Psychiatry and Clinical Neurosciences Reports最新文献_第3页

Suicide of living kidney donor after recipient's graft organ failure: A case report 活体肾脏捐献者在受者移植器官衰竭后自杀：病例报告

Psychiatry and Clinical Neurosciences Reports Pub Date : 2024-03-01 DOI: 10.1002/pcn5.182

Tsuyoshi Okada, K. Otsuka, K. Shioda, Shiro Suda

引用次数: 0

Effects of the Mental Health Supporter Training Program on mental health‐related public stigma among Japanese people: A pretest/posttest study 心理健康支持者培训计划对日本人中与心理健康有关的公众耻辱感的影响：前测/后测研究

Psychiatry and Clinical Neurosciences Reports Pub Date : 2024-03-01 DOI: 10.1002/pcn5.176

M. Iida, Utako Sawada, Kentaro Usuda, Megumi Hazumi, Emi Okazaki, Kanako Ogura, M. Kataoka, N. Sasaki, Yasutaka Ojio, Asami Matsunaga, Ikue Umemoto, Miyuki Makino, Ayako Nakashita, Chiaki Kamikawa, Naoaki Kuroda, Hironori Kuga, Chiyo Fujii, Daisuke Nishi

{"title":"Effects of the Mental Health Supporter Training Program on mental health‐related public stigma among Japanese people: A pretest/posttest study","authors":"M. Iida, Utako Sawada, Kentaro Usuda, Megumi Hazumi, Emi Okazaki, Kanako Ogura, M. Kataoka, N. Sasaki, Yasutaka Ojio, Asami Matsunaga, Ikue Umemoto, Miyuki Makino, Ayako Nakashita, Chiaki Kamikawa, Naoaki Kuroda, Hironori Kuga, Chiyo Fujii, Daisuke Nishi","doi":"10.1002/pcn5.176","DOIUrl":"https://doi.org/10.1002/pcn5.176","url":null,"abstract":"The Mental Health Supporter Training Program is a national project conducted in Japan. This study aimed to determine the effects on mental health‐related stigma, mental health literacy, and knowledge about mental health difficulties and support techniques among program participants.The target population was local residents of a wide range of generations in Japan. Outcomes were assessed at baseline (T1), immediately postintervention (T2), and at the 6‐month follow‐up (T3). A mixed model for repeated‐measures conditional growth model analyses were employed to examine the effects of the intervention over time (T1, T2, T3). We also calculated effect sizes using Cohen's d.The program had a significantly favorable pooled effect on the Japanese version of the Reported and Intended Behaviour Scale score after adjusting for covariates (reported behavior [t = 3.20, p = 0.001]; intended behavior [t = 8.04, p < 0.001]). However, when compared at each time point, only intended behavior from T1 to T2 showed a significant difference (t = 8.37, p < 0.001). Significant pooled effects were found for mental health literacy (knowledge: t = 19.85, p < 0.001; attitude: t = 15.02, p < 0.001), knowledge of mental health (t = 28.04, p < 0.001), and psychological distress (t = −2.41, p = 0.016).The results suggest that the program might be effective for improving intended, but not reported, behavior in the short term and for improving mental health literacy, knowledge of mental health, and psychological distress.","PeriodicalId":507124,"journal":{"name":"Psychiatry and Clinical Neurosciences Reports","volume":"169 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140279600","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Beyond lecanemab: Examining Phase III potential in Alzheimer's therapeutics Lecanemab 之外：考察阿尔茨海默氏症疗法的 III 期潜力

Psychiatry and Clinical Neurosciences Reports Pub Date : 2024-03-01 DOI: 10.1002/pcn5.185

Hitoshi Osaka, Keiichiro Nishida, Tetsufumi Kanazawa

引用次数: 0

Anti‐LGI1 encephalitis preceded by psychiatric symptoms: A case report 先出现精神症状的抗LGI1脑炎病例报告

Psychiatry and Clinical Neurosciences Reports Pub Date : 2024-03-01 DOI: 10.1002/pcn5.181

Takuma Numazawa, R. Kobayashi, T. Shirata, T. Kondo, Hiroyasu Sato, Keiko Tanaka, Akihito Suzuki

