Dm Disease-A-MonthPub Date : 2024-05-01DOI: 10.1016/j.disamonth.2024.101711
Lisa Thompson MD , Thomas Patrianakos DO , James Garcia MD , Arshia Wadhwa MD , Ellen Yang MD , Catherine Thomas MD , Robin Schneider DO , Hudson Stern MD , Camille Palma MD , Kyle Hill , Viviana Barquet MD , Susan Anderson-Nelson MD , Kenneth McMahon , Umangi Patel MD , Quraish Ghadiali MD , Dagmara Danek DO , Brian Larsen MD , Anthony Wong MD , Sherif Dawood MD , Maxine Ludington , Michael Giovingo MD
{"title":"Autoimmune Disorders and the Eye","authors":"Lisa Thompson MD , Thomas Patrianakos DO , James Garcia MD , Arshia Wadhwa MD , Ellen Yang MD , Catherine Thomas MD , Robin Schneider DO , Hudson Stern MD , Camille Palma MD , Kyle Hill , Viviana Barquet MD , Susan Anderson-Nelson MD , Kenneth McMahon , Umangi Patel MD , Quraish Ghadiali MD , Dagmara Danek DO , Brian Larsen MD , Anthony Wong MD , Sherif Dawood MD , Maxine Ludington , Michael Giovingo MD","doi":"10.1016/j.disamonth.2024.101711","DOIUrl":"10.1016/j.disamonth.2024.101711","url":null,"abstract":"","PeriodicalId":51017,"journal":{"name":"Dm Disease-A-Month","volume":"70 5","pages":"Article 101711"},"PeriodicalIF":4.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140864123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dm Disease-A-MonthPub Date : 2024-04-01DOI: 10.1016/j.disamonth.2024.101687
Zi-Yi Choo BS , Stephanie L. Mehlis MD , Joel C. Joyce MD
{"title":"Updates in atopic dermatitis for the primary care physician: A review of advances in the understanding and treatment of atopic dermatitis","authors":"Zi-Yi Choo BS , Stephanie L. Mehlis MD , Joel C. Joyce MD","doi":"10.1016/j.disamonth.2024.101687","DOIUrl":"10.1016/j.disamonth.2024.101687","url":null,"abstract":"<div><p><span><span><span><span>Atopic dermatitis (AD) is a common inflammatory skin condition occurring in both </span>pediatric<span><span> and adult patients. Pruritus is a clinical hallmark of the disease, and patients with AD often experience disruptions to their quality of life. The pathogenesis of AD is a complex and multifactorial interplay between </span>genetic factors, epidermal barrier disruption, and </span></span>immune dysregulation<span>. Clinically, AD is characterized by pruritus, eczematous skin changes, and age-specific lesion distribution patterns. Infants and </span></span>young children<span><span><span> tend to have AD lesions on their face and extensor surfaces of their extremities while older children and adults tend to have AD lesions on flexural surfaces of their extremities. Many patients also experience a chronic and relapsing disease course. Due to the chronicity and severe pruritus, lesions often undergo secondary changes like </span>lichenification. Patients with AD can experience a number of comorbidities including other </span>atopic disease<span> (i.e. allergic rhinitis, asthma), skin infections, cardiovascular, and neuropsychiatric illnesses. Management of AD depends on the severity of the disease as well as the distribution of the disease. Traditionally, treatment of AD included the use of moisturizers / emollients, </span></span></span>topical corticosteroids<span><span><span> or topical calcineurin inhibitors, or systemic therapy with non-selective </span>immunosuppressants such as corticosteroids, </span>cyclosporine<span>, azathioprine, or similar. However, in the past decade, new biologic and small molecule drugs, both topical and systemic, have become important therapeutic options for AD patients, especially for those with moderate-to-severe disease. The development of these medications, following decades of research to better understand AD, are designed to specifically target various components of immune dysregulation and inflammation implicated in the pathogenesis of AD. Their successful development and deployment now allow for an exciting new era of treatment for individuals suffering from atopic dermatitis.</span></span></p></div>","PeriodicalId":51017,"journal":{"name":"Dm Disease-A-Month","volume":"70 4","pages":"Article 101687"},"PeriodicalIF":4.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139556796","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dm Disease-A-MonthPub Date : 2024-04-01DOI: 10.1016/j.disamonth.2024.101676
Jerrold B Leikin MD (Senior EditorDisease-A-Month)
