{"title":"Which subtype of functional dyspepsia patients responses better to acupuncture? A retrospective analysis of a randomized controlled trial.","authors":"Tingting Ma, Fang Zeng, Ying Li, Chieh-Mei Wang, Xiaoping Tian, Shuyuan Yu, Ling Zhao, Xi Wu, Min Yang, Dejun Wang, Fanrong Liang","doi":"10.1159/000380983","DOIUrl":"https://doi.org/10.1159/000380983","url":null,"abstract":"<p><strong>Background: </strong>Whether subgroups of functional dyspepsia (FD) should be treated with different approaches is controversially discussed in research. As our previous study has demonstrated the effect of acupuncture in FD treatment, we now further analyze the therapeutic effect of acupuncture in the treatment of postprandial distress syndrome (PDS) and epigastric pain syndrome (EPS).</p><p><strong>Methods: </strong>A retrospective analysis was conducted in 465 eligible PDS patients and 241 EPS patients. 4 acupuncture groups (group A: specific acupoints along the stomach meridian; group B: non-specific acupoints along the stomach meridian; group C: alarm and transport acupoints; group D: specific acupoints along the gallbladder meridian) were compared with a non-acupoint sham acupuncture group and an itopride group. The patients were treated in 5 consecutive sessions per week for 4 weeks and were followed-up for 12 weeks afterwards. Primary outcome of the study was defined as response rate and symptom improvement as measured by the Symptom Index of Dyspepsia, while secondary outcome was designated as improvement in quality of life (QoL) as determined by the Nepean Dyspepsia Index.</p><p><strong>Results: </strong>Symptoms of dyspepsia and QoL were improved from baseline in all groups. In EPS patients, no statistically significant differences could be observed in response rate (p = 0.239) and symptoms improvement (p = 0.344 for epigastric pain; p = 0.465 for epigastric burning). In contrast, PDS patients of the acupuncture group A showed higher response rate (53.2% vs. 19.7%, p<0.001; 53.2% vs. 35.1%, p = 0.025) and score change in postprandial fullness (1.01 vs. 0.27, p<0.001; 1.01 vs. 0.57, p<0.001), early satiation (0.81 vs. 0.21, p<0.001; 0.81 vs. 0.39, p=0.001), and QoL (14.5 vs. 4.33, p<0.001; 14.5 vs. 8.5, p<0.001) compared to the sham acupuncture and itopride group.</p><p><strong>Conclusions: </strong>FD patients with PDS responded better to the acupuncture therapies, especially at the specific acupoints along the stomach meridian. The positive therapeutic effect of acupuncture on PDS was correlated with the improvement in postprandial fullness.</p><p><strong>Trial registration: </strong>ClinicalTrial.gov NCT00599677.</p>","PeriodicalId":51049,"journal":{"name":"Forschende Komplementarmedizin","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000380983","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33342089","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Meaghan Coyle, Jingwen Deng, Anthony Lin Zhang, Jingjie Yu, Xinfeng Guo, Charlie Changli Xue, Chuanjian Lu
{"title":"Acupuncture therapies for psoriasis vulgaris: a systematic review of randomized controlled trials.","authors":"Meaghan Coyle, Jingwen Deng, Anthony Lin Zhang, Jingjie Yu, Xinfeng Guo, Charlie Changli Xue, Chuanjian Lu","doi":"10.1159/000381225","DOIUrl":"https://doi.org/10.1159/000381225","url":null,"abstract":"<p><p>The purpose of this review was to evaluate the efficacy and safety of acupuncture therapies in the treatment of psoriasis vulgaris. Embase, CENTRAL, PubMed, AMED, CINAHL, CNKI, CQVIP, CBM, and Wanfang databases were searched from inceptions to May 2013 for prospective randomized controlled trials evaluating acupuncture therapies for psoriasis vulgaris. No language limitations were applied. Studies were assessed using the Cochrane risk of bias tool. The primary outcome was Psoriasis Area Severity Index (PASI) score. Six studies (involving 522 participants) met the eligibility criteria for this review, and 5 were included in quantitative analysis. Due to the diversity of interventions, comparators and reported outcomes, meta-analysis was not possible. Results from single studies produced conflicting results for the outcomes PASI reduction, lesion reduction (non-PASI), PASI score, and relapse rate. There is some evidence of benefit of acupuncture therapies for the treatment of psoriasis vulgaris. However, the conclusions are limited by the small number of included trials and conflicting results from single studies. More research is needed to clarify the effect of acupuncture therapies for psoriasis vulgaris.</p>","PeriodicalId":51049,"journal":{"name":"Forschende Komplementarmedizin","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000381225","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33342091","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Reimbursement for Acupuncture Treatments in the German Statutory Health Insurance System].","authors":"Klaus Trinczek","doi":"10.1159/000381151","DOIUrl":"https://doi.org/10.1159/000381151","url":null,"abstract":"<p><p>Since 2007, acupuncture in Germany is reimbursed by the statutory health insurance. However, this policy is limited to the diagnoses ‘chronic pain in lumbar spine’ and ‘chronic pain in knee joint through gonarthrosis’ and connected to semi-standardized specifications for acupuncture treatment that partly do not correspond with standards in professional acupuncture training. Predominantly, acupuncture is applied in orthopedic practice. High demands in qualification and quality assurance as well as the difficulty to establish an economically attractive framework in acupuncture treatment are issues that curtail the appeal of acupuncture as treatment option to be offered by statutory health insurance.