Steven Menez, Kathleen F Kerr, Si Cheng, David Hu, Heather Thiessen-Philbrook, Dennis G Moledina, Sherry G Mansour, Alan S Go, T Alp Ikizler, James S Kaufman, Paul L Kimmel, Jonathan Himmelfarb, Steven G Coca, Chirag R Parikh
{"title":"Biomarker Panels for Predicting Progression of Kidney Disease in Acute Kidney Injury Survivors.","authors":"Steven Menez, Kathleen F Kerr, Si Cheng, David Hu, Heather Thiessen-Philbrook, Dennis G Moledina, Sherry G Mansour, Alan S Go, T Alp Ikizler, James S Kaufman, Paul L Kimmel, Jonathan Himmelfarb, Steven G Coca, Chirag R Parikh","doi":"10.2215/CJN.0000000622","DOIUrl":"10.2215/CJN.0000000622","url":null,"abstract":"","PeriodicalId":50681,"journal":{"name":"Clinical Journal of the American Society of Nephrology","volume":" ","pages":""},"PeriodicalIF":8.5,"publicationDate":"2024-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142820076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rachel E Patzer, Jade Buford, Megan Urbanski, Laura McPherson, Sudeshna Paul, Mengyu Di, Jessica L Harding, Goni Katz-Greenberg, Ana Rossi, Prince Mohan Anand, Amber Reeves-Daniel, Heather Jones, Laura Mulloy, Stephen O Pastan
{"title":"Reducing Disparities in Access to Kidney Transplantation Regional Study: A Randomized Trial in the Southeastern United States.","authors":"Rachel E Patzer, Jade Buford, Megan Urbanski, Laura McPherson, Sudeshna Paul, Mengyu Di, Jessica L Harding, Goni Katz-Greenberg, Ana Rossi, Prince Mohan Anand, Amber Reeves-Daniel, Heather Jones, Laura Mulloy, Stephen O Pastan","doi":"10.2215/CJN.0000000586","DOIUrl":"10.2215/CJN.0000000586","url":null,"abstract":"","PeriodicalId":50681,"journal":{"name":"Clinical Journal of the American Society of Nephrology","volume":" ","pages":""},"PeriodicalIF":8.5,"publicationDate":"2024-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142820079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sarah A van Eeghen, Natalie J Nokoff, Taryn G Vosters, Maartina J P Oosterom-Eijmael, David Z I Cherney, Irene G M van Valkengoed, Ye Ji Choi, Laura Pyle, Petter Bjornstad, Martin den Heijer, Daniël H van Raalte
{"title":"Unraveling Sex Differences in Kidney Health and CKD: A Review of the Effect of Sex Hormones.","authors":"Sarah A van Eeghen, Natalie J Nokoff, Taryn G Vosters, Maartina J P Oosterom-Eijmael, David Z I Cherney, Irene G M van Valkengoed, Ye Ji Choi, Laura Pyle, Petter Bjornstad, Martin den Heijer, Daniël H van Raalte","doi":"10.2215/CJN.0000000642","DOIUrl":"10.2215/CJN.0000000642","url":null,"abstract":"<p><p>Sexual dimorphism plays an important role in the pathogenesis and progression of CKD. Men with CKD often exhibit faster kidney function decline, leading to higher rates of kidney failure and mortality compared with women. Studies suggest that sex hormones may influence this apparent dimorphism, although the mechanisms underlying these influences remain poorly understood. In this review, we first summarize recent findings on sex differences in the prevalence and progression of CKD. Subsequently, we will focus on ( 1 ) the role of sex hormones in these sex differences, ( 2 ) kidney structural and hemodynamic differences between men and women, ( 3 ) the influence of sex hormones on pathophysiological processes leading to kidney disease, including glomerular hyperfiltration and key pathways involved in kidney inflammation and fibrosis, and finally, focus on the consequences of the underrepresentation of women in clinical trials. Understanding these sex differences is critical for advancing precision medicine and improving outcomes for both men and women with CKD.</p>","PeriodicalId":50681,"journal":{"name":"Clinical Journal of the American Society of Nephrology","volume":" ","pages":""},"PeriodicalIF":8.5,"publicationDate":"2024-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142820083","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mercedes A Munis, Qiaoling Chen, T Matthew Hill, Min Zhuo, Asher D Schachter, Simran K Bhandari, Aviv Hever, Teresa N Harrison, Ancilla W Fernandes, John J Sim
{"title":"Incidence and Proportion of Primary Focal Segmental Glomerulosclerosis (FSGS) among a Racially and Ethnically Diverse Adult Patient Population between 2010 and 2021.","authors":"Mercedes A Munis, Qiaoling Chen, T Matthew Hill, Min Zhuo, Asher D Schachter, Simran K Bhandari, Aviv Hever, Teresa N Harrison, Ancilla W Fernandes, John J Sim","doi":"10.2215/CJN.0000000590","DOIUrl":"10.2215/CJN.0000000590","url":null,"abstract":"","PeriodicalId":50681,"journal":{"name":"Clinical Journal of the American Society of Nephrology","volume":" ","pages":""},"PeriodicalIF":8.5,"publicationDate":"2024-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142407172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Todd A. Miano, Christina H.W. Brotman, Marc H. Scheetz, Michael G. S. Shashaty
