American Journal of Orthodontics and Dentofacial Orthopedics最新文献

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Courtesy counts 礼貌计数
IF 2.7 2区 医学
American Journal of Orthodontics and Dentofacial Orthopedics Pub Date : 2025-03-27 DOI: 10.1016/j.ajodo.2025.01.001
Peter M. Greco
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引用次数: 0
Who gets to vote on what? 谁对什么投票?
IF 2.7 2区 医学
American Journal of Orthodontics and Dentofacial Orthopedics Pub Date : 2025-03-27 DOI: 10.1016/j.ajodo.2025.01.002
Laurance Jerrold
{"title":"Who gets to vote on what?","authors":"Laurance Jerrold","doi":"10.1016/j.ajodo.2025.01.002","DOIUrl":"10.1016/j.ajodo.2025.01.002","url":null,"abstract":"","PeriodicalId":50806,"journal":{"name":"American Journal of Orthodontics and Dentofacial Orthopedics","volume":"167 4","pages":"Pages 499-501"},"PeriodicalIF":2.7,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143714518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Directory: AAO Officers and Organizations 目录:AAO官员和组织
IF 2.7 2区 医学
American Journal of Orthodontics and Dentofacial Orthopedics Pub Date : 2025-03-27 DOI: 10.1016/S0889-5406(25)00089-7
{"title":"Directory: AAO Officers and Organizations","authors":"","doi":"10.1016/S0889-5406(25)00089-7","DOIUrl":"10.1016/S0889-5406(25)00089-7","url":null,"abstract":"","PeriodicalId":50806,"journal":{"name":"American Journal of Orthodontics and Dentofacial Orthopedics","volume":"167 4","pages":"Page 503"},"PeriodicalIF":2.7,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143715026","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The American Board of Orthodontics: Written examination development, modification, and preparation recommendations. 美国正畸委员会:笔试发展、修改和准备建议。
IF 2.7 2区 医学
American Journal of Orthodontics and Dentofacial Orthopedics Pub Date : 2025-03-26 DOI: 10.1016/j.ajodo.2025.02.008
Jae Hyun Park, Roberto Hernandez-Orsini, Paul Emile Rossouw, Anthony M Puntillo, Daniel J Rejman, Meenakshi Vishwanath, Onur Kadioglu, Timothy Tremont, Timothy S Trulove
{"title":"The American Board of Orthodontics: Written examination development, modification, and preparation recommendations.","authors":"Jae Hyun Park, Roberto Hernandez-Orsini, Paul Emile Rossouw, Anthony M Puntillo, Daniel J Rejman, Meenakshi Vishwanath, Onur Kadioglu, Timothy Tremont, Timothy S Trulove","doi":"10.1016/j.ajodo.2025.02.008","DOIUrl":"https://doi.org/10.1016/j.ajodo.2025.02.008","url":null,"abstract":"<p><p>This article outlines the process of developing a written examination by the American Board of Orthodontics (ABO). It is a 240-question comprehensive examination that assesses the examinee's knowledge of basic sciences and clinical concepts based on criterion-referenced testing. Examinees' skills and knowledge are measured against the set of information represented by each test item. In addition, the ABO now offers both virtual and live presentations through \"The Pathway Program\" to further support examination preparation. For more information, please visit the ABO's official Website at AmericanBoardOrtho.com.</p>","PeriodicalId":50806,"journal":{"name":"American Journal of Orthodontics and Dentofacial Orthopedics","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143722574","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Estimation of centers of rotation of the maxillary incisors during nonextraction space closure using the Invisalign appliance. 使用Invisalign矫治器在非拔牙间隙闭合时上颌切牙旋转中心的估计。
IF 2.7 2区 医学
American Journal of Orthodontics and Dentofacial Orthopedics Pub Date : 2025-03-25 DOI: 10.1016/j.ajodo.2025.02.012
Darshan N Desai, Tony Weir, Maurice J Meade
{"title":"Estimation of centers of rotation of the maxillary incisors during nonextraction space closure using the Invisalign appliance.","authors":"Darshan N Desai, Tony Weir, Maurice J Meade","doi":"10.1016/j.ajodo.2025.02.012","DOIUrl":"https://doi.org/10.1016/j.ajodo.2025.02.012","url":null,"abstract":"<p><strong>Introduction: </strong>The primary objective was to establish the center of rotation of maxillary incisors during nonextraction space closure with a series of Invisalign aligners (Align Technology, Santa Clara, Calif) and to determine the accuracy of planned orthodontic tooth movement (OTM). The secondary objective was to investigate the efficacy of achieving labiolingual incisor angulation changes planned before the commencement of treatment.