Advances in Anatomy Embryology and Cell Biology最新文献

4区生物学

Advances in Anatomy Embryology and Cell Biology Pub Date : 2025-01-01 DOI: 10.1007/978-3-031-70126-9_2

Albert Barth, Viv E A Perry, Lauren E Hamilton, Peter Sutovsky, Richard Oko

{"title":"Bovine Spermatogenesis.","authors":"Albert Barth, Viv E A Perry, Lauren E Hamilton, Peter Sutovsky, Richard Oko","doi":"10.1007/978-3-031-70126-9_2","DOIUrl":"https://doi.org/10.1007/978-3-031-70126-9_2","url":null,"abstract":"The intent of this chapter is to provide a morphological foundation in the normal cellular process of bovine gamete development so that abnormalities occurring are recognizable. The knowledge gained here is essential to begin to understand the significance of many of the common bull sperm abnormalities encountered in the clinics. Spermatogenesis is divided into three phases (i. e., Mitosis, Meiosis and Spermiogenesis) all happening in the seminiferous epithelium. The 'Cycle of the Bovine Seminiferous Epithelium' is explained in relation to these phases. Information is provided as to how to identify the stages of the bovine cycle and the steps of spermiogenesis at the histological and ultrastructural levels in preparation to recognize where and when in the cycle a spermatid abnormality arises. Spermiogenesis, the last phase of spermatogenesis, is the most revealing phase to recognize gamete abnormalities as this is where spermatid head and tail differentiation take place and spermatid compartments materialize. The formation of the nucleus, acrosome, manchette, perinuclear theca, axoneme, outer dense fibers, fibrous sheath, connecting piece and mitochondrial sheath occur during this phase and are evaluated. The origins and assembly of a number of essential proteins compartmentalizing the sperm head and tail as well as defects arising during spermiogenesis are reviewed.","PeriodicalId":50879,"journal":{"name":"Advances in Anatomy Embryology and Cell Biology","volume":"240 ","pages":"65-136"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144048546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Extracellular Vesicles in Implantation: Cross-Talk Between the Embryo and Endometrium. 着床中的细胞外囊泡：胚胎和子宫内膜之间的串扰。

4区生物学

Advances in Anatomy Embryology and Cell Biology Pub Date : 2025-01-01 DOI: 10.1007/102_2024_8

Muhammad Ashir Nabeel, Romana A Nowak

{"title":"Extracellular Vesicles in Implantation: Cross-Talk Between the Embryo and Endometrium.","authors":"Muhammad Ashir Nabeel, Romana A Nowak","doi":"10.1007/102_2024_8","DOIUrl":"https://doi.org/10.1007/102_2024_8","url":null,"abstract":"Extracellular vesicles (EVs), including exosomes and microvesicles, have emerged as pivotal mediators of intercellular communication. Embryo implantation is a critical process in early pregnancy and requires communication between the embryo and maternal uterus. EVs are important in coordinating the communication between the embryo and maternal uterus. This review explores EV biogenesis, molecular composition, and functional roles during implantation. It emphasizes the dynamic role of EVs in modulating the maternal-embryo dialogue, which is critical for establishing a receptive endometrium and facilitating successful implantation. EVs secreted by the embryo and endometrial cells have been shown to carry a diverse cargo of proteins, lipids, and miRNAs, which collectively influence key physiological processes, including immune tolerance, endometrial receptivity, and trophoblast invasion. EVs can be potential candidates as non-invasive biomarkers to assess the quality of embryos and uterine receptivity to enhance reproductive success. By providing a comprehensive overview of the current understanding of EVs in implantation, this chapter aims to highlight the significance of EVs in reproductive biology and their potential applications in improving fertility rates.","PeriodicalId":50879,"journal":{"name":"Advances in Anatomy Embryology and Cell Biology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142911081","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Mechanisms of Development of Sperm Defects. 精子缺陷的发育机制。

4区生物学

Advances in Anatomy Embryology and Cell Biology Pub Date : 2025-01-01 DOI: 10.1007/978-3-031-70126-9_6

