Academic Radiology最新文献

{"title":"The Impact of Sleep Disorders on Glymphatic Function in Parkinson's Disease Using Diffusion Tensor MRI.","authors":"Yuting Li, Teng Zhang, Chao Wang, Leiyu Geng, Tingting Liu, Tong Lu, Shenghong Ju","doi":"10.1016/j.acra.2024.11.030","DOIUrl":"https://doi.org/10.1016/j.acra.2024.11.030","url":null,"abstract":"<p><strong>Rationale and objectives: </strong>To investigate the impact of sleep disorders on glymphatic system in Parkinson's disease (PD) using a non-invasive imaging technique called diffusion tensor image analysis along perivascular space (DTI-ALPS).</p><p><strong>Materials and methods: </strong>A total of 114 PD patients and 54 healthy controls (HCs) underwent sleep questionnaires and MRI examinations as part of data collection from the Parkinson's Progression Markers Initiative cohort. An automated pipeline was proposed for ALPS calculation to reduce biases from manually region delineation. ALPS indices were compared between PD and HCs, as well as between PD with and without sleep disorders. Correlation was assessed between ALPS index and clinical characteristics. Furthermore, a 2-year follow-up analysis was performed to explore longitudinal impact of sleep disorders on glymphatic function.</p><p><strong>Results: </strong>PD patients showed significantly decreased ALPS indices compared with HCs (P = 0.038). PD patients with sleep disorders showed slightly but not significantly decreased ALPS index compared with those with normal sleep (P = 0.058). However, PD patients who transitioned from normal sleep to sleep disorders showed significantly decreased ALPS index at follow-up compared to baseline (P = 0.047). In contrast, patients who maintained normal sleep showed no significant difference in ALPS index between follow-up and baseline (P = 0.934). In addition, PD patients who transitioned from normal sleep to sleep disorders showed significantly increased ΔMDS-UPDRS Part I score (P = 0.004), ΔMDS-UPDRS total score (P = 0.040) and ΔSCOPA-AUT (P = 0.048) compared with PD who remained normal sleep.</p><p><strong>Conclusion: </strong>Sleep disorders accelerate dysfunction of glymphatic system as indicated by ALPS index in PD patients, which may be associated with symptom progression in follow-up analysis. Therefore, more attention should be devoted to prevent sleep disorders in early PD.</p>","PeriodicalId":50928,"journal":{"name":"Academic Radiology","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2024-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142774408","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"RE: “A Comparative Review of Imaging Journal Policies for Use of AI in Manuscript Generation”","authors":"Hinpetch Daungsupawong ,&nbsp;Viroj Wiwanitkit","doi":"10.1016/j.acra.2024.06.017","DOIUrl":"10.1016/j.acra.2024.06.017","url":null,"abstract":"","PeriodicalId":50928,"journal":{"name":"Academic Radiology","volume":"31 12","pages":"Page 5341"},"PeriodicalIF":3.8,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141602122","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Radiology, Hardship, and the Call to Service","authors":"Richard B. Gunderman MD PhD","doi":"10.1016/j.acra.2024.09.062","DOIUrl":"10.1016/j.acra.2024.09.062","url":null,"abstract":"","PeriodicalId":50928,"journal":{"name":"Academic Radiology","volume":"31 12","pages":"Pages 5337-5338"},"PeriodicalIF":3.8,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142407178","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinically Available and Reproducible Prediction Models for IDH and CDKN2A/B Gene Status in Adult-type Diffuse Gliomas","authors":"MeiLin Zhu ,&nbsp;Fang Han ,&nbsp;JiaHao Gao ,&nbsp;Jing Yang ,&nbsp;LongLin Yin ,&nbsp;ZunGuo Du ,&nbsp;JiaWen Zhang","doi":"10.1016/j.acra.2024.06.020","DOIUrl":"10.1016/j.acra.2024.06.020","url":null,"abstract":"<div><h3>Purpose</h3><div>Isocitrate dehydrogenase<span> (IDH) and cyclin-dependent kinase inhibitor (CDKN) 2A/B status holds important prognostic value in diffuse gliomas. We aimed to construct prediction models using clinically available and reproducible characteristics for predicting IDH-mutant and CDKN2A/B homozygous deletion in adult-type diffuse glioma patients.