</p><p><strong>Methods: </strong>Digital models representing the pretreatment (T0), planned treatment (T1), and achieved treatment occlusion (T2) were superimposed and analyzed using the Geomagic Control X (version 2022.0; 3D Systems, Rock Hill, NC) software platform. Three-dimensional vector analogs for the long axes of the teeth were generated, and their intersection determined the center of rotation at T1 and T2. The angle formed by the vectors to the y-axis Cartesian plane represented the incisors' labiolingual angulations at the 3-time points.</p><p><strong>Results: </strong>A total of 240 maxillary incisors in 60 patients were assessed. The mean (standard deviation) accuracy of achieving the planned OTM for maxillary incisors ranged from 33.2% (31.8) to 35.4% (25.2). Uncontrolled tipping was the most accurate OTM, achieving 76% accuracy for central and 60% for lateral incisors. During the labiolingual incisor change, the planned incisor retroclination was overexpressed by 169% for central and 126% for lateral incisors. Planned incisor proclination was inefficacious, with 10.7% of central and 43.5% of lateral incisors proclining as planned.</p><p><strong>Conclusions: </strong>Approximately one-third of the planned OTM for maxillary incisors after nonextraction space closure was achieved. Planned maxillary incisor retroclination was overexpressed, and most incisors retroclined during planned proclination.</p>","PeriodicalId":50806,"journal":{"name":"American Journal of Orthodontics and Dentofacial Orthopedics","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143702132","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Craniofacial and atlas vertebra structures in patients with maxillary palatally displaced canines: A cone-beam computed tomography-based retrospective study. 上颌腭移位犬的颅面和寰椎结构:一项基于锥束计算机断层扫描的回顾性研究。
IF 2.7 2区 医学
American Journal of Orthodontics and Dentofacial Orthopedics Pub Date : 2025-03-25 DOI: 10.1016/j.ajodo.2025.02.016
Chi Liao, Xinyi Fang, Yanmei Huang, Hanqi Fu, Jiu Lin, Qianming Chen, Xiaoyan Chen
{"title":"Craniofacial and atlas vertebra structures in patients with maxillary palatally displaced canines: A cone-beam computed tomography-based retrospective study.","authors":"Chi Liao, Xinyi Fang, Yanmei Huang, Hanqi Fu, Jiu Lin, Qianming Chen, Xiaoyan Chen","doi":"10.1016/j.ajodo.2025.02.016","DOIUrl":"10.1016/j.ajodo.2025.02.016","url":null,"abstract":"<p><strong>Introduction: </strong>This retrospective cone-beam computed tomography (CBCT) study aimed to analyze the associations between maxillary palatally displaced canine (PDC) with the craniofacial and atlas vertebra structures.</p><p><strong>Methods: </strong>A total of 94 patients (47 with PDC and 47 normal) were included. Then, their CBCT data were reconstructed and analyzed to measure the 3-dimensional angular positions of canines, the structures of sella turcica, atlas vertebra, and cranial base. Comparisons of continuous variables between 2 groups were performed using the independent samples t test or the Mann-Whitney U test, whereas 1-way analysis of variance or Kruskal-Wallis tests were used for comparisons among multiple groups. Categorical variables were compared using the chi-square test or Fisher exact test, as appropriate. Binary logistic regression analyses, along with Spearman or Pearson correlation analyses, were conducted to determine the associations between variables.</p><p><strong>Results: </strong>No significant differences were observed in sella turcica structures or the occurrence of ponticulus posticus between the 2 groups (P >0.05). The anterior cranial base length was significantly smaller, and the cranial base angle was significantly larger in subjects with PDC (P <0.05). Moreover, a significant negative correlation was identified between anterior cranial base length and the occurrence of PDC (P <0.05). However, the angular positions of canines showed no significant correlation with any craniofacial variables.</p><p><strong>Conclusions: </strong>On the basis of CBCT data, the structures of sella turcica and atlas vertebra did not differ between patients with PDC and those with normally erupted canines. However, patients with PDC exhibited a significantly shorter anterior cranial base length and a greater cranial base angle, suggesting a possible developmental link between cranial base morphology and maxillary canines. The explicit relationship and clinical significance of PDC with craniofacial structures require further investigation.</p>","PeriodicalId":50806,"journal":{"name":"American Journal of Orthodontics and Dentofacial Orthopedics","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143702131","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Changes in alveolar bone remodeling after maxillary anterior retraction using fixed appliances with different periodontal conditions: A retrospective study based on cone-beam computed tomography. 不同牙周条件下固定矫治器上颌前牙后牙槽骨重塑的变化:一项基于锥束计算机断层扫描的回顾性研究。