Albert Barth, Viv E A Perry, Lauren E Hamilton, Peter Sutovsky, Richard Oko

{"title":"Mechanisms of Development of Sperm Defects.","authors":"Albert Barth, Viv E A Perry, Lauren E Hamilton, Peter Sutovsky, Richard Oko","doi":"10.1007/978-3-031-70126-9_6","DOIUrl":"https://doi.org/10.1007/978-3-031-70126-9_6","url":null,"abstract":"The intention of this chapter is to provide insights on the possible causes and disruptive mechanisms in play of some commonly occurring bull sperm abnormalities. Consideration is given to mutations of genes, inhibition of enzymes, deficiencies of trace elements, toxins, simulated stress, hormonal changes, hypoosmolarity and cold shock that cause similar disruptive phenotypes in development and structure seen in commonly occurring bull sperm abnormalities. The possible causes and disruptive mechanisms of the following bull sperm defects, arising from the above research, are evaluated: Tail stump, Decapitations, Dag, Dag-like, Short tail, Pseudodoplet, Segmental aplasia of the mitochondrial sheath, Coiled tails, Knobbed and Nuclear vacuolation. In addition, the idea arising from murid research, that mutations affecting sperm head shape most always affect motility, while mutations affecting sperm tail formation rarely affect sperm head shape is considered. Examples of mutations in genes or inhibition of enzymes involved with the early stages of acrosome formation are given that lead to a variety of 'globozoospermic-like' sperm head phenotypes all of which are associated with various degrees of aberrant sperm tail morphologies.","PeriodicalId":50879,"journal":{"name":"Advances in Anatomy Embryology and Cell Biology","volume":"240 ","pages":"281-296"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144037994","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Standardization of the Assessment of Bovine Spermatozoal Abnormalities, in Relation to Fertility, as Part of the Bull Breeding Soundness Examination. 与生育能力有关的牛精子异常评估标准化，作为公牛育种健全性检查的一部分。

4区生物学

Advances in Anatomy Embryology and Cell Biology Pub Date : 2025-01-01 DOI: 10.1007/978-3-031-70126-9_9

Albert Barth, Viv E A Perry, Lauren E Hamilton, Peter Sutovsky, Richard Oko

引用次数: 0

Photomicrographic Glossary of the Features of Bovine Sperm Cell Abnormalities. 牛精子细胞异常特征的显微摄影术语表。

4区生物学

Advances in Anatomy Embryology and Cell Biology Pub Date : 2025-01-01 DOI: 10.1007/978-3-031-70126-9_4

Albert Barth, Viv E A Perry, Lauren E Hamilton, Peter Sutovsky, Richard Oko

{"title":"Photomicrographic Glossary of the Features of Bovine Sperm Cell Abnormalities.","authors":"Albert Barth, Viv E A Perry, Lauren E Hamilton, Peter Sutovsky, Richard Oko","doi":"10.1007/978-3-031-70126-9_4","DOIUrl":"https://doi.org/10.1007/978-3-031-70126-9_4","url":null,"abstract":"This chapter is intended to provide an accurate visual description of normal and abnormal bovine sperm morphology as seen under the light microscope. The photographs were taken × 1000 magnification and enlarged × 1.6, unless specified otherwise, using either a) differential interference microscopy (DIC), b) phase contrast microscopy, c) eosin-nigrosin-stained sperm smears, or d) Feulgen stained smears as indicated in the legends.When viewed with a critical eye, there is an extremely wide variation in form and structure within the various categories of sperm cell abnormalities. It would be an impossible and fruitless task to attempt to show every minor variation in appearance of each type. Therefore, a series of photographs has been put together showing the main features of each type of abnormality so that any other deviation observed can easily be recognized as to the category in which it belongs.The nomenclature applied to the various abnormalities is that preferred by us, although generally accepted by other workers. Synonymous nomenclature used by other workers is included in the discussion on interpretation of sperm cell abnormalities in Chapter 5 .","PeriodicalId":50879,"journal":{"name":"Advances in Anatomy Embryology and Cell Biology","volume":"240 ","pages":"165-202"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144014461","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Ultrastructure and Composition of Bovine Spermatozoa. 牛精子的超微结构和组成。

4区生物学

Advances in Anatomy Embryology and Cell Biology Pub Date : 2025-01-01 DOI: 10.1007/978-3-031-70126-9_1

