Aktuelle Rheumatologie最新文献

{"title":"Bariatrische Operation führt nicht zu niedrigem Knie- und Hüftarthrose-Risiko","authors":"","doi":"10.1055/a-2117-6602","DOIUrl":"https://doi.org/10.1055/a-2117-6602","url":null,"abstract":"Die bariatrische Chirurgie ist eine wirksame Adipositastherapie, die zu einer langfristigen Gewichtsreduzierung führt. Bisher wurde nicht gezeigt, ob die bariatrische Chirurgie mit einem geringeren Risiko für Hüft- und Kniearthrose und einer Verringerung des Bedarfs an Arthroplastik einhergeht. Lohmander et al. untersuchten das langfristige Arthroserisiko und die Notwendigkeit von Hüft- und Knieendoprothesen nach bariatrischen Operationen.","PeriodicalId":50831,"journal":{"name":"Aktuelle Rheumatologie","volume":"252 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139221786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Kniearthrose: GLAD-Programm wirkt nicht besser als Placebo","authors":"","doi":"10.1055/a-2117-6664","DOIUrl":"https://doi.org/10.1055/a-2117-6664","url":null,"abstract":"Zur Behandlung einer Arthrose wird eine Bewegungstherapie in Kombination mit einer Patientenaufklärung empfohlen. Auf der Grundlage dieser Empfehlungen wurde das Programm Good Life with Osteoarthritis in Denmark (GLAD) entwickelt und in mehreren Ländern weltweit eingeführt. Henriksen et al. bewerteten GLAD im Vergleich zu einem Placebo auf die Behandlungsresultate.","PeriodicalId":50831,"journal":{"name":"Aktuelle Rheumatologie","volume":"26 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139224664","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"axSpA-Patienten haben häufig arbeitsbezogene Probleme","authors":"","doi":"10.1055/a-2117-6716","DOIUrl":"https://doi.org/10.1055/a-2117-6716","url":null,"abstract":"Eine Zunahme der Krankheitsaktivität der axialen Spondyloarthritis (axSpA) ist mit einem Verlust an Arbeitsproduktivität verbunden, was eine größere Krankheitslast und höhere Kosten für die Gesellschaft bedeutet. Zudem haben axSpA-Patienten oftmals Schwierigkeiten, in ihrem Beruf voranzukommen. Inman et al. untersuchten Faktoren, die mit arbeitsbezogenen Problemen bei kanadischen axSpA-Patienten in Verbindung stehen.","PeriodicalId":50831,"journal":{"name":"Aktuelle Rheumatologie","volume":"59 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139226944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Anti-C5aR-Antikörper geben Aufschluss zu AAV-Krankheitsaktivität","authors":"","doi":"10.1055/a-2117-6752","DOIUrl":"https://doi.org/10.1055/a-2117-6752","url":null,"abstract":"Die durch den G-Protein-gekoppelten Rezeptor C5aR gesteuerte Rekrutierung von Neutrophilen, Aktivierung und Entzündung spielt eine wichtige Rolle in der Pathogenese der antineutrophilen zytoplasmatischen Autoantikörper (ANCA)- assoziierten Vaskulitis (AAV). Interessanterweise werden Antikörper, die u. a. auf C5aR abzielen, in niedrigen Konzentrationen auch bei gesunden Menschen nachgewiesen. Klapa et al. untersuchten die Zusammenhänge.","PeriodicalId":50831,"journal":{"name":"Aktuelle Rheumatologie","volume":"52 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139225673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rheumatoide Arthritis: Sozioökonomische Instabilität begünstigt Behinderungen","authors":"","doi":"10.1055/a-2117-6690","DOIUrl":"https://doi.org/10.1055/a-2117-6690","url":null,"abstract":"Dank der modernen Therapien gelingt es bei der Mehrzahl der Menschen mit einer rheumatoiden Arthritis (RA), die Inflammation langfristig gut unter Kontrolle zu halten. Bei vielen Betroffenen spiegelt sich dieser Behandlungserfolg allerdings nicht in einer Reduktion von Behinderungen wider. Liegt das möglicherweise an sozialen, ökonomischen oder Lebensstilfaktoren? Und welche Rolle spielen diesbezüglich Schmerzen, Angst, Fatigue und Depressionen?","PeriodicalId":50831,"journal":{"name":"Aktuelle Rheumatologie","volume":"51 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139221480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Handchirurgie bei entzündlich rheumatischen Erkrankungen – ein Update","authors":"R. Gaulke","doi":"10.1055/a-2189-0527","DOIUrl":"https://doi.org/10.1055/a-2189-0527","url":null,"abstract":"Zusammenfassung Die peripheren Gelenke an Händen und Füßen sind bei entzündlich-rheumatischen Erkrankungen und hier insbesondere bei der rheumatoiden Arthritis und bei Arthritis psoriatica sehr häufig von der Entzündung betroffen. Neben den Gelenken sind besonders die Entzündungen der Sehnenscheiden zu beachten, da diese unbehandelt zu einer Durchwanderung der Sehne führen können welche dann Defektrupturen bedingen. Die Rekonstruktion dieser langstreckig geschädigten Sehnen ist aufwendig und die Ergebnisse sind schlechter als die der Tenosynovialektomie. Sollte eine ansonsten wirksamer Basistherapie an einzelnen Gelenken der Hand nicht zu einer Beruhigung der Entzündung führen, so ist die operative