American Journal of Alzheimers Disease and Other Dementias最新文献_第7页

Cerebrovascular Disease Is a Risk for Getting Lost Behavior in Prodromal Dementia. 脑血管疾病是前驱痴呆症患者迷路行为的风险因素之一

IF 3.4 4区医学

American Journal of Alzheimers Disease and Other Dementias Pub Date : 2019-08-01 Epub Date: 2019-05-29 DOI: 10.1177/1533317519852864

Chathuri Yatawara, Kok Pin Ng, Levinia Lim, Russell Chander, Juan Zhou, Nagaendran Kandiah

{"title":"Cerebrovascular Disease Is a Risk for Getting Lost Behavior in Prodromal Dementia.","authors":"Chathuri Yatawara, Kok Pin Ng, Levinia Lim, Russell Chander, Juan Zhou, Nagaendran Kandiah","doi":"10.1177/1533317519852864","DOIUrl":"10.1177/1533317519852864","url":null,"abstract":"Cerebrovascular disease (CVD) contributes to spatial navigation deficits; however, the everyday outcomes of this association remain unexplored. We investigated whether CVD was a risk for getting lost behavior (GLB) in elderly with mild cognitive impairment (MCI) and mild Alzheimer disease (AD). Getting lost behavior was assessed using a semistructured clinical interview and was associated with white matter lesions (WMLs) in patients with MCI. Specifically, right occipital WMLs increased the odds of GLB by 12 times (P = .03) and right temporal WMLs increased the odds of GLB by 4 times (P = .01), regardless of age, gender, global cognitive impairment, and occipital or medial temporal gray matter atrophy. Hypertension increased the risk of GLB in MCI by contributing to the burden of WMLs. White matter lesions were not associated with GLB in mild AD. Our findings suggest that interventions aimed at reducing GLB in prodromal dementia may involve preventing WMLs by optimizing hypertension control.","PeriodicalId":50816,"journal":{"name":"American Journal of Alzheimers Disease and Other Dementias","volume":"34 5","pages":"344-352"},"PeriodicalIF":3.4,"publicationDate":"2019-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10852500/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37023122","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of CYP2D6 and CYP3A4 Genotypes on the Efficacy of Cholinesterase Inhibitors in Southern Chinese Patients With Alzheimer's Disease. 中国南方阿尔茨海默病患者的 CYP2D6 和 CYP3A4 基因型对胆碱酯酶抑制剂疗效的影响

IF 3.4 4区医学

American Journal of Alzheimers Disease and Other Dementias Pub Date : 2019-08-01 Epub Date: 2019-05-07 DOI: 10.1177/1533317519848237

Suk Ling Ma, Nelson Leung Sang Tang, Karen Hong Yun Wat, Jenny Hoi Yin Tang, Ka Hin Lau, Chun Bon Law, John Chiu, Cindy Chi Woon Tam, Tin Keung Poon, Ka Leung Lin, Carolyn Poey Lyn Kng, Hing Leung Kong, Tak Yeung Chan, Wai Chi Chan, Linda Chiu Wa Lam