{"title":"Impact of pseudo-nephrotoxicity on apparent acute kidney injury incidence and severity: a simulation study.","authors":"Todd A. Miano, Christina H.W. Brotman, Marc H. Scheetz, Michael G. S. Shashaty","doi":"10.2215/cjn.0000000623","DOIUrl":"https://doi.org/10.2215/cjn.0000000623","url":null,"abstract":"An abstract is unavailable. This article is available as a PDF only.","PeriodicalId":50681,"journal":{"name":"Clinical Journal of the American Society of Nephrology","volume":"9 1","pages":""},"PeriodicalIF":9.8,"publicationDate":"2024-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142776398","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Cancer Screening among Patients with Kidney Failure Requiring Hemodialysis: Where We Are and Where We Are Going.","authors":"Deepa Jayaram, Ladan Golestaneh","doi":"10.2215/CJN.0000000612","DOIUrl":"10.2215/CJN.0000000612","url":null,"abstract":"","PeriodicalId":50681,"journal":{"name":"Clinical Journal of the American Society of Nephrology","volume":" ","pages":"1521-1523"},"PeriodicalIF":8.5,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11637697/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142559302","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Dis-impede the Achievement of Euvolemia in Kidney Failure.","authors":"Sagar U Nigwekar, Michael J Cima","doi":"10.2215/CJN.0000000615","DOIUrl":"10.2215/CJN.0000000615","url":null,"abstract":"","PeriodicalId":50681,"journal":{"name":"Clinical Journal of the American Society of Nephrology","volume":"19 12","pages":"1518-1520"},"PeriodicalIF":8.5,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11637690/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142802992","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anitha Ramu, Rosalba Santana de Roberts, Nang San Hti Lar Seng, Gopisree Peringeth, Hana Rajevac, James M Pullman, Meryl Waldman, Ladan Golestaneh, Belinda Jim
{"title":"The Role of Repeat Kidney Biopsies in Lupus Nephritis in a Largely Black and Hispanic Population.","authors":"Anitha Ramu, Rosalba Santana de Roberts, Nang San Hti Lar Seng, Gopisree Peringeth, Hana Rajevac, James M Pullman, Meryl Waldman, Ladan Golestaneh, Belinda Jim","doi":"10.2215/CJN.0000000000000556","DOIUrl":"10.2215/CJN.0000000000000556","url":null,"abstract":"","PeriodicalId":50681,"journal":{"name":"Clinical Journal of the American Society of Nephrology","volume":" ","pages":"1643-1645"},"PeriodicalIF":8.5,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11637691/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142331748","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Michelle Tran, Chun Anna Xu, Jonathan Wilson, Rasheeda Hall, Patti L Ephraim, Tariq Shafi, Daniel E Weiner, Benjamin A Goldstein, Julia J Scialla
{"title":"Breast and Prostate Cancer Screening by Life Expectancy in Patients with Kidney Failure on Dialysis.","authors":"Michelle Tran, Chun Anna Xu, Jonathan Wilson, Rasheeda Hall, Patti L Ephraim, Tariq Shafi, Daniel E Weiner, Benjamin A Goldstein, Julia J Scialla","doi":"10.2215/CJN.0000000000000563","DOIUrl":"10.2215/CJN.0000000000000563","url":null,"abstract":"","PeriodicalId":50681,"journal":{"name":"Clinical Journal of the American Society of Nephrology","volume":" ","pages":"1537-1546"},"PeriodicalIF":8.5,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11637709/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142394955","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ana P Rossi, Goni Katz-Greenberg, Lisa Coscia, Carla W Brady, Christina Doligalski, Roxanna A Irani, Arthur Matas, Silvi Shah, Krista L Lentine
{"title":"Living Donation and Pregnancy-Related Complications: State of the Evidence and Call To Action for Improved Risk Assessment.","authors":"Ana P Rossi, Goni Katz-Greenberg, Lisa Coscia, Carla W Brady, Christina Doligalski, Roxanna A Irani, Arthur Matas, Silvi Shah, Krista L Lentine","doi":"10.2215/CJN.0000000593","DOIUrl":"10.2215/CJN.0000000593","url":null,"abstract":"<p><p>Living kidney donation and living liver donation significantly increases organ supply to make lifesaving transplants possible, offering survival benefits to the recipients and cost savings to society. Of all living donors, 40% are women of childbearing age. However, limited data exist regarding the effect of donation on future pregnancies and of pregnancy-related complications on postdonation outcomes. In February 2023, the American Society of Transplantation Women's Health Community of Practice held a virtual Controversies Conference on reproductive health, contraception, and pregnancy after transplantation and living donation. Experts in the field presented the available data. Smaller breakout sessions were created to discuss findings, identify knowledge gaps, and develop recommendations. We present the conference findings related to living donation. The evidence reviewed shows that gestational hypertension and gestational diabetes mellitus before kidney donation have been associated with an increased risk of developing postdonation hypertension and diabetes mellitus, respectively, without increasing the risk of developing an eGFR <45 ml/min after donation. The risk of preeclampsia in living kidney donors increases to 4%-10%, and low-dose aspirin may help reduce that risk. Little is known about the financial burden for living donors who become pregnant, their risk of postpartum depression, or the optimal time between donation and conception. The data on living liver donors are even scarcer. The creation of a registry of donor candidates may help answer many of these questions and, in turn, educate prospective donors so that they can make an informed choice.</p>","PeriodicalId":50681,"journal":{"name":"Clinical Journal of the American Society of Nephrology","volume":"19 12","pages":"1659-1670"},"PeriodicalIF":8.5,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11637692/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142802993","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}