Annals of Allergy Asthma & Immunology最新文献

{"title":"Managing Anaphylaxis in Patients on Beta-Blockers: Case Insights and Practical Considerations.","authors":"Dayna Miyashiro, Edsel M Abud, Kevin A Cook, Andrew A White","doi":"10.1016/j.anai.2025.06.031","DOIUrl":"https://doi.org/10.1016/j.anai.2025.06.031","url":null,"abstract":"","PeriodicalId":50773,"journal":{"name":"Annals of Allergy Asthma & Immunology","volume":" ","pages":""},"PeriodicalIF":5.8,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144602170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"One-Bag Protocol for Cancer Drug Hypersensitivity: A Meta-Analysis of Safety and Effectiveness.","authors":"Andrés Noyola-Perez, Sandra N González-Diaz, Carlos Macouzet-Sánchez, Jesús M Alanís-Alvarez, Valeria Muñoz-Silva, Rosa I Guzmán-Avilán, Alejandra Macias-Weinmann, Cindy E De Lira-Quezada, Natalhie Acuña-Ortega, Mário Morais-Almeida, Ignacio J Ansotegui","doi":"10.1016/j.anai.2025.06.034","DOIUrl":"https://doi.org/10.1016/j.anai.2025.06.034","url":null,"abstract":"<p><strong>Background: </strong>Hypersensitivity reactions (HSRs) to essential chemotherapy create treatment barriers in cancer care globally. Conventional three-bag protocols (3BP) for rapid drug desensitization (RDD) present operational challenges that may inadvertently exacerbate healthcare disparities.</p><p><strong>Objective: </strong>We aimed to systematically evaluate the safety, completion rates, and procedural duration of 1BP for chemotherapy and monoclonal antibody HSRs, and to compare these outcomes with those of conventional 3BP.</p><p><strong>Methods: </strong>In this meta-analysis, we searched MEDLINE, Embase, Web of Science, and CENTRAL. We included studies describing 1BP for HSRs to chemotherapy and monoclonal antibodies. Four reviewers independently screened the studies and extracted the data. The primary outcome was the pooled completion rate of the 1BP protocols. Secondary outcomes compared safety, completion rates, and protocol duration between the 1BP and 3BP.</p><p><strong>Results: </strong>Our analysis of 16 studies included 975 patients undergoing 4,473 RDD procedures. The pooled completion rate for 1BP was 99.7% (95% CI: 99.35-99.9%; Prediction Interval: 98-100%), remaining consistent across drug classes. While BTR occurred in 12% of RDDs, they were predominantly mild to moderate, with only 0.4% being severe. In studies comparing protocols, there was no significant difference in completion rates (Risk Difference: 0.00; p = 0.966).</p><p><strong>Conclusion: </strong>One-bag RDD protocols demonstrate demonstrate consistent safety and completion rates. Our findings suggest that patient safety relies on the precise control of exposure kinetics rather than multiple dilution steps. By reducing procedural complexity and duration, 1BP provides a robust strategy to streamline workflows, optimize resource allocation, and enhance patient access to cancer therapies across diverse healthcare settings.</p><p><strong>Prospero registration: </strong>CRD42024586580.</p>","PeriodicalId":50773,"journal":{"name":"Annals of Allergy Asthma & Immunology","volume":" ","pages":""},"PeriodicalIF":5.8,"publicationDate":"2025-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144585544","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Severe asthma and new-onset meat allergy in a child-could a new puppy be to blame?","authors":"Gauri Misra, Rebecca Grohman, Mikhail Kazachkov, Anna Nowak-Wegrzyn","doi":"10.1016/j.anai.2025.06.033","DOIUrl":"https://doi.org/10.1016/j.anai.2025.06.033","url":null,"abstract":"","PeriodicalId":50773,"journal":{"name":"Annals of Allergy Asthma & Immunology","volume":" ","pages":""},"PeriodicalIF":5.8,"publicationDate":"2025-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144565445","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Management of indolent mastocytosis and mast cell activation syndrome: A clinical yardstick.","authors":"Cem Akin, Joseph H Butterfield, Mariana Castells, Jonathan J Lyons, Jay Lieberman","doi":"10.1016/j.anai.2025.06.032","DOIUrl":"https://doi.org/10.1016/j.anai.2025.06.032","url":null,"abstract":"<p><p>Knowledge and understanding of