Forschende Komplementarmedizin最新文献

{"title":"[Complementary, alternative and integrative therapies in medical guidelines - the guideline \"Diagnosis and treatment of ulcerative colitis\" as an example of successful integration].","authors":"Holger Cramer, Romy Lauche, Petra Klose, Gustav Dobos, Jost Langhorst","doi":"10.1159/000358577","DOIUrl":"https://doi.org/10.1159/000358577","url":null,"abstract":"Die aktuelle Leitlinie «Diagnostik und Therapie der Colitis ulcerosa» wurde im September 2011 unter Federfuhrung der Deutschen Gesellschaft fur Verdauungsund Stoffwechselkrankheiten (DGVS) und Mitarbeit der Deutschen Gesellschaft fur Pathologie (DGP), der Deutschen Gesellschaft fur Allgemeinund Viszeralchirurgie (DGVC), der Gesellschaft fur padiatrische Gastroenterologie und Ernahrung (GPGE) sowie der Deutschen Gesellschaft fur Ernahrungsmedizin (DGEM) vorgelegt. Die nachste Aktualisierung ist fur September 2016 avisiert; die gegebenen Empfehlungen werden also noch eine geraume Weile den Goldstandard in der Therapie der Colitis ulcerosa darstellen [1]. Fur eine Reihe komplementarmedizinischer Verfahren enthielt die Leitlinie evidenzbasierte positive Empfehlungen, die einen hinreichenden Konsens in der Leitlinienkonferenz fanden (Tab. 1). So wurden abgeschwacht positive Empfehlungen fur das Phytotherapeutikum Plantago ovata gegeben, das sich in einer klinischen Studie Mesalazin in der remissionserhaltenden Behandlung als ebenburtig erwies (Empfehlung 10.16); ebenso fur Curcumin, das in der remissionserhaltenden Behandlung komplementar zu 5-ASA empfohlen wird (Empfehlung 10.15). Ein Problem in der Anwendung von Curcumin in Deutschland ergibt sich allerdings daraus, dass in der japanischen Studie [2], auf der die Empfehlung beruht, Curcumin in einer Dosis von 2 × 1 g/Tag eingesetzt wurde, wahrend die in Deutschland verfugbaren Praparate deutlich geringere Dosierungen enthalten. Daneben gibt die Leitlinie eine abgeschwacht positive Empfehlung fur Akupunktur in Kombination mit Moxibustion als komplementare Therapie im leichten bis moderaten Schub (Empfehlung 10.18) sowie fur eine multimodale komplementare Mind-Body-Therapie zur Verbesserung der Lebensqualitat (Empfehlung 10.17). Letztere Empfehlung ist bisher nahezu einzigartig in Deutschland; erstmals wird hier eine multimodale MindBody-Therapie empfohlen, wie sie in Deutschland in integrativmedizinischen Kliniken angeboten wird [3]. Die Empfehlung basiert unter anderem auf einer deutschen randomisierten Studie [4, 5], die zeigen konnte, dass ein multimodales Lebensstilmodifikationsprogramm mit Elementen der Mind-Body-Medizin die Lebensqualitat von Patienten in Remission oder mit geringer Krankheitsaktivitat in klinisch relevantem Umfang steigern kann. Weitere komplementarmedizinische Verfahren, inklusive weiterer Phytotherapeutika und einzelner Verfahren der Mind-Body-Medizin wie Yoga oder Qigong, konnten aufgrund der unzureichenden Datenlage nicht empfohlen werden (Empfehlung 10.20). Ein potenzieller Kandidat fur zukunftige Aktualisierungen der Leitlinie scheint die Behandlung mit Eiern des Schweinepeitschenbandwurms (Trichuris suis ovata) zu sein, die in einer randomisierten Studie im leichten bis moderaten Schub die Krankheitsaktivitat signifikant starker senken konnte als Placebo, derzeit aber – vor dem Hintergrund der fehlenden Zulassung in Deutschland – nicht generell empfohlen wird (Empfehlun","PeriodicalId":51049,"journal":{"name":"Forschende Komplementarmedizin","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000358577","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40289825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Stress-relieving effects of short-term balneotherapy - a randomized controlled pilot study in healthy adults.","authors":"Franziska Matzer,&nbsp;Eva Nagele,&nbsp;Babak Bahadori,&nbsp;Karl Dam,&nbsp;Christian Fazekas","doi":"10.1159/000360966","DOIUrl":"https://doi.org/10.1159/000360966","url":null,"abstract":"<p><strong>Background: </strong>Stress-relieving effects of balneotherapy compared to progressive muscle relaxation (PMR) and to resting were investigated by measuring subjective relaxation and salivary cortisol. It was also examined whether participants with a high versus low stress level would have a different relaxation response.</p><p><strong>Methods: </strong>A sample of healthy volunteers was randomized to balneotherapy, PMR, or a resting control group, each intervention lasting for 25 min. Pre- and post-intervention salivary cortisol samples were collected, and participants rated their status of relaxation on a quantitative scale. In addition, 3 questionnaires were applied to detect participants' stress level and bodily complaints.