</span></div></div><div><h3>Materials and Methods</h3><div>This retrospective, two-center study analysed 272 patients with adult-type diffuse glioma (230 for primary cohort and 42 for external validation cohort). Two radiologists independently assessed the patients’ images according to the Visually AcceSAble Rembrandt Images (VASARI) feature set. Least absolute shrinkage and selection operator (LASSO) regression analysis was used to optimise variable selection. Multivariable logistic regression analysis<span> was used to develop the prediction models. Calibration plots, receiver operating characteristic (ROC) curves, and decision curve analysis (DCA) were used to validate the models. Nomograms were developed visually based on the prediction models.</span></div></div><div><h3>Results</h3><div>The interobserver agreement between the two radiologists for VASARI features was excellent (κ range, 0.813–1). For the IDH-mutant prediction model, the area under the curves (AUCs) was 0.88–0.96 in the internal and external validation sets, For the CDKN2A/B homozygous deletion model, the AUCs were 0.80–0.86 in the internal and external validation sets. The decision curves show that both prediction models had good net benefits.</div></div><div><h3>Conclusion</h3><div>The prediction models which basing on VASARI and clinical features provided a reliable and clinically meaningful preoperative prediction for IDH and CDKN2A/B status in diffuse glioma patients. These findings provide a foundation for precise preoperative non-invasive diagnosis and personalised treatment approaches for adult-type diffuse glioma patients.</div></div>","PeriodicalId":50928,"journal":{"name":"Academic Radiology","volume":"31 12","pages":"Pages 5164-5174"},"PeriodicalIF":3.8,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141472239","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Combined Quantitative amyloid-β PET and Structural MRI Features Improve Alzheimer’s Disease Classification in Random Forest Model - A Multicenter Study","authors":"Yi-Wen Bao ,&nbsp;Zuo-Jun Wang ,&nbsp;Yat-Fung Shea ,&nbsp;Patrick Ka-Chun Chiu ,&nbsp;Joseph SK Kwan ,&nbsp;Felix Hon-Wai Chan ,&nbsp;Henry Ka-Fung Mak","doi":"10.1016/j.acra.2024.06.040","DOIUrl":"10.1016/j.acra.2024.06.040","url":null,"abstract":"<div><h3>Rationale and Objectives</h3><div>Prior to clinical presentations of Alzheimer’s Disease (AD), neuropathological changes, such as amyloid-β and brain atrophy, have accumulated at the earlier stages of the disease. The combination of such biomarkers assessed by multiple modalities commonly improves the likelihood of AD etiology. We aimed to explore the discriminative ability of Aβ PET features and whether combining Aβ PET and structural MRI features can improve the classification performance of the machine learning model in older healthy control (OHC) and mild cognitive impairment (MCI) from AD.</div></div><div><h3>Material and methods</h3><div>We collected 94 AD patients, 82 MCI patients, and 85 OHC from three different cohorts. 17 global/regional Aβ features in Centiloid, 122 regional volume, and 68 regional cortical thickness were extracted as imaging features. Single or combined modality features were used to train the random forest model on the testing set. The top 10 features were sorted based on the Gini index in each binary classification.</div></div><div><h3>Results</h3><div>The results showed that AUC scores were 0.81/0.86 and 0.69/0.68 using sMRI/Aβ PET features on the testing set in differentiating OHC and MCI from AD. The performance was improved while combining two-modality features with an AUC of 0.89 and an AUC of 0.71 in two classifications. Compared to sMRI features, particular Aβ PET features contributed more to differentiating AD from others.</div></div><div><h3>Conclusion</h3><div>Our study demonstrated the discriminative ability of Aβ PET features in differentiating AD from OHC and MCI. A combination of Aβ PET and structural MRI features can improve the RF model performance.