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Analysis of Shannon's entropy to contrast between the Embodied and Neurocentrist hypothesis of conscious experience 分析香农熵,对比意识体验的 "体现 "假说和 "神经中心 "假说。
IF 2 4区 生物学
Biosystems Pub Date : 2024-09-05 DOI: 10.1016/j.biosystems.2024.105323
Sergio J. Martínez García , Pablo Padilla Longoria
{"title":"Analysis of Shannon's entropy to contrast between the Embodied and Neurocentrist hypothesis of conscious experience","authors":"Sergio J. Martínez García ,&nbsp;Pablo Padilla Longoria","doi":"10.1016/j.biosystems.2024.105323","DOIUrl":"10.1016/j.biosystems.2024.105323","url":null,"abstract":"<div><p>We usually accept that consciousness is in the brain. This statement corresponds to a Neurocentrist view. However, with all the physical and physiological data currently available, a convincing explanation of how consciousness emerges has not been given this topic is aborded by Anil Seth (2021). Because of this, a natural question arises: Is consciousness really in the brain or not? If the answer is no, this corresponds to the Embodied perspective. We cannot discriminate between these two points of view because we cannot identify how the organism processes the information. If we try to measure information processing in the brain, then the Neurocentrist view is unavoidable. For example, the information integration theory of Tononi's research group and the global work area theory developed by Dehaene and Baars, focus solely on the brain without considering aspects of Embodied vision (See Tononi, 2021; Dehaene, 2021). In this article, we propose an index based on Shannon's entropy, capable of identifying the leading processing elements acting: Are they mainly inner or external? In order to validate it, we performed simulations with networks accounting for different amounts of internal and outer layers. Since Shannon's entropy is an abstract measure of the information content, this index is not dependent on the physical network nor the proportion of different layers. Therefore, we validate the index as free of bias. This index is a way to discriminate between Embodied from Neurocentrist hypotheses.</p></div>","PeriodicalId":50730,"journal":{"name":"Biosystems","volume":"246 ","pages":"Article 105323"},"PeriodicalIF":2.0,"publicationDate":"2024-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0303264724002089/pdfft?md5=b544a42da3972658aba1832fc0bd50c7&pid=1-s2.0-S0303264724002089-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142146786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
In search for evolutionary roots of a mindful cognition: A Darwinian view on sustained intentional awareness 寻找心智认知的进化根源:关于持续有意识的达尔文观点。
IF 2 4区 生物学
Biosystems Pub Date : 2024-09-02 DOI: 10.1016/j.biosystems.2024.105321
Emiliano Bruner
{"title":"In search for evolutionary roots of a mindful cognition: A Darwinian view on sustained intentional awareness","authors":"Emiliano Bruner","doi":"10.1016/j.biosystems.2024.105321","DOIUrl":"10.1016/j.biosystems.2024.105321","url":null,"abstract":"<div><p>The attention system underwent important evolutionary changes and specializations in the human genus. In fact, our outstanding social and technological complexity strictly depends on our attentional ability, which is sustained, intentional, and conscious. Attention, intention, and awareness are key features for what can be defined a <em>mindful cognition</em>, and we may wonder whether a specific combination of these cognitive traits may be the result of a natural selective process, or else an accidental by-product of mental complexity. In this article, basic concepts in evolutionary anthropology are reviewed, to consider whether positive, neutral, or negative selective forces might have influenced the evolution of a mindful cognitive ability. At present, all these alternatives are potentially supported by different kinds of evidence. Hybrid hypotheses, considering stabilizing mechanisms or distinct social roles and intra-specific variation, are also likely. An evolutionary approach to the cognitive abilities involved in attention and awareness can reveal potentialities, limitations, and drawbacks of our individual and collective natural behaviors, especially when dealing with the evolution of the human consciousness.</p></div>","PeriodicalId":50730,"journal":{"name":"Biosystems","volume":"246 ","pages":"Article 105321"},"PeriodicalIF":2.0,"publicationDate":"2024-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0303264724002065/pdfft?md5=6142cf91f5ea36f97701fdc162244977&pid=1-s2.0-S0303264724002065-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142134337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The genetic code and its p-adic ultrametric modeling 遗传密码及其 p-adic 超参数模型。
IF 2 4区 生物学
Biosystems Pub Date : 2024-09-02 DOI: 10.1016/j.biosystems.2024.105322
