Current Problems in Cardiology最新文献

{"title":"Corrigendum to “HIV-Related Atherosclerosis: State-of-the-Art-Review” [Current Problems in Cardiology, Volume 48, Issue 9, September 2023, 101783]","authors":"Ashot Avagimyan , Nana Pogosova , Lev Kakturskiy , Mohammad Sheibani , Olga Urazova , Artem Trofimenko , Grizelda Navarsdyan , Zinaida Jndoyan , Kristina Abgaryan , Federica Fogacci , Mattia Galli , Luciano Agati , Zhanna Kobalava , Davood Shafie , Mario Marzilli , Liana Gogiashvili , Nizal Sarrafzadegan","doi":"10.1016/j.cpcardiol.2024.102928","DOIUrl":"10.1016/j.cpcardiol.2024.102928","url":null,"abstract":"","PeriodicalId":51006,"journal":{"name":"Current Problems in Cardiology","volume":"50 2","pages":"Article 102928"},"PeriodicalIF":3.0,"publicationDate":"2024-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142720864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between polysocial risk score and CVH among women of reproductive age in the SAFE HEART study: An American Heart Association Research Goes Red Initiative","authors":"Faith E. Metlock PhD(c), RN ,&nbsp;Yaa Adoma Kwapong MD, MPH ,&nbsp;Dhananjay Vaidya M.B.B.S., Ph.D., MPH ,&nbsp;Ketum Ateh Stanislas MD, MPH ,&nbsp;Zulqarnain Javed PhD, MBBS, MPH ,&nbsp;Pamela S. Douglas MD ,&nbsp;Khurram Nasir MD MS ,&nbsp;Crystal Evans MS ,&nbsp;Roxanne Mirabal-Beltran PhD, RN ,&nbsp;Asma Rayani M.B.B.S, Sc.M ,&nbsp;Pamela Ouyang M.B.B.S., FACC, FAHA ,&nbsp;Yvonne Commodore-Mensah PhD, MHS, RN ,&nbsp;Garima Sharma MD","doi":"10.1016/j.cpcardiol.2024.102947","DOIUrl":"10.1016/j.cpcardiol.2024.102947","url":null,"abstract":"<div><h3>Background</h3><div>To assess the association between polysocial risk factors and cardiovascular health (CVH) among women of reproductive age.</div></div><div><h3>Methods</h3><div>Our cross-sectional analysis included women of reproductive age (18–44 years) from community settings and the American Heart Association's Research Goes Red (RGR) registry. Polysocial risk scores (0–14) reflected social disadvantage across domains including socioeconomic stability (education, employment, income, insurance, financial strain), living situation (housing stability, housing quality, marital status, home ownership), food security, transportation, utilities, and interpersonal safety. Suboptimal CVH was defined as having ≥2 risk factors from Life's Essential 8 metrics: physical activity, diet, body mass index, sleep, smoking, blood pressure, blood sugar, and cholesterol. Associations between polysocial risk and suboptimal CVH were analyzed using linear regression models</div></div><div><h3>Results</h3><div>Suboptimal CVH increased with higher polysocial risk, from 77.0 % in the lowest quartile to 95.2 % in the highest. Participants in quartile 3 had the highest odds of suboptimal CVH (aOR 9.52, 95 % CI 2.63–34.46), while quartile 4 showed decreased but significant odds (aOR 3.86, 95 % CI 1.03–14.40) compared to quartile 1. Hypertension (aOR 10.23, 95 % CI 3.61–29.01), diabetes (aOR 8.87, 95 % CI 3.12–25.24), hyperlipidemia (aOR 7.48, 95 % CI 2.72–20.55), and smoking (aOR 9.46, 95 % CI 3.25–27.56) were strongly associated with higher polysocial risk in community-enrolled participants, whereas trends were less consistent in RGR-enrolled participants.</div></div><div><h3>Conclusions</h3><div>Women with higher social risks face greater odds of suboptimal CVH. Screening for social determinants and tailored public health interventions are essential for mitigating CVH risks in this population.</div></div>","PeriodicalId":51006,"journal":{"name":"Current Problems in Cardiology","volume":"50 3","pages":"Article 102947"},"PeriodicalIF":3.0,"publicationDate":"2024-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142740481","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence and outcomes of concomitant cardiac amyloidosis and coronary artery disease","authors":"Koyenum Obi MD ,&nbsp;Sahil Bharwani DO MPH ,&nbsp;Vince Catalfamo MD ,&nbsp;Antonio Duran MD ,&nbsp;Harith Baldawi MD ,&nbsp;Connor Gillies DO ,&nbsp;Senthil Anand MBBS ,&nbsp;James Wever-Pinzon MD ,&nbsp;Clement Eiswirth MD ,&nbsp;Sapna Desai MD ,&nbsp;Selim Krim MD","doi":"10.1016/j.cpcardiol.2024.102932","DOIUrl":"10.1016/j.cpcardiol.2024.102932","url":null,"abstract":"<div><h3>Background</h3><div>Cardiac amyloidosis (CA) and coronary artery disease (CAD) can have similar presentations in the acute care setting which can potentially delay the diagnosis of CA.