</div></div>","PeriodicalId":50928,"journal":{"name":"Academic Radiology","volume":"31 12","pages":"Pages 5154-5163"},"PeriodicalIF":3.8,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141604493","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prospective Comparison of 2D and 3D T2-Weighted Imaging in Multiparametric MRI for Assessing Muscle Invasion Accuracy Using VI-RADS in Bladder Cancer","authors":"Xinxin Zhang MD ,&nbsp;Yichen Wang MD ,&nbsp;Xiaojuan Xu MD ,&nbsp;Mancang Hu MD ,&nbsp;Sicong Wang PhD ,&nbsp;Yan Chen MD ,&nbsp;Xinming Zhao MD","doi":"10.1016/j.acra.2024.07.002","DOIUrl":"10.1016/j.acra.2024.07.002","url":null,"abstract":"<div><h3>Rationale and Objectives</h3><div><span>T2-weighted imaging (T2WI) is an essential sequence for assessing the staging of bladder cancer. This study aimed to compare the image quality and </span>diagnostic performance<span> of three-dimensional (3D) and two-dimensional (2D) T2WI in diagnosing muscle invasion of bladder cancer using Vesical Imaging Reporting and Data System (VI-RADS).</span></div></div><div><h3>Materials and Methods</h3><div>Between August 2022 and May 2023, 101 participants with bladder cancer underwent multiparametric MRI including 3D and 2D T2WI. Two radiologists independently reviewed 2D and 3D T2WI, evaluating image quality and muscle invasion based on VI-RADS scoring. The paired Wilcoxon signed-rank test assessed the differences between 2D and 3D T2WI. The areas under the receiver operating characteristic curve (AUCs) were utilized to compare the diagnostic performance.</div></div><div><h3>Results</h3><div>3D T2WI demonstrated significantly superior overall image quality scores with less artifacts than 2D T2WI. Compared to 2D T2WI, 3D T2WI categories had significantly higher AUC for both readers (reader 1: 0.937 vs. 0.909, <em>p</em> = .02; reader 2: 0.923 vs.0.884, <em>p</em> = .04). The VI-RADS score of 3D MR protocol had higher accuracy than 2D MR protocol (reader 1: 0.931 vs. 0.921, <em>p</em> = .02; reader 2: 0.931 vs. 0.911, <em>p</em> = .02). However, there were no significant differences in AUC values of VI-RADS categories between 2D and 3D MR protocol (all <em>p</em> &gt; 0.05).</div></div><div><h3>Conclusion</h3><div>In assessing muscle invasion of bladder cancer, 3D T2WI exhibited superior overall image quality and diagnostic performance than 2D T2WI. However, 3D T2WI did not significantly improve the diagnostic performance of VI-RADS.</div></div>","PeriodicalId":50928,"journal":{"name":"Academic Radiology","volume":"31 12","pages":"Pages 5034-5041"},"PeriodicalIF":3.8,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141753290","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lipiodol Combined with Drug-eluting Beads Versus Drug-eluting Beads Alone for Transarterial Chemoembolization of Hepatocellular carcinoma: A Multicenter Study","authors":"Kun Ji ,&nbsp;Yang Shi ,&nbsp;Zhiying Liang ,&nbsp;Cong Zhang ,&nbsp;Li Jing ,&nbsp;Tiantian Xu ,&nbsp;Shoujin Cao ,&nbsp;Guanhui Zhou ,&nbsp;Yunbo Cao ,&nbsp;Jiahua Niu ,&nbsp;Jinghua Zhu ,&nbsp;Jing Ai ,&nbsp;Zhen Li ,&nbsp;Feng Chen","doi":"10.1016/j.acra.2024.05.033","DOIUrl":"10.1016/j.acra.2024.05.033","url":null,"abstract":"<div><h3>Rationale and Objectives</h3><div>This study aimed to propose a novel approach of lipiodol<span><span> combined with drug-eluting beads transarterial chemoembolization (Lipiodol-DEB TACE) and to compare the safety and efficacy with DEB-TACE alone for patients with unresectable </span>hepatocellular carcinoma (HCC).</span></div></div><div><h3>Materials and Methods</h3><div><span>From the database of four centers, the records of patients with HCC who received DEB-TACE or Lipiodol-DEB TACE as initial treatment were retrospectively evaluated. The tumor response was measured based on the Modified Response Evaluation Criteria in Solid Tumors. </span>Overall survival<span> (OS), progression-free survival (PFS) and adverse events (AEs) were compared between two groups.</span></div></div><div><h3>Results</h3><div>A total of 244 patients were included with 160 patients receiving DEB-TACE and 84 patients receiving Lipiodol-DEB TACE. Lipiodol-DEB TACE group had higher objective response rate (86.9 % vs. 76.3 %), higher disease control rate (97.6 % vs. 88.8 %), longer median OS (42.6 vs. 25.8 months) and longer median PFS (34.0 vs. 17.0 months) than DEB-TACE group (<em>P</em><span><span> &lt; 0.05). There was no significant difference observed in the incidence of AEs between two groups. Cox analysis identified total bilirubin level, maximum tumor diameter, TACE method and </span>portal vein<span> invasion as independent prognostic factors.</span></span></div></div><div><h3>Conclusion</h3><div>Lipiodol-DEB TACE was a safe option and associated with improved tumor response and survival outcome compared to DEB-TACE alone for selected patients with HCC.