nanbin Huang,&nbsp;Changwei Li","doi":"10.1159/000365982","DOIUrl":"https://doi.org/10.1159/000365982","url":null,"abstract":"<p><strong>Background: </strong>Two cases of sudden sensorineural hearing loss (SSHL) in left ear diagnosed by an ear, nose, and throat specialist are presented.</p><p><strong>Case report: </strong>The first patient was a 22-year-old male college student with moderately severe hearing loss, tinnitus, and a feeling of fullness in the ear for 5 days. The other patient was a 48-year-old male pilot with severe hearing loss, tinnitus, and fullness in the ear for 7 days. Both patients did not respond to medical treatment, and the hearing loss became even worse. The patients were then treated with acupuncture 5 and 7 days, respectively, after hearing loss had developed. Electroacupuncture was applied to ear and neck once per day for both patients.</p><p><strong>Results: </strong>Fullness in ear disappeared during the first treatment in both cases, and the first patient also felt great improvement in hearing during the first treatment. After 10 treatments, the first patient had recovered. In the other patient, hearing had greatly improved after 19 treatments.</p><p><strong>Conclusion: </strong>Acupuncture may be worth trying in patients with SSHL who do not respond to routine medical treatment.</p>","PeriodicalId":51049,"journal":{"name":"Forschende Komplementarmedizin","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000365982","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32676897","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
[Natural medicine for the soul]. [心灵的天然良药]。
Forschende Komplementarmedizin Pub Date : 2014-01-01
{"title":"[Natural medicine for the soul].","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":51049,"journal":{"name":"Forschende Komplementarmedizin","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32461737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Between empiricism and evidence - ( re ) activation of veterinary phytotherapy]. [在经验主义和证据之间-(重新)兽医植物疗法的激活]。
Forschende Komplementarmedizin Pub Date : 2014-01-01 Epub Date: 2014-07-04 DOI: 10.1159/000362396
Michael Walkenhorst, Christian R Vogl, Brigitte Vogl-Lukasser, Sabine Vollstedt, Cäcilia Brendieck-Worm, Silvia Ivemeyer, Franziska Klarer, Beat Meier, Kathrin Schmid, Monika Disler, Tinetta Bischoff, Matthias Hamburger, Stephan Häsler, Elisabeth Stöger
{"title":"[Between empiricism and evidence - ( re ) activation of veterinary phytotherapy].","authors":"Michael Walkenhorst,&nbsp;Christian R Vogl,&nbsp;Brigitte Vogl-Lukasser,&nbsp;Sabine Vollstedt,&nbsp;Cäcilia Brendieck-Worm,&nbsp;Silvia Ivemeyer,&nbsp;Franziska Klarer,&nbsp;Beat Meier,&nbsp;Kathrin Schmid,&nbsp;Monika Disler,&nbsp;Tinetta Bischoff,&nbsp;Matthias Hamburger,&nbsp;Stephan Häsler,&nbsp;Elisabeth Stöger","doi":"10.1159/000362396","DOIUrl":"https://doi.org/10.1159/000362396","url":null,"abstract":"a Departement fur Nutztierwissenschaften, Forschungsinstitut fur biologischen Landbau (FiBL), Frick, Schweiz, b Institut fur Okologischen Landbau, Department fur Nachhaltige Agrarsysteme, Universitat fur Bodenkultur, Wien, Osterreich, c Bokholt-Hanredder, d Niederkirchen, e Fachgebiet Nutztierethologie und Tierhaltung, Fachbereich Okologische Agrarwissenschaften, Universitat Kassel, Witzenhausen, Deutschland, f Institut fur Biotechnologie, Departement Life Sciences und Facility Management, Zurcher Hochschule fur Angewandte Wissenschaften ZHAW, Wadenswil , g Department of Pharmaceutical Sciences, University of Basel, h Schweizerische Vereinigung fur Geschichte der Veterinarmedizin, Gasel, Schweiz, i Feldkirchen, Osterreich","PeriodicalId":51049,"journal":{"name":"Forschende Komplementarmedizin","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000362396","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32494547","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 10
[Mesembryanthemum crystallinum L. as dermatologically effective medicinal plant - first results from 3 pilot studies]. [作为一种皮肤有效的药用植物- 3项初步研究的初步结果]。
Forschende Komplementarmedizin Pub Date : 2014-01-01 Epub Date: 2014-12-10 DOI: 10.1159/000369909
Christa Raak, Friedrich Molsberger, Ulrike Heinrich, Mathias Bertram, Thomas Ostermann
