Dm Disease-A-MonthPub Date : 2024-12-01DOI: 10.1016/j.disamonth.2024.101827
Robin B. McFee DO, MPH, FACPM, FAACT
{"title":"Gastrointestinal disorders–Clinical challenges for the primary care clinician: Conclusion","authors":"Robin B. McFee DO, MPH, FACPM, FAACT","doi":"10.1016/j.disamonth.2024.101827","DOIUrl":"10.1016/j.disamonth.2024.101827","url":null,"abstract":"","PeriodicalId":51017,"journal":{"name":"Dm Disease-A-Month","volume":"70 12","pages":"Article 101827"},"PeriodicalIF":3.8,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142774150","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dm Disease-A-MonthPub Date : 2024-12-01DOI: 10.1016/j.disamonth.2024.101830
Fizza Zulfiqar MD , Muhammad Bilal MD , Yash Shah MD , Steele Morgan , Rida Fatima MD , Bryanna Singh , Sneha Annie Sebastian , Bashar Roumia , Parjanya Bhatt MD , Vinay Kumar Thallapally MD , Geetha Krishnamoorthy MD , Syed Ali Muttaqi Hussain MD
{"title":"Navigating mesenteric vasculitis: A comprehensive review of literature","authors":"Fizza Zulfiqar MD , Muhammad Bilal MD , Yash Shah MD , Steele Morgan , Rida Fatima MD , Bryanna Singh , Sneha Annie Sebastian , Bashar Roumia , Parjanya Bhatt MD , Vinay Kumar Thallapally MD , Geetha Krishnamoorthy MD , Syed Ali Muttaqi Hussain MD","doi":"10.1016/j.disamonth.2024.101830","DOIUrl":"10.1016/j.disamonth.2024.101830","url":null,"abstract":"<div><div>Vasculitides are diseases marked by inflammation of the blood vessel walls across various organ systems. The mesenteric vasculitis (MV) affects localized mesenteric vessels of the gastrointestinal tract. It usually occurs as part of a systemic inflammatory process but could also present in isolation. There are very few published reports of isolated mesenteric artery vasculitis. Presenting symptoms often include nausea, vomiting, diarrhea, abdominal pain, rectal bleeding, often complicating the diagnostic process. Diagnosing MV as the cause of abdominal pain can be challenging, and failure to diagnose can result in significant morbidity and mortality. A timely and accurate diagnosis of MV is essential for administering the appropriate immunosuppressive therapy and preventing unnecessary surgical interventions. This review aims to provide a comprehensive discussion of MV, including its clinical presentation, diagnostic approaches, and treatment options, with a focus on achieving early diagnosis to enhance outcomes and prevent complications. Furthermore, this review addresses the diagnostic challenges associated with MV, including the lack of specific criteria and symptom overlap with other gastrointestinal disorders such as atherosclerotic mesenteric ischemia, infections, malignancies, adverse medication effects, and other vessel occlusive processes. It also emphasizes the gaps in current literature regarding optimal diagnostic strategies and the necessity for standardized treatment protocols. By addressing these gaps and challenges, we aim to optimize patient care and improve prognosis for individuals affected by MV.</div></div>","PeriodicalId":51017,"journal":{"name":"Dm Disease-A-Month","volume":"70 12","pages":"Article 101830"},"PeriodicalIF":3.8,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142734314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dm Disease-A-MonthPub Date : 2024-12-01DOI: 10.1016/j.disamonth.2024.101832
R.B. McFee DO, MPH, FACPM, FAACT
{"title":"Cannabinoid Hyperemesis Syndrome (CHS) - An emerging gastrointestinal disorder and clinical challenge","authors":"R.B. McFee DO, MPH, FACPM, FAACT","doi":"10.1016/j.disamonth.2024.101832","DOIUrl":"10.1016/j.disamonth.2024.101832","url":null,"abstract":"<div><div>Nausea and vomiting are not uncommon symptoms resulting in emergency department (ED) or primary care visits. One of the emerging etiologies – Cannabinoid Hyperemesis Syndrome (CHS) remains significantly under-diagnosed, often resulting in unnecessary repeat ED visits and testing. This is in part due to lack of experience with and knowledge about CHS by health care professionals. Characterized by cyclic vomiting, often severe and intractable, it is frequently associated with a form of self-treatment; the compulsive need to take hot showers, and in the context of chronic cannabis use. With increased legalization and resultant accessibility to cannabis containing products, the risk of adverse events is significantly rising. Lack of clinical familiarity with the range of potential deleterious physical and