Branko Dragovich , Nataša Ž. Mišić
{"title":"The genetic code and its p-adic ultrametric modeling","authors":"Branko Dragovich ,&nbsp;Nataša Ž. Mišić","doi":"10.1016/j.biosystems.2024.105322","DOIUrl":"10.1016/j.biosystems.2024.105322","url":null,"abstract":"<div><p>The genetic code plays a central role in all living organisms and its modeling is important for describing and understanding involved the coding rules. There are many approaches to modeling various aspects of the genetic code. One of the simple and successful mathematical tools for modeling the similarity both between codons and between amino acids, is the ultrametrics and especially the <span><math><mi>p</mi></math></span>-adic distance. This article contains an overview of ultrametric (<span><math><mi>p</mi></math></span>-adic) modeling of genetic information, and its translation to proteins using the genetic code.</p></div>","PeriodicalId":50730,"journal":{"name":"Biosystems","volume":"246 ","pages":"Article 105322"},"PeriodicalIF":2.0,"publicationDate":"2024-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142134338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
On the possibility of implementing a quantum entanglement distribution in a biosystem: Microtubules 在生物系统中实现量子纠缠分布的可能性:微管
IF 2 4区 生物学
Biosystems Pub Date : 2024-08-28 DOI: 10.1016/j.biosystems.2024.105320
Sergey E. Shirmovsky
{"title":"On the possibility of implementing a quantum entanglement distribution in a biosystem: Microtubules","authors":"Sergey E. Shirmovsky","doi":"10.1016/j.biosystems.2024.105320","DOIUrl":"10.1016/j.biosystems.2024.105320","url":null,"abstract":"<div><p>The paper considers the possibility of implementing a quantum entanglement distribution in the cell microtubule. It has been shown that a quantum entanglement distribution proposed in the paper determines the process of quantum state teleportation through microtubule tryptophan chain. The work shows that the system of tryptophans in a microtubule essentially is a quantum network that consists of: spatially spaced nodes — tryptophans, quantum communication channels connecting tryptophans and qubits transmitted through these communication channels. The connection between the process of quantum teleportation in living nature and its classical analogue is discussed. The quantum protocol established in the work determines the possible principle of quantum information transmission in biosystems and also in the similar nanostructures.</p></div>","PeriodicalId":50730,"journal":{"name":"Biosystems","volume":"245 ","pages":"Article 105320"},"PeriodicalIF":2.0,"publicationDate":"2024-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142094660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Advanced technologies and mathematical metacognition: The present and future orientation 先进技术与数学元认知:现在和未来的方向。
IF 2 4区 生物学
Biosystems Pub Date : 2024-08-26 DOI: 10.1016/j.biosystems.2024.105312
Alexios Kouzalis , Antonios Antoniou , Nicos Rossides , Rita Panaoura , Priyanka Yadav
{"title":"Advanced technologies and mathematical metacognition: The present and future orientation","authors":"Alexios Kouzalis ,&nbsp;Antonios Antoniou ,&nbsp;Nicos Rossides ,&nbsp;Rita Panaoura ,&nbsp;Priyanka Yadav","doi":"10.1016/j.biosystems.2024.105312","DOIUrl":"10.1016/j.biosystems.2024.105312","url":null,"abstract":"<div><p>The intersection of mathematical cognition, metacognition, and advanced technologies presents a frontier with profound implications for human learning and artificial intelligence. This paper traces the historical roots of these concepts from the Pythagoreans and Aristotle to modern cognitive science and explores their relevance to contemporary technological applications. We examine how the Pythagoreans' view of mathematics as fundamental to understanding the universe and Aristotle's contributions to logic and categorization have shaped our current understanding of mathematical cognition and metacognition. The paper investigates the role of Boolean logic in computational processes and its relationship to human logical reasoning, as well as the significance of Bayesian inference and fuzzy logic in modelling uncertainty in human cognition and decision-making. We also explore the emerging field of Chemical Artificial Intelligence and its potential applications. We argue for unifying mathematical metacognition with advanced technologies, including artificial intelligence and robotics, while identifying the multifaceted benefits and challenges of such unification. The present paper examines essential research directions for integrating cognitive sciences and advanced technologies, discussing applications in education, healthcare, and business management. We provide suggestions for developing cognitive robots using specific cognitive tasks and explore the ethical implications of these advancements. Our analysis underscores the need for interdisciplinary collaboration to realize the full potential of this integration while mitigating potential risks.</p></div>","PeriodicalId":50730,"journal":{"name":"Biosystems","volume":"245 ","pages":"Article 105312"},"PeriodicalIF":2.0,"publicationDate":"2024-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142057199","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Corrigendum to “An efficient approach for identifying important biomarkers for biomedical diagnosis” [Biosystems 237 (2024) 105163] 生物医学诊断中重要生物标志物的有效识别方法"[Biosystems 237 (2024) 105163]更正。