Albert Barth, Viv E A Perry, Lauren E Hamilton, Peter Sutovsky, Richard Oko

{"title":"The Ultrastructure and Composition of Bovine Spermatozoa.","authors":"Albert Barth, Viv E A Perry, Lauren E Hamilton, Peter Sutovsky, Richard Oko","doi":"10.1007/978-3-031-70126-9_1","DOIUrl":"https://doi.org/10.1007/978-3-031-70126-9_1","url":null,"abstract":"This chapter provides a cytological and compositional evaluation of the various compartments and sub-compartments making up the bull spermatozoon. The intention is to define the sperm head and tail compartments from an ultrastructural perspective and attribute to them their protein constituents gathered from both traditional and modern proteomic approaches. Common to both approaches, the compositional analysis is dependent on the fractionation and isolation of the sperm compartments combined with polyacrylamide gel electrophoresis (PAGE) and Western blotting to detect the identities of the proteins, and immunocytochemistry to confirm their residency. As will be appreciated, the identity of a particular sperm protein together with its residency provide valuable insights not only into its role, but also to the role of the specific sperm compartment it occupies, in development and/or fertilization. Attention is also given in this chapter to the consequences (on sperm structure and fertility) of inactivating genes that play key roles in sperm formation, especially if their phenotypes appear to match common bull sperm abnormalities. The keywords below cover the sperm head and tail compartments addressed in this chapter.","PeriodicalId":50879,"journal":{"name":"Advances in Anatomy Embryology and Cell Biology","volume":"240 ","pages":"1-64"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144007480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Bull Sperm Abnormalities in Practice. 公牛精子畸形的实践。

4区生物学

Advances in Anatomy Embryology and Cell Biology Pub Date : 2025-01-01 DOI: 10.1007/978-3-031-70126-9_5

Albert Barth, Viv E A Perry, Lauren E Hamilton, Peter Sutovsky, Richard Oko

引用次数: 0

Bovine Sperm Maturation. 牛精子成熟。

4区生物学

Advances in Anatomy Embryology and Cell Biology Pub Date : 2025-01-01 DOI: 10.1007/978-3-031-70126-9_3

Albert Barth, Viv E A Perry, Lauren E Hamilton, Peter Sutovsky, Richard Oko

{"title":"Bovine Sperm Maturation.","authors":"Albert Barth, Viv E A Perry, Lauren E Hamilton, Peter Sutovsky, Richard Oko","doi":"10.1007/978-3-031-70126-9_3","DOIUrl":"https://doi.org/10.1007/978-3-031-70126-9_3","url":null,"abstract":"On completion of spermatogenesis, testicular spermatozoa appear structurally mature but are infertile and must undergo a sequential maturational process in the epididymis to become motile and acquire fertilizing potential. This chapter provides a cell biological overview of the endocytic and secretory activities, along the extratesticular duct system, that provide appropriate conditions for epididymal maturation of bull spermatozoa. The compartmentalization of the bovine epididymis is illustrated and discussed in terms of epithelial cell types and merocrine and apocrine protein secretions by principal cells that influence maturation. Sequential maturational events are followed with examples, first, of testicular proteins associated with spermatozoa that are endocytosed to form a 'clean slate' and then, of epididymal secretory proteins that recondition the sperm milieu and bind to spermatozoa in order to attain its full fertilization potential. Finally, an assessment is made of the potential contributions to epididymal maturation of some well-characterized and identified secretory proteins that interact with the cytoplasmic membrane of spermatozoa.","PeriodicalId":50879,"journal":{"name":"Advances in Anatomy Embryology and Cell Biology","volume":"240 ","pages":"137-164"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144031289","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Assessing Bovine Male Fertility in a Technological Age. 评估技术时代的牛雄性生育能力。

4区生物学

Advances in Anatomy Embryology and Cell Biology Pub Date : 2025-01-01 DOI: 10.1007/978-3-031-70126-9_7

Albert Barth, Viv E A Perry, Lauren E Hamilton, Peter Sutovsky, Richard Oko

引用次数: 0

Prenatal and Preweaning Environmental Effects upon Pubertal Development and Sperm Production. 产前和断奶前环境对青春期发育和精子产生的影响。

4区生物学

Advances in Anatomy Embryology and Cell Biology Pub Date : 2025-01-01 DOI: 10.1007/978-3-031-70126-9_8

Albert Barth, Viv E A Perry, Lauren E Hamilton, Peter Sutovsky, Richard Oko

引用次数: 0