</p><p><strong>Results: </strong>49 healthy participants were recruited (65.3% female). In a pre-post comparison, salivary cortisol decreased (F = 23.53, p < 0.001) and subjective relaxation ratings increased (F = 132.18, p < 0.001) in all 3 groups. Study participants in the balneotherapy group rated themselves as more relaxed after the intervention as compared to the other groups (F = 5.22, p < 0.009). Participants with a high versus low stress level differed in somatic symptoms and in morning cortisol levels, but showed a similar relaxation response.</p><p><strong>Conclusion: </strong>Findings suggest that compared to PMR and resting, balneotherapy seems to be more beneficial with regard to subjective relaxation effects and similarly beneficial with regard to a decrease in salivary cortisol.</p>","PeriodicalId":51049,"journal":{"name":"Forschende Komplementarmedizin","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000360966","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32359309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Efficacy in phytotherapy].","authors":"Reinhard Saller,&nbsp;Jörg Melzer,&nbsp;Günter Meng,&nbsp;Ursula von Mandach,&nbsp;Karin Fürer,&nbsp;Herbert Schwabl,&nbsp;Cecile Vennos","doi":"10.1159/000362394","DOIUrl":"https://doi.org/10.1159/000362394","url":null,"abstract":"ePerinatale Pharmakologie, UniversitatsSpital Zurich, f Padma AG, Hinwil, Schweiz Die moderne Phytotherapie ist im Rahmen ihrer materiellen Moglichkeiten ein durchaus forschungsaffiner Therapiebereich. Neben einem mehrdimensionalen Ansatz, anhand einer Heilpflanze beispielhaft ein potentiel les phytotherapeutisches Therapiespektrum auszuloten geht es vor allem um eine reflektierte wissenschaftliche Auseinandersetzung mit Methodologie, Aussagekraft und notwendigen Modifizierungen von Metaanalysen sowie mit Ansatzen aus der Versorgungsforschung. Beide Vorgehensweisen bilden derzeit auch in der Phytotherapie einen viel beachteten Fokus der klinischen und klinisch-epidemiologischen Forschung. Die Metaanalysen beschaftigen sich naturgemas mit bereits vorhandenen Studiendaten und treffen dabei jeweils eine begrundete wenngleich selektive und forscherbezogen durchaus subjektive Auswahl. Spezifische phytothera peutische Gesichtspunkte wie z.B. Besonderheiten von Extrakten oder Vergleichbarkeit von Phytotherapeutika werden bislang kaum wissenschaftlich angemessen berucksichtigt. In der Versorgungsforschung, die nicht durch fixe Studienvorgaben eingeschrankt ist, stehen Daten aus der flexiblen und variablen Praxis im Vorder grund. Dieser Ansatz kann es, bei allen Einschrankungen, ermoglichen, neue und therapierelevante Gesichtspunkte zu entdecken, z.B. im Hinblick auf Dosierungen. Der authentische Charakter von Phytotherapeutika als Vielstoffgemische in stofflicher und funktioneller Hin sicht mit genuinen pleiotropen Eigenschaften wird bislang in der Forschung, vor allem der pharmakologischen Forschung, nur selten adaquat aufgegriffen. Vergleichbar werden pflanzliche Arzneimittel noch im mer praferentiell unter dem eher realitatsfernen Grundsatz gesehen: «one drug, one indication». Die Betrachtung und Beforschung von Phytotherapeutika als Netzwerkarzneimittel mit pleiotropen Signaturen weist auf zukunfstrachtige Vorgehensweisen hin.","PeriodicalId":51049,"journal":{"name":"Forschende Komplementarmedizin","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000362394","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32494545","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical effects of needle-pricking therapy on peripheral facial paralysis.","authors":"You-Jung Kwon,&nbsp;Seunghoon Lee,&nbsp;Sangmin Park,&nbsp;Ungin Lee,&nbsp;Sung-Keun Lim,&nbsp;Dongwoo Nam,&nbsp;Sanghoon Lee","doi":"10.1159/000358742","DOIUrl":"https://doi.org/10.1159/000358742","url":null,"abstract":"<p><strong>Background: </strong>The aim of this study was to investigate the effects of needle-pricking therapy on peripheral facial paralysis.</p><p><strong>Methods: </strong>This study included 162 patients with peripheral facial paralysis, 107 of whom were treated with usual care (conventional and alternative treatments) and 55 of whom were additionally treated with needle-pricking therapy on 3 specific extra-meridian acupuncture points known as 'Samjoong' (Sānchóng in Chinese). We evaluated changes in facial motor functions and sequelae using the Yanagihara and gross House-Brackmann grading systems before and after treatments.</p><p><strong>Results: </strong>Yanagihara score and House-Brackmann grade significantly improved after treatments in both groups. However, the needle-pricking therapy group showed greater improvements in Yanagihara score and House-Brackmann grade than the usual care group.</p><p><strong>Conclusion: </strong>Our results suggest that Samjoong needle-pricking therapy could be applied as an adjunct therapy to usual care for patients with peripheral facial paralysis.