Synovialektomie zum Gelenkserhalt indiziert. Da neben den Gelenken der Hand auch häufig Destruktionen mit Bewegungseinschränkungen am Schulter- und Ellenbogengelenk auftreten, sollte bei Destruktionen im Handgelenk nicht generell eine komplette Arthrodese durchgeführt werden, so lange noch Gelenkkompartimente erhalten sind. Es bestehen zahlreiche Möglichkeiten durch karpale Teilarthrodesen die Schmerzen zu nehmen, das Handgelenk zu stabilisieren und eine Restbeweglichkeit zu erhalten. Für instabile und destruierte Fingergrundgelenke ist der Swanson-Spacer weiterhin der Goldstandard. Für die Fingermittelgelenke steht mittlerweile seit mehreren Jahren ein Oberflächenersatz zur Verfügung, welcher eine gute Osteointegration zeigt und damit die stielgeführten Prothesen, die in der Regel nicht einheilen oder gehäuft zu periprothetischen Frakturen führen, abgelöst hat. Die Operation sollte an der entzündlich-rheumatisch veränderten Hand streng aber dennoch konsequent und ohne zeitliche Verzögerung gestellt werden, um so viele Gelenke wie möglich zu erhalten. Da viele Destruktionen und Fehlstellungen entzündlich-rheumatischer Genese radiologisch posttraumatischen und degenerativen Veränderungen ähneln, aber dennoch unterschiedlicher chirurgischer Therapie bedürfen, sollten diese dem orthopädischen Rheumatologen zugeführt werden, um das bestmögliche Ergebnis zu erzielen und Folgeoperation möglichst zu vermeiden.","PeriodicalId":50831,"journal":{"name":"Aktuelle Rheumatologie","volume":"160 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139248636","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Erratum: Adherence to Colchicine During Pregnancy in Familial Mediterranean Fever Patients: Reasons for Cessation and Outcomes from a Single-Centre Experience","authors":"İsmail Dogan, S. Güven, Ö. Karakaş, Esra Kayacan Erdoğan, Ş. Erten","doi":"10.1055/a-2189-8554","DOIUrl":"https://doi.org/10.1055/a-2189-8554","url":null,"abstract":"","PeriodicalId":50831,"journal":{"name":"Aktuelle Rheumatologie","volume":"9 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139290371","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Classification Criteria For Early Knee Osteoarthritis: A Review Article","authors":"Luz Herrero-Manley, Ana Alabajos-Cea, Luis Suso-Martí, Enrique Viosca-Herrero","doi":"10.1055/a-2173-1607","DOIUrl":"https://doi.org/10.1055/a-2173-1607","url":null,"abstract":"Abstract Objective The aim of this systematic review (SR) was to define the “state of the art” on classification criteria for early knee osteoarthritis (EKOA). Methods A systematic review was performed using MEDLINE (Pubmed), Web of Science, Scopus, EMBASE, PEDro, CINAHL and Google scholar databases. Two independent reviewers conducted the eligibility review. Any type of study that proposed diagnostic criteria of EKOA was included. Results Seven articles were included according to the inclusion criteria. The evidence presented in this SR shows that there is still no consensus regarding definition and classification of EKOA. At present, there are seven different proposals in the scientific literature, and they only agree on including knee pain and radiographic evaluation in their criteria, but they do not even consider the same situations for including these two factors. Conclusion There is still no consensus regarding definition and classification of EKOA. Knee pain and radiological assessment seem to be the most commonly used criteria, but due to the variability encountered, it is not possible to reach a consensus on a clear definition and diagnosis of EOKA.","PeriodicalId":50831,"journal":{"name":"Aktuelle Rheumatologie","volume":"53 4","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135266384","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Portuguese state of the art on osteoporosis and fracture risk: an update on the treatment options","authors":"Diogo Ramalho, Gustavo Melo Rocha, Maria João Oliveira","doi":"10.1055/a-2158-0872","DOIUrl":"https://doi.org/10.1055/a-2158-0872","url":null,"abstract":"Abstract Osteoporosis and fragility fractures are serious public health problems, which greatly impact individual health and the economy of other health services. Pharmacological treatment is still one of the main elements of clinical intervention, combined with non-pharmacological measures, in preventing the occurrence of fragility fractures. The emergence of promising new pharmacological options in the treatment of osteoporosis seems to renew expectations in the prevention of complications and a subsequent reduction in morbidity and mortality, including symptomatic treatment, improved physical function and a better quality of life. This review aims to provide updated information on the pharmacological treatment of osteoporosis in the adult population. A comprehensive PubMed search was performed to review the current evidence on osteoporosis