Dm Disease-A-Month最新文献_第6页

C2: Editorial Board C2：编委会

IF 3.8 3区医学

Dm Disease-A-Month Pub Date : 2025-02-01 DOI: 10.1016/S0011-5029(25)00014-8

引用次数: 0

IF 3.8 3区医学

Dm Disease-A-Month Pub Date : 2025-02-01 DOI: 10.1016/S0011-5029(25)00016-1

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Foreword for Erdheim-Chester disease: Comprehensive insights from genetic mutations to clinical manifestations and therapeutic advances 厄德海姆-切斯特病前言：从基因突变到临床表现和治疗进展的综合见解。

IF 3.8 3区医学

Dm Disease-A-Month Pub Date : 2025-02-01 DOI: 10.1016/j.disamonth.2024.101846

Jerrold B. Leikin MD (Senior Editor)

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Erdheim–Chester disease: Comprehensive insights from genetic mutations to clinical manifestations and therapeutic advances 厄德海姆-切斯特病：从基因突变到临床表现和治疗进展的综合见解。

IF 3.8 3区医学

Dm Disease-A-Month Pub Date : 2025-02-01 DOI: 10.1016/j.disamonth.2024.101845

Rishabh Chaudhary MS , Anand Kumar PhD , Alpana Singh BS , Vipul Agarwal PhD , Mujeeba Rehman MS , Arjun Singh Kaushik MS , Siddhi Srivastava MS , Sukriti Srivastava MS , Vikas Mishra PhD

{"title":"Erdheim–Chester disease: Comprehensive insights from genetic mutations to clinical manifestations and therapeutic advances","authors":"Rishabh Chaudhary MS , Anand Kumar PhD , Alpana Singh BS , Vipul Agarwal PhD , Mujeeba Rehman MS , Arjun Singh Kaushik MS , Siddhi Srivastava MS , Sukriti Srivastava MS , Vikas Mishra PhD","doi":"10.1016/j.disamonth.2024.101845","DOIUrl":"10.1016/j.disamonth.2024.101845","url":null,"abstract":"<div><div>Erdheim–Chester disease (ECD) is an extremely rare non-Langerhans cell disorder that is believed to include both inflammatory and neoplastic characteristics. It is caused due to genetic mutations in proto-oncogenes like BRAF and MEK, while immunological pathways have an essential role in the onset and progression of the disease. Despite its rarity, ECD poses significant diagnostic and therapeutic challenges due to its heterogeneous clinical presentation and limited understanding of its underlying pathophysiology. Multiple organs can be affected, with the most frequent being long bones, central nervous system and retro-orbital abnormalities, pericardial and myocardial infiltration, interstitial lung disease, retroperitoneal fibrosis, and large blood vessel aberrations. Here, in this review, we comprehensively underline the current knowledge of ECD, including its epidemiology, clinical manifestations, genetics, pathophysiology, diagnostic modalities, and treatment options. By synthesizing existing literature and highlighting areas of ongoing research, this review aims to provide clinicians and researchers with a comprehensive understanding of ECD and guide future directions for improved patient care and outcomes.</div></div>","PeriodicalId":51017,"journal":{"name":"Dm Disease-A-Month","volume":"71 2","pages":"Article 101845"},"PeriodicalIF":3.8,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142933455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Title Page 标题页

IF 3.8 3区医学

Dm Disease-A-Month Pub Date : 2025-02-01 DOI: 10.1016/S0011-5029(25)00015-X

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Foreword for trafficking in the child and adolescent: Application of SAFETY and CARE for a global crisis of exploitation 前言贩卖儿童和青少年：安全和关怀在全球剥削危机中的应用。

IF 3.8 3区医学

Dm Disease-A-Month Pub Date : 2025-01-01 DOI: 10.1016/j.disamonth.2024.101826

Jerrold B. Leikin MD FACOEM, FACP, FACEP, FACMT, FAACT, FASAM (Senior Editor Disease-A-Month)

引用次数: 0

Title Page 标题页

IF 3.8 3区医学

Dm Disease-A-Month Pub Date : 2025-01-01 DOI: 10.1016/S0011-5029(25)00005-7

引用次数: 0

Trafficking in the child and adolescent: Application of SAFETY and CARE for a global crisis of exploitation 贩卖儿童和青少年：应用 "安全 "和 "关爱 "应对全球剥削危机。

IF 3.8 3区医学

Dm Disease-A-Month Pub Date : 2025-01-01 DOI: 10.1016/j.disamonth.2024.101825

Donald E. Greydanus MD, DrHC (ATHENS) , Dena Nazer MD , Artemis Tsitsika MD , Ahsan Nazeer MD , Dr Swati Y. Bhave , Elizabeth K. Greydanus LMSW, CAADC

{"title":"Trafficking in the child and adolescent: Application of SAFETY and CARE for a global crisis of exploitation","authors":"Donald E. Greydanus MD, DrHC (ATHENS) , Dena Nazer MD , Artemis Tsitsika MD , Ahsan Nazeer MD , Dr Swati Y. Bhave , Elizabeth K. Greydanus LMSW, CAADC","doi":"10.1016/j.disamonth.2024.101825","DOIUrl":"10.1016/j.disamonth.2024.101825","url":null,"abstract":"<div><div>Human trafficking in the child and adolescent is a global public health crisis that can be divided into sex trafficking, labor trafficking and organ trafficking. This discussion considers basic terminology in this area, sociodemographic information on these victims, negative effects or repercussions from such egregious actions forced on the victims, issues of screening for healthcare providers based on specific risk factors/indicators, and information regarding screening tools as well as management principles for healthcare professionals. These trafficked persons are seen in varied practice settings such as primary care offices, emergency departments, street medicine operations, and others. Clinicians can approach these victims with targeted training that encourages these pediatric persons to feel safe in healthcare settings, empowering them to help with healing (i.e., trauma-informed care). It is important that those involved in the care of trafficked victims understand the rights of these persons who are essentially hostages that need rescuing, and thus, employ a rights-based approach in dealing with these vulnerable children and youth. Culturally-sensitive concepts of prevention are considered as well to reduce this illegal, inhumane exploitation of our children and adolescents ubiquitously existing throughout the United States and the world. Indeed, there is much that clinicians and society can do to help these unfortunate minors who often feel hopeless and trapped in chaotic circumstances.</div></div>","PeriodicalId":51017,"journal":{"name":"Dm Disease-A-Month","volume":"71 1","pages":"Article 101825"},"PeriodicalIF":3.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142688752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Information for Readers 读者资讯

IF 3.8 3区医学

Dm Disease-A-Month Pub Date : 2025-01-01 DOI: 10.1016/S0011-5029(25)00006-9

引用次数: 0

C2: Editorial Board C2：编委会

IF 3.8 3区医学

Dm Disease-A-Month Pub Date : 2025-01-01 DOI: 10.1016/S0011-5029(25)00004-5

引用次数: 0