Dm Disease-A-MonthPub Date : 2024-01-01DOI: 10.1016/j.disamonth.2023.101628
Devarsh N. Shah , Harshal Prakash Chorya , N. Nishitha Ramesh , Sulochana Gnanasekaram , Neil Patel , Yashendra Sethi , Nirja Kaka
{"title":"Myopathies of endocrine origin: A review for physicians","authors":"Devarsh N. Shah , Harshal Prakash Chorya , N. Nishitha Ramesh , Sulochana Gnanasekaram , Neil Patel , Yashendra Sethi , Nirja Kaka","doi":"10.1016/j.disamonth.2023.101628","DOIUrl":"10.1016/j.disamonth.2023.101628","url":null,"abstract":"<div><p><span><span><span>Myopathies<span> are a common manifestation of endocrine disorders. Endocrine myopathies are often overlooked while considering differential diagnoses </span></span>in patients<span> with musculoskeletal symptoms. The hindrance to mobility and the musculoskeletal discomfort owing to these myopathies are important causes of disability and depreciated </span></span>quality of life in these patients. Endocrine myopathies occur due to the effects of endogenous or iatrogenic hormonal imbalance on </span>skeletal muscle<span> protein and glucose metabolism, disrupting the excitation-contraction coupling. Abnormalities of the pituitary, thyroid, parathyroid, adrenal, and gonadal hormones have all been associated with myopathies and musculoskeletal symptoms. Endocrine myopathies can either be the complication of a secondary endocrine disorder or a presenting symptom of a missed underlying disorder. Therefore, an underlying endocrine abnormality must always be excluded in all patients with musculoskeletal symptoms. This review presents a compilation of various endocrine myopathies, their etiopathogenesis, clinical presentation, diagnostic modalities, and treatment protocols.</span></p></div>","PeriodicalId":51017,"journal":{"name":"Dm Disease-A-Month","volume":"70 1","pages":"Article 101628"},"PeriodicalIF":4.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10278941","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dm Disease-A-MonthPub Date : 2024-01-01DOI: 10.1016/j.disamonth.2023.101674
Zara Manuelyan MD , Edward Butt MD, MPH , Sreeram Parupudi MD
{"title":"Gastrointestinal Behçet's disease: Manifestations, diagnosis, and management","authors":"Zara Manuelyan MD , Edward Butt MD, MPH , Sreeram Parupudi MD","doi":"10.1016/j.disamonth.2023.101674","DOIUrl":"10.1016/j.disamonth.2023.101674","url":null,"abstract":"<div><p><span><span>Behçet's disease<span> (BD) is a rare, inflammatory vascular disorder with recurrent oral and genital aphthous ulcers, along with ocular and cutaneous manifestations. Gastrointestinal (GI) BD may involve any portion of the </span></span>GI tract<span><span>. However, it is commonly described in the terminal ileum, followed by the ileocecal region. Diagnosis is challenging given lack of pathognomonic tests; therefore, it is based on clinical criteria. Management of intestinal BD includes different classes of medications including corticosteroids, 5-aminosalicylic acid, </span>immunomodulators, and anti-tumor necrosis factor alpha monoclonal antibody agents. In this review, we aim to focus on intestinal BD and provide details of clinical manifestations, diagnosis and therapeutic options of intestinal BD from </span></span>gastroenterology viewpoint.</p></div>","PeriodicalId":51017,"journal":{"name":"Dm Disease-A-Month","volume":"70 1","pages":"Article 101674"},"PeriodicalIF":4.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139375962","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dm Disease-A-MonthPub Date : 2024-01-01DOI: 10.1016/j.disamonth.2023.101672
Samina Khan MD , Sneha Annie Sebastian MD , Mihirkumar P. Parmar MBBS , Nitin Ghadge MD , Inderbir Padda MD, MPH , Ahmed S. Keshta MD , Naofel Minhaz MD , Apurva Patel MD