{"title":"Effect of CYP2D6 and CYP3A4 Genotypes on the Efficacy of Cholinesterase Inhibitors in Southern Chinese Patients With Alzheimer's Disease.","authors":"Suk Ling Ma, Nelson Leung Sang Tang, Karen Hong Yun Wat, Jenny Hoi Yin Tang, Ka Hin Lau, Chun Bon Law, John Chiu, Cindy Chi Woon Tam, Tin Keung Poon, Ka Leung Lin, Carolyn Poey Lyn Kng, Hing Leung Kong, Tak Yeung Chan, Wai Chi Chan, Linda Chiu Wa Lam","doi":"10.1177/1533317519848237","DOIUrl":"10.1177/1533317519848237","url":null,"abstract":"Alzheimer's disease (AD) is the most prevalent form of dementia, and age is strongly associated with the incidence of AD. This study aimed to investigate the association between the genotypes of CYP2D6, CYP3A4, and CYP2C9 genes to the clinical efficacy and tolerability of cholinesterase inhibitors (ChEIs) in Chinese patients with AD. One hundred seventy-nine patients with AD with newly prescribed with ChEIs were recruited. The clinical response and tolerability were evaluated at baseline, 3rd-, 6th-, and 12th-month follow-ups and were compared according to their genotypes of CYP2D6, CYP3A4, and CYP2C9. Among patients prescribed with donepezil/galantamine, CYP2D6*10 carriers showed significantly less side effects (P = .009). CYP2D6*10 carriers responded better to ChEIs and resulted in better improvement in Alzheimer's Disease Assessment Scale-Cognitive subscale (P = .027) and Mini-Mental State Examination (P = .012). Further study is required to replicate the finding, and it might be useful for clinicians to decide the medication based on the patients' CYP genotypes.","PeriodicalId":50816,"journal":{"name":"American Journal of Alzheimers Disease and Other Dementias","volume":"34 5","pages":"302-307"},"PeriodicalIF":3.4,"publicationDate":"2019-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10852420/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37217953","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Musical Features and Affective Responses to Personalized Playlists in People With Probable Dementia. 疑似痴呆症患者对个性化播放列表的音乐特征和情感反应

IF 3.4 4区医学

American Journal of Alzheimers Disease and Other Dementias Pub Date : 2019-06-01 Epub Date: 2018-10-21 DOI: 10.1177/1533317518808011

Sandra Garrido, Catherine J Stevens, Esther Chang, Laura Dunne, Janette Perz

{"title":"Musical Features and Affective Responses to Personalized Playlists in People With Probable Dementia.","authors":"Sandra Garrido, Catherine J Stevens, Esther Chang, Laura Dunne, Janette Perz","doi":"10.1177/1533317518808011","DOIUrl":"10.1177/1533317518808011","url":null,"abstract":"Objectives: Personalized music playlists are increasingly being utilized in aged care settings. This study aims to investigate how musical features influence the affective response to music of people with probable dementia.Methods: A factorial experiment (2 × 2 × 3) was conducted to investigate the influence of tempo (fast, slow), mode (major, minor), and lyrics (none, negative, positive). Ninety-nine people with probable dementia were randomly assigned to 3 conditions, listening to 3 personalized playlists. Galvanic skin response and activation of facial action units were measured.Results: Music with fast tempos increased arousal and reduced enjoyment. Music in minor keys increased activation of the depressor anguli oris, suggesting increased sadness. Lyrics had no significant effect on response.Discussion: The findings demonstrate that both tempo and mode influenced the response of the listener. As well as accounting for personal preferences, music for people with dementia should be carefully targeted toward the affective outcome desired.","PeriodicalId":50816,"journal":{"name":"American Journal of Alzheimers Disease and Other Dementias","volume":"34 4","pages":"247-253"},"PeriodicalIF":3.4,"publicationDate":"2019-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10852458/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36646135","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Role of Gender in Shame, Hostility, and Aggression Experienced by Caregivers for Patients With Dementia. 性别在痴呆症患者护理者所经历的羞耻感、敌意和攻击中的作用。

IF 3.4 4区医学

American Journal of Alzheimers Disease and Other Dementias Pub Date : 2019-06-01 Epub Date: 2018-10-07 DOI: 10.1177/1533317518802458

Konstantina Avdikou, Charalampos Stefanatos, Marianna Tsatali, Mairy Gouva, Magda Tsolaki