</p>","PeriodicalId":51049,"journal":{"name":"Forschende Komplementarmedizin","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000381151","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33344181","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Eri Watanabe, Kenny Kuchta, Mari Kimura, Hans Wilhelm Rauwald, Tsutomu Kamei, Jiro Imanishi
{"title":"Effects of bergamot ( Citrus bergamia (Risso) Wright & Arn.) essential oil aromatherapy on mood states, parasympathetic nervous system activity, and salivary cortisol levels in 41 healthy females.","authors":"Eri Watanabe, Kenny Kuchta, Mari Kimura, Hans Wilhelm Rauwald, Tsutomu Kamei, Jiro Imanishi","doi":"10.1159/000380989","DOIUrl":"https://doi.org/10.1159/000380989","url":null,"abstract":"<p><strong>Background: </strong>Bergamot essential oil (BEO) is commonly used against psychological stress and anxiety in aromatherapy. The primary aim of the present study was to obtain first clinical evidence for these psychological and physiological effects. A secondary aim was to achieve some fundamental understanding of the relevant pharmacological processes.</p><p><strong>Methods: </strong>Endocrinological, physiological, and psychological effects of BEO vapor inhalation on 41 healthy females were tested using a random crossover study design. Volunteers were exposed to 3 experimental setups (rest (R), rest + water vapor (RW), rest + water vapor + bergamot essential oil (RWB)) for 15 min each. Immediately after each setup, saliva samples were collected and the volunteers rested for 10 min. Subsequently, they completed the Profile of Mood States, State-Trait Anxiety Inventory, and Fatigue Self-Check List. High-frequency (HF) heart rate values, an indicator for parasympathetic nervous system activity, were calculated from heart rate variability values measured both during the 15 min of the experiment and during the subsequent 10 min of rest. Salivary cortisol (CS) levels in the saliva samples were analyzed using ELISA.</p><p><strong>Results: </strong>CS of all 3 conditions R, RW, and RWB were found to be significantly distinct (p = 0.003). In the subsequent multiple comparison test, the CS value of RWB was significantly lower when compared to the R setup. When comparing the HF values of the RWB setup during the 10 min of rest after the experiment to those of RW, this parameter was significantly increased (p = 0.026) in the RWB setup for which scores for negative emotions and fatigue were also improved.</p><p><strong>Conclusion: </strong>These results demonstrate that BEO inhaled together with water vapor exerts psychological and physiological effects in a relatively short time.</p>","PeriodicalId":51049,"journal":{"name":"Forschende Komplementarmedizin","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000380989","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33174001","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alireza Barzegar, Amir Azizi, Pouya Faridi, Abdolali Mohagheghzadeh
{"title":"Leech therapy in Iranian traditional medicine.","authors":"Alireza Barzegar, Amir Azizi, Pouya Faridi, Abdolali Mohagheghzadeh","doi":"10.1159/000377690","DOIUrl":"https://doi.org/10.1159/000377690","url":null,"abstract":"Leech therapy (LT) has a long history in medicine [1]. In Greek medicine, medicinal leech was first introduced by Hippocrates. However, the popularity of LT was reinforced by the ideas of Galen, who classified LT as an efficient procedure in medicine [2]. Nowadays, although it is not well accepted by modern medicine, LT is still used to treat venous congestion in the settings of microvascular replantation, reconstructive surgery, and traumatology [1]. On the other hand, new investigations on LT have presented its significant effect on different kinds of chronic diseases [3]. The major recommended mechanisms for LT are the anti-inflammatory, anticoagulant, analgesic, antimicrobial, and vasodilator effects as well as skin-wound healing of some enzymes, such as hirudin, calin, destabilase, bdellins, and eglins [4, 5]. In Iranian traditional medicine (ITM), LT was a common medical procedure. In Persian, the leech is called ‘Zaloo’, ‘Zard’, ‘Zardeh’ or ‘Divche’, and LT is called ‘Ersal-e-Alaq’ or ‘Zaloo Andakhtan’. It was believed that leeches drew blood from deeper sources than wet cupping [6–8]. This method is still in use by ITM practitioners and specialist physicians in ITM. In this study, we will report leeching procedures and those medical potentials which have already been used by ITM practitioners. Methods","PeriodicalId":51049,"journal":{"name":"Forschende Komplementarmedizin","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000377690","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33174002","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Miriam Ortiz, Benno Brinkhaus, Paul Enck, Frauke Musial, Frank Zimmermann-Viehoff
