American Journal of Orthodontics and Dentofacial Orthopedics最新文献

{"title":"Efficacy and adherence of different mandibular advancement devices designs in treatment of obstructive sleep apnea: A systematic review and meta-analysis","authors":"Yanlong Chen ,&nbsp;Jingjing Zhang ,&nbsp;Xuemei Gao ,&nbsp;Fernanda R. Almeida","doi":"10.1016/j.ajodo.2025.01.006","DOIUrl":"10.1016/j.ajodo.2025.01.006","url":null,"abstract":"<div><h3>Introduction</h3><div>This systematic review and meta-analysis aimed to evaluate the efficacy and adherence of different mandibular advancement devices (MADs) designed to treat obstructive sleep apnea, focusing on titratable vs nontitratable and custom-made vs ready-made devices.</div></div><div><h3>Methods</h3><div>Registered with the International Register of Systematic Review (PROSPERO CRD42024557402), a comprehensive literature search was conducted across Ovid MEDLINE, Ovid Embase, and Web of Science up to June 2024. Randomized controlled trials and nonrandomized studies comparing MAD designs were included. The primary outcome was apnea-hypopnea index (AHI) reduction. Secondary outcomes included improvements in Epworth Sleepiness Scale scores, adherence rates, and patient preference. The risk of bias was assessed using the risk-of-bias tool for randomized trials, and the Risk-Of-Bias In Nonrandomized Studies of Intervention tools. Meta-analyses were performed with weighted mean differences (WMD) and 95% confidence intervals (CI).</div></div><div><h3>Results</h3><div>A total of 22 studies were included, comprising 15 randomized controlled trials and 7 nonrandomized studies. Meta-analysis showed significant AHI reduction with both titratable and nontitratable MADs, with no significant difference between groups (WMD: 1.16; 95% CI, −1.29 to 3.61; <em>P</em> = 0.35). Custom-made MADs demonstrated a marginally significantly greater reduction in AHI compared with ready-made MADs (WMD: 1.51; 95% CI, −0.08 to 3.11; <em>P</em> = 0.06). Custom-made MADs also showed higher adherence rates and longer wearing times (WMD: 1.19; 95% CI, 0.65-1.73; <em>P</em> &lt;0.0001) and higher adherence rates.</div></div><div><h3>Conclusions</h3><div>Both titratable and nontitratable MADs, as well as custom-made and ready-made MADs, effectively treated obstructive sleep apnea, with no clear preference for one design over another. Custom-made MADs, however, generally had fewer side effects and offered potential adherence advantages. Further high-quality studies with longer follow-ups are recommended.</div></div>","PeriodicalId":50806,"journal":{"name":"American Journal of Orthodontics and Dentofacial Orthopedics","volume":"167 6","pages":"Pages 635-647.e3"},"PeriodicalIF":2.7,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143587957","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of planned and achieved root angulation changes in teeth adjacent to mandibular premolar extraction sites in patients treated with Invisalign: A retrospective study","authors":"Abirami Thilagalavanian,&nbsp;Tony Weir,&nbsp;Maurice J. Meade","doi":"10.1016/j.ajodo.2025.01.011","DOIUrl":"10.1016/j.ajodo.2025.01.011","url":null,"abstract":"<div><h3>Introduction</h3><div>This study aimed to determine the efficacy of Invisalign (Align Technology, Santa Clara, Calif) in achieving planned root angulation of molars, premolars, and canines adjacent to mandibular premolar extraction sites.</div></div><div><h3>Methods</h3><div>Digital models of adult patients treated with Invisalign aligners and extraction of at least 1 mandibular first (L4) or second (L5) premolar between 2013 and 2019 were evaluated after import into the Geomagic Control X (3D Systems, Rock Hill, SC) metrology platform.