{"title":"Anti‐LGI1 encephalitis preceded by psychiatric symptoms: A case report","authors":"Takuma Numazawa, R. Kobayashi, T. Shirata, T. Kondo, Hiroyasu Sato, Keiko Tanaka, Akihito Suzuki","doi":"10.1002/pcn5.181","DOIUrl":"https://doi.org/10.1002/pcn5.181","url":null,"abstract":"To date, only a few reports of anti‐LGI1 encephalitis with isolated psychiatric symptoms in the initial phase have been reported. We present a relatively rare case of antileucine‐rich glioma‐inactivated 1 (LGI1) encephalitis that developed only psychiatric symptoms at the onset.The patient was a male in his 40s who developed anxiety and panic symptoms and was started on antidepressants after being diagnosed with panic disorder by a psychiatrist. He visited our hospital 2 months later presenting with hallucinations, delusions, mild cognitive decline, and faciobrachial dystonic seizures in the left upper extremity and face. Fluid‐attenuated inversion recovery magnetic resonance imaging revealed swelling and hyperintensities in the right caudate nucleus and putamen. Cerebrospinal fluid analysis did not show increased protein levels or cell counts and revealed positive oligoclonal bands. Subsequently, positive results for anti‐LGI1 antibodies were observed in the cerebrospinal fluid. Therefore, the patient was diagnosed with anti‐LGI1 encephalitis.This case highlights the need to consider anti‐LGI1 encephalitis therapy in patients with acute‐onset psychiatric symptoms.","PeriodicalId":507124,"journal":{"name":"Psychiatry and Clinical Neurosciences Reports","volume":"37 9","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140267984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Late‐life mood disorder as the initial presentation of progressive supranuclear palsy: A case series 晚年情绪障碍是进行性核上性麻痹的最初表现：病例系列

Psychiatry and Clinical Neurosciences Reports Pub Date : 2024-02-21 DOI: 10.1002/pcn5.178

Kei Ichijo, K. Takahata, Shin Kurose, Takemi Watanabe, Yukihiro Nagase, H. Endo, K. Tagai, Makoto Ishitobi, Makoto Higuchi

{"title":"Late‐life mood disorder as the initial presentation of progressive supranuclear palsy: A case series","authors":"Kei Ichijo, K. Takahata, Shin Kurose, Takemi Watanabe, Yukihiro Nagase, H. Endo, K. Tagai, Makoto Ishitobi, Makoto Higuchi","doi":"10.1002/pcn5.178","DOIUrl":"https://doi.org/10.1002/pcn5.178","url":null,"abstract":"Progressive supranuclear palsy (PSP) is a rapidly progressive neurodegenerative disorder characterized by Parkinsonism, supranuclear ophthalmoplegia, postural instability, and cognitive impairment.This case series describes three patients initially diagnosed with late‐life mood disorders (depression and bipolar disorder) who were later diagnosed with PSP because of the development of typical neurological symptoms.The diagnostic challenge of PSP is highlighted in this case report, particularly in the early stages, when characteristic symptoms may not be present. The importance of considering PSP in the differential diagnosis of late‐life mood disorders, especially in the absence of response to standard antidepressant therapy, is also emphasized. The heterogeneity of PSP is described, with various subtypes and atypical variants presenting with different clinical features. The psychiatric symptoms of PSP include apathy, disinhibition, depression, and anxiety, whereas hallucinations and delusions are less frequent. Tau positron emission tomography imaging is discussed as a potential biomarker for atypical PSP.Early diagnosis and intervention are crucial for improved outcomes in PSP, necessitating further research to enhance the diagnostic and treatment strategies for PSP and other neurodegenerative diseases.","PeriodicalId":507124,"journal":{"name":"Psychiatry and Clinical Neurosciences Reports","volume":"2 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140442908","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Situational factors affecting abstinence from drugs: Panel data analysis of patients with drug use disorders in residential drug use treatment 影响戒毒的情境因素：对接受住院戒毒治疗的吸毒疾患患者的小组数据分析

Psychiatry and Clinical Neurosciences Reports Pub Date : 2024-02-20 DOI: 10.1002/pcn5.174