IF 2 4区 生物学
Biosystems Pub Date : 2024-08-21 DOI: 10.1016/j.biosystems.2024.105286
Jing-Wen Huang , Yan-Hong Chen , Frederick Kin Hing Phoa , Yan-Han Lin , Shau-Ping Lin
{"title":"Corrigendum to “An efficient approach for identifying important biomarkers for biomedical diagnosis” [Biosystems 237 (2024) 105163]","authors":"Jing-Wen Huang ,&nbsp;Yan-Hong Chen ,&nbsp;Frederick Kin Hing Phoa ,&nbsp;Yan-Han Lin ,&nbsp;Shau-Ping Lin","doi":"10.1016/j.biosystems.2024.105286","DOIUrl":"10.1016/j.biosystems.2024.105286","url":null,"abstract":"","PeriodicalId":50730,"journal":{"name":"Biosystems","volume":"244 ","pages":"Article 105286"},"PeriodicalIF":2.0,"publicationDate":"2024-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0303264724001710/pdfft?md5=99936dead43c78edec8d85e4c0f80013&pid=1-s2.0-S0303264724001710-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142019472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Why does a cell function? New arguments in favor of quantum effects 细胞为何能发挥作用?支持量子效应的新论点
IF 2 4区 生物学
Biosystems Pub Date : 2024-08-20 DOI: 10.1016/j.biosystems.2024.105311
A.V. Melkikh
{"title":"Why does a cell function? New arguments in favor of quantum effects","authors":"A.V. Melkikh","doi":"10.1016/j.biosystems.2024.105311","DOIUrl":"10.1016/j.biosystems.2024.105311","url":null,"abstract":"<div><p>In this study, the complexities of intracellular processes have been analyzed, including DNA folding, alternative splicing, mitochondrial function, and enzyme transport in lysosomes. Based on a previously proposed hypothesis (Levinthal's generalized paradox), a conclusion is made that all abovementioned processes cannot be realized with sufficient accuracy and in a realistic timeframe within the framework of classical physics. It is unclear why the cell functions at all. For the cell to function, its internal environment must be highly structured. In this regard, the cell shares similarities with computational devices (computers). In this study, quantum models of interactions between biologically important molecules were constructed, taking into account the long-range effects. One significant aspect of these models is the special role of the phase of the wavefunction, which serves as a controlling parameter. Experiments have been proposed that may confirm or refute these models.</p></div>","PeriodicalId":50730,"journal":{"name":"Biosystems","volume":"245 ","pages":"Article 105311"},"PeriodicalIF":2.0,"publicationDate":"2024-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142037641","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparing the complexity of written and molecular symbolic systems 比较书面和分子符号系统的复杂性。
IF 2 4区 生物学
Biosystems Pub Date : 2024-08-20 DOI: 10.1016/j.biosystems.2024.105297
Julia Esposito , Jyotika Kakar , Tasneem Khokhar , Tiana Noll-Walker , Fatima Omar , Anna Christen , H. James Cleaves II , McCullen Sandora
{"title":"Comparing the complexity of written and molecular symbolic systems","authors":"Julia Esposito ,&nbsp;Jyotika Kakar ,&nbsp;Tasneem Khokhar ,&nbsp;Tiana Noll-Walker ,&nbsp;Fatima Omar ,&nbsp;Anna Christen ,&nbsp;H. James Cleaves II ,&nbsp;McCullen Sandora","doi":"10.1016/j.biosystems.2024.105297","DOIUrl":"10.1016/j.biosystems.2024.105297","url":null,"abstract":"<div><p>Symbolic systems (SSs) are uniquely products of living systems, such that symbolism and life may be inextricably intertwined phenomena. Within a given SS, there is a range of symbol complexity over which signaling is functionally optimized. This range exists relative to a complex and potentially infinitely large background of latent, unused symbol space. Understanding how symbol sets sample this latent space is relevant to diverse fields including biochemistry and linguistics.