</div></div>","PeriodicalId":50928,"journal":{"name":"Academic Radiology","volume":"31 12","pages":"Pages 4912-4922"},"PeriodicalIF":3.8,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141312212","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Delta-radiomics Analysis Based on Multi-phase Contrast-enhanced MRI to Predict Early Recurrence in Hepatocellular Carcinoma After Percutaneous Thermal Ablation","authors":"Wanrong Huang MD ,&nbsp;Yifan Pan ,&nbsp;Huifang Wang MD ,&nbsp;Lu Jiang ,&nbsp;Yamei Liu ,&nbsp;Shunli Wang ,&nbsp;Hanting Dai MD ,&nbsp;Rongping Ye MD ,&nbsp;Chuan Yan MD ,&nbsp;Yueming Li MD, PhD","doi":"10.1016/j.acra.2024.06.002","DOIUrl":"10.1016/j.acra.2024.06.002","url":null,"abstract":"<div><h3>Rationale and Objectives</h3><div>It is critical to predict early recurrence (ER) after percutaneous thermal ablation (PTA) for hepatocellular carcinoma (HCC). We aimed to develop and validate a delta-radiomics nomogram based on multi-phase contrast-enhanced magnetic resonance imaging (MRI) to preoperatively predict ER of HCC after PTA.</div></div><div><h3>Materials and Methods</h3><div>We retrospectively enrolled 164 patients with HCC and divided them into training, temporal validation, and other-scanner validation cohorts (n = 110, 29, and 25, respectively). The volumes of interest of the intratumoral and/or peritumoral regions were delineated on preoperative multi-phase MR images. Original radiomics features were extracted from each phase, and delta-radiomics features were calculated. Logistic regression was used to train the corresponding radiomics models. The clinical and radiological characteristics were evaluated and combined to establish a clinical-radiological model. A fusion model comprising the best radiomics scores and clinical-radiological risk factors was constructed and presented as a nomogram. The performance of each model was evaluated and recurrence-free survival (RFS) was assessed.</div></div><div><h3>Results</h3><div>Child-Pugh grade B, high-risk tumor location, and an incomplete/absent tumor capsule were independent predictors of ER. The optimal radiomics model comprised 12 delta-radiomics features with areas under the curve (AUCs) of 0.834, 0.795, and 0.769 in the training, temporal validation, and other-scanner validation cohorts, respectively. The nomogram showed the best predictive performance with AUCs as 0.893, 0.854, and 0.827 in the three datasets. There was a statistically significant difference in RFS between the risk groups calculated using the delta-radiomics model and nomogram.</div></div><div><h3>Conclusions</h3><div>The nomogram combined with the delta-radiomic score and clinical-radiological risk factors could non-invasively predict ER of HCC after PTA.</div></div>","PeriodicalId":50928,"journal":{"name":"Academic Radiology","volume":"31 12","pages":"Pages 4934-4945"},"PeriodicalIF":3.8,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141433204","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Incremental Value of Native T1 Mapping-Derived Radiomics for The Diagnosis of Amyloid Light-Chain Cardiac Amyloidosis","authors":"Quanmei Ma ,&nbsp;Jiayu Chen ,&nbsp;Liqi Cao ,&nbsp;Xinyi Wu ,&nbsp;Zekun Tan ,&nbsp;Hui Liu","doi":"10.1016/j.acra.2024.07.005","DOIUrl":"10.1016/j.acra.2024.07.005","url":null,"abstract":"<div><h3>Rationale and Objectives</h3><div>This study aimed to assess the incremental diagnostic value of non-contrast T1 mapping-derived radiomics in patients with amyloid light-chain cardiac amyloidosis (AL-CA).</div></div><div><h3>Methods</h3><div>We retrospectively collected 86 patients with suspected AL-CA and 28 control patients who underwent cardiac MRI at 3.0 T in our institution, and the MRI data were divided into a training set and a test set. Radiomic features were extracted based on native T1 maps using a freely available software package. We applied LASSO logistic regression method to select radiomic features with high diagnostic value of AL-CA and develop a predictive model. The diagnostic performance of the radiomics model was evaluated using receiver operating characteristic curve analysis and compared to T1 values.