Clinical Journal of the American Society of Nephrology最新文献

{"title":"Kidney PROTECTION after Cardiac Surgery with Intravenous Amino Acid Infusion.","authors":"Paul M Palevsky","doi":"10.2215/CJN.0000000678","DOIUrl":"10.2215/CJN.0000000678","url":null,"abstract":"","PeriodicalId":50681,"journal":{"name":"Clinical Journal of the American Society of Nephrology","volume":" ","pages":""},"PeriodicalIF":8.5,"publicationDate":"2025-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143371265","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Carbamylation and Anemia on the Association between Glycated Albumin and Kidney Outcomes in Diabetic Kidney Disease.","authors":"Mengyao Tang, Anders Berg, Hui Zheng, Sahir Kalim","doi":"10.2215/CJN.0000000663","DOIUrl":"10.2215/CJN.0000000663","url":null,"abstract":"","PeriodicalId":50681,"journal":{"name":"Clinical Journal of the American Society of Nephrology","volume":" ","pages":""},"PeriodicalIF":8.5,"publicationDate":"2025-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143371161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Psychosocial Health in Mexican Adults with CKD Living in Chicago versus Mexico City.","authors":"Madison Pineda, Ana K Fernández-Yepez, Arabela Quiroga Gomez, Claire T Larkin, Celestin Missikpode, Amatur Amarah, Eunice Carmona-Powell, Natalie Meza, Michael J Fischer, Ana C Ricardo, Magdalena Madero, James P Lash","doi":"10.2215/CJN.0000000637","DOIUrl":"10.2215/CJN.0000000637","url":null,"abstract":"","PeriodicalId":50681,"journal":{"name":"Clinical Journal of the American Society of Nephrology","volume":" ","pages":""},"PeriodicalIF":8.5,"publicationDate":"2025-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143366655","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sex and Gender in Science, Medicine, and Nephrology: Where Are We and Why Does It Matter?","authors":"Farah Wehbe, Adeera Levin","doi":"10.2215/cjn.0000000677","DOIUrl":"https://doi.org/10.2215/cjn.0000000677","url":null,"abstract":"An abstract is unavailable. This article is available as a PDF only.","PeriodicalId":50681,"journal":{"name":"Clinical Journal of the American Society of Nephrology","volume":"50 1","pages":""},"PeriodicalIF":9.8,"publicationDate":"2025-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143192027","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bridging the Gap: Assessing Nephrology Transition Practices in Pediatric and Adult Medical Centers","authors":"Andrew Vissing, Priya S Verghese, Angelina Dixon, Cybele Ghossein","doi":"10.2215/cjn.0000000639","DOIUrl":"https://doi.org/10.2215/cjn.0000000639","url":null,"abstract":"cols in academic medical centers, however, is currently unknown. Methods: General nephrology and transplant nephrology programs were surveyed at both pediatric and adult medical centers to explore the current state of nephrology transition practices. Programs without transition clinics were asked to identify obstacles preventing the establishment of a transition clinic. Results: Overall, there were 488 programs targeted for survey distribution. There were 188 survey responses with an overall response rate of 39%. Only 20% of programs had a transition clinic and 32% of programs reported neither having an established transition clinic nor a transition protocol. Adult programs were more likely to lack an established transition clinic or protocol compared to pediatric programs (42% vs 20%, P = 0.001). Of partnered pediatric and adult programs that both responded to the survey, 51% were discordant in their transition practices. For the 150 programs without a transition clinic, there were 119 comments regarding obstacles to the establishment of such a clinic. Resource and financial obstacles were mentioned the most frequently (50% of comments). Adult programs were more likely to mention no perceived need or obstacles compared to pediatric programs (17% vs 4%, P = 0.04). Conclusions: Despite guidelines recommending pediatric to adult transition programs for young adults with kidney disease, transition clinics remain uncommon. While there are many cited barriers to the establishment of a nephrology transition clinic, our study highlights the lack of coordination and cooperation between adult and pediatric centers which may stem from a lack of perceived need or interest from adult nephrology programs. Copyright © 2025 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of the American Society of Nephrology...","PeriodicalId":50681,"journal":{"name":"Clinical Journal of the American Society of Nephrology","volume":"136 1","pages":""},"PeriodicalIF":9.8,"publicationDate":"2025-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143192025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of Urinary PGE2 with Plasma Potassium in Patients with CKD and the General Population.","authors":"Frank Geurts, Martin Gritter, Dominique M Bovée, Rosa D Wouda, Liffert Vogt, Layal Chaker, Robert A Fenton, Ewout J Hoorn","doi":"10.2215/CJN.0000000653","DOIUrl":"10.2215/CJN.0000000653","url":null,"abstract":"","PeriodicalId":50681,"journal":{"name":"Clinical Journal of the American Society of Nephrology","volume":" ","pages":""},"PeriodicalIF":8.5,"publicationDate":"2025-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143071165","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Health Equity and Artificial Intelligence in Nephrology.","authors":"Adam Engel Hercz,Susanne B Nicholas,Alex A T Bui,Keith C Norris","doi":"10.2215/cjn.0000000673","DOIUrl":"https://doi.org/10.2215/cjn.0000000673","url":null,"abstract":"","PeriodicalId":50681,"journal":{"name":"Clinical Journal of the American Society of Nephrology","volume":"28 