{"title":"The Role of Gender in Shame, Hostility, and Aggression Experienced by Caregivers for Patients With Dementia.","authors":"Konstantina Avdikou, Charalampos Stefanatos, Marianna Tsatali, Mairy Gouva, Magda Tsolaki","doi":"10.1177/1533317518802458","DOIUrl":"10.1177/1533317518802458","url":null,"abstract":"The aim of this study was to investigate the differences between male and female caregivers for patients with dementia in the way they experience various psychosocial parameters such as shame, hostility, and aggression. The sample included 55 caregivers of patients with moderate and severe dementia, whereas the average age was 51 years. Female caregivers were found to experience significantly higher levels of external shame, measured by Other As Shamer scale, than male caregivers, t (53) = 2.54, P < .01. A significant difference was also found between the female and male caregivers regarding their recorded levels of internal shame, measured by Experience of Shame Scale, with female caregivers experiencing more internal shame than their male counterparts, t (53) = 2.11, P < .01. However, no significant differences were found in hostility and aggression between males and females. These results demonstrate the existence of gender differences in the levels of shame experienced by care providers for patients with dementia.","PeriodicalId":50816,"journal":{"name":"American Journal of Alzheimers Disease and Other Dementias","volume":"34 4","pages":"231-235"},"PeriodicalIF":3.4,"publicationDate":"2019-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10852499/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36553735","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Excessive Daytime Sleepiness in Major Dementia Syndromes. 主要痴呆综合征的日间过度嗜睡。

IF 3.4 4区医学

American Journal of Alzheimers Disease and Other Dementias Pub Date : 2019-06-01 Epub Date: 2019-02-10 DOI: 10.1177/1533317519828046

Angelica Boeve, Tanis J Ferman, Jeremiah Aakre, Erik St Louis, Michael Silber, Mary Machulda, Julie Fields, Neill Graff-Radford, Michelle Mielke, Yonas Geda, David Jones, Jonathon Graff-Radford, David Knopman, Ronald Petersen, Brad Boeve

{"title":"Excessive Daytime Sleepiness in Major Dementia Syndromes.","authors":"Angelica Boeve, Tanis J Ferman, Jeremiah Aakre, Erik St Louis, Michael Silber, Mary Machulda, Julie Fields, Neill Graff-Radford, Michelle Mielke, Yonas Geda, David Jones, Jonathon Graff-Radford, David Knopman, Ronald Petersen, Brad Boeve","doi":"10.1177/1533317519828046","DOIUrl":"https://doi.org/10.1177/1533317519828046","url":null,"abstract":"There has been no comparison of excessive daytime sleepiness (EDS) in patients with Alzheimer's disease dementia (AD), dementia with Lewy bodies (DLB), and behavioral variant frontotemporal dementia (bvFTD). We identified patients with mild dementia who met criteria for these disorders who also had the Epworth Sleepiness Scale (ESS) completed. The sample included 17 bvFTD, 111 AD, and 31 DLB. An ESS score ≥10 was considered abnormal and consistent with EDS. Analyses with age and sex as covariates revealed higher mean ESS scores for DLB compared to the other groups (DLB 13.9 [5], bvFTD 9.6 [8], AD 8.8 [5], P < .05). An ESS score ≥10 was significantly more likely to occur in DLB compared to bvFTD or AD (DLB 81% vs bvFTD 47% vs AD 45%, P < .01). In patients with mild dementia, EDS is greatest in DLB and comparably lower in bvFTD and AD.","PeriodicalId":50816,"journal":{"name":"American Journal of Alzheimers Disease and Other Dementias","volume":"34 4","pages":"261-264"},"PeriodicalIF":3.4,"publicationDate":"2019-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/1533317519828046","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36545005","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 11

High Risk of Suicide in Behavioral Variant Frontotemporal Dementia. 行为变异型额颞叶痴呆症患者自杀风险高。

IF 3.4 4区医学

American Journal of Alzheimers Disease and Other Dementias Pub Date : 2019-06-01 Epub Date: 2018-12-17 DOI: 10.1177/1533317518817609

Milena Zucca, Elisa Rubino, Alessandro Vacca, Flora Govone, Annalisa Gai, Paola De Martino, Silvia Boschi, Salvatore Gentile, Maria Teresa Giordana, Innocenzo Rainero