mast cell biology and mast cell disorders has increased in the past several years, with new classifications of diseases for both clonal and non-clonal forms. Along with these classifications has come differing treatment paradigms, including novel therapies now approved for various forms of clonal mast cell disorders. Unfortunately, there is some lack of guidance on how best to utilize these therapies. This yardstick aims to provide the clinician with a review of available therapies to treat mast cell activation syndrome and indolent systemic mastocytosis and an evidence-based expert opinion approach regarding how best to utilize these therapies.</p>","PeriodicalId":50773,"journal":{"name":"Annals of Allergy Asthma & Immunology","volume":" ","pages":""},"PeriodicalIF":5.8,"publicationDate":"2025-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144545927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Treating allergic rhinitis by thinking globally and acting locally","authors":"Marcus Shaker MD, MS ,&nbsp;Larry Borish MD","doi":"10.1016/j.anai.2025.03.024","DOIUrl":"10.1016/j.anai.2025.03.024","url":null,"abstract":"","PeriodicalId":50773,"journal":{"name":"Annals of Allergy Asthma & Immunology","volume":"135 1","pages":"Pages 1-2"},"PeriodicalIF":5.8,"publicationDate":"2025-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144480606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Weighing real-world studies when choosing a biologic for asthma","authors":"Suzanne Y. Ngo MD ,&nbsp;William C. Anderson III MD","doi":"10.1016/j.anai.2025.04.004","DOIUrl":"10.1016/j.anai.2025.04.004","url":null,"abstract":"","PeriodicalId":50773,"journal":{"name":"Annals of Allergy Asthma & Immunology","volume":"135 1","pages":"Pages 11-12"},"PeriodicalIF":5.8,"publicationDate":"2025-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144480761","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"From the pages of AllergyWatch","authors":"Stanley M. Fineman MD ,&nbsp;Shyam R. Joshi MD ,&nbsp;Iris Otani MD ,&nbsp;Sarah Spriet DO","doi":"10.1016/j.anai.2025.02.006","DOIUrl":"10.1016/j.anai.2025.02.006","url":null,"abstract":"","PeriodicalId":50773,"journal":{"name":"Annals of Allergy Asthma & Immunology","volume":"135 1","pages":"Pages 122-123"},"PeriodicalIF":5.8,"publicationDate":"2025-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144481043","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Information for Readers","authors":"","doi":"10.1016/S1081-1206(25)00254-6","DOIUrl":"10.1016/S1081-1206(25)00254-6","url":null,"abstract":"","PeriodicalId":50773,"journal":{"name":"Annals of Allergy Asthma & Immunology","volume":"135 1","pages":"Page A5"},"PeriodicalIF":5.8,"publicationDate":"2025-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144480603","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Incorporating Type-2 inflammation status with clinical diagnosis and transcriptomics data in asthma risk classification.","authors":"Zi Ye, Solomon W Harrar, Joseph Beyene, Tesfaye B Mersha","doi":"10.1016/j.anai.2025.06.029","DOIUrl":"https://doi.org/10.1016/j.anai.2025.06.029","url":null,"abstract":"<p><p>bronchial hyperresponsiveness (BHR), Immunoglobulin (IgE), skin prick test (SPT), T helper 2 (Th2), interleukin (IL), Type 2 inflammation (Th2), Area Under the Curve (AUC), Receiver Operating Characteristic (ROC), Genes-Environments and Admixture in Latino Americans (GALA II).</p>","PeriodicalId":50773,"journal":{"name":"Annals of Allergy Asthma & Immunology","volume":" ","pages":""},"PeriodicalIF":5.8,"publicationDate":"2025-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144530915","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Identifying patients with uncontrolled asthma or severe asthma","authors":"Jerrius Jubran DO ,&nbsp;Jonathan S. Tam MD","doi":"10.1016/j.anai.2025.05.002","DOIUrl":"10.1016/j.anai.2025.05.002","url":null,"abstract":"","PeriodicalId":50773,"journal":{"name":"Annals of Allergy Asthma & Immunology","volume":"135 1","pages":"Pages 13-14"},"PeriodicalIF":5.8,"publicationDate":"2025-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144480762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}