1","pages":""},"PeriodicalIF":9.8,"publicationDate":"2025-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143056899","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Performance of Creatinine and Cystatin-Based Equations on Estimating Measured Glomerular Filtration Rate in People with Hematological and Solid Cancers.","authors":"Silvia M Titan,John C Lieske,Jeffrey W Meeusen,Stacy Thorson,Yi Lin,Grzegorz S Nowakowski,Jason N Barreto,Erin F Barreto,Kathryn J Ruddy,Nelson Leung,Andrew D Rule,Sandra M Herrmann","doi":"10.2215/cjn.0000000616","DOIUrl":"https://doi.org/10.2215/cjn.0000000616","url":null,"abstract":"BACKGROUNDGlomerular filtration rate (GFR) assessment is important in clinical practice, with implications for diagnosis, prognostication, and drug dosing. People with cancer are at risk of imprecision in GFR estimation. This cross-sectional study evaluated the performance of various creatinine and cystatin C-based equations in comparison to measured GFR (mGFR) in people with cancer.METHODSWe retrieved data for all adult patients who had mGFR by urinary iothalamate clearance between 2011 and 2023 at Mayo Clinic and use of an electronic health record diagnosis code for cancer within two years prior to mGFR. The Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI), European Kidney Function Consortium (EKFC), and Cockcroft-Gault (CG) equations were computed, along with performance metrics (bias, precision, and root mean square error, RMSE). Confidence intervals were generated by bootstrapping and analysis were stratified by solid and hematological cancer.RESULTSFrom all adults with cancer and mGFR, 1145 had both creatinine and cystatin C available within seven days of mGFR. Among all equations, the creatinine- cystatin C CKDEPI equation provided the best performance, with small bias (median 3.0, 95%CI 2.3-3.8) and higher precision (RMSE 14.5) compared to creatinine-only or cystatin-only equations (RMSE varying from 16.6 to 20), and this was also true in solid and hematological cancers. The creatinine-cystatin EKFC equation had a similar performance to CKDEPI, CG showed worst precision (30% of people with errors above 30%), and cystatin C CKDEPI equation was the most biased, prone to underestimation of mGFR.CONCLUSIONSIn our cohort of patients with mGFR and cancer, the CKDEPI creatinine-cystatin C equation performed best for GFR assessment, and this was true for both solid and hematological cancers. Our findings give support for the preferential use of creatinine and cystatin C-based equations instead of creatinine-only or cystatin C-only equations in people with cancer.","PeriodicalId":50681,"journal":{"name":"Clinical Journal of the American Society of Nephrology","volume":"39 1","pages":""},"PeriodicalIF":9.8,"publicationDate":"2025-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143056898","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of Race on Transplantation in Autosomal Dominant Polycystic Kidney Disease.","authors":"Sambhavi Krishnamoorthy,Niveditha Girimaji Satishchandra,Arlene Chapman,Rita McGill","doi":"10.2215/cjn.0000000626","DOIUrl":"https://doi.org/10.2215/cjn.0000000626","url":null,"abstract":"BACKGROUNDAutosomal dominant polycystic kidney disease (ADPKD) is the most common genetic cause of end-stage kidney disease (ESKD) and occurs without racial predilection. In general, non-White ESKD patients have less access to transplantation, especially living donor transplantation. We examined long-term outcomes of ADPKD-ESKD patients by self-reported race, with attention to the trajectory of Estimated Post-Transplant Survival (EPTS) scores over time.METHODSUnited Network for Organ Sharing Standard Transplant Analysis and Research files were used to identify 32,611 ADPKD transplant recipients between 1/2000-12/2022. EPTS scores were calculated from the date of waitlisting until transplantation occurred. Cumulative incidences of living and deceased transplantation were calculated and plotted. Cox models were made for graft failure and death, and a sub-distribution hazards model for graft failure accounted for death as a competing outcome, with adjustment for patient, donor, and transplant factors.RESULTSCompared to White ADPKD patients, all other groups had more dialysis years, more delayed graft function, and fewer living and pre-emptive transplants; mean EPTS scores were lower in African American (AA) and Hispanic patients at each timepoint on the waitlist. However, EPTS scores at the time of transplant was less likely to be <20% in AA and Hispanic patients, due to longer waiting time. AA patients had a significantly higher risk of graft failure with death as competing risk compared to White patients. Asian and Hispanic patients had similar graft survivals but better patient survival compared to White patients.CONCLUSIONSWaitlist experience, allograft quality, and post-transplant outcomes of patients with ADPKD are influenced by patient race.","PeriodicalId":50681,"journal":{"name":"Clinical Journal of the American Society of Nephrology","volume":"7 1","pages":""},"PeriodicalIF":9.8,"publicationDate":"2025-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143056906","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessing Current Nephrology Fellows' Perceptions of Future Earnings as Attending Physicians.","authors":"Rasha Raslan, Kurtis A Pivert, Jefferson L Triozzi, Suzanne M Boyle","doi":"10.2215/CJN.0000000645","DOIUrl":"10.2215/CJN.0000000645","url":null,"abstract":"","PeriodicalId":50681,"journal":{"name":"Clinical Journal of the American Society of Nephrology","volume":" ","pages":""},"PeriodicalIF":8.5,"publicationDate":"2025-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143029798","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}