{"title":"High Risk of Suicide in Behavioral Variant Frontotemporal Dementia.","authors":"Milena Zucca, Elisa Rubino, Alessandro Vacca, Flora Govone, Annalisa Gai, Paola De Martino, Silvia Boschi, Salvatore Gentile, Maria Teresa Giordana, Innocenzo Rainero","doi":"10.1177/1533317518817609","DOIUrl":"10.1177/1533317518817609","url":null,"abstract":"Aim: The purpose of the study was to determine the prevalence of suicidal ideation and attempts in patients with behavioral variant frontotemporal dementia (bvFTD), evaluating possible risk factors for suicidality.Methods: Risk of suicide was assessed using the Scale for Suicide Ideation (SSI) in 35 patients with bvFTD and 25 controls.Results: According to SSI, 40% of patients with bvFTD had suicidal ideation in comparison to 8% of controls ( P = .009). Four patients with bvFTD have attempted suicide versus none control ( P = .006). Patients with bvFTD with suicide risk showed higher levels of anxiety, depression, stress, and hopelessness than patients without suicide risk ( P < .001). Patients who attempted suicide were younger and had a longer disease duration than those with only suicide ideation. Intriguingly, 40% of patients with parkinsonism presented high level of suicide ideation.Conclusions: Our findings show that patients with bvFTD have a high risk of suicide. Additional studies in larger populations are needed to confirm our results.","PeriodicalId":50816,"journal":{"name":"American Journal of Alzheimers Disease and Other Dementias","volume":"34 4","pages":"265-271"},"PeriodicalIF":3.4,"publicationDate":"2019-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10852495/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36789879","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Constant Observation Practices for Hospitalized Persons With Dementia: A Survey Study. 痴呆症住院患者的持续观察实践：调查研究。

IF 3.4 4区医学

American Journal of Alzheimers Disease and Other Dementias Pub Date : 2019-06-01 Epub Date: 2019-01-31 DOI: 10.1177/1533317519826272

Liron Sinvani, Andrew Strunk, Vidhi Patel, Shalin Shah, Colm Mulvany, Andrzej Kozikowski, Marie Boltz, Renee Pekmezaris, Gisele Wolf-Klein

{"title":"Constant Observation Practices for Hospitalized Persons With Dementia: A Survey Study.","authors":"Liron Sinvani, Andrew Strunk, Vidhi Patel, Shalin Shah, Colm Mulvany, Andrzej Kozikowski, Marie Boltz, Renee Pekmezaris, Gisele Wolf-Klein","doi":"10.1177/1533317519826272","DOIUrl":"10.1177/1533317519826272","url":null,"abstract":"Despite substantial staffing and cost implications, the use of constant observation (CO) has been poorly described in the acute care setting. The purpose of this cross-sectional, multicenter, survey study was to assess hospital provider practices regarding the use of CO. Of the 543 surveys distributed, 231 were completed across 5 sites. Most respondents worked on medical units (67.5%), as nurses (49.1%); 44.8% were white; and 75.6% were female. The majority (84.2%) reported at least 1 patient/wk requiring CO. Most frequent indication for CO was dementia with agitation (60.7%), in patients older than 70 (62.3%) and predominantly by nurse assistants (93.9%). Almost half (47.3%) stated they felt pressured to discontinue CO, despite a strong perceived benefit (76%). Enhanced observation (92.6%) was most frequently used to decrease CO. Finally, 77.9% perceived that those performing CO lacked training. Our study highlights the widespread use of CO for hospitalized older adults with dementia.","PeriodicalId":50816,"journal":{"name":"American Journal of Alzheimers Disease and Other Dementias","volume":"34 4","pages":"223-230"},"PeriodicalIF":3.4,"publicationDate":"2019-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10852488/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36964010","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Telephone-Based Cognitive Behavioral Intervention Improves Dementia Caregivers' Quality of Life. 基于电话的认知行为干预改善了痴呆症照护者的生活质量。

IF 3.4 4区医学

American Journal of Alzheimers Disease and Other Dementias Pub Date : 2019-06-01 Epub Date: 2019-01-13 DOI: 10.1177/1533317518822100