</p>","PeriodicalId":51049,"journal":{"name":"Forschende Komplementarmedizin","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000358742","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40288676","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Interpersonal attention management inventory: a new instrument to capture different self- and external perception skills].","authors":"Klaus Blaser,&nbsp;Milena Zlabinger,&nbsp;Thilo Hinterberger","doi":"10.1159/000358176","DOIUrl":"https://doi.org/10.1159/000358176","url":null,"abstract":"<p><strong>Background: </strong>The Interpersonal Attention Management Inventory (IAMI) represents a new instrument to capture self- and external perception skills. The underlying theoretical model assumes 3 mental locations of attention (the intrapersonal space, the extrapersonal space, and the external intrapersonal space) of the other.</p><p><strong>Methods: </strong>The IAMI was studied regarding its factor structure; it was shortened and statistical values as well as first reference values were calculated based on a larger sample (n = 1089).</p><p><strong>Results: </strong>By factor analysis, the superordinate scales could be widely validated. The shortened version with 31 items and 3 superordinate scales shows a high reliability of the global value (Cronbach's α = 0.81) and, regarding the convergent validity, a modest correlation (r = 0.41) of the global value and mindfulness, measured with the Freiburg Mindfulness Inventory (FMI).</p><p><strong>Conclusions: </strong>Further validation studies are invited so that the IAMI can be used as an instrument for (course) diagnosis in the therapy of psychiatric disorders as well as for research in social neuroscience, e.g., in investigations on mindfulness, compassion, empathy, theory of mind, and self-boundaries.</p>","PeriodicalId":51049,"journal":{"name":"Forschende Komplementarmedizin","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000358176","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40288679","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[The vitamins B₆, B₁₂ and folic acid - successful strategy for increasing vitality?].","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":51049,"journal":{"name":"Forschende Komplementarmedizin","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32649555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An open-label pilot study of homeopathic treatment of attention deficit hyperactivity disorder in children and youth.","authors":"David Brulé,&nbsp;Lauren Sule,&nbsp;Beth Landau-Halpern,&nbsp;Violeta Nastase,&nbsp;Umesh Jain,&nbsp;Sunita Vohra,&nbsp;Heather Boon","doi":"10.1159/000368137","DOIUrl":"https://doi.org/10.1159/000368137","url":null,"abstract":"<p><strong>Background: </strong>An open-label pilot study of individualized homeopathy for attention deficit hyperactivity disorder (ADHD) was conducted to assess the potential for future studies with a focus on the feasibility of the recruitment plan and outcome measure schedules; identification of any group characteristics of participants who respond significantly to the therapy; and establishing the length of time required for an improvement in ADHD symptoms.</p><p><strong>Patients and methods: </strong>Participants (aged 6-16) were recruited through community advertisement and outreach. Participants completed 1 screening and 9 individualized homeopathic follow-up consultations. ADHD symptoms were assessed using the Conners 3 - Parent Questionnaire administered at each consultation. The pre- and post-study difference in Conners Global Index - Parent (CGI-P) T-score was evaluated for each participant. Baseline data of those who showed a statistically significant improvement (responders) were compared to those who did not (non-responders).</p><p><strong>Results: </strong>35 participants were enrolled over 11 months. 80% completed all 10 consultations in a median of 12.1 months. 63% had a statistically significant improvement in the primary outcome, first occurring after a mean of 4.5 visits. Overall scores for participants completing at least 2 data points decreased from a baseline median of 85.5 to 74.0 (p < 0.001, CI 95%). There were no significant baseline differences between responders and non-responders. No serious adverse events related to the therapy were reported.</p><p><strong>Conclusion: </strong>The change in the median CGI-P T-score from baseline to the end of this open-label pilot study was statistically significant. The research methods are feasible. Future studies are warranted.</p><p><strong>Trial registration: </strong>NCT01141634.