{"title":"Placental biomarkers in the first trimester and adverse pregnancy outcome.","authors":"Maryam Amjad","doi":"10.1111/1471-0528.17868","DOIUrl":"10.1111/1471-0528.17868","url":null,"abstract":"","PeriodicalId":50729,"journal":{"name":"Bjog-An International Journal of Obstetrics and Gynaecology","volume":" ","pages":"1516"},"PeriodicalIF":4.3,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141302077","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Fred Tweneboah-Koduah, Nana Mintah-Afful, Isaac Lartey Narh, Kwasi Eba-Polley, Catherine Narh Menka, Prince Osei, Nana Osei, Lemuel Lartey, Bernard Bortieh, Cletus Kumi, Elijah Boafo, Janet Ayorkor Anyetei, Edel Issabella Arthur, Horatio King Glover, Fredrick Amoah, Ethel Larteley Boye, Zerish Lamptey, Laurinda Gyan, Jie Sun, Julie Taylor, Paula Briggs, Lucky Saraswat, Sharron Hinchliff, Kristina Potocnik, Kathryn Elliot, Nick Panay, Carol Atkinson, Vikram Talaulikar, George Uchenna Eleje, Om Kurmi, Nirmala Rathnayake, Tharanga Mudalige, Vindya Pathiraja, Jeevan Dhanarisi, Lamiya Al-Kharusi, Nihal Al-Riyami, Bernard Mbwele, Ieera Madan-Aggarwal, Toh Teck Hock, David Chibuike Ikwuka, Pradip K Mitra, Muhammad Irfan, Rabia Kareem, Crisitina Benetti-Pinto, Helen Felecity Kemp, Ramiya Palanisamy, Jian Shi, Sohier Elneil, Peter Phiri, Gayathri Delanerolle
{"title":"Menopause as an Embodied and Occupational Disruption: A Qualitative Study of Women's Experiences in Ghana (MARIE-WP2a).","authors":"Fred Tweneboah-Koduah, Nana Mintah-Afful, Isaac Lartey Narh, Kwasi Eba-Polley, Catherine Narh Menka, Prince Osei, Nana Osei, Lemuel Lartey, Bernard Bortieh, Cletus Kumi, Elijah Boafo, Janet Ayorkor Anyetei, Edel Issabella Arthur, Horatio King Glover, Fredrick Amoah, Ethel Larteley Boye, Zerish Lamptey, Laurinda Gyan, Jie Sun, Julie Taylor, Paula Briggs, Lucky Saraswat, Sharron Hinchliff, Kristina Potocnik, Kathryn Elliot, Nick Panay, Carol Atkinson, Vikram Talaulikar, George Uchenna Eleje, Om Kurmi, Nirmala Rathnayake, Tharanga Mudalige, Vindya Pathiraja, Jeevan Dhanarisi, Lamiya Al-Kharusi, Nihal Al-Riyami, Bernard Mbwele, Ieera Madan-Aggarwal, Toh Teck Hock, David Chibuike Ikwuka, Pradip K Mitra, Muhammad Irfan, Rabia Kareem, Crisitina Benetti-Pinto, Helen Felecity Kemp, Ramiya Palanisamy, Jian Shi, Sohier Elneil, Peter Phiri, Gayathri Delanerolle","doi":"10.1111/1471-0528.70189","DOIUrl":"10.1111/1471-0528.70189","url":null,"abstract":"<p><strong>Objective: </strong>To explore the lived experiences of perimenopause/menopause among Ghanaian women.</p><p><strong>Design: </strong>Qualitative study using in-depth, semi-structured interviews.</p><p><strong>Setting: </strong>Community and hospital based settings across Ghana, where women's lives are largely shaped by informal trade, caregiving, and gendered work roles.</p><p><strong>Population: </strong>Perimenopausal, menopausal, and post-menopausal women aged between 18 and 99 years that provided informed consent.</p><p><strong>Methods: </strong>A qualitative methodology was used based on a topics guide that was developed following an evidence synthesis, patient-public involvement and expert opinions. Interviews explored experiences linked to symptoms, healthcare access, coping strategies, work-life balance, and societal perceptions. Data were analysed using Braun and Clarke's six-phase reflexive thematic analysis to identify key patterns and meanings.</p><p><strong>Main outcome measures: </strong>Experiences and perceptions of menopause, including symptom burden, coping mechanisms, and barriers to care.</p><p><strong>Results: </strong>Six interconnected themes were identified. Menopause intensified occupational and economic strain, with symptoms disrupting income generation and caregiving. Psychological burden and emotional disruption were widespread, often concealed due to stigma. Physical and somatic symptoms significantly impaired daily functioning. Barriers to healthcare included limited awareness, fragmented services, and low prioritisation of menopause. Women adopted coping and resilience strategies, such as herbal remedies and social withdrawal. Outlook, migration, and intergenerational lessons shaped planning for future generations.