{"title":"[Mesembryanthemum crystallinum L. as dermatologically effective medicinal plant - first results from 3 pilot studies].","authors":"Christa Raak,&nbsp;Friedrich Molsberger,&nbsp;Ulrike Heinrich,&nbsp;Mathias Bertram,&nbsp;Thomas Ostermann","doi":"10.1159/000369909","DOIUrl":"https://doi.org/10.1159/000369909","url":null,"abstract":"<p><strong>Background: </strong>Apart from well-known medical plants of rational phytotherapy there is a variety of plants, such as Mesembryanthemum crystallinum L., whose potential effects are not examined sufficiently to date. Therefore, in 3 pilot studies we investigated the dermatological effect of an extract of M. crystallinum (Mesem Cream).</p><p><strong>Materials and methods: </strong>In a retrospective user survey and a pre-post study with 6 persons in a wheelchair the efficacy profile of Mesem Cream was investigated. In a third placebo-controlled pilot study changes in skin hydration was measured using corneometer measurement in 6 healthy volunteers with dry skin.</p><p><strong>Results: </strong>Compared to untreated skin, corneometer measurement revealed a significant increase of skin hydration with Mesem Cream (25.8 ± 5.8 pre to 46.6 ± 9.2 post treatment vs. 26.3 ± 6.0 pre to 33.8 ± 6.0 post treatment) as well as a statistical trend (p=0.11; t-Test) compared to basic cream (25.1 ± 4.7 pre to 41.9 ± 7.3 post treatment). Improvement in skin hydration was also found in 17 of 29 survey participants. Further, the volunteers in the wheelchair showed significant improvements in their subjectively rated skin softness and hydration level.</p><p><strong>Conclusion: </strong>These pilot studies investigated skin hydrating effects of the traditional medical plant M. crystallinum. Although the results were promising, they have to be interpreted with caution in particular due to low sample size. Further, study design should be more clear-cut and focus skin hydration as a main outcome parameter in more detail.</p>","PeriodicalId":51049,"journal":{"name":"Forschende Komplementarmedizin","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000369909","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32978565","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
A roadmap for CAM research towards the horizon of 2020. 2020年CAM研究的路线图。
Forschende Komplementarmedizin Pub Date : 2014-01-01 Epub Date: 2014-03-24 DOI: 10.1159/000358105
Harald Walach, Sirpa Pietikäinen
{"title":"A roadmap for CAM research towards the horizon of 2020.","authors":"Harald Walach,&nbsp;Sirpa Pietikäinen","doi":"10.1159/000358105","DOIUrl":"https://doi.org/10.1159/000358105","url":null,"abstract":"CAMbrella was the first pan-European research project that systematically evaluated the state of usage, motivation, provision, and regulation of CAM usage in European countries. It also documented the need and the way forward for research in Europe. Some of the finest minds in European CAM research were either part of the consortium or were invited as experts to some of the specialist meetings. Thus, CAMbrella formulates a consensus never seen in European research on this topic before. Results of the work packages – most of them systematic reviews – have been published, also in open access format in FORSCHENDE KOMPLEMENTARMEDIZIN [1]. Now, the final piece, roadmap 2020, has been published and is available online [2]. This roadmap sums up the findings briefly and points towards the future direction of research. You do not have to be a wizard to understand the most important message: European research was once at the forefront of research in this topic, and it is in danger of becoming last, being overtaken by countries such as USA, Canada, Australia, India, China, Africa even. All these countries and continents have either formulated a research agenda (Canada), or have dedicated institutes that have funding available (USA, Australia, India), or have at least understood that traditional approaches to medicine are a resource (India, China, Africa). In USA, a steady funding stream of approximately USD 120 million per year enables the maintenance of a proper research agenda. What about Europe? Apart from isolated pockets full of projects: nothing. UK, often a forerunner, spends 0.0085% of its research budget on CAM research, where 10% of the population use CAM approaches each year and approximately 50% are lifetime users. The figures are even lower for Germany which is among the countries of the highest prevalence of usage [3]. European researchers were among those that were invited to the first foundational conferences of the Office of Alternative Medicine at the National Institutes of Health (NIH) in the 1990s, because of innovative research design and because CAM research has had a long tradition in Europe. What happened afterwards? The USA saw that this was a growth market, supported research by founding a National Center for CAM research (NCCAM), and became world leader in research in this area [4]. And Europe? A few projects to have a placating