</p>","PeriodicalId":51049,"journal":{"name":"Forschende Komplementarmedizin","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000368137","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32839413","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Treatment of organic livestock with medicinal plants: a systematic review of European ethnoveterinary research.","authors":"Maria Mayer,&nbsp;Christian R Vogl,&nbsp;Michele Amorena,&nbsp;Matthias Hamburger,&nbsp;Michael Walkenhorst","doi":"10.1159/000370216","DOIUrl":"https://doi.org/10.1159/000370216","url":null,"abstract":"<p><strong>Background: </strong>The EC Regulation for Organic Farming states that organic livestock should be treated preferably with phytotherapeutic products. In spite of the high importance of organic livestock in Europe, primarily ruminants, today almost no phytotherapeutic product is registered for livestock. Also, information regarding veterinary phytotherapy is rare. The aim of this paper is to find approaches to cope with health problems of organic ruminants in Europe on the basis of findings from the European ethnoveterinary medicine (EuEVM).</p><p><strong>Methods: </strong>A systematic review of ethno-biomedicinal papers was conducted with the aid of the Scopus database, and 75 papers, from European countries were analyzed regarding ethnoveterinary information.</p><p><strong>Results: </strong>A total of 590 plant species referring to 102 different plant families are reported to be used for animal treatment, with Asteraceae, Fabaceae and Lamiaceae being the most important families. The traditional use of some plant species (e.g. mallow, chamomile, wormwood) corresponds with findings from recent scientific literature. The large number of less studied plant species, such as white lupin as an antiparasitic herb, and Helleborus spp. as potential immunostimulatory agent, opens an interesting field for future research.</p><p><strong>Conclusions: </strong>In general, EuEVM provides interesting treatment approaches for gastrointestinal and dermatological disorders as well as parasitosis. Findings regarding disorders of female genital or respiratory tract are less consistent. Nevertheless, EuEVM offers a solid basis for stimulating research in veterinary phytotherapy in Europe with a perspective to solve animal health problems in organic or even nonorganic ruminant production.</p>","PeriodicalId":51049,"journal":{"name":"Forschende Komplementarmedizin","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000370216","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32978566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Solidagoren® Liquid in uncomplicated urinary tract infections].","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":51049,"journal":{"name":"Forschende Komplementarmedizin","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33100423","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Using hospital data and routines to estimate costs and effects of integrative care programmes for chronic pain and stress disorders--a feasibility study.","authors":"Tobias Sundberg,&nbsp;Torkel Falkenberg","doi":"10.1159/000363635","DOIUrl":"https://doi.org/10.1159/000363635","url":null,"abstract":"<p><strong>Background: </strong>Evidence of cost and effects for comprehensive hospital-based integrative care (IC) is scarce. The aim of this study was to explore the feasibility of using local hospital data and routines to estimate costs and effects of anthroposophic IC programmes for chronic pain and stress disorders in Sweden.</p><p><strong>Methods: </strong>Retrospective analysis of one IC hospital's local administrative registry data. Main outcomes embraced patient demographics, programme duration and costs, patients' health status (EQ-5D index, 0-1) and self-rated health (EQ-5D VAS, 0-100), from hospital admittance to discharge. The use of postal questionnares for collecting follow-up data after hospital discharge was assessed.</p><p><strong>Results: </strong>The IC pain programme had 461 records, all with complete data on costs and duration: average programme cost, EUR 5,925 (95% CI 5,780-6,070), and duration, 17.8 (SD 4.7) days. The IC stress programme had 263 records, all with complete cost and duration data: programme cost, EUR 5,494 (95%CI 5,318-5,671); duration 18.0 (SD 4.7) days. From admittance to discharge, health status improved by 0.23 (95% CI 0.19-0.27) in the pain, and by 0.16 (95% CI 0.12-0.20) in the stress programme. Improvements in self-rated health were 20 (95% CI 18-22), and 21 (95% CI 18-23), respectively. There was a general decrease in questionnaire response rate after hospital discharge, whereby 27-32% of respondents had completed data after 9 months.</p><p><strong>Conclusions: </strong>It was feasible to use hospital registry data to estimate costs and show positive effects of anthroposophic IC programmes for pain and stress disorders in Sweden. Clinical implications and the need for long-term follow-up are discussed.</p>","PeriodicalId":51049,"journal":{"name":"Forschende Komplementarmedizin","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000363635","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32532453","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}