</div></div><div><h3>Methods</h3><div>We conducted a retrospective analysis of patients referred to our institution for evaluation of cardiac amyloidosis. We obtained demographic and clinical characteristics, laboratory data, and echocardiographic measurements of those patients with confirmed cardiac amyloidosis. The population was divided into two groups based on the presence of CAD. Frequency of heart failure hospitalizations, and one-year overall mortality were compared between both groups.</div></div><div><h3>Results</h3><div>Between 2018 to 2021, 327 patients with suspected cardiac amyloidosis were referred to our institution. Out of 114 confirmed CA patients, 28 patients (25%) had concomitant CAD and CA. The overall mean age of CA diagnosis was 74.7 (±8.4) years for the CAD group and 69.7 (±9.8) for the non-CAD group (P value 0.002). Notably, a higher percentage of males were observed in the CAD group (92/.9% vs. 60%, p-value 0.002), and a higher prevalence of hypertension (92.9% vs 70%, p-value 0.018) and dyslipidemia (89.3% vs 59%, p-value 0.004) were also found in the CAD group. Overall, there were no significant differences in outcomes.</div></div><div><h3>Conclusion</h3><div>Larger studies are needed to identify characteristics that will result in a prompt diagnosis of CA in patients with concomitant CAD. Although our study did not appreciate a significant difference between these two groups, outcomes of our study were likely impacted by a small sample size in the CA with CAD cohort.</div></div>","PeriodicalId":51006,"journal":{"name":"Current Problems in Cardiology","volume":"50 2","pages":"Article 102932"},"PeriodicalIF":3.0,"publicationDate":"2024-11-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142734310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Temporal trends and disparities in atherosclerosis-associated cerebrovascular disease mortality in the United States, 1999-2020","authors":"Huzaifa Ul Haq Ansari MBBS ,&nbsp;Eman Mahboob MBBS ,&nbsp;Muhammad Ammar Samad MBBS ,&nbsp;Maryam Shahzad MBBS ,&nbsp;Mushood Ahmed MBBS ,&nbsp;Syed Tabeer Hussain Naqvi MBBS ,&nbsp;Shurjeel Uddin Qazi MBBS ,&nbsp;Faizan Ahmed MD ,&nbsp;Hollie Ross-Kenny MBBS ,&nbsp;Muath Baniowda MD ,&nbsp;Hina Farrukh MD ,&nbsp;Raheel Ahmed","doi":"10.1016/j.cpcardiol.2024.102935","DOIUrl":"10.1016/j.cpcardiol.2024.102935","url":null,"abstract":"<div><h3>Background</h3><div>Cerebrovascular disease (CEVD) accounts for the second leading cause of death worldwide. Despite recent advancements in treatment strategies, the prevalence and cost associated with CEVD are rising. Atherosclerosis significantly contributes to CEVD risk by restricting cerebral blood flow, leading to ischemic stroke. This study aims to analyze trends in atherosclerosis-associated CEVD mortality in the United States from 1999 to 2020 to inform targeted prevention and management strategies.</div></div><div><h3>Methods</h3><div>We examined death certificates sourced from the CDC WONDER database, from 1999 to 2020 to identify atherosclerosis-associated CEVD mortality. Age-adjusted mortality rates (AAMRs) per 100,000 persons and annual percent changes were reported.</div></div><div><h3>Results</h3><div>A total of 325,401 deaths occurred from CEVD among adults with atherosclerosis from 1999 to 2020 in the US. The overall AAMR initially inclined from 10.9 in 1999 to 12.6 in 2001, followed by a decrease to 4.2 in 2016, and then a rise till 2020 was observed. Males had consistently higher AAMRs than females throughout the study period (Men = 11.9 vs Women = 10.1). When stratified by race, AAMRs were highest among non-Hispanic (NH) Whites (6.9), followed by NH American Indian/Alaska Native (10.9), NH Blacks/African Americans (6.6), Hispanics (4.9), and lastly by Asian/Pacific Islanders (4.2). The Western region had the highest mortality (AAMR: 7.7).