</p><p>We quantitatively explored the graphic complexity of two biosemiotic systems: genetically encoded amino acids (GEAAs) and written language. Molecular and graphical notions of complexity are highly correlated for GEAAs and written language. Symbol sets are generally neither minimally nor maximally complex relative to their latent spaces, but exist across an objectively definable distribution, with the GEAAs having especially low complexity. The selection pressures guiding these disparate systems are explicable by symbol production and disambiguation efficiency. These selection pressures may be universal, offer a quantifiable metric for comparison, and suggest that all life in the Universe may discover optimal symbol set complexity distributions with respect to their latent spaces. If so, the “complexity” of individual components of SSs may not be as strong a biomarker as symbol set complexity distribution.</p></div>","PeriodicalId":50730,"journal":{"name":"Biosystems","volume":"244 ","pages":"Article 105297"},"PeriodicalIF":2.0,"publicationDate":"2024-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142001261","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Developmental noise, entropy, and biological system condition 发育噪音、熵和生物系统状况
IF 2 4区 生物学
Biosystems Pub Date : 2024-08-18 DOI: 10.1016/j.biosystems.2024.105310
Vladimir M. Zakharov, Ilya E. Trofimov
{"title":"Developmental noise, entropy, and biological system condition","authors":"Vladimir M. Zakharov,&nbsp;Ilya E. Trofimov","doi":"10.1016/j.biosystems.2024.105310","DOIUrl":"10.1016/j.biosystems.2024.105310","url":null,"abstract":"<div><p>Developmental noise is considered as a permissible level of entropy, as a compromise between the cost and needed precision of the realization of genetic information. In terms of entropy, noise is a measure of acceptable level of disorder to ensure a reliable system operation. Developmental noise plays a role in the observed phenotypic diversity and is associated with other indicators of the biological system condition. The thermodynamic characteristic of entropy by the energy metabolism also turns out to be related to the developmental noise. Phenotypic variability is largely determined by developmental homeostasis, including both canalization (an ability to form a similar phenotype under different conditions) and developmental stability (a capability for perfect development measured by noise level). It is shown that the change in the noise level, as an expression of the certain entropy level, unlike other forms of phenotypic variability, is a reflection of a change in the system condition. Although the entropy indices of ontogeny and community under certain conditions can change simultaneously, the entropy index at the level of developmental noise proves to be a more unambiguous and universal measure of the disorder of a biological system, compared to biodiversity indices at the community level.</p></div>","PeriodicalId":50730,"journal":{"name":"Biosystems","volume":"244 ","pages":"Article 105310"},"PeriodicalIF":2.0,"publicationDate":"2024-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142001262","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Micro-electrode array recording of extracellular electrical potentials of liquid static surface fermented Hericium erinaceus 微电极阵列记录液体静态表面发酵草本植物的细胞外电位
IF 2 4区 生物学
Biosystems Pub Date : 2024-08-17 DOI: 10.1016/j.biosystems.2024.105298
Davin Browner, Andrew Adamatzky
{"title":"Micro-electrode array recording of extracellular electrical potentials of liquid static surface fermented Hericium erinaceus","authors":"Davin Browner,&nbsp;Andrew Adamatzky","doi":"10.1016/j.biosystems.2024.105298","DOIUrl":"10.1016/j.biosystems.2024.105298","url":null,"abstract":"<div><p><em>Hericium erinaceus</em> is a basidiomycetes fungus with previously uncharacterised extracellular electrophysiology. Here, we present results of recordings of the electrical potentials of fungal biofilms of this species using microelectrode arrays (MEAs). In particular, we focused on modelling the temporal and spatial progression of the low frequency (<span><math><mo>≤</mo></math></span> 1 Hz) potentials. Culture media control studies showed that the electrical potential activity results from the growth and subsequent spiking behaviours of the mycelium extracellular matrices. An antifungal assay using nystatin suspension, 10,000 unit/mL in DPBS, provided evidence for the biological origin of electrical potentials due to targeting of the selective permeability of the cell membrane and subsequent cessation of electrical activity. Conversely, injection of L-glutamic acid increased the combined multi-channel mean firing rate from 0.04 Hz to 0.1 Hz. Analysis of bursting and spatial propagation of the extracellular signals are also presented.</p></div>","PeriodicalId":50730,"journal":{"name":"Biosystems","volume":"245 ","pages":"Article 105298"},"PeriodicalIF":2.0,"publicationDate":"2024-08-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0303264724001837/pdfft?md5=2dbd9b09c85e85104e02db231527f890&pid=1-s2.0-S0303264724001837-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142005742","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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