treatment. Of the 378 articles identified from the initial queries, the final review included 80 articles. Currently, the following pharmacological options are available: antiresorptive (bisphosphonates, denosumab, postmenopausal hormone replacement therapy and selective oestrogen receptor modulators), bone-forming agents (essentially, teriparatide and abaloparatide) and the new dual-action therapy (romosozumab), recently approved by the US Food and Drug Administration and the European Medicines Agency, but which is not yet an option in Portugal. Therapeutic selection is essentially based on assessment of cost-effectiveness, since current evidence does not suggest any differences between the distinctive classes in reducing the risk of fractures, but this analysis is limited by the scarcity of comparative intraclass studies. Notwithstanding, romosozumab, as a dual effect therapy, is promising in resolving the physiological limitations resulting from the merely unilateral action of antiresorptive agents and bone-forming agents in the inseparable relationship between bone formation and resorption. However, its cardiovascular safety raises some concerns, and this topic is still being debated. The underdiagnosis and the undertreatment of osteoporosis remain one of the greatest challenges of the 21st century. Over the years, new drugs have appeared that have tried to address these problems with a direct impact on the health of populations, but a long way remains to be come in optimising their effectiveness, safety and tolerability.","PeriodicalId":50831,"journal":{"name":"Aktuelle Rheumatologie","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135266391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation Of The Relationship Of Kinesiophobia With Anxiety, Upper Extremity Disability And Quality Of Life In Patients With Frozen Shoulders","authors":"öznur Uysal Batmaz, Burkay Yakar, Tacettin Mirzaoğlu, Ahmet Yılmaz, Serda Em, Ibrahim Batmaz","doi":"10.1055/a-2154-8295","DOIUrl":"https://doi.org/10.1055/a-2154-8295","url":null,"abstract":"Abstract Introduction Frozen shoulder is a painful shoulder disease in which glenohumeral joint movements are actively and passively restricted in all directions. If not treated, it can cause various psychological diseases and muscle and joint diseases. Kinesiophobia; this is defined as a fear of physical activity resulting from excessive sensitivity and an uncomfortable feeling due to painful or repeated injury. In this study, it was aimed to evaluate the relationship of kinesiophobia to upper extremity disability, anxiety and quality of life in patients with frozen shoulder. Materials and methods Fırat University Faculty of Medicine, Department of Physical Medicine and Rehabilitation, between September 2020 and March 2021; As a result of clinical evaluation and radiological examinations, patients were enrolled between the ages of 18–75 and who agreed to participate in the study; 48 patients were diagnosed with frozen shoulder and met the inclusion and exclusion criteria of the study and were included in the patient group; Fourty healthy subjects aged between 18–75 years, who did not have shoulder disease and who met the inclusion and exclusion criteria of the study, were included in the control group. A total of 88 cases were included in the study. The following scales were used. TAMPA kinesiophobia scale to assess kinesiophobia in patients and control group, Beck Anxiety scale to assess anxiety in patient group; The Disabilities of The Arm, Shoulder and Hand (DASH) scale to assess upper extremity disability; Short Form (SF)-36 was used to assess quality of life. Results TAMPA kinesiophobia scale was found to be significantly different in the patient group when the patient group and control group were compared. According to the correlation analysis, the TAMPA kinesiophobia scale showed a positive correlation with the Beck-Anxiety and DASH scales in the patient group, while a negative correlation was found with the SF36-Physical function, emotional role difficulty and social functionality. Conclusion In patients with frozen shoulder, kinesiophobia seems to be associated with increased anxiety and upper extremity disability, as well as low quality of life. Structural disorders as well as psychological factors should be taken into account among the reasons for the prolonged limitation of movement and delayed recovery. When the physicians serving in the primary care are experienced with patient management with frozen shoulder, as evaluated for therapeutic purposes, planning psychological support treatments in addition to medical and physical therapy will increase the quality of health care provided to patients.","PeriodicalId":50831,"journal":{"name":"Aktuelle Rheumatologie","volume":"28 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136142325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}