Annales De Pathologie最新文献

{"title":"[Foetal paraspinal neuroblastoma: A case report of autopsy findings].","authors":"O H Fadli, M T Arasceli","doi":"10.1016/j.annpat.2024.12.005","DOIUrl":"https://doi.org/10.1016/j.annpat.2024.12.005","url":null,"abstract":"<p><p>Neuroblastoma is a rare tumour originating from neural crest cells, primarily occurring in the adrenal glands and sympathetic ganglia, with prenatal diagnosis often complicated by the difficulty in distinguishing it from other foetal abdominal or paraspinal masses. We present a case of foetal neuroblastoma in a 26-year old woman who, at 36 weeks of gestation, experienced absent foetal movements, leading to ultrasound confirmation of foetal demise with associated effusions. An emergency caesarean section revealed a stillborn male foetus with a previously undetected encapsulated mass in the posterior mediastinum, which was confirmed as neuroblastoma through histopathological analysis. This case highlights the challenges in prenatal diagnosis, as the tumour went unnoticed despite routine imaging. It contributes to the limited literature on foetal neuroblastoma, underscoring the need for further research on effective management strategies.</p>","PeriodicalId":50969,"journal":{"name":"Annales De Pathologie","volume":" ","pages":""},"PeriodicalIF":0.5,"publicationDate":"2024-12-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142900050","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corrélations cytologie - histologie en pathologie urothéliale. Introduction.","authors":"Sophie Ferlicot, Monique Courtade-Saïdi","doi":"10.1016/j.annpat.2024.11.003","DOIUrl":"https://doi.org/10.1016/j.annpat.2024.11.003","url":null,"abstract":"","PeriodicalId":50969,"journal":{"name":"Annales De Pathologie","volume":" ","pages":""},"PeriodicalIF":0.5,"publicationDate":"2024-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142820112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[An astonishing diagnosis!]","authors":"Dong-Min Yoe, Aurélien Morini","doi":"10.1016/j.annpat.2024.11.002","DOIUrl":"https://doi.org/10.1016/j.annpat.2024.11.002","url":null,"abstract":"","PeriodicalId":50969,"journal":{"name":"Annales De Pathologie","volume":" ","pages":""},"PeriodicalIF":0.5,"publicationDate":"2024-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142820108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Accreditation in anatomic pathology].","authors":"Mathilde Gonzalez, Magali Demeules, Pierre-Alain Thiebaut, Agathe Baudrier, Jean-Christophe Sabourin, Nicolas Piton","doi":"10.1016/j.annpat.2024.10.005","DOIUrl":"https://doi.org/10.1016/j.annpat.2024.10.005","url":null,"abstract":"<p><p>The purpose of this article is to provide a simple explanation of the accreditation process applied to the field of pathology. After defining some basic notions in the field of quality in health, and then detailing the accreditation process in general, we focus on the specific field of pathology with the implementation of the quality management system, the validation or verification of the methods and then the audit of the structure by the French committee for accreditation COFRAC. We end with some general considerations, insisting on the benefits brought by the entry of a structure into this accreditation process.</p>","PeriodicalId":50969,"journal":{"name":"Annales De Pathologie","volume":" ","pages":""},"PeriodicalIF":0.5,"publicationDate":"2024-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142787745","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[An adult presenting with an infantile retroperitoneal tumour].","authors":"Lakhdar Khellaf, Sébastien Carrère, Diego Tosi, Stéphanie Nougaret, Pierre Gemival","doi":"10.1016/j.annpat.2024.10.002","DOIUrl":"https://doi.org/10.1016/j.annpat.2024.10.002","url":null,"abstract":"","PeriodicalId":50969,"journal":{"name":"Annales De Pathologie","volume":" ","pages":""},"PeriodicalIF":0.5,"publicationDate":"2024-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142781850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Hepatocellular carcinoma: Histological and molecular classifications].","authors":"Aurélie Beaufrère, Valérie Paradis","doi":"10.1016/j.annpat.2024.10.004","DOIUrl":"https://doi.org/10.1016/j.annpat.2024.10.004","url":null,"abstract":"<p><p>Hepatocellular