answer for the public in the drawer, but nothing serious. We feel we are at the brink of an important junction in history. If we want to continue improving the health of European citizens, we cannot ignore that CAM is a potentially important player, being used by up to 60% of the population [5]. It is important to realize that we know very little about its comparative effectiveness vis-a-vis conventional approaches. We do not know whether and when it would be beneficial for patients to integrate CAM treatments into their conventional treatment regime. We do not know how many patients would want that. We do","PeriodicalId":51049,"journal":{"name":"Forschende Komplementarmedizin","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000358105","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32359330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
[The use of complementary and alternative therapies in Germany - a systematic review of nationwide surveys]. [德国补充和替代疗法的使用——对全国调查的系统回顾]。
Forschende Komplementarmedizin Pub Date : 2014-01-01 Epub Date: 2014-03-24 DOI: 10.1159/000360917
Klaus Linde, Anna Alscher, Clara Friedrichs, Stefanie Joos, Antonius Schneider
{"title":"[The use of complementary and alternative therapies in Germany - a systematic review of nationwide surveys].","authors":"Klaus Linde,&nbsp;Anna Alscher,&nbsp;Clara Friedrichs,&nbsp;Stefanie Joos,&nbsp;Antonius Schneider","doi":"10.1159/000360917","DOIUrl":"https://doi.org/10.1159/000360917","url":null,"abstract":"<p><p>In this systematic review we aimed to summarize surveys investigating the use of complementary and alternative medicine (CAM) methods in the general German population and by physicians and lay practitioners. Nationwide surveys (using random, panel, or quota sampling methods) published since 1993 investigating the CAM use among the population and healthcare providers in Germany were identified through searches in PubMed, Google Scholar, Google, citation screening, and expert contacts. In addition we collected publicly available data from official nationwide health statistics and market statistics. 16 surveys of the general adult population and 4 surveys among physicians met inclusion criteria. The use of CAM among general population in the previous years varied between 40 and 62%. General practitioners and orthopedic specialists in private practice seem to provide CAM therapies widely and more frequently than other physician groups, with herbal medicine and chirotherapy being the most frequently used treatments. We could not identify any surveys of lay practitioners. The available surveys provide clear evidence of the widespread use of CAM methods in Germany both by the general population and by physicians. In recent years the use of CAM methods does not seem to increase any longer; for some methods (particularly herbal remedies) the use seems to be declining.</p>","PeriodicalId":51049,"journal":{"name":"Forschende Komplementarmedizin","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000360917","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32359310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 18
Before and after CAMbrella. 在CAMbrella之前和之后。
Forschende Komplementarmedizin Pub Date : 2014-01-01 Epub Date: 2014-03-24 DOI: 10.1159/000358104
Nand De Herdt, Susanne Schunder-Tatzber
{"title":"Before and after CAMbrella.","authors":"Nand De Herdt,&nbsp;Susanne Schunder-Tatzber","doi":"10.1159/000358104","DOIUrl":"https://doi.org/10.1159/000358104","url":null,"abstract":"The idea of fostering CAM in terms of an EU-funded project was influenced by SST’s research and EU project work in the field of occupational health. At the Viennese Academy of Integrative Medicine it was Wolfgang Marktl and Bettina Reiter who searched for potential international partners willing to support a CAM project at EU level. The first meeting for ‘CAM in FP 7’ (European Research Frame Programme No. 7) took place in June 2004 in Vienna, where 15 participants from 5 European countries met to make themselves familiar with FP 7, which at that time was in an early preparatory stage, and discussed ideas on how CAM might be integrated in the next framework program. It has been decided that a European umbrella organization consisting of institutions that are interested in supporting CAM research should be established in order to organize the work of the research groups for CAM in FP 7. In the course of these efforts, EURICAM (European Research Initiative for Complementary and Alternative Medicine) was set up, developing new ideas on how to promote CAM research on an institutional level. The results were presented