</p><p><strong>Conclusions: </strong>Menopause in Ghana is a neglected occupational and sociocultural health issue. Integrating menopause care into chronic disease and mental health services, improving access, and enhancing workplace protections are critical.</p>","PeriodicalId":50729,"journal":{"name":"Bjog-An International Journal of Obstetrics and Gynaecology","volume":" ","pages":"1453-1464"},"PeriodicalIF":4.3,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147277465","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Bernd Froessler, Michaela Malek, Mathonsi Jila, Anupam Parange, Thu-Lan Kelly
{"title":"The carbon footprint of nitrous oxide use for birth.","authors":"Bernd Froessler, Michaela Malek, Mathonsi Jila, Anupam Parange, Thu-Lan Kelly","doi":"10.1111/1471-0528.17873","DOIUrl":"10.1111/1471-0528.17873","url":null,"abstract":"","PeriodicalId":50729,"journal":{"name":"Bjog-An International Journal of Obstetrics and Gynaecology","volume":" ","pages":"1517-1518"},"PeriodicalIF":4.3,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141161395","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Spontaneous haemoperitoneum: Arterial versus venous haemorrhage.","authors":"Shunji Suzuki","doi":"10.1111/1471-0528.17874","DOIUrl":"10.1111/1471-0528.17874","url":null,"abstract":"","PeriodicalId":50729,"journal":{"name":"Bjog-An International Journal of Obstetrics and Gynaecology","volume":" ","pages":"1519"},"PeriodicalIF":4.3,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141155073","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"SOX1/PAX1 Methylation for Triage of HPV-Positive Women in Cervical Cancer Screening: A Cohort Study.","authors":"Hongyu Xie, Junyan Li, Huiru Huang, Ansong Emmanuel, Hui Wang, Weiguo Lu, Xiao Li","doi":"10.1111/1471-0528.70162","DOIUrl":"10.1111/1471-0528.70162","url":null,"abstract":"<p><strong>Objective: </strong>To establish a better triage strategy using SOX1/PAX1 methylation detection for high-risk HPV (hrHPV)-positive women than cytology.</p><p><strong>Design: </strong>A cohort study.</p><p><strong>Setting: </strong>Population-based cervical cancer (CC) screening cohort.</p><p><strong>Population: </strong>A total of 5684 women were enrolled.</p><p><strong>Methods: </strong>SOX1/PAX1 methylation was detected by quantitative methylation-specific PCR using cytologic residue from hrHPV-positive women at baseline in a 3-year CC screening cohort. Risk stratification ability was evaluated by the immediate and cumulative cervical intraepithelial neoplasia (CIN) grade 2/3 or worse (CIN2+/3+) risks.</p><p><strong>Main outcome measures: </strong>CIN3+ and CIN2+.</p><p><strong>Results: </strong>At baseline, 682 hrHPV-positive women were included with 63 CIN2+ and 39 CIN3+. Over 3 years, 109 CIN2+ and 62 CIN3+ were detected. Methylation demonstrated better risk stratification than cytology among hrHPV-positive women. When compared with current practice triage strategy (Strategy A), post hoc re-triage analysis showed that methylation triage for all hrHPV-positive women (Strategy C) significantly increased sensitivity (97.44%/83.87% vs. 84.62%/64.52%, p = 0.0476/0.014), specificity (83.36%/85.00% vs. 73.41%/73.55%, p = < 0.001/< 0.001), positive predictive value (26.21%/35.86% vs. 16.18%/19.61%, p = 0.022/0.001), and negative predictive value (99.81%/98.14% vs. 98.74%/95.40%, p = 0.040/0.012) in detecting immediate and 3-year cumulative CIN3+. Similar improvements were observed for methylation triaged for HR12-positive (Strategy B) and for combined HPV and cytology primary screening (Strategy D). More importantly, all methylation-based triage strategies reduced colposcopies and postponed follow-up intervals compared to Strategy A over the 3-year period of CC screening.