IF 2.7 2区 医学
American Journal of Orthodontics and Dentofacial Orthopedics Pub Date : 2025-03-22 DOI: 10.1016/j.ajodo.2025.02.013
Yao Li, Jiaxin Huang, Zixin Fan, Minxuan Han, Yan Gu, Dandan Li, Yuan Li, Lu Li
{"title":"Changes in alveolar bone remodeling after maxillary anterior retraction using fixed appliances with different periodontal conditions: A retrospective study based on cone-beam computed tomography.","authors":"Yao Li, Jiaxin Huang, Zixin Fan, Minxuan Han, Yan Gu, Dandan Li, Yuan Li, Lu Li","doi":"10.1016/j.ajodo.2025.02.013","DOIUrl":"https://doi.org/10.1016/j.ajodo.2025.02.013","url":null,"abstract":"<p><strong>Introduction: </strong>This study aimed to compare changes in maxillary anterior alveolar bone remodeling and complication rates in adult patients with different periodontal conditions after maxillary anterior tooth retraction using fixed appliances. In addition, this study analyzed potential factors affecting alveolar bone thickness in patients with periodontitis.</p><p><strong>Methods: </strong>A total of 55 adult patients (mean age, 23.53 ± 4.55 years) with Angle Class I or II Division 1 malocclusion with maxillary protrusion were recruited and categorized into the healthy control group (n = 23), stage I periodontitis (P-I) group (n = 17), and stage II periodontitis (P-II) group (n = 15). The maxillary anterior teeth were retracted using a fixed appliance. Cone-beam computed tomography was used to measure the thickness, height, and density of the alveolar bone in the maxillary anterior region before (T1) and after (T2) treatment. The incidences of bone dehiscence and fenestration were documented. Statistical analysis was conducted to evaluate intergroup and intragroup differences. Clinical and cephalometric data were collected to identify factors affecting the changes in alveolar bone thickness using multivariate linear regression analysis.</p><p><strong>Results: </strong>The labial alveolar bone thickness increased significantly after treatment in all groups, but no differences were observed among the groups. In contrast, the palatal alveolar bone thickness decreased, particularly in the P-I and P-II groups, at the midroot and apical levels (P <0.05). A significant decrease in alveolar bone height was observed in the P-I and P-II groups (P <0.05). The incidence of palatal bone dehiscence was higher in the P-II (84.44%) and P-I (69.61%) groups. Multivariate linear regression analyses revealed that sex, treatment duration, periodontal treatment, changes in tooth inclination, and initial thickness significantly affected palatal alveolar bone thickness changes in patients with periodontitis.</p><p><strong>Conclusions: </strong>After retraction of the maxillary anterior teeth with a fixed appliance, the labial alveolar bone of the maxillary anterior teeth thickened, whereas the palatal bone exhibited thinning in adults with periodontitis. The reduction in palatal bone height was more significant in this population than in healthy subjects, along with a higher incidence of palatal bone dehiscence. Bone morphology must be carefully assessed, considering these relevant factors before and during orthodontic treatment.</p>","PeriodicalId":50806,"journal":{"name":"American Journal of Orthodontics and Dentofacial Orthopedics","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143677304","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Predictability of incisal labiolingual inclination, overjet, and overbite changes, and the prevalence of open gingival embrasures in patients with mandibular incisor extraction treated with Invisalign: A retrospective cohort study. 一项回顾性队列研究:使用Invisalign治疗的下颌切牙拔牙患者的切唇舌倾斜、覆盖和覆盖改变的可预测性以及开放牙龈囊膜的患病率。
IF 2.7 2区 医学
American Journal of Orthodontics and Dentofacial Orthopedics Pub Date : 2025-03-22 DOI: 10.1016/j.ajodo.2025.02.015
Keith Chan, Tony Weir, Elissa Freer, Desmond Ong, Hien Nguyen