at international conferences, e.g., a symposium in Exeter in November 2004, or at different CAM research meetings, e.g., the Forum Meeting in Essen in January 2005. Contact was established with other umbrella organizations of CAM at European level, such as the ECPM (European Council of Plurality of Medicine), EFCAM (European Forum for Complementary Medicine), ECHT (European Committee for Homeopathy), and ECHAMP (European Coalition on Homeopathic and Anthroposophic Medicinal Products). Several meetings with stakeholders were held in Brussels where potential political efforts had been discussed, aiming at supporting a legal basis for CAM research. The EPHA (European Public Health Alliance) supported these efforts and provided important information on relevant European institutions. The preparatory FP 7 documents (amendment proposal June 28, 2006) contained an amendment on CAM where the aims and scope of CAM research were defined as follows: ‘Translating clinical research outcome into clinical practice. To understand how to create the knowledge base for clinical decision-making and how to translate outcomes of clinical research into clinical practice and especially addressing patient safety and the better use of medicines (including some aspects of pharmacovigilance and scientifically tested complementary and alternative medicines) as well as the specificities of children, women and elderly population.’ On December 18, 2006, the European Parliament and the Council made the final decision on CAM in FP 7. After 3 years of effort, the CAM research community finally had the opportunity to launch an EU-funded CAM research project. The development of the research program had to be accelerated in order to be prepared for the call for CAM research projects. For this purpose, first strategy meetings of researchers took place and meetings with scient","PeriodicalId":51049,"journal":{"name":"Forschende Komplementarmedizin","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000358104","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32359331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Effects of chronic Bryophyllum pinnatum administration on Wistar rat pregnancy. 慢性苔藓对Wistar大鼠妊娠的影响。
Forschende Komplementarmedizin Pub Date : 2014-01-01 Epub Date: 2014-06-16 DOI: 10.1159/000363709
Jorge Kioshi Hosomi, Ricardo Ghelman, Marisa Pascale Quintino, Eduardo de Souza, Mary Uchiyama Nakamura, Antonio Fernandes Moron
{"title":"Effects of chronic Bryophyllum pinnatum administration on Wistar rat pregnancy.","authors":"Jorge Kioshi Hosomi,&nbsp;Ricardo Ghelman,&nbsp;Marisa Pascale Quintino,&nbsp;Eduardo de Souza,&nbsp;Mary Uchiyama Nakamura,&nbsp;Antonio Fernandes Moron","doi":"10.1159/000363709","DOIUrl":"https://doi.org/10.1159/000363709","url":null,"abstract":"<p><strong>Background: </strong>Drugs used in preterm labor (PTL) have side effects. Research into new tocolytic agents is recommended. The plant Bryophyllum pinnatum (Lam.) Oken (Kalanchoe pinnata (Lam.) Pers) is used in Anthroposophic Medicine for PTL, insomnia, and emotional disturbances. The aim of this study was to evaluate the effects of B. pinnatum mother tincture (MT) on Wistar rats and their fetuses throughout pregnancy.</p><p><strong>Method: </strong>Sixty animals were divided into 6 equal groups: controls C1 and C2 received 1 and 25 × the maximum daily dose of a 30% ethanol / water solution, serving as vehicle of B. pinnatum MT; B1 and B2 received 1 and 25 × the maximum daily dose of B. pinnatum MT; and B3 and B4 received 50 and 100 × B. pinnatum concentrate. The following parameters were assessed: weight gain; maternal and fetal mortality; implantations and resorptions; number and weight of fetuses and placentas; major external fetal malformations.</p><p><strong>Results: </strong>Rat weight gain (excluding fetal and placental weight) was higher in group B4 and lower in group B2. There were no maternal or fetal deaths and no group differences in implantations and resorptions or number and weight of fetuses and placentas. No macroscopic fetal abnormalities were observed at the 4 dosage levels investigated.</p><p><strong>Conclusion: </strong>Daily administration of B. pinnatum MT at high doses to pregnant Wistar rats interfered with maternal weight gain and did not interfere with fetal compartment.</p>","PeriodicalId":51049,"journal":{"name":"Forschende Komplementarmedizin","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000363709","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32531885","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 11
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