</div></div><div><h3>Results</h3><div>Thirty-one patients, comprising 30 L4 and 25 L5 extractions, were assessed. The accuracy of the planned root angular changes ranged from −119.05% to 162.75%. Similar patterns of expression were observed across the L4 and L5 extraction sites. When root tipping away from the extraction site was planned, the overexpression of root movement was likely in the canines and first molars. Underexpression of planned root angulation change was likely in the premolar adjacent to the L4 extraction site, whereas overexpression was more common in a premolar adjacent to a L5 extraction site. No differences in root angulation outcomes related to patient sex, number of prescribed aligners, or attachment type (<em>P</em> &gt;0.05) were observed. A 2-week wear protocol resulted in a significant (<em>P</em> = 0.005) shortfall of 4.52° of root angulation compared with the 1-week wear protocol when crown tipping away from the L5 extraction sites was planned.</div></div><div><h3>Conclusions</h3><div>The root angulation changes in teeth near the mandibular premolar extraction sites did not match those planned. The use of optimized attachments appeared not to improve root angulation outcomes compared with conventional attachments.</div></div>","PeriodicalId":50806,"journal":{"name":"American Journal of Orthodontics and Dentofacial Orthopedics","volume":"167 6","pages":"Pages 681-689"},"PeriodicalIF":2.7,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143606799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Consideration of palatine bone","authors":"Umarevathi Gopalakrishnan","doi":"10.1016/j.ajodo.2025.02.019","DOIUrl":"10.1016/j.ajodo.2025.02.019","url":null,"abstract":"","PeriodicalId":50806,"journal":{"name":"American Journal of Orthodontics and Dentofacial Orthopedics","volume":"167 6","pages":"Page 626"},"PeriodicalIF":2.7,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144195049","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corrigendum to ‘Association between nasal septum deviation and transverse maxillary development: A retrospective cross-sectional study’ American Journal of Orthodontics and Dentofacial Orthopedics, Volume 164, Issue 4, October 2023, Pages 575-583","authors":"Nannapat Jongkhum ,&nbsp;Raweewan Arayasantiparb ,&nbsp;Supatchai Boonpratham ,&nbsp;Nuntinee Nanthavanich Saengfai ,&nbsp;Chaiyapol Chaweewannakorn ,&nbsp;Yodhathai Satravaha ,&nbsp;Supakit Peanchitlertkajorn","doi":"10.1016/j.ajodo.2025.03.006","DOIUrl":"10.1016/j.ajodo.2025.03.006","url":null,"abstract":"","PeriodicalId":50806,"journal":{"name":"American Journal of Orthodontics and Dentofacial Orthopedics","volume":"167 6","pages":"Page 627"},"PeriodicalIF":2.7,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144195016","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Great expectations","authors":"Peter M. Greco","doi":"10.1016/j.ajodo.2025.03.001","DOIUrl":"10.1016/j.ajodo.2025.03.001","url":null,"abstract":"","PeriodicalId":50806,"journal":{"name":"American Journal of Orthodontics and Dentofacial Orthopedics","volume":"167 6","pages":"Page 628"},"PeriodicalIF":2.7,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144195017","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mouth breathing and orthodontic intervention: Does the evidence support keeping our mouths shut?","authors":"Sanjivan Kandasamy","doi":"10.1016/j.ajodo.2025.02.005","DOIUrl":"10.1016/j.ajodo.2025.02.005","url":null,"abstract":"<div><div>It is believed that mouth breathing, particularly during early childhood, is associated with the development of various unfavorable craniofacial characteristics such as mandibular retrognathia, narrow high arch palates and alar bases, lip incompetence, increased vertical facial height, and mandibular plane angles. Today, there is significant debate and confusion pertaining to the role of orthodontists in identifying and managing mouth breathing, especially for young patients as early as 3 years old. Using the historical and contemporary evidence-based literature along with an ethical and pragmatic clinical perspective, the role of mouth breathing and early orthodontic intervention is put into perspective in this paper.