Satomi Mizuno, T. Shimane, Satoshi Inoura, Toshihiko Matsumoto

{"title":"Situational factors affecting abstinence from drugs: Panel data analysis of patients with drug use disorders in residential drug use treatment","authors":"Satomi Mizuno, T. Shimane, Satoshi Inoura, Toshihiko Matsumoto","doi":"10.1002/pcn5.174","DOIUrl":"https://doi.org/10.1002/pcn5.174","url":null,"abstract":"To identify situational factors that can predict drug abstention in patients with drug use disorders undergoing residential drug use treatment.Patients with drug use disorders admitted to drug addiction rehabilitation centers (DARCs) in 2016 were involved in this study. Longitudinal panel data were used, with eight follow‐up surveys over 6 years, approximately every 6 months. Of the 2752 samples from the eight follow‐up surveys, 2293 were analyzed as the complete panel data set. The primary outcome was drug abstention for approximately 6 months. The influences of situational factors during this period on the primary outcome were also assessed using a generalized linear mixed model in which inter‐individual differences were controlled as variable effects.The use of residential DARCs positively influenced the primary outcome (adjusted odds ratio [AOR] 3.33, 95% confidence interval [CI] 1.79–6.21) when compared to no DARC usage. The cessation of drinking also positively affected the primary outcome (AOR 3.10, 95% CI 1.79–4.62), while employment status (AOR 2.22, 95% CI 1.12–4.41) and the cessation of drinking (AOR 4.92, 95% CI 2.77–8.72) positively impacted the primary outcomes of patients not using DARCs.The use of residential DARCs and the cessation of drinking positively affected drug abstention rates. Employment and the cessation of drinking for patients who were not using the DARCs also had a positive effect. This information will aid in the development of social recovery strategies for people with drug use disorders.","PeriodicalId":507124,"journal":{"name":"Psychiatry and Clinical Neurosciences Reports","volume":"258 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140447033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Reduced dopamine transporter availability in drug‐naive adult attention‐deficit/hyperactivity disorder 药物过敏成人注意力缺陷/多动障碍中多巴胺转运体的可用性降低

Psychiatry and Clinical Neurosciences Reports Pub Date : 2024-02-18 DOI: 10.1002/pcn5.177

Shuntaro Itagaki, Takashi Ohnishi, Wataru Toda, Aya Sato, Junya Matsumoto, Hiroshi Ito, Shirou Ishii, Ryo Yamakuni, I. Miura, Hirooki Yabe

{"title":"Reduced dopamine transporter availability in drug‐naive adult attention‐deficit/hyperactivity disorder","authors":"Shuntaro Itagaki, Takashi Ohnishi, Wataru Toda, Aya Sato, Junya Matsumoto, Hiroshi Ito, Shirou Ishii, Ryo Yamakuni, I. Miura, Hirooki Yabe","doi":"10.1002/pcn5.177","DOIUrl":"https://doi.org/10.1002/pcn5.177","url":null,"abstract":"This study aimed to clarify the abnormalities in dopamine transporter (DAT) availability in drug‐naive adult patients with attention‐deficit/hyperactivity disorder (ADHD) and the relationship between ADHD symptoms and abnormalities in DAT availability.Single‐photon emission tomography (SPECT) was performed using iodine‐123‐β‐carbomethoxy‐3β‐(4‐iodophenyltropane) (I‐123 β CIT) as a tracer to measure in vivo DAT availability in 20 drug‐naive patients with ADHD [mean age ± standard deviation (SD)]: 25 ± 3.44 years; male:female = 11:9] and 20 age‐ and sex‐matched healthy controls (HCs) (mean age ± SD: 23.9 ± 2.27 years). Comparisons of DAT availability between HCs and adult patients with ADHD and the association between symptom severity and DAT availability within the ADHD group were analyzed using Statistical Parametric Mapping 12.Drug‐naive adults with ADHD showed significantly reduced DAT availability in the bilateral nucleus accumbens compared with HCs. Correlation analyses revealed a negative correlation between the severity of inattentive symptoms in adult patients with ADHD and DAT availability in the bilateral heads of the caudate nucleus, indicating the association between severe inattentive symptoms and lower DAT availability in the caudate nucleus.In drug‐naive adult patients with ADHD, DAT availability was reduced in the nucleus accumbens, an important part of the reward system. This finding indicates the importance of the DAT in the reward system in the pathogenesis of ADHD. Inattentiveness was associated with DAT availability in the caudate nucleus, suggesting involvement of the cortico‐striato‐thalamo‐cortical circuit.","PeriodicalId":507124,"journal":{"name":"Psychiatry and Clinical Neurosciences Reports","volume":"384 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140452781","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Preliminary observations on the associations between sensory processing abnormalities and event‐related potentials in adults with autism spectrum disorder 关于自闭症谱系障碍成人感觉处理异常与事件相关电位之间关系的初步观察

Psychiatry and Clinical Neurosciences Reports Pub Date : 2024-02-14 DOI: 10.1002/pcn5.173

Ryo Mizui, K. Yamamuro, Kosuke Okazaki, Mitsuhiro Uratani, Natsuko Kashida, Rio Ishida, M. Makinodan