</div></div><div><h3>Conclusion</h3><div>The CEVD mortality rates of adults with atherosclerosis- are increasing in the adult U.S. population. This underscores the need for increased screening, aggressive management, and subsequent surveillance of patients at risk.</div></div>","PeriodicalId":51006,"journal":{"name":"Current Problems in Cardiology","volume":"50 2","pages":"Article 102935"},"PeriodicalIF":3.0,"publicationDate":"2024-11-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142717797","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Advancements, challenges, and innovative strategies in cardiac rehabilitation for patients with acute myocardial infarction: A systematic review","authors":"Sisheng Zhang,&nbsp;Yuhui Lin","doi":"10.1016/j.cpcardiol.2024.102934","DOIUrl":"10.1016/j.cpcardiol.2024.102934","url":null,"abstract":"<div><h3>Objects</h3><div>To synthesize current evidence on the impact of cardiac rehabilitation (CR) on acute myocardial infarction (AMI) patients, explore the barriers to effective CR delivery, and evaluate the potential of innovative strategies to enhance the reach and effectiveness of CR programs.</div></div><div><h3>Methods</h3><div>This systematic review analyzed literature from 2020–2024, focusing on advancements and challenges in CR for AMI patients. A comprehensive search strategy was applied using key terms \"cardiac rehabilitation\" and \"myocardial infarction,\" encompassing a variety of study designs.</div></div><div><h3>Results</h3><div>CR significantly improves cardiovascular outcomes in AMI patients, yet faces challenges including low participation rates and adherence issues. Innovative strategies, such as home-based rehabilitation and digital health interventions, have shown potential in enhancing patient engagement and outcomes.</div></div><div><h3>Conclusion</h3><div>CR is vital for AMI recovery but requires strategies to improve participation and adherence. Future research should focus on optimizing CR strategies to better serve the heart disease patient population. Technological advancements offer promising avenues for more personalized and accessible CR programs.</div></div>","PeriodicalId":51006,"journal":{"name":"Current Problems in Cardiology","volume":"50 2","pages":"Article 102934"},"PeriodicalIF":3.0,"publicationDate":"2024-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142689588","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Linking psoriasis to atrial fibrillation: Insights from \"Association between psoriasis and atrial fibrillation: A systematic review and meta-analysis\"","authors":"Hong Zeng MD ,&nbsp;Qi Shu MBBS ,&nbsp;Jing Fang MD ,&nbsp;Hailin Du MD ,&nbsp;Ying Xue MD","doi":"10.1016/j.cpcardiol.2024.102933","DOIUrl":"10.1016/j.cpcardiol.2024.102933","url":null,"abstract":"<div><div>Patients with psoriasis indeed face an elevated risk of developing atrial fibrillation (AF), underscoring the need for vigilant monitoring to facilitate early detection and intervention. Given the current body of evidence linking psoriasis and AF is derived from observational studies, there is a clear need for more robust, multicenter, large-scale randomized studies. Such research would help to validate and reinforce the findings from observational data. Large-scale, randomized studies are necessary to confirm the association between psoriasis and AF, addressing potential biases and confounding factors present in observational research. Future studies should consider a broader range of factors that may influence the incidence of AF in psoriasis patients. This includes assessing the impact of AF \"burden,\" which could refer to the frequency, duration, or overall impact of AF episodes on patients' health. Research should delve into the role of genetic predispositions that may contribute to the development of AF in patients with psoriasis. The influence of smoking and lipid levels, among other lifestyle and environmental factors, should be examined for their potential effects on the incidence of AF in psoriasis patients. An interdisciplinary team, including dermatologists, cardiologists, and other healthcare professionals, should collaborate to provide comprehensive care for patients with psoriasis.