</div></div>","PeriodicalId":50806,"journal":{"name":"American Journal of Orthodontics and Dentofacial Orthopedics","volume":"167 6","pages":"Pages 629-634"},"PeriodicalIF":2.7,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143587961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Regrets, I’ve had a few…","authors":"Laurance Jerrold","doi":"10.1016/j.ajodo.2025.03.002","DOIUrl":"10.1016/j.ajodo.2025.03.002","url":null,"abstract":"","PeriodicalId":50806,"journal":{"name":"American Journal of Orthodontics and Dentofacial Orthopedics","volume":"167 6","pages":"Pages 741-744"},"PeriodicalIF":2.7,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144194604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A bright future for the American Journal of Orthodontics and Dentofacial Orthopedics and the American Journal of Orthodontics and Dentofacial Orthopedics Clinical Companion","authors":"Jae Hyun Park","doi":"10.1016/j.ajodo.2025.03.005","DOIUrl":"10.1016/j.ajodo.2025.03.005","url":null,"abstract":"","PeriodicalId":50806,"journal":{"name":"American Journal of Orthodontics and Dentofacial Orthopedics","volume":"167 6","pages":"Pages 623-625"},"PeriodicalIF":2.7,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144194904","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"June 2025","authors":"Dr Allen H. Moffitt (CE Editor)","doi":"10.1016/j.ajodo.2025.04.006","DOIUrl":"10.1016/j.ajodo.2025.04.006","url":null,"abstract":"","PeriodicalId":50806,"journal":{"name":"American Journal of Orthodontics and Dentofacial Orthopedics","volume":"167 6","pages":"Pages 745.e1-745.e2"},"PeriodicalIF":2.7,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144194605","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Investigation of the cytotoxic and genotoxic effects of removable retention appliances","authors":"Rukiye Gunel ,&nbsp;Ayşegul Gulec ,&nbsp;Seyithan Taysi ,&nbsp;Evren Uzun","doi":"10.1016/j.ajodo.2025.01.013","DOIUrl":"10.1016/j.ajodo.2025.01.013","url":null,"abstract":"<div><h3>Introduction</h3><div>This study aimed to examine and compare the cytotoxic and genotoxic effects of Hawley and Essix removable retainers on tissues.</div></div><div><h3>Methods</h3><div>A total of 50 patients who had completed fixed orthodontic treatment were randomly assigned to 1 of 2 groups based on the type of retainer they would use for retention: Essix group (n = 25) or Hawley group (n = 25). For biochemical evaluation, saliva samples were collected at 3-time points: before appliance use, 1 month after appliance use (TB1), and 3 months after appliance use. The levels of 8-hydroxy-2'-deoxyguanosine (8-OHdG), nuclear factor erythroid 2-related factor 2, and Kelch-like ECH-related protein 1 (Keap1) were then analyzed. For cytologic evaluation, swab samples were collected before and 14-21 days after the use of the appliance, and the occurrence of micronucleus, pyknosis, karyorrhexis, and karyolysis were analyzed.</div></div><div><h3>Results</h3><div>Biochemical evaluation revealed that the 8-OHdG level was higher in the Hawley group at TB1 and TB2. Conversely, no significant differences were observed in nuclear factor erythroid 2-related factor 2 levels between the groups. Although no significant difference in Keap1 value was observed between the 2 groups at TB1, a notable elevation in Keap1 levels was evident in the Hawley group at TB2. A cytologic evaluation revealed that the levels of micronuclei, pyknosis, karyorrhexis, and karyolysis were higher in the Essix group at 14-21 days after appliance use.</div></div><div><h3>Conclusions</h3><div>The application of both appliances was observed to increase the number of findings indicating nuclear degeneration. However, the Hawley retainer increased the 8-OHdG level, whereas the Essix retainer showed a decrease in this 8-OHdG level.</div></div>","PeriodicalId":50806,"journal":{"name":"American Journal of Orthodontics and Dentofacial Orthopedics","volume":"167 6","pages":"Pages 703-712"},"PeriodicalIF":2.7,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143525128","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}