Franziska Meichsner, Nils F Töpfer, Maren Reder, Renate Soellner, Gabriele Wilz

{"title":"Telephone-Based Cognitive Behavioral Intervention Improves Dementia Caregivers' Quality of Life.","authors":"Franziska Meichsner, Nils F Töpfer, Maren Reder, Renate Soellner, Gabriele Wilz","doi":"10.1177/1533317518822100","DOIUrl":"10.1177/1533317518822100","url":null,"abstract":"The present study examined the effects of a telephone-based cognitive behavioral intervention on dementia caregivers' quality of life (QoL). A total of 273 caregivers were randomly assigned to an intervention or control group. The intervention comprised 12 telephone sessions of individual cognitive behavioral therapy (CBT) over 6 months. At baseline, postintervention, and 6-month follow-up, QoL was assessed with the World Health Organization QoL-BREF, which measures perceived QoL for the domains physical health, psychological health, social relationships, and environment as well as overall QoL and satisfaction with general health. Intention-to-treat analyses using latent change models were performed. At postintervention, intervention group participants reported better overall QoL and satisfaction with general health as well as better physical and psychological health compared to control group participants. Together with existing evidence, the results suggest that the telephone CBT intervention does not only reduce impairments but also fosters improvements in health-related QoL.","PeriodicalId":50816,"journal":{"name":"American Journal of Alzheimers Disease and Other Dementias","volume":"34 4","pages":"236-246"},"PeriodicalIF":3.4,"publicationDate":"2019-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10852525/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36859216","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Links Between Painting and Neurology: The Example of Dementia. 绘画与神经学之间的联系：以痴呆症为例

IF 3.4 4区医学

American Journal of Alzheimers Disease and Other Dementias Pub Date : 2019-06-01 Epub Date: 2019-01-30 DOI: 10.1177/1533317519826293

Gabriele Cipriani, Luca Cipriani, Sabrina Danti, Lucia Picchi, Mario Di Fiorino

引用次数: 0

Specific Association Between Religiosity and Cognitive Functions in Alzheimer's Disease. 宗教信仰与阿尔茨海默病认知功能之间的特殊关系

IF 3.4 4区医学

American Journal of Alzheimers Disease and Other Dementias Pub Date : 2019-06-01 Epub Date: 2019-01-31 DOI: 10.1177/1533317519827416

JaeHoon Jung, Chang Hyun Lee, Kitack Shin, Daeyoung Roh, Sang-Kyu Lee, Yoo Sun Moon, Duk-In Jon, Do Hoon Kim

{"title":"Specific Association Between Religiosity and Cognitive Functions in Alzheimer's Disease.","authors":"JaeHoon Jung, Chang Hyun Lee, Kitack Shin, Daeyoung Roh, Sang-Kyu Lee, Yoo Sun Moon, Duk-In Jon, Do Hoon Kim","doi":"10.1177/1533317519827416","DOIUrl":"10.1177/1533317519827416","url":null,"abstract":"Objectives: This study aimed to identify the specific relationship between subdomains of religious variables and cognitive functions in outpatients with Alzheimer's disease (AD).Methods: We recruited 325 patients with AD from a psychiatry outpatient clinic. The Korean version of the Consortium to Establish a Registry for Alzheimer's Disease and the Duke University Religion Index were used to assess cognitive functions and religiosity. We performed structural equation modeling and partial correlation analysis after controlling for demographic data.Results: The model in which religiosity beneficially affects cognitive functions showed acceptable model fit (root-mean-square error of approximation = 0.076, Tucker-Lewis index = 0.921, comparative fit index = 0.947). In the partial correlation analysis, organizational religious activity demonstrated positive relationships with memory ( r = 0.144, P = .010), language ( r = 0.149, P = .007), and constructional ability ( r = 0.191 P = .001). Nonorganizational religious activity and intrinsic religiosity were positively associated with memory ( r = 0.115, P = .040; r = 0.140, P = .012) and constructional ability ( r = 0.207, P = .000; r = 0.136, P = .015).Conclusions: The findings suggest that religiosity positively affects cognitive functions and that each religious variable is related differently to the subdomains of cognitive functions in patients with AD.","PeriodicalId":50816,"journal":{"name":"American Journal of Alzheimers Disease and Other Dementias","volume":"34 4","pages":"254-260"},"PeriodicalIF":3.4,"publicationDate":"2019-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10852484/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36915927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0