{"title":"Preliminary observations on the associations between sensory processing abnormalities and event‐related potentials in adults with autism spectrum disorder","authors":"Ryo Mizui, K. Yamamuro, Kosuke Okazaki, Mitsuhiro Uratani, Natsuko Kashida, Rio Ishida, M. Makinodan","doi":"10.1002/pcn5.173","DOIUrl":"https://doi.org/10.1002/pcn5.173","url":null,"abstract":"Autism spectrum disorder (ASD) is a neurodevelopmental disorder that is thought to involve a variety of neurophysiological characteristics. Event‐related potentials (ERPs) reflect cognitive functions in the brain's cognitive processing. In this study, we investigated differences in P300 and N100 of ERPs between ASD and typically developing groups and focused on the relationship between the components of ERPs and measures of autistic traits and sensory processing characteristics.ERPs were measured in 96 subjects in the ASD group and 62 subjects in the age‐ and sex‐adjusted typically developing group. Correlations between each component and the scores of the Autism‐Spectrum Quotient Japanese version (AQ‐J) and the Adolescent and Adult Sensory Profile (AASP) were also evaluated.The ASD group showed a significant decrease in the amplitude of N100 at C3. Furthermore, a negative correlation was found between lower amplitude at C3 of N100 and low registered sensory scores in both groups.Our findings imply that the N100 amplitude at C3 could be a potential indicator for examining the neurophysiological traits of ASD; however, these results should be interpreted with caution due to their preliminary nature. These tentative insights into sensory processing anomalies may be discernible in specific subsets of the ASD population, providing a foundation for future investigative pathways.","PeriodicalId":507124,"journal":{"name":"Psychiatry and Clinical Neurosciences Reports","volume":"62 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139779394","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Preliminary observations on the associations between sensory processing abnormalities and event‐related potentials in adults with autism spectrum disorder 关于自闭症谱系障碍成人感觉处理异常与事件相关电位之间关系的初步观察

Psychiatry and Clinical Neurosciences Reports Pub Date : 2024-02-14 DOI: 10.1002/pcn5.173

Ryo Mizui, K. Yamamuro, Kosuke Okazaki, Mitsuhiro Uratani, Natsuko Kashida, Rio Ishida, M. Makinodan

{"title":"Preliminary observations on the associations between sensory processing abnormalities and event‐related potentials in adults with autism spectrum disorder","authors":"Ryo Mizui, K. Yamamuro, Kosuke Okazaki, Mitsuhiro Uratani, Natsuko Kashida, Rio Ishida, M. Makinodan","doi":"10.1002/pcn5.173","DOIUrl":"https://doi.org/10.1002/pcn5.173","url":null,"abstract":"Autism spectrum disorder (ASD) is a neurodevelopmental disorder that is thought to involve a variety of neurophysiological characteristics. Event‐related potentials (ERPs) reflect cognitive functions in the brain's cognitive processing. In this study, we investigated differences in P300 and N100 of ERPs between ASD and typically developing groups and focused on the relationship between the components of ERPs and measures of autistic traits and sensory processing characteristics.ERPs were measured in 96 subjects in the ASD group and 62 subjects in the age‐ and sex‐adjusted typically developing group. Correlations between each component and the scores of the Autism‐Spectrum Quotient Japanese version (AQ‐J) and the Adolescent and Adult Sensory Profile (AASP) were also evaluated.The ASD group showed a significant decrease in the amplitude of N100 at C3. Furthermore, a negative correlation was found between lower amplitude at C3 of N100 and low registered sensory scores in both groups.Our findings imply that the N100 amplitude at C3 could be a potential indicator for examining the neurophysiological traits of ASD; however, these results should be interpreted with caution due to their preliminary nature. These tentative insights into sensory processing anomalies may be discernible in specific subsets of the ASD population, providing a foundation for future investigative pathways.","PeriodicalId":507124,"journal":{"name":"Psychiatry and Clinical Neurosciences Reports","volume":"416 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139839419","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Is children'S mental health an important function of newly national organization for health crisis management in Japan? 儿童心理健康是日本新成立的全国健康危机管理组织的重要职能吗？

Psychiatry and Clinical Neurosciences Reports Pub Date : 2024-02-13 DOI: 10.1002/pcn5.175

M. Usami, Naoko Satake, H. Katsuyama, Kaori Okudera, Yumiko Uchiyama, Masatoshi Imamura, Tatsuro Hayakawa, Hidekatsu Yanai, N. Aoyanagi

引用次数: 0