mental health effects associated with cannabis leads to delays in appropriate diagnosis and effective treatment of CHS. Moreover, commonly utilized anti-emetics, such as ondansetron, and similar 5 HT drugs may not fully attenuate symptoms of CHS, and other interventions may be necessary; ultimately abstinence being the most effective long term clinical preventive approach. The objective of this review article is to assist the clinician in identifying the specific clinical characteristics of CHS, distinguishing it from other causes of CVS or nausea and vomiting, to facilitate more rapid, effective interventions. Collaboration with substance use professionals should also be considered during CHS treatment.</div></div>","PeriodicalId":51017,"journal":{"name":"Dm Disease-A-Month","volume":"70 12","pages":"Article 101832"},"PeriodicalIF":3.8,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142781852","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dm Disease-A-MonthPub Date : 2024-12-01DOI: 10.1016/j.disamonth.2024.101824
Michael Mallary PhD, FIEEE
{"title":"Lactose Intolerance – A practical approach, Part 2 An approach to foods","authors":"Michael Mallary PhD, FIEEE","doi":"10.1016/j.disamonth.2024.101824","DOIUrl":"10.1016/j.disamonth.2024.101824","url":null,"abstract":"","PeriodicalId":51017,"journal":{"name":"Dm Disease-A-Month","volume":"70 12","pages":"Article 101824"},"PeriodicalIF":3.8,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142774222","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dm Disease-A-MonthPub Date : 2024-12-01DOI: 10.1016/j.disamonth.2024.101823
RB McFee DO, MPH, FACPM, FAACT
{"title":"Lactose intolerance – A practical approach, Part 1","authors":"RB McFee DO, MPH, FACPM, FAACT","doi":"10.1016/j.disamonth.2024.101823","DOIUrl":"10.1016/j.disamonth.2024.101823","url":null,"abstract":"<div><div>The toxicology, immunology and gastroenterology aspects of food remain important in clinical practice, as anyone treating food related anaphylaxis, or chronic intolerance syndromes can attest. Although entire editions of journals could focus on any one aspect of adverse effects from food, the following review addresses the important and prevalent gastrointestinal condition lactose intolerance and gastrointestinal (GI) conditions that have similar presentation but require different treatment.</div></div>","PeriodicalId":51017,"journal":{"name":"Dm Disease-A-Month","volume":"70 12","pages":"Article 101823"},"PeriodicalIF":3.8,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142774292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dm Disease-A-MonthPub Date : 2024-12-01DOI: 10.1016/j.disamonth.2024.101828
Robin B. McFee DO, MPH, FACPM, FAACT
{"title":"Gastrointestinal disorders – Clinical challenges for the primary care clinician","authors":"Robin B. McFee DO, MPH, FACPM, FAACT","doi":"10.1016/j.disamonth.2024.101828","DOIUrl":"10.1016/j.disamonth.2024.101828","url":null,"abstract":"<div><div>Gastrointestinal (GI) associated symptoms are among the most common medical concerns resulting in visits to primary and specialty care. Especially challenging is the wide range of causative disorders and exposures associated with symptoms ranging from mild to life threatening - from within the GI tract as well as extra-gastrointestinal. Some of these are well described, and common, including infections, while others are newly emerging, such as cannabinoid hyperemesis syndrome. Others are well known but clinical success can remain elusive, such as food associated GI disorders - lactose intolerance and related. Although entire references have been written to address gastrointestinal diseases, in this edition of Disease a Month we will address some of the more challenging GI disorders; some of which are common but often difficult to control - food associated for example, and emerging GI illnesses such as radiation or cannabinoid hyperemesis, that lead patients to the Emergency Department, primary care clinician or specialty referral. What follows is a discussion of diverse but clinically important GI disorders, and the newer therapeutic strategies to help patients better manage their symptoms, and improve their quality of life.</div></div>","PeriodicalId":51017,"journal":{"name":"Dm Disease-A-Month","volume":"70 12","pages":"Article 101828"},"PeriodicalIF":3.8,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142774640","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}