{"title":"Predictability of incisal labiolingual inclination, overjet, and overbite changes, and the prevalence of open gingival embrasures in patients with mandibular incisor extraction treated with Invisalign: A retrospective cohort study.","authors":"Keith Chan, Tony Weir, Elissa Freer, Desmond Ong, Hien Nguyen","doi":"10.1016/j.ajodo.2025.02.015","DOIUrl":"https://doi.org/10.1016/j.ajodo.2025.02.015","url":null,"abstract":"<p><strong>Introduction: </strong>This retrospective study aimed to assess differences between the planned Invisalign (Align Technology, San Jose, Calif) ClinCheck tooth movements and the achieved outcomes for patients with single mandibular incisor extraction with respect to overjet, overbite, and labiolingual inclination for the initial series of aligners and to assess the prevalence of open gingival embrasures (OGEs) in the former extraction sites.</p><p><strong>Methods: </strong>The records of 83 patients who received Invisalign treatment with extraction of a single mandibular incisor were evaluated. The predicted and achieved overjet and overbite measurements were compared using the Invisalign ClinCheck software. The prevalence of an OGE was assessed visually using posttreatment digital models. The labiolingual inclination of the mandibular incisors was measured through superimposition of the pretreatment, predicted posttreatment, and achieved posttreatment digital models using Geomagic Control X (version 2018 1.0; 3D Systems, Rock Hill, SC) metrology software.</p><p><strong>Results: </strong>Differences between predicted and achieved labiolingual inclination changes of the mandibular incisors were minor in the lingual direction (90.4%); however, planned labial movements were significantly underexpressed (59.0%). A comparison of the predicted and achieved overjet values revealed a clinical expression of 49.6% and 76.0% when the overjet was planned to decrease and increase, respectively. With respect to the predicted and achieved overbite changes, no significant difference was found when the overbite was predicted to increase. In contrast, when the overbite was predicted to decrease, only 50.5% of this planned overbite reduction was clinically achieved. Most patients (95.2%) displayed an OGE in the former extraction space.</p><p><strong>Conclusions: </strong>Extraction of a single mandibular incisor in conjunction with Invisalign treatment resulted in an underexpression of the predicted proclination of the mandibular incisors, overjet changes, and overbite reduction. The development of an OGE was highly probable after the initial CAT aligner series.</p>","PeriodicalId":50806,"journal":{"name":"American Journal of Orthodontics and Dentofacial Orthopedics","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143677271","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of a multifunctional orthodontic adhesive incorporating zinc oxide quantum dots. 评估含有氧化锌量子点的多功能正畸粘合剂。
IF 2.7 2区 医学
American Journal of Orthodontics and Dentofacial Orthopedics Pub Date : 2025-03-21 DOI: 10.1016/j.ajodo.2025.02.011
Jiarong Yan, Yun Zhu, Ting Luo, Xiaozhu Liao, Xuepeng Chen, Fang Hua, Hong He
{"title":"Evaluation of a multifunctional orthodontic adhesive incorporating zinc oxide quantum dots.","authors":"Jiarong Yan, Yun Zhu, Ting Luo, Xiaozhu Liao, Xuepeng Chen, Fang Hua, Hong He","doi":"10.1016/j.ajodo.2025.02.011","DOIUrl":"https://doi.org/10.1016/j.ajodo.2025.02.011","url":null,"abstract":"<p><strong>Introduction: </strong>The objective of this study was to further evaluate the long-term antibiofilm and fluorescence properties as well as enamel demineralization prevention ability, removal efficiency, and biocompatibility of an orthodontic adhesive modified with zinc oxide quantum dots (ZnQDs).</p><p><strong>Methods: </strong>ZnQDs were synthesized and characterized by transmission electron microscope and fluorescence observation. Minimal inhibitory concentration and minimum bactericidal concentration of ZnQDs against Streptococcus mutans were evaluated. ZnQDs (20% by weight) were incorporated into Transbond XT adhesive paste to form the multifunctional orthodontic adhesive (quantum dots adhesive 20 [QDA20]). Long-term antibiofilm capability and fluorescence properties were evaluated after saliva storage aging. A biofilm demineralization model was constructed, and the enamel demineralization degree was evaluated by color analysis, Raman analysis and microcomputed tomography. Bracket bonding and debonding procedures were performed on a head simulator, and the effectiveness of adhesive removal was assessed. Subcutaneous tissue, blood, and organ compatibility assays were performed on a rat subcutaneous tissue implant model.</p><p><strong>Results: </strong>ZnQDs had a diameter of approximately 5 nm, and the minimal inhibitory concentration and minimum bactericidal concentration against S mutans were 0.32 and 1.25 mg/mL. ZnQDs showed long-lasting antibiofilm and fluorescent properties and could reduce the color change and mineral loss of enamel during the biofilm demineralization process. On the head simulator, QDA20 could help the operator remove adhesive more thoroughly without damaging enamel. Histologic analysis of subcutaneous tissue and organs, and blood analysis proved that QDA20 was well-biocompatible.