{"title":"Autonomic Function in Seasonal Allergic Rhinitis and Acupuncture - an Experimental Pilot Study within a Randomized Trial.","authors":"Miriam Ortiz, Benno Brinkhaus, Paul Enck, Frauke Musial, Frank Zimmermann-Viehoff","doi":"10.1159/000381086","DOIUrl":"https://doi.org/10.1159/000381086","url":null,"abstract":"<p><strong>Background: </strong>Acupuncture was shown to reduce symptoms of seasonal allergic rhinitis (SAR). The present study investigated (a) whether autonomic function would differ in SAR patients and healthy controls, and (b) whether acupuncture treatment would evoke changes in autonomic function compared to sham acupuncture.</p><p><strong>Patients and methods: </strong>SAR patients (n = 30) were recruited from a larger randomized controlled trial investigating the efficacy of acupuncture in SAR. 21 patients received acupuncture, and 9 patients received sham acupuncture. Among other we measured resting heart rate variability and cardiovascular reactivity to a cold pressure test prior to and after 12 sessions of acupuncture or sham acupuncture. In addition, 30 age- and sex-matched healthy controls were tested once.</p><p><strong>Results: </strong>SAR patients showed higher resting heart rate and lower heart rate variability as well as blunted cardiovascular responses compared to controls. After treatment, resting heart rate had decreased, and systolic blood pressure response to the cold pressure test had increased in SAR patients. We found no significant differences in autonomic function changes between patients receiving acupuncture or sham acupuncture.</p><p><strong>Conclusion: </strong>SAR patients showed alterations in autonomic function, which had partially normalized after treatment. However, in this sample we found no specific effect of acupuncture compared to sham acupuncture.</p>","PeriodicalId":51049,"journal":{"name":"Forschende Komplementarmedizin","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000381086","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33342087","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The future of complementary and integrative medicine research - international perspectives.","authors":"Claudia M Witt, Jürgen Barth, Claudia Canella","doi":"10.1159/000381512","DOIUrl":"https://doi.org/10.1159/000381512","url":null,"abstract":"rently, there are about 57,500 CAM trials from all over the world registered in the Cochrane Central Register of Controlled Trials and about 690 systematic CAM reviews in the Cochrane Database. Berman presented a few examples of systematic CAM reviews before concluding with future challenges, such as conducting reliable subgroup analyses (e.g., individual patient data meta-analysis or network meta-analysis) and systematic reviews on complex interventions as well as defining what can be considered as scientifically rigorous or relevant to real-world practice of medicine.","PeriodicalId":51049,"journal":{"name":"Forschende Komplementarmedizin","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000381512","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33344182","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Martin Schencking, Andreas Sönnichsen, Susanne Bassüner, Marcus Redaelli
{"title":"The CUPCIG (CAM-Use in Primary Care in Germany) Study:Part I-Pain. Study Protocol of a Pilot-trial to Assess Feasibility, Acceptability and Perceived Effectiveness of CAM in Pain Disorders in Primary Care.","authors":"Martin Schencking, Andreas Sönnichsen, Susanne Bassüner, Marcus Redaelli","doi":"10.1159/000430878","DOIUrl":"https://doi.org/10.1159/000430878","url":null,"abstract":"<p><strong>Background: </strong>There is limited valid data available on CAM procedures for chronic joint and neuropathic pain in primary care in Germany. Indiviual CAM qualifications of the general practitioners (GPs) and the potential of cost reduction through CAM treatment are almost unknown. The aim of this pilot trial preceding the main study is to examine the survey mode, to estimate the response rate by GPs with or without an additional qualification for CAM, and to identify the status quo in therapeutic approaches for chronic pain disorders in primary care.</p><p><strong>Methods: </strong>This is a cross-sectional study with an ex post facto design among German GPs consisting of 2 parts: In a first step, a pilot trial precedes the main study targeting 200 GPs with and 200 GPs without additional qualification in CAM in a selected region.</p><p><strong>Results: </strong>The results of the CUPCIG study comprise the distribution of pain types treated in primary care practices, the GPs' attitude toward complementary pain therapy, pharmacological or CAM treatment, the estimate of cost reduction through CAM treatment of pain, the application of diverse CAM procedures, and biographical data.</p><p><strong>Discussion: </strong>The CUPCIG study serves to compile pain therapy approaches in primary care in Germany with respect to the individual CAM expertise of the GPs.</p>","PeriodicalId":51049,"journal":{"name":"Forschende Komplementarmedizin","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000430878","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33972630","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}