Advances in Anatomy Embryology and Cell Biology最新文献_第10页

The Pulmonary Vascular Barrier: Insights into Structure, Function, and Regulatory Mechanisms. 肺血管屏障:结构、功能和调节机制。

4区生物学

Advances in Anatomy Embryology and Cell Biology Pub Date : 2018-01-01 DOI: 10.1007/978-3-319-68483-3_3

Kaushik Parthasarathi

引用次数: 8

Chemoarchitecture of the Pulvinar. Pulvinar的化学结构。

4区生物学

Advances in Anatomy Embryology and Cell Biology Pub Date : 2018-01-01 DOI: 10.1007/978-3-319-70046-5_3

Ricardo Gattass, Juliana G M Soares, Bruss Lima

引用次数: 0

Visual Map Representations in the Primate Pulvinar. 灵长类动物的视觉地图表征。

4区生物学

Advances in Anatomy Embryology and Cell Biology Pub Date : 2018-01-01 DOI: 10.1007/978-3-319-70046-5_4

Ricardo Gattass, Juliana G M Soares, Bruss Lima

引用次数: 1

Comparative View of Lung Vascular Endothelium of Cattle, Horses, and Water Buffalo. 牛、马和水牛肺血管内皮的比较研究。

4区生物学

Advances in Anatomy Embryology and Cell Biology Pub Date : 2018-01-01 DOI: 10.1007/978-3-319-68483-3_2

David Schneberger, Ram S Sethi, Baljit Singh

引用次数: 2

Pulmonary Endothelial Cell Apoptosis in Emphysema and Acute Lung Injury. 肺气肿和急性肺损伤中的肺内皮细胞凋亡。

4区生物学

Advances in Anatomy Embryology and Cell Biology Pub Date : 2018-01-01 DOI: 10.1007/978-3-319-68483-3_4

Eboni Chambers, Sharon Rounds, Qing Lu

引用次数: 52

Introduction. 介绍。

4区生物学

Advances in Anatomy Embryology and Cell Biology Pub Date : 2018-01-01 DOI: 10.1007/978-3-319-63187-5_1

Jason G Knott, Keith E Latham

引用次数: 0

CHD1 Controls Cell Lineage Specification Through Zygotic Genome Activation. CHD1通过合子基因组激活控制细胞谱系规范。

4区生物学

Advances in Anatomy Embryology and Cell Biology Pub Date : 2018-01-01 DOI: 10.1007/978-3-319-63187-5_3

Shinnosuke Suzuki, Naojiro Minami

{"title":"CHD1 Controls Cell Lineage Specification Through Zygotic Genome Activation.","authors":"Shinnosuke Suzuki, Naojiro Minami","doi":"10.1007/978-3-319-63187-5_3","DOIUrl":"https://doi.org/10.1007/978-3-319-63187-5_3","url":null,"abstract":"In mammals, the processes spanning from fertilization to the generation of a new organism are very complex and are controlled by multiple genes. Life begins with the encounter of eggs and spermatozoa, in which gene expression is inactive prior to fertilization. After several cell divisions, cells arise that are specialized in implantation, a developmental process unique to mammals. Cells involved in the establishment and maintenance of implantation differentiate from totipotent embryos, and the remaining cells generate the embryo proper. Although this process of differentiation, termed cell lineage specification, is supported by various gene expression networks, many components have yet to be identified. Moreover, despite extensive research it remains unclear which genes are controlled by each of the factors involved. Although it has become clear that epigenetic factors regulate gene expression, elucidation of the underlying mechanisms remains challenging. In this chapter, we propose that the chromatin remodeling factor CHD1, together with epigenetic factors, is involved in a subset of gene expression networks involved in processes spanning from zygotic genome activation to cell lineage specification.","PeriodicalId":50879,"journal":{"name":"Advances in Anatomy Embryology and Cell Biology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/978-3-319-63187-5_3","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35286336","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

ROCK and RHO Playlist for Preimplantation Development: Streaming to HIPPO Pathway and Apicobasal Polarity in the First Cell Differentiation. 植入前发育的ROCK和RHO播放列表:第一细胞分化中流向HIPPO通路和顶基极性。

4区生物学

Advances in Anatomy Embryology and Cell Biology Pub Date : 2018-01-01 DOI: 10.1007/978-3-319-63187-5_5

Vernadeth B Alarcon, Yusuke Marikawa

{"title":"ROCK and RHO Playlist for Preimplantation Development: Streaming to HIPPO Pathway and Apicobasal Polarity in the First Cell Differentiation.","authors":"Vernadeth B Alarcon, Yusuke Marikawa","doi":"10.1007/978-3-319-63187-5_5","DOIUrl":"https://doi.org/10.1007/978-3-319-63187-5_5","url":null,"abstract":"In placental mammalian development, the first cell differentiation produces two distinct lineages that emerge according to their position within the embryo: the trophectoderm (TE, placenta precursor) differentiates in the surface, while the inner cell mass (ICM, fetal body precursor) forms inside. Here, we discuss how such position-dependent lineage specifications are regulated by the RHOA subfamily of small GTPases and RHO-associated coiled-coil kinases (ROCK). Recent studies in mouse show that activities of RHO/ROCK are required to promote TE differentiation and to concomitantly suppress ICM formation. RHO/ROCK operate through the HIPPO signaling pathway, whose cell position-specific modulation is central to establishing unique gene expression profiles that confer cell fate. In particular, activities of RHO/ROCK are essential in outside cells to promote nuclear localization of transcriptional co-activators YAP/TAZ, the downstream effectors of HIPPO signaling. Nuclear localization of YAP/TAZ depends on the formation of apicobasal polarity in outside cells, which requires activities of RHO/ROCK. We propose models of how RHO/ROCK regulate lineage specification and lay out challenges for future investigations to deepen our understanding of the roles of RHO/ROCK in preimplantation development. Finally, as RHO/ROCK may be inhibited by certain pharmacological agents, we discuss their potential impact on human preimplantation development in relation to fertility preservation in women.","PeriodicalId":50879,"journal":{"name":"Advances in Anatomy Embryology and Cell Biology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/978-3-319-63187-5_5","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35286338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 9

Connectivity of the Pulvinar. Pulvinar的连通性。

4区生物学

Advances in Anatomy Embryology and Cell Biology Pub Date : 2018-01-01 DOI: 10.1007/978-3-319-70046-5_5

Ricardo Gattass, Juliana G M Soares, Bruss Lima

引用次数: 2

Atomistic Simulations of Electroporation of Model Cell Membranes. 模型细胞膜电穿孔的原子模拟。

4区生物学

Advances in Anatomy Embryology and Cell Biology Pub Date : 2017-01-01 DOI: 10.1007/978-3-319-56895-9_1

Mounir Tarek

引用次数: 5