</div></div><div><h3>Results</h3><div>A total of 70 people were diagnosed with AL-CA, and cardiac involvement was observed in 202 myocardial slicers. The accuracy of T1 values for the diagnosis of myocardial involvement was 0.886, with a threshold value of 1375 ms. The radiomics score comprised a total of three features. The radiomics score demonstrated significantly higher sensitivity in detecting myocardial involvement compared to T1 values in both the training set (AUC 0.886 vs. 0.924, <em>P</em> = 0.025) and the test set (0.862 vs 0.915, <em>P</em> = 0.026). The combined model comprising T1 values and a radiomic feature named S(4,−4) Correlat showed higher diagnostic performance in comparison to T1 values alone both in the training and test sets, with AUC values of 0.929 and 0.909, respectively.</div></div><div><h3>Conclusion</h3><div>The radiomic features derived from native T1 mapping demonstrated incremental value for the diagnosis of AL-CA, which may be an alternative to T1-derived ECV to avoid the use of contrast in patients with suspected myocardial involvement in systemic amyloidosis.</div></div>","PeriodicalId":50928,"journal":{"name":"Academic Radiology","volume":"31 12","pages":"Pages 4801-4810"},"PeriodicalIF":3.8,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141898893","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Low-dose Ultra-high-resolution Photon-Counting Detector CT for Visceral Artery CT Angiography: A Preliminary Study","authors":"Lingyun Wang ,&nbsp;Yangfan Hu ,&nbsp;Jingyu Zhong ,&nbsp;Xing Yue ,&nbsp;Zhihan Xu ,&nbsp;Bei Ding ,&nbsp;Jingshen Chu ,&nbsp;Fuhua Yan ,&nbsp;Weiwu Yao ,&nbsp;Huan Zhang ,&nbsp;Weiguo Hu","doi":"10.1016/j.acra.2024.06.044","DOIUrl":"10.1016/j.acra.2024.06.044","url":null,"abstract":"<div><h3>Rationale and Objectives</h3><div>To validate the image quality of low-dose ultra-high-resolution (UHR) scanning mode of photon-counting detector CT (PCD-CT) for visceral artery computed tomography angiography (CTA).</div></div><div><h3>Material and Methods</h3><div>We prospectively enrolled 57 patients each in the full dose (FD) and low-dose (LD) protocols, respectively, to undergo abdominal CT scans using the UHR mode on a PCD-CT system (NAEOTOM Alpha), between April 2023 and September 2023. Both the FD data and LD data were then reconstructed into two series of images: (a) 0.2 mm slice thickness, reconstruction kernel Bv48, quantum iterative reconstruction (QIR) 4; (b)1 mm slice thickness, Bv40, QIR 3. The signal-to-noise ratios (SNRs) and contrast-to-noise ratios (CNRs) of seven arteries were objectively measured. The image noise, vessel sharpness, overall quality, and visibility of nine arteries were subjectively assessed by three radiologists.</div></div><div><h3>Results</h3><div>The SNRs and CNRs of 0.2 mm reconstruction set was inferior to that of 1 mm reconstruction set (p &lt; 0.001 for all the arteries and noise), however, the image quality of 0.2 mm reconstruction set was higher than that of 1 mm reconstruction set in qualitative evaluation especially for tiny arteries in Volume-rendered (VR) image (p &lt; 0.001). The SNRs and CNRs were not significantly higher for FD group than LD group on the same slice thickness except for SNRs of common hepatic artery, splenic artery and bilateral renal arteries in 0.2 mm reconstruction set. In the comparison on image quality between normal weight and overweight patients within the same reconstruction set, the results showed that low-dose scan did not significantly impact the image quality in overweight patients. The ratings of visibility of nine visceral arteries were not significantly different among FD and LD at the same thickness reconstruction set except for superior mesenteric artery (p = 0.002 and 0.007 for 0.2 mm and 1 mm reconstruction set in axial image; p = 0.002 and 0.007 for 0.2 mm and 1 mm reconstruction set in coronal image, respectively) and left gastric artery (p = 0.002 and p &lt; 0.001 for 0.2 mm and 1 mm reconstruction set in VR image, respectively).</div></div><div><h3>Conclusion</h3><div>The low-dose UHR scanning mode of PCD-CT has proven to be adequate for the clinical evaluation of visceral arteries. Utilizing a reconstruction with a slice thickness of 0.2 mm could enhance arterial depiction, particularly for small vessels.</div></div>","PeriodicalId":50928,"journal":{"name":"Academic Radiology","volume":"31 12","pages":"Pages 5087-5099"},"PeriodicalIF":3.8,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141903511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}