</p><p><strong>Conclusion: </strong>SOX1/PAX1 methylation showed better risk stratification compared with cytology and enabled more efficient management of HPV-positive women, though external validation and head-to-head comparisons with other triage methods are needed.</p>","PeriodicalId":50729,"journal":{"name":"Bjog-An International Journal of Obstetrics and Gynaecology","volume":" ","pages":"1431-1440"},"PeriodicalIF":4.3,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13143549/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146004624","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Author Reply.","authors":"Dag Moster, Allen J Wilcox, Rolv Terje Lie","doi":"10.1111/1471-0528.70155","DOIUrl":"10.1111/1471-0528.70155","url":null,"abstract":"","PeriodicalId":50729,"journal":{"name":"Bjog-An International Journal of Obstetrics and Gynaecology","volume":" ","pages":"1511"},"PeriodicalIF":4.3,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145967740","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ana Nelia Jumamil, Joemer Calderon Maravilla, Joycelyn Abiog Filoteo, Charlene Joy Mendoza Sta Maria, Angelica Villanueva Felipe, Rachelle Sarmiento, Anna Liza Alfonso, Mayla Rivera, Jose Edwardo Mamaat, Arbie Diane Flores, Mary Ann Bayani, Reinalyn Lim Cardenas, Wilfredo Quijencio, Nemencio Santos, Joyce Lisa Acena, Rebecca A Guariño, Ida Stevia Diget, Alma Trinidad Taragua, Frances M Boyle
{"title":"Bereavement Care Experiences of Mothers Following Stillbirth and Neonatal Death: A Latent Class Analysis.","authors":"Ana Nelia Jumamil, Joemer Calderon Maravilla, Joycelyn Abiog Filoteo, Charlene Joy Mendoza Sta Maria, Angelica Villanueva Felipe, Rachelle Sarmiento, Anna Liza Alfonso, Mayla Rivera, Jose Edwardo Mamaat, Arbie Diane Flores, Mary Ann Bayani, Reinalyn Lim Cardenas, Wilfredo Quijencio, Nemencio Santos, Joyce Lisa Acena, Rebecca A Guariño, Ida Stevia Diget, Alma Trinidad Taragua, Frances M Boyle","doi":"10.1111/1471-0528.70190","DOIUrl":"10.1111/1471-0528.70190","url":null,"abstract":"<p><strong>Objective: </strong>This study examined nuanced preferences and unmet needs for bereavement care of mothers who experienced stillbirth or neonatal death.</p><p><strong>Design: </strong>Cross-sectional survey.</p><p><strong>Setting: </strong>The Philippines.</p><p><strong>Sample: </strong>A total of 169 bereaved mothers aged 18 years or older who had experienced stillbirth or neonatal death on or after 30 January 2020 in the Philippines.</p><p><strong>Methods: </strong>Response patterns to nine self-administered questions about desired bereavement care and the care they received were analysed using latent class analysis. Measurement invariance was assessed across participant types and urbanicity. Multinomial logistic regression was used to examine the associations between latent classes, demographics and perinatal loss information.</p><p><strong>Main outcome measures: </strong>Desired type of bereavement care and unmet need for bereavement care.</p><p><strong>Results: </strong>We identified three mutually exclusive stable latent classes related to desired care and unmet needs. For desired bereavement care, one class was characterised by a strong preference for seeing, holding, spending time with, and naming the baby, but low desire in memory making (25.1%). This preference was more common among mothers from urban areas (aOR = 3.04) and those who experienced stillbirth (aOR = 3.07), compared to those from rural areas and who experienced neonatal death, respectively. Regarding unmet need for bereavement care, one class reported unmet needs for memory making (28.3%), with preterm mothers (aOR = 3.11) three times more likely to belong to this class than those who delivered full-term.</p><p><strong>Conclusion: </strong>This study offers novel insights into the complex bereavement care preferences and needs of mothers who experienced perinatal loss. The findings can inform future frameworks and guide the development of culturally appropriate, context-specific interventions for mothers and families.</p>","PeriodicalId":50729,"journal":{"name":"Bjog-An International Journal of Obstetrics and Gynaecology","volume":" ","pages":"1465-1474"},"PeriodicalIF":4.3,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13143561/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147285992","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jhia Jiat Teh, Filipa Campos, Adam Koczoski, Trisha Valencia, Michael P Rimmer, Bassel H Al Wattar
