Prathiba M De Silva, Paul P Smith, Natalie A M Cooper, T Justin Clark
{"title":"Outpatient Hysteroscopy: (Green-top Guideline no. 59).","authors":"Prathiba M De Silva, Paul P Smith, Natalie A M Cooper, T Justin Clark","doi":"10.1111/1471-0528.17907","DOIUrl":"https://doi.org/10.1111/1471-0528.17907","url":null,"abstract":"<p><p>All gynaecology departments should provide a dedicated outpatient hysteroscopy service to aid care of women and people with abnormal uterine bleeding, reproductive problems, and insertion/retrieval of intrauterine devices. [Grade A] Written information should be provided to the woman prior to their appointment. This should include details about the procedure, the benefits and risks, advice regarding pre-operative analgesia, as well as alternative options for care and contact details for the hysteroscopy unit. [Good Practice Point] Women should be made aware of other settings and modes of anaesthesia for hysteroscopy (e.g. under general or regional anaesthesia or intravenous sedation). [GPP] The woman should be advised that if they find the procedure too painful or distressing at any point, they must alert the clinical team who will stop the procedure immediately. The clinical team should alert the hysteroscopist if the woman appears to be in too much pain or is experiencing a vasovagal episode and therefore unable to voice the concerns so that the procedure can be stopped. [GPP] Women should be advised to take standard doses of oral non-steroidal anti-inflammatory agents (NSAIDs) one hour before their scheduled appointment. Vaginoscopy should be the standard technique for outpatient hysteroscopy unless the use of a vaginal speculum is required (e.g. for administering local cervical anaesthesia or dilating the cervix). [Grade A] When performing operative hysteroscopy, the smallest diameter hysteroscope should be used, with consideration given to the use of hysteroscopes with expandable outer working channels because they are associated with less pain. [Grade B] Mechanical hysteroscopic tissue removal systems should be preferred over miniature bipolar electrodes to remove endometrial polyps. [Grade A] Local anaesthesia should not be routinely administered prior to outpatient hysteroscopy where a vaginoscopic approach is used. It should be considered where use of a vaginal speculum is planned e.g. for cervical dilatation if anticipated, due to either cervical stenosis and/or the utilisation of larger-diameter hysteroscopes (≥5mm outer diameter). [Grade A] Saline should be instilled at the lowest possible pressure to achieve a satisfactory view. [Grade A] Conscious sedation should not be routinely used in outpatient hysteroscopic procedures. [Grade B].</p>","PeriodicalId":50729,"journal":{"name":"Bjog-An International Journal of Obstetrics and Gynaecology","volume":null,"pages":null},"PeriodicalIF":4.7,"publicationDate":"2024-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142005740","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Eric Jauniaux, Christoph Lees, Amar Bhide, Elizabeth Daly-Jones, Deepa Srinivasan, Yinka Oyelese
{"title":"The placenta and umbilical cord in prenatal care: Unseen, overlooked and misunderstood.","authors":"Eric Jauniaux, Christoph Lees, Amar Bhide, Elizabeth Daly-Jones, Deepa Srinivasan, Yinka Oyelese","doi":"10.1111/1471-0528.17936","DOIUrl":"https://doi.org/10.1111/1471-0528.17936","url":null,"abstract":"","PeriodicalId":50729,"journal":{"name":"Bjog-An International Journal of Obstetrics and Gynaecology","volume":null,"pages":null},"PeriodicalIF":4.7,"publicationDate":"2024-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141983816","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sarah Saleem, Haleema Yasmin, Janet L Moore, Anum Rahim, Iram Shakeel, Adrien Lokangaka, Antoinette Tshefu, Melissa Bauserman, Musaku Mwenechanya, Elwyn Chomba, Shivaprasad S Goudar, Avinash Kavi, Richard J Derman, Nancy F Krebs, Lester Figueroa, Manolo Mazariegos, Paul Nyongesa, Sherri Bucher, Fabian Esamai, Archana Patel, Manjushree Waikar, Poonam Shivkumar, Patricia L Hibberd, William A Petri, Sk Masum Billah, Rashidul Haque, Waldemar A Carlo, Alan Tita, Marion Koso-Thomas, Jennifer Hemingway-Foday, Elizabeth M McClure, Robert L Goldenberg