{"title":"Factors influencing the quality of life in inflammatory bowel disease: A comprehensive review","authors":"Samina Khan MD , Sneha Annie Sebastian MD , Mihirkumar P. Parmar MBBS , Nitin Ghadge MD , Inderbir Padda MD, MPH , Ahmed S. Keshta MD , Naofel Minhaz MD , Apurva Patel MD","doi":"10.1016/j.disamonth.2023.101672","DOIUrl":"10.1016/j.disamonth.2023.101672","url":null,"abstract":"<div><p><span><span>Inflammatory bowel disease (IBD) is a group of chronic relapsing disorders, including Crohn's disease (CD) and </span>ulcerative colitis (UC), which affects an increasing number of people worldwide. In the last few decades, the scientific world has witnessed many developments in IBD management by controlling debilitating symptoms and remaining in remission for more protracted periods. Even so, we still have a large population suffering from active IBD. An individual's </span>quality of life<span> (QoL) can be severely affected by IBD, like any other chronic illness. In this article, we have reviewed factors influencing the QoL in IBD patients, including chronic pain, diet, physical activity, and psychological factors like depression, anxiety, and stress symptoms. We also discussed the mechanisms of diet-microbial-immune system interaction, currently available dietary therapies for active CD and UC, and early psycho-social interventions that can reduce the disease burden and improve QoL in IBD patients.</span></p></div>","PeriodicalId":51017,"journal":{"name":"Dm Disease-A-Month","volume":"70 1","pages":"Article 101672"},"PeriodicalIF":4.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139027303","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dm Disease-A-MonthPub Date : 2024-01-01DOI: 10.1016/j.disamonth.2023.101673
Jerrold B. Leikin MD (Senior Editor)
{"title":"Forword for selected topics in pathology of the gastrointestinal tract","authors":"Jerrold B. Leikin MD (Senior Editor)","doi":"10.1016/j.disamonth.2023.101673","DOIUrl":"10.1016/j.disamonth.2023.101673","url":null,"abstract":"","PeriodicalId":51017,"journal":{"name":"Dm Disease-A-Month","volume":"70 1","pages":"Article 101673"},"PeriodicalIF":4.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139111337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dm Disease-A-MonthPub Date : 2024-01-01DOI: 10.1016/j.disamonth.2023.101629
Carlos Romero-Morales , Daniel López-López , Jaime Almazán-Polo , Sara Mogedano-Cruz , María Dolores Sosa-Reina , Guillermo García-Pérez-de-Sevilla , Sebastián Martín-Pérez , Ángel González-de-la-Flor
{"title":"Prevalence, diagnosis and management of musculoskeletal disorders in elite athletes: A mini-review","authors":"Carlos Romero-Morales , Daniel López-López , Jaime Almazán-Polo , Sara Mogedano-Cruz , María Dolores Sosa-Reina , Guillermo García-Pérez-de-Sevilla , Sebastián Martín-Pérez , Ángel González-de-la-Flor","doi":"10.1016/j.disamonth.2023.101629","DOIUrl":"10.1016/j.disamonth.2023.101629","url":null,"abstract":"<div><p>Musculoskeletal injuries in elite sports are ones of the most impact issue because their remarkable impact on performance caused by drastic absence of training and competition and a progressive deterioration in physical health, emotional and social athletes' dimensions. Also, the prevalence of epidemiologic research found an incidence of musculoskeletal disorders vary within sports and in elite athletes which is even higher as a consequence of higher demand physical performance. This way, the loss of physical performance due to an sport injury impacts not only the individual economic sphere of the professional but also that ofsports entities, reaching, according to some studies, a loss estimated in the range of 74.7 million pounds. Thus, the purpose of this article is to review and to provide an overview of the most common musculoskeletal injuries in elite sports precipitating factors, clinical presentation, evidence-based diagnostic evaluation, and treatment recommendations with a view to preventing medical conditions or musculoskeletal injuries that may alter performance and general health in the elite athletes.</p></div>","PeriodicalId":51017,"journal":{"name":"Dm Disease-A-Month","volume":"70 1","pages":"Article 101629"},"PeriodicalIF":4.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0011502923001098/pdfft?md5=6aa11ecdab79b39acbeb3ee5685e3750&pid=1-s2.0-S0011502923001098-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10272475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}