carcinoma (HCC) is the most common primary malignant liver tumour, with a poor prognosis, ranking third for cancer mortality worldwide. HCC is a morphologically and molecularly heterogeneous tumour. This update aims to address this heterogeneity by describing the different histological and molecular subtypes of HCC. Morphologically, eight subtypes have been described according to the WHO classification: steatohepatitic, macrotrabecular massive (MTM), clear cell, chromophobe, scirrhous, fibrolamellar, lymphocyte-rich and neutrophil-rich. Other HCCs are classified as non-specific (not otherwise specified or NOS). These subtypes may be associated with a different prognosis, particularly the MTM, which displays a poorer survival than the other subtypes. Genomically, most HCCs present mutations in the TERT promoter, while other mutations occured later in carcinogenesis, such as TP53 and CTNNB1. TP53 mutated HCCs are associated with a poor prognosis and the MTM subtype. From a transcriptomic standpoint, two classifications are particularly noteworthy, as they are associated with both prognosis (proliferative vs. non-proliferative classification) and clinical, morphological and genomic tumour characteristics (G1-G6 classification). In conclusion, the morphological heterogeneity of HCC, directly linked to molecular heterogeneity, is associated with prognosis. This strongly supports the specification of the different HCC subtypes in our reports.</p>","PeriodicalId":50969,"journal":{"name":"Annales De Pathologie","volume":" ","pages":""},"PeriodicalIF":0.5,"publicationDate":"2024-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142689542","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Leçons sur les réactions aux produits de comblement à visée esthétique","authors":"Françoise Plantier","doi":"10.1016/j.annpat.2024.09.005","DOIUrl":"10.1016/j.annpat.2024.09.005","url":null,"abstract":"<div><div>Tout produit injecté pour comblement des rides peut se comporter comme un corps étranger et provoquer des réactions granulomateuses inesthétiques. Le sujet est en constante évolution, soumis aux aléas du marché. L’acide hyaluronique est le plus injecté car résorbable et probablement le moins « toxique ». En cas de développement d’une sarcoïdose ou d’un trouble immunitaire, et en cas de vaccination contre la Covid, des granulomes peuvent se développer même en cas d’injections très anciennes.</div></div><div><div>Any product injected to fill wrinkles can behave like a foreign body and cause unsightly granulomatous reactions. The subject is constantly evolving, subject to the vagaries of the market. Hyaluronic acid is the most injected product because it is resorbable and probably the least “toxic”. In the event of sarcoidosis or an immune disorder, and in the event of vaccination against Covid, granulomas can develop even after very old injections.</div></div>","PeriodicalId":50969,"journal":{"name":"Annales De Pathologie","volume":"44 6","pages":"Pages 491-497"},"PeriodicalIF":0.5,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142480061","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Éditorial","authors":"Pr Audrey Rousseau","doi":"10.1016/j.annpat.2024.10.001","DOIUrl":"10.1016/j.annpat.2024.10.001","url":null,"abstract":"","PeriodicalId":50969,"journal":{"name":"Annales De Pathologie","volume":"44 6","pages":"Page 395"},"PeriodicalIF":0.5,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142512466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Angiopathie amyloïde cérébroméningée","authors":"Thibaut Wolf ,&nbsp;Agathe Chammas ,&nbsp;Béatrice Lannes ,&nbsp;Benoît Lhermitte","doi":"10.1016/j.annpat.2024.09.008","DOIUrl":"10.1016/j.annpat.2024.09.008","url":null,"abstract":"<div><div>L’angiopathie amyloïde représente 20 % des causes d’hématome intra-parenchymateux. L’examen histopathologique doit rechercher attentivement les anomalies vasculaires caractéristiques et l’examen immunohistochimique avec un anticorps anti-peptide βA4 doit être réalisé de façon systématique. En pratique, les produits d’évacuation d’un hématome intracérébral doivent être inclus en totalité, car les lésions peuvent être focales. L’existence d’antécédents neurochirurgicaux peut faire suggérer une étiologie iatrogène chez les patients de moins de 55 ans.