</p><p><strong>Conclusions: </strong>ZnQDs showed excellent antibiofilm and fluorescent properties and thus could be a multifunctional adhesive to overcome the 2 major challenges of enamel demineralization and difficulty in recognizing adhesives during fixed orthodontic treatment.</p>","PeriodicalId":50806,"journal":{"name":"American Journal of Orthodontics and Dentofacial Orthopedics","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143677306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effectiveness of nasoalveolar molding treatment for babies with nonsyndromic complete unilateral cleft lip, alveolus, and palate: A systematic review and meta-analysis. 鼻肺泡成型治疗婴儿无综合征完全性单侧唇裂、肺泡和腭裂的有效性:一项系统回顾和荟萃分析。
IF 2.7 2区 医学
American Journal of Orthodontics and Dentofacial Orthopedics Pub Date : 2025-03-19 DOI: 10.1016/j.ajodo.2025.01.012
Badri Thiruvenkatachari, Subhiksha Chakkaravarthi, Aarthi Bhuvaraghan
{"title":"Effectiveness of nasoalveolar molding treatment for babies with nonsyndromic complete unilateral cleft lip, alveolus, and palate: A systematic review and meta-analysis.","authors":"Badri Thiruvenkatachari, Subhiksha Chakkaravarthi, Aarthi Bhuvaraghan","doi":"10.1016/j.ajodo.2025.01.012","DOIUrl":"https://doi.org/10.1016/j.ajodo.2025.01.012","url":null,"abstract":"<p><strong>Introduction: </strong>This systematic review aimed to compare the effectiveness of nasoalveolar molding (NAM) treatment with no NAM group for babies with nonsyndromic unilateral cleft lip, alveolus, and palate.</p><p><strong>Methods: </strong>All relevant studies from 1946 to February 2024 were identified using several sources, including The Cochrane Database of Systematic Reviews, Cochrane Central Register of Controlled Trials, LILACS, Scopus, EMBASE, MEDLINE (Ovid), and ePUB ahead of publications and nonindexed citations. The criteria for this review were as follows: (1) studies with a randomized controlled trial (RCT) and controlled clinical trial (CCT) design; (2) the target population included patients with nonsyndromic complete unilateral cleft lip, alveolus, and palate; (3) the intervention group received NAM treatment before lip repair, whereas the comparison group did not; and (4) the primary outcome was nasolabial esthetics measured using Asher McDade index. All articles were screened for the title, abstract, and full text independently and in duplicate by 2 reviewers. The quality assessment of RCT was performed using Cochrane's risk of bias tool, and the CCT was assessed using the Risk Of Bias In Nonrandomized Studies of Interventions tool.</p><p><strong>Results: </strong>Out of the 1432 studies retrieved, 2 RCTs and 3 CCTs were included. One RCT was assessed as having a high risk of bias, whereas the other had an unclear risk. All included CCTs were rated as having a high risk of bias. The studies showed a statistically significant reduction in cleft width favoring the NAM group, and 1 study with a high risk of bias reported significantly better long-term intercanine width for NAM. However, none of the included studies examined long-term or short-term nasolabial esthetics or other functional or esthetic outcomes over the long term.</p><p><strong>Conclusions: </strong>No conclusions can be drawn on the nasolabial esthetics as none of the included studies evaluated this primary outcome in the short or long term. There is low certainty of evidence supporting the short-term effectiveness of NAM for cleft width reduction in patients with complete unilateral cleft lip, alveolus, and palate. Further high-quality studies are needed to evaluate the long-term effectiveness of NAM treatment, enabling clinicians and patients to make informed decisions.</p><p><strong>Registration: </strong>The protocol for the systematic review was registered with the International Prospective Register of Systematic Reviews from the National Institute for Health Research database (Prospero No. CRD42024503388).</p><p><strong>Funding: </strong>This work was supported by the DBT/Wellcome Trust India Alliance Grant (No. IA/CPHS/20/1/505255; awarded to Badri Thiruvenkatachari).</p>","PeriodicalId":50806,"journal":{"name":"American Journal of Orthodontics and Dentofacial Orthopedics","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143674722","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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