{"title":"Intrapartum and postpartum antibiotic use in seven low- and middle-income countries: Findings from the A-PLUS trial.","authors":"Sarah Saleem, Haleema Yasmin, Janet L Moore, Anum Rahim, Iram Shakeel, Adrien Lokangaka, Antoinette Tshefu, Melissa Bauserman, Musaku Mwenechanya, Elwyn Chomba, Shivaprasad S Goudar, Avinash Kavi, Richard J Derman, Nancy F Krebs, Lester Figueroa, Manolo Mazariegos, Paul Nyongesa, Sherri Bucher, Fabian Esamai, Archana Patel, Manjushree Waikar, Poonam Shivkumar, Patricia L Hibberd, William A Petri, Sk Masum Billah, Rashidul Haque, Waldemar A Carlo, Alan Tita, Marion Koso-Thomas, Jennifer Hemingway-Foday, Elizabeth M McClure, Robert L Goldenberg","doi":"10.1111/1471-0528.17930","DOIUrl":"https://doi.org/10.1111/1471-0528.17930","url":null,"abstract":"<p><strong>Objective: </strong>To describe the intrapartum and postpartum use of non-study antibiotics in low- and middle-income countries (LMICs) during the double-blinded NICHD Global Network Azithromycin in Labor (A-PLUS) trial.</p><p><strong>Design: </strong>The antibiotic use sub-study was a planned prospective, observational sub-study of the A-PLUS trial.</p><p><strong>Settings: </strong>The study was carried out in hospitals or health centres affiliated with eight sites of the Global Network for Women's and Children's Health Research (Global Network) in seven countries: Bangladesh, Pakistan, India (two sites), Kenya, Zambia, The Democratic Republic of the Congo (DRC) and Guatemala.</p><p><strong>Population: </strong>Totally, 29 278 pregnant women enrolled in the A-PLUS trial.</p><p><strong>Methods: </strong>We collected data on 29 278 pregnant women admitted to a facility for delivery related to non-study antibiotic use overall and during three time periods: (1) in the facility prior to delivery, (2) after delivery until facility discharge and (3) after discharge to 42 days post-partum.</p><p><strong>Main outcome measures: </strong>Non-study antibiotic use overall and for treatment or prophylaxis by the site during the three time periods.</p><p><strong>Results: </strong>Of the 29 278 women in the study, 5020 (17.1%; 95% CI 16.7%-17.6%) received non-study antibiotics in the facility prior to delivery, 11 956 (40.8%; 95% CI 40.3%-41.4%) received non-study antibiotics in the facility after delivery, and 13 390 (47.6%; 95% CI 47.0%-48.2%) women received non-study antibiotics after delivery and after facility discharge. Antibiotics were prescribed more often among women in the Asian and Guatemalan sites than in the African sites. In the three time-periods, among those receiving antibiotics, prophylaxis was the indication in 82.3%, 97.7% and 90.7% of the cases, respectively. The type of antibiotics used varied substantially by time-period and site, but generally, penicillin-type drugs, cephalosporin-type drugs and metronidazole were used more frequently than other types.</p><p><strong>Conclusions: </strong>Across the eight sites of the Global Network, in the facility before delivery, and in the post-partum periods before and after facility discharge, antibiotics were used frequently, but use was highly variable by site and time-period.</p>","PeriodicalId":50729,"journal":{"name":"Bjog-An International Journal of Obstetrics and Gynaecology","volume":null,"pages":null},"PeriodicalIF":4.7,"publicationDate":"2024-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141977123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Gabriel Levin, Walter Gotlieb, Pedro Ramirez, Raanan Meyer, Yoav Brezinov