</div></div><div><div>Amyloid angiopathy represents 20% of causes of intraparenchymal hematoma. The histopathological examination must carefully look for characteristic vascular abnormalities and the immunohistochemistry for the βA4 peptide must be carried out systematically. In practice, the evacuation products of an intracerebral hematoma must be fully included, because the lesions may be focal. The existence of a neurosurgical history may suggest an iatrogenic etiology when patients are less than 55 years-old.</div></div>","PeriodicalId":50969,"journal":{"name":"Annales De Pathologie","volume":"44 6","pages":"Pages 486-490"},"PeriodicalIF":0.5,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142367331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Carcinome à cellules hautes et à polarité inversée du sein : à propos d’un cas","authors":"","doi":"10.1016/j.annpat.2024.01.001","DOIUrl":"10.1016/j.annpat.2024.01.001","url":null,"abstract":"&lt;div&gt;&lt;div&gt;Le carcinome à cellules hautes et à polarité inversée du sein, anciennement dénommé « carcinome papillaire solide à polarité inversée » est une entité rare, récemment introduite dans la dernière édition de la classification OMS des tumeurs du sein. Il s’agit d’une tumeur de phénotype triple négatif et de diagnostic difficile. Bien que peu de cas ont été rapportés dans la littérature, la connaissance de cette tumeur mammaire est essentielle afin de la distinguer des autres carcinomes triples négatifs, de moins bon pronostic. Nous rapportons un cas de carcinome à cellules hautes et à polarité inversée du sein chez une patiente âgée de 43 ans, sans antécédents néoplasiques mammaires ni masse palpable à l’examen clinique. La tumeur a été découverte sur une écho-mammographie de dépistage qui a révélé une lésion classée ACR 4b. Une microbiopsie de cette lésion a conclu à une prolifération papillaire dont l’exérèse était souhaitable. Une tumorectomie a été réalisée. Les études anatomopathologique et immunohistochimique de la pièce opératoire ont confirmé le diagnostic de carcinome à cellules hautes et à polarité inversée exprimant la calrétinine et l’IDH1. Vu la rareté de cette entité, il n’existe pas de standard thérapeutique. Dans notre cas, une mastectomie sans curage ganglionnaire a été réalisée. Le bilan d’extension était négatif et la patiente n’a pas reçu de traitement adjuvant. Après un recul clinique de 12 mois, aucune récidive n’a été notée. À travers cette observation, nous précisons les caractéristiques histopathologiques, immunohistochimiques et moléculaires de cette entité rare.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;div&gt;Reverse polarity high-cell carcinoma of the breast, formerly known as reverse polarity solid papillary carcinoma, is a rare entity recently introduced into the latest edition of the WHO classification of breast tumors. Its phenotype is triple-negative, and its diagnosis difficult. Although few cases have been reported in the literature, knowledge of this breast tumor is essential to distinguish it from other triple-negative carcinomas, which have a poorer prognosis. We report a case of high-cell, inverted-polarity carcinoma of the breast in a 43-year-old female patient with no history of breast neoplasia and no palpable mass on clinical examination. The tumour was discovered following a screening echomammogram, which revealed a lesion classified ACR 4b. A microbiopsy of this lesion concluded that it was a papillary proliferation that should be removed. A lumpectomy was performed. Histopathological and immunohistochemical studies of the surgical specimen confirmed the diagnosis of high-cell, reverse-polarity carcinoma expressing calretinin and IDH1. Given the rarity of this entity, there is no standard treatment. In our case, a mastectomy without lymph node curage was performed. The extension work-up was negative and the patient received no adjuvant treatment. After 12 months, the patient is in complete remission. In this case report, ","PeriodicalId":50969,"journal":{"name":"Annales De Pathologie","volume":"44 6","pages":"Pages 505-509"},"PeriodicalIF":0.5,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139564972","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}