{"title":"Foreword: Updates in atopic dermatitis for the primary care physician: A review of advances in the understanding and treatment of atopic dermatitis","authors":"Jerrold B Leikin MD (Senior EditorDisease-A-Month)","doi":"10.1016/j.disamonth.2024.101676","DOIUrl":"10.1016/j.disamonth.2024.101676","url":null,"abstract":"","PeriodicalId":51017,"journal":{"name":"Dm Disease-A-Month","volume":"70 4","pages":"Article 101676"},"PeriodicalIF":4.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139556791","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dm Disease-A-MonthPub Date : 2024-03-01DOI: 10.1016/j.disamonth.2023.101630
Jerrold B. Leikin MD (Senior EditorDisease-A-Month)
{"title":"Foreword: Health equity in pediatrics: Current concepts for the care of children in the 21st century","authors":"Jerrold B. Leikin MD (Senior EditorDisease-A-Month)","doi":"10.1016/j.disamonth.2023.101630","DOIUrl":"10.1016/j.disamonth.2023.101630","url":null,"abstract":"","PeriodicalId":51017,"journal":{"name":"Dm Disease-A-Month","volume":"70 3","pages":"Article 101630"},"PeriodicalIF":4.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10253758","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dm Disease-A-MonthPub Date : 2024-03-01DOI: 10.1016/j.disamonth.2023.101631
Cheryl A. Dickson MD, MPH , Berrin Ergun-Longmire MD , Donald E. Greydanus MD, DrHC (Athens) , Ransome Eke MD, PhD , Bethany Giedeman BS , Nikoli M. Nickson BA , Linh-Nhu Hoang MA , Uzochukwu Adabanya MD, MPH , Daniela V. Pinto Payares BS, MS , Summer Chahin PhD , Jerica McCrary BS, MPA , Katie White MA , Jin Hyung Moon BS , Nizoramo Haitova PhD , Jocelyn Deleon MD , Roger W. Apple PhD
{"title":"Health equity in pediatrics: Current concepts for the care of children in the 21st century (Dis Mon)","authors":"Cheryl A. Dickson MD, MPH , Berrin Ergun-Longmire MD , Donald E. Greydanus MD, DrHC (Athens) , Ransome Eke MD, PhD , Bethany Giedeman BS , Nikoli M. Nickson BA , Linh-Nhu Hoang MA , Uzochukwu Adabanya MD, MPH , Daniela V. Pinto Payares BS, MS , Summer Chahin PhD , Jerica McCrary BS, MPA , Katie White MA , Jin Hyung Moon BS , Nizoramo Haitova PhD , Jocelyn Deleon MD , Roger W. Apple PhD","doi":"10.1016/j.disamonth.2023.101631","DOIUrl":"10.1016/j.disamonth.2023.101631","url":null,"abstract":"<div><p><span><span>This is an analysis of important aspects of health equity in caring for children and adolescents written by a multidisciplinary team from different medical centers. In this discussion for clinicians, we look at definitions of pediatric health equity and the enormous impact of </span>social determinants of health in this area. Factors involved with pediatric healthcare disparities that are considered include race, ethnicity, gender, age, poverty, socioeconomic status, LGBT status, living in rural communities, housing instability, food insecurity, access to transportation, availability of healthcare professionals, the status of education, and employment as well as immigration. Additional issues involved with health equity in pediatrics that are reviewed will include the impact of the COVID-19 pandemic, behavioral health concepts, and the negative health effects of climate change. Recommendations that are presented include reflection of one's own attitudes on as well as an understanding of these topics, consideration of the role of various healthcare providers (i.e., </span>community health workers, peer health navigators, others), the impact of behavioral health integration, and the need for well-conceived curricula as well as multi-faceted training programs in pediatric health equity at the undergraduate and postgraduate medical education levels. Furthermore, ongoing research in pediatric health equity is needed to scrutinize current concepts and stimulate the development of ideas with an ever-greater positive influence on the health of our beloved children. Clinicians caring for children can serve as champions for the optimal health of children and their families; in addition, these healthcare professionals are uniquely positioned in their daily work to understand the drivers of health inequities and to be advocates for optimal health equity in the 21st century for all children and adolescents.</p></div>","PeriodicalId":51017,"journal":{"name":"Dm Disease-A-Month","volume":"70 3","pages":"Article 101631"},"PeriodicalIF":4.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41169044","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}