{"title":"ChatGPT in a gynaecologic oncology multidisciplinary team tumour board: A feasibility study.","authors":"Gabriel Levin, Walter Gotlieb, Pedro Ramirez, Raanan Meyer, Yoav Brezinov","doi":"10.1111/1471-0528.17929","DOIUrl":"https://doi.org/10.1111/1471-0528.17929","url":null,"abstract":"","PeriodicalId":50729,"journal":{"name":"Bjog-An International Journal of Obstetrics and Gynaecology","volume":null,"pages":null},"PeriodicalIF":4.7,"publicationDate":"2024-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141977122","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Enhancing HPV vaccination and education to reduce vaginal cancer incidence.","authors":"Tomoyuki Kawada","doi":"10.1111/1471-0528.17935","DOIUrl":"https://doi.org/10.1111/1471-0528.17935","url":null,"abstract":"","PeriodicalId":50729,"journal":{"name":"Bjog-An International Journal of Obstetrics and Gynaecology","volume":null,"pages":null},"PeriodicalIF":4.7,"publicationDate":"2024-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141917984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Obstetric anal sphincter injuries during instrumental vaginal delivery.","authors":"Prathamesh Lanjewar, Avir Sarkar","doi":"10.1111/1471-0528.17931","DOIUrl":"https://doi.org/10.1111/1471-0528.17931","url":null,"abstract":"","PeriodicalId":50729,"journal":{"name":"Bjog-An International Journal of Obstetrics and Gynaecology","volume":null,"pages":null},"PeriodicalIF":4.7,"publicationDate":"2024-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141972283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Evaluating waterbirth risks: A deep dive into the POOL cohort study's research gaps.","authors":"Wei-Zhen Tang, Tai-Hang Liu, Xia Lan","doi":"10.1111/1471-0528.17934","DOIUrl":"https://doi.org/10.1111/1471-0528.17934","url":null,"abstract":"","PeriodicalId":50729,"journal":{"name":"Bjog-An International Journal of Obstetrics and Gynaecology","volume":null,"pages":null},"PeriodicalIF":4.7,"publicationDate":"2024-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141917985","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nina Cooper, Maya Al-Memar, Kristofer Linton-Reid, Keith Edmonds, Gillian Rose, Nuala Dixon, Cillian McNamara, Christina Fotopoulou, Katherine Van Ree, Nishat Bharwani
{"title":"Magnetic resonance imaging and clinical features of Mayer-Rokitansky-Küster-Hauser syndrome: A 10-year review from a dedicated specialist centre.","authors":"Nina Cooper, Maya Al-Memar, Kristofer Linton-Reid, Keith Edmonds, Gillian Rose, Nuala Dixon, Cillian McNamara, Christina Fotopoulou, Katherine Van Ree, Nishat Bharwani","doi":"10.1111/1471-0528.17928","DOIUrl":"https://doi.org/10.1111/1471-0528.17928","url":null,"abstract":"<p><strong>Objective: </strong>To correlate the clinical history with imaging findings of women with Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome.</p><p><strong>Design: </strong>Retrospective cohort study.</p><p><strong>Setting: </strong>A UK IOTA and ESGO-certified tertiary referral centre for disorders of reproductive development.</p><p><strong>Population: </strong>All patients with a diagnosis of MRKH and who had undergone an MRI pelvis between 1 January 2011 and 31 April 2021 were included.</p><p><strong>Methods: </strong>MRI images were analysed by specialist gynaecological radiologists. Clinical data was extracted from an electronic patient record system. Statistical analysis was computed in R (version 4.1.2), R base stats package and ggstatsplot (v0.5.0).</p><p><strong>Main outcome measures: </strong>Clinical history and predefined imaging features.</p><p><strong>Results: </strong>One hundred and thirty-four patients were included. Median age at MRI was 18 years (10-64 years). Half (48.2%) of women presenting had a history of pain, most often abdominal (84.6%) or vaginal (9.2%). Remnants were identified in 91.8% of women (n = 123). 4.5% of women had imaging features of endometriosis (n = 6). Women with a functional remnants were significantly more likely to experience pain (p < 0.001). Pain history was not strongly associated with ectopic ovarian position. Common gynaecological pathology such as endometriosis, ovarian cysts and fibroids were also identified.</p><p><strong>Conclusions: </strong>We identify that majority of women with MRKH will have uterine remnants with a connecting fibrous band, and an ectopic ovarian position 44.0% of cases. Abdominal pain was significantly associated with functional remnants on MRI. Further work is required to identify how other gynaecological pathology impacts women with MRKH.