</div></div>","PeriodicalId":51006,"journal":{"name":"Current Problems in Cardiology","volume":"50 2","pages":"Article 102933"},"PeriodicalIF":3.0,"publicationDate":"2024-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142689587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Transcatheter or surgical aortic valve replacement in high-risk patients. Insights from a third-world country","authors":"Muddassir Syed Saleem,&nbsp;Nidal Bin Kamran ,&nbsp;Hafsa Kaleem","doi":"10.1016/j.cpcardiol.2024.102936","DOIUrl":"10.1016/j.cpcardiol.2024.102936","url":null,"abstract":"","PeriodicalId":51006,"journal":{"name":"Current Problems in Cardiology","volume":"50 2","pages":"Article 102936"},"PeriodicalIF":3.0,"publicationDate":"2024-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142688506","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The enigmatic role of SIRT2 in the cardiovascular system: Deciphering its protective and detrimental actions to unlock new avenues for therapeutic intervention","authors":"Abdulaziz Hassan Alhasaniah ,&nbsp;Mohammed Alissa ,&nbsp;Fahmy Gad Elsaid ,&nbsp;Mahdi H. Alsugoor ,&nbsp;Mohammed S AlQahtani ,&nbsp;Anwer Alessa ,&nbsp;Khalid Jambi ,&nbsp;Ghadah Shukri Albakri ,&nbsp;Faisal Miqad K. Albaqami ,&nbsp;Elizabeth Bennett","doi":"10.1016/j.cpcardiol.2024.102929","DOIUrl":"10.1016/j.cpcardiol.2024.102929","url":null,"abstract":"<div><div>Cardiovascular diseases (CVDs) are leading causes of mortality throughout the world, and hence, there is a critical need to elucidate their molecular mechanisms. The Sirtuin (SIRT) family of NAD+-dependent enzymes has recently been shown to play a critical role in cardiovascular health and disease, and several SIRT isoforms, especially SIRT1 and SIRT3, have been amply investigated. However, the precise function of SIRT2 is only partially explored. Here, we review the current understanding of the involvement of SIRT2 in various cardiovascular pathologies, such as cardiac hypertrophy, ischemia-reperfusion injury, diabetic cardiomyopathy, and vascular dysfunction, with emphasis placed on the context-dependent protective or deleterious actions of SIRT2, including its wide array of catalytic activities which span beyond deacetylation. Furthermore, the review uncovers several unresolved research gaps for SIRT2 mechanisms by which SIRT2 modulates cardiac and vascular function during development and aging, thereby paving the way for the discovery of novel therapeutic targets as well as SIRT2-targeted interventions in the prevention and treatment of various cardiovascular diseases.</div></div>","PeriodicalId":51006,"journal":{"name":"Current Problems in Cardiology","volume":"50 2","pages":"Article 102929"},"PeriodicalIF":3.0,"publicationDate":"2024-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142683100","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Long-term prognosis of elderly patients undergoing atrial septal defect closure: Are we acting too late?","authors":"Maria Rita Lima ,&nbsp;Mariana Sousa Paiva ,&nbsp;Sérgio Maltês ,&nbsp;Sérgio Madeira ,&nbsp;Inês Carmo Mendes ,&nbsp;José Pedro Neves ,&nbsp;Rui Anjos","doi":"10.1016/j.cpcardiol.2024.102930","DOIUrl":"10.1016/j.cpcardiol.2024.102930","url":null,"abstract":"<div><h3>Background</h3><div>Atrial septal defects (ASD) often go unrecognized until very late in life. The impact of ASD closure on life expectancy in elderly patients remains unclear. This study compares the survival of patients≥65-years who underwent ASD closure with their average life expectancy (ALE).</div></div><div><h3>Methods</h3><div>Single-centre retrospective study including all patients ≥65-years who underwent <em>ostium secundum</em> (OS) ASD closure (surgical/percutaneous) between 1998-2020. Baseline characteristics and the predicted peri-procedural ALE (as determined per pre-defined national ALE tables) for every given patient were assessed.