{"title":"Effectiveness of Virtual Reality for Pain Relief in Procedures Related to Obstetrics and Gynaecology: A Systematic Review and Meta-Analysis of Randomised Controlled Trials.","authors":"Jhia Jiat Teh, Filipa Campos, Adam Koczoski, Trisha Valencia, Michael P Rimmer, Bassel H Al Wattar","doi":"10.1111/1471-0528.70194","DOIUrl":"10.1111/1471-0528.70194","url":null,"abstract":"<p><strong>Background: </strong>Immersive virtual reality (VR) technology offers a non-invasive, non-pharmacological approach to reduce pain perception in patients undergoing diagnostic or interventional procedures.</p><p><strong>Objective: </strong>To systematically evaluate the efficacy of immersive VR technology in reducing pain perception during obstetric and gynaecological procedures.</p><p><strong>Search strategy: </strong>We searched MEDLINE, EMBASE, CENTRAL, and CINAHL databases from inception to January 2025.</p><p><strong>Selection criteria: </strong>We included randomised controlled trials (RCTs) evaluating VR interventions in women undergoing obstetric or gynaecological procedures.</p><p><strong>Data collection and analysis: </strong>We performed meta-analyses using random-effects models and assessed risk of bias using the Cochrane risk-of-bias tool for randomised trials.</p><p><strong>Main results: </strong>49 RCTs (5355 participants) were included. Due to clinical heterogeneity, data were analysed separately. VR resulted in a larger, consistent reduction in pain scores compared with standard care in labour (11 studies; SMD -0.93, 95% CI -1.25 to -0.60) compared to minor procedures (29 studies; SMD -0.64, 95% CI -0.97 to -0.32). VR also significantly reduced anxiety scores in both labour (8 studies; SMD -1.13, 95% CI -1.80 to -0.45) and minor procedures (17 studies; SMD -0.74, 95% CI -1.18 to -0.29). Our analysis was limited by high levels of heterogeneity and variability in procedural protocols.</p><p><strong>Conclusion: </strong>Immersive VR technology appears effective for reducing pain and anxiety during obstetric and gynaecological procedures, particularly during childbirth, despite substantial statistical heterogeneity. Further research is needed to optimise implementation strategies and establish clinical practice guidelines.</p>","PeriodicalId":50729,"journal":{"name":"Bjog-An International Journal of Obstetrics and Gynaecology","volume":" ","pages":"1358-1372"},"PeriodicalIF":4.3,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13143552/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147285917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Antoniya Georgieva, Mariana Tomé, Aimée A K Lovers, Lawrence W Impey, Jane Elizabeth Hirst
{"title":"Author Reply.","authors":"Antoniya Georgieva, Mariana Tomé, Aimée A K Lovers, Lawrence W Impey, Jane Elizabeth Hirst","doi":"10.1111/1471-0528.70157","DOIUrl":"10.1111/1471-0528.70157","url":null,"abstract":"","PeriodicalId":50729,"journal":{"name":"Bjog-An International Journal of Obstetrics and Gynaecology","volume":" ","pages":"1514-1515"},"PeriodicalIF":4.3,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145967720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Correction to 'Management of Thyroid Disorders in Pregnancy'.","authors":"","doi":"10.1111/1471-0528.70259","DOIUrl":"https://doi.org/10.1111/1471-0528.70259","url":null,"abstract":"","PeriodicalId":50729,"journal":{"name":"Bjog-An International Journal of Obstetrics and Gynaecology","volume":" ","pages":""},"PeriodicalIF":4.3,"publicationDate":"2026-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147845629","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}