</p>","PeriodicalId":50729,"journal":{"name":"Bjog-An International Journal of Obstetrics and Gynaecology","volume":null,"pages":null},"PeriodicalIF":4.7,"publicationDate":"2024-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141917986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The impact of hormone therapy on cardiovascular risk in postmenopausal women: Insights and recommendations.","authors":"Luyang Su, Zeqing Du, Cuiqiao Meng","doi":"10.1111/1471-0528.17932","DOIUrl":"https://doi.org/10.1111/1471-0528.17932","url":null,"abstract":"","PeriodicalId":50729,"journal":{"name":"Bjog-An International Journal of Obstetrics and Gynaecology","volume":null,"pages":null},"PeriodicalIF":4.7,"publicationDate":"2024-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141908244","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alice Self, Michael Schlussel, Gary S Collins, Ferdinand Dhombres, Nicolas Fries, Georges Haddad, Laurent J Salomon, Mona Massoud, Aris T Papageorghiou
{"title":"External validation of models to estimate gestational age in the second and third trimester using ultrasound: A prospective multicentre observational study.","authors":"Alice Self, Michael Schlussel, Gary S Collins, Ferdinand Dhombres, Nicolas Fries, Georges Haddad, Laurent J Salomon, Mona Massoud, Aris T Papageorghiou","doi":"10.1111/1471-0528.17922","DOIUrl":"https://doi.org/10.1111/1471-0528.17922","url":null,"abstract":"<p><strong>Objectives: </strong>Accurate assessment of gestational age (GA) is important at both individual and population levels. The most accurate way to estimate GA in women who book late in pregnancy is unknown. The aim of this study was to externally validate the accuracy of equations for GA estimation in late pregnancy and to identify the best equation for estimating GA in women who do not receive an ultrasound scan until the second or third trimester.</p><p><strong>Design: </strong>This was a prospective, observational cross-sectional study.</p><p><strong>Setting: </strong>57 prenatal care centres, France.</p><p><strong>Participants: </strong>Women with a singleton pregnancy and a previous 11-14-week dating scan that gave the observed GA were recruited over an 8-week period. They underwent a standardised ultrasound examination at one time point during the pregnancy (15-43 weeks), measuring 12 foetal biometric parameters that have previously been identified as useful for GA estimation.</p><p><strong>Main outcome measures: </strong>A total of 189 equations that estimate GA based on foetal biometry were examined and compared with GA estimation based on foetal CRL. Comparisons between the observed GA and the estimated GA were made using R<sup>2</sup>, calibration slope and intercept. RMSE, mean difference and 95% range of error were also calculated.</p><p><strong>Results: </strong>A total of 2741 pregnant women were examined. After exclusions, 2339 participants were included. In the 20 best performing equations, the intercept ranged from -0.22 to 0.30, the calibration slope from 0.96 to 1.03 and the RSME from 0.67 to 0.87. Overall, multiparameter models outperformed single-parameter models. Both the 95% range of error and mean difference increased with gestation. Commonly used models based on measurement of the head circumference alone were not amongst the best performing models and were associated with higher 95% error and mean difference.</p><p><strong>Conclusions: </strong>We provide strong evidence that GA-specific equations based on multiparameter models should be used to estimate GA in late pregnancy. However, as all methods of GA assessment in late pregnancy are associated with large prediction intervals, efforts to improve access to early antenatal ultrasound must remain a priority.</p><p><strong>Trial registration: </strong>The proposal for this study and the corresponding methodological review was registered on PROSPERO international register of systematic reviews (registration number: CRD4201913776).</p>","PeriodicalId":50729,"journal":{"name":"Bjog-An International Journal of Obstetrics and Gynaecology","volume":null,"pages":null},"PeriodicalIF":4.7,"publicationDate":"2024-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141908153","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}