</div></div><div><h3>Results</h3><div>706 patients underwent OS ASD closure, 37 (5%) had ≥65 years–mean age 69±5 years, 62% presented with heart failure. Mean ASD size=21±9mm, 22% patients had severe tricuspid regurgitation, mean systolic pulmonary artery pressure (SPAP)=50±11mmHg. Five patients were treated surgically. At a mean follow-up of 9±5 years, mortality rate was 46%, occurring 8.8±5.3 years after the procedure. 25 (68%) outlived their predicted ALE. Overall, the mean age of death did not differ from the predicted ALE (79±6 vs. 84±1 years, p=0.304), however there was a 10-year absolute difference between patients who died prematurely vs. those who surpassed ALE (77±4 vs. 87±3 years, p&lt;0.001). Patients who failed to reach ALE had higher SPAP (58±10 vs. 46±8mmHg, p=0.001) and a higher incidence of severe tricuspid regurgitation (42 vs. 12%, p=0.040).</div></div><div><h3>Conclusion</h3><div>Survival after late ASD closure was comparable to the expected ALE, though one-third of the patients died prematurely. Higher SPAP and severe tricuspid regurgitation were associated with premature death. ASD closure in elderly requires a thorough evaluation to ensure maximum benefit.</div></div>","PeriodicalId":51006,"journal":{"name":"Current Problems in Cardiology","volume":"50 2","pages":"Article 102930"},"PeriodicalIF":3.0,"publicationDate":"2024-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142682872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The global magnitude and temporal trend of hypertensive heart disease burden attributable to high sodium intake from 1990 to 2021","authors":"Yuanyuan Wang ,&nbsp;Yanran Li ,&nbsp;Zhaojia Lu ,&nbsp;Zhengyan Li ,&nbsp;Rui Wang ,&nbsp;Zhengming Wang ,&nbsp;Yong Gu ,&nbsp;Liyun Chen","doi":"10.1016/j.cpcardiol.2024.102931","DOIUrl":"10.1016/j.cpcardiol.2024.102931","url":null,"abstract":"<div><h3>Background</h3><div>The relationship between high sodium intake (HSI) and hypertensive heart disease (HHD) has been confirmed. However, notable regional disparities exist in implementing effective measures to control sodium intake. This study was carried out to estimate the spatiotemporal trends in the burden of HHD attributable to HSI.</div></div><div><h3>Methods</h3><div>Data obtained from the Global Burden of Disease Study 2021 were analyzed, considering factors such as age, gender, year, and region. Joinpoint regression analysis was applied to investigate the temporal trends in the HHD burden resulting from HSI over the past 32 years.</div></div><div><h3>Results</h3><div>From 1990 to 2021, the global cases of HHD increased significantly annually. The age-standardized prevalence rates showed a slow gradual increase. However, both the age-standardized death and disability-adjusted life-year (DALY) rates decreased. Specifically, HSI was responsible for 29.2% of total HHD deaths and 30.4% of total DALYs in 1990 but only 22.8% of total HHD deaths and 23.4% of total DALYs in 2021. A greater burden from HSI exposure was observed among men, older adults and people living in middle and low sociodemographic index (SDI) countries and regions. Moreover, over the 32-year period, Guam and Colombia demonstrated the highest reduction in age-standardized death and DALY rates, respectively.</div></div><div><h3>Conclusion</h3><div>Globally, the age-standardized burden of HHD due to HSI has demonstrated a decline. Although some areas have effectively managed this issue, it remains a challenge in specific areas. Hence, it is crucial to examine and implement the strategies adopted by successful nations to further mitigate this burden.</div></div>","PeriodicalId":51006,"journal":{"name":"Current Problems in Cardiology","volume":"50 2","pages":"Article 102931"},"PeriodicalIF":3.0,"publicationDate":"2024-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142683183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}