{"title":"A critical appraisal and methodological inquiry into an automated multimodal deep learning model for predicting biochemical recurrence in prostate cancer","authors":"Parth Aphale , Shashank Dokania , Himanshu Shekhar","doi":"10.1016/j.clinimag.2025.110615","DOIUrl":"10.1016/j.clinimag.2025.110615","url":null,"abstract":"","PeriodicalId":50680,"journal":{"name":"Clinical Imaging","volume":"127 ","pages":"Article 110615"},"PeriodicalIF":1.5,"publicationDate":"2025-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145082437","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical ImagingPub Date : 2025-09-11DOI: 10.1016/j.clinimag.2025.110613
Hinpetch Daungsupawong , Viroj Wiwanitkit
{"title":"Large language models for imaging modality selection: Comment","authors":"Hinpetch Daungsupawong , Viroj Wiwanitkit","doi":"10.1016/j.clinimag.2025.110613","DOIUrl":"10.1016/j.clinimag.2025.110613","url":null,"abstract":"<div><div>This correspondence discuss on published article and shows future direction.</div></div>","PeriodicalId":50680,"journal":{"name":"Clinical Imaging","volume":"127 ","pages":"Article 110613"},"PeriodicalIF":1.5,"publicationDate":"2025-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145076491","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical ImagingPub Date : 2025-09-10DOI: 10.1016/j.clinimag.2025.110612
Ami Gokli , Clay Oliver , Cory M. Pfeifer
{"title":"US news & world report children's hospital assessments: The role of radiology","authors":"Ami Gokli , Clay Oliver , Cory M. Pfeifer","doi":"10.1016/j.clinimag.2025.110612","DOIUrl":"10.1016/j.clinimag.2025.110612","url":null,"abstract":"","PeriodicalId":50680,"journal":{"name":"Clinical Imaging","volume":"127 ","pages":"Article 110612"},"PeriodicalIF":1.5,"publicationDate":"2025-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145087993","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical ImagingPub Date : 2025-09-10DOI: 10.1016/j.clinimag.2025.110614
Eren Çamur , Turay Cesur , Yasin Celal Güneş , Yusuf Öztürk , Yunus Şerefettin , Ersin Doğanözü , Ayşegül Akçebe , Ahmet Kürşad Güneş , İbrahim Ethem Cakcak
{"title":"Reply: clinical imaging large language models for imaging modality selection: comment","authors":"Eren Çamur , Turay Cesur , Yasin Celal Güneş , Yusuf Öztürk , Yunus Şerefettin , Ersin Doğanözü , Ayşegül Akçebe , Ahmet Kürşad Güneş , İbrahim Ethem Cakcak","doi":"10.1016/j.clinimag.2025.110614","DOIUrl":"10.1016/j.clinimag.2025.110614","url":null,"abstract":"","PeriodicalId":50680,"journal":{"name":"Clinical Imaging","volume":"127 ","pages":"Article 110614"},"PeriodicalIF":1.5,"publicationDate":"2025-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145066611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical ImagingPub Date : 2025-09-10DOI: 10.1016/j.clinimag.2025.110611
Melissa Reichman , Lori Deitte , Thomas S.C. Ng , Elizabeth Arleo , Kirti Magudia
{"title":"American association for women in radiology (AAWR): Official statement regarding paid family and medical leave (PFML)","authors":"Melissa Reichman , Lori Deitte , Thomas S.C. Ng , Elizabeth Arleo , Kirti Magudia","doi":"10.1016/j.clinimag.2025.110611","DOIUrl":"10.1016/j.clinimag.2025.110611","url":null,"abstract":"<div><div>Physician well-being is essential to high-quality patient care, yet the lack of universally available paid family and medical leave (PFML) in the United States undermines this principle. The dynamic interplay between work and personal responsibilities—especially during significant life events such as childbirth, illness, or caregiving—can impact healthcare providers' mental and physical health, ultimately affecting patient outcomes. While the Family and Medical Leave Act (FMLA) provides unpaid, job-protected leave, it excludes many workers and disproportionately impacts women, minorities, and low-income families. Extensive evidence shows that PFML improves maternal and child health, increases workforce retention, and supports equity in the medical profession. Medical societies, including the American College of Radiology (ACR), American Board of Radiology (ABR), and others have recognized the critical need for consistent PFML policies. In alignment with these efforts, the American Association for Women Radiologists (AAWR) recommends that departments, practices, and training programs in diagnostic radiology, interventional radiology, radiation oncology, medical physics, and nuclear medicine provide a minimum of 12 weeks of paid family/medical leave within a 12-month period for attending physicians, medical physicists, and trainees. The AAWR further advocates for institutional support measures such as protected lactation time, subsidized childcare, and flexible promotion policies to ensure equitable implementation. Establishing national PFML standards across medical specialties would align healthcare systems with the principles they promote for patients, fostering a more diverse, inclusive, and resilient workforce. A multi-tiered advocacy approach—from academic departments to specialty boards offers a roadmap to achieving this longoverdue reform.</div></div>","PeriodicalId":50680,"journal":{"name":"Clinical Imaging","volume":"127 ","pages":"Article 110611"},"PeriodicalIF":1.5,"publicationDate":"2025-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145088047","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical ImagingPub Date : 2025-09-09DOI: 10.1016/j.clinimag.2025.110618
R. Jared Weinfurtner , Dana Ataya , Kimberly Funaro , Asha Bhatt , Mahmoud Abdalah , Olya Stringfield , Natarajan Raghunand , Zachary Thompson , Marie C. Lee , Brian Czerniecki , Aixa Soyano Muller , Hatem Soliman , Hyo Han
{"title":"Quantitative habitat concentration analysis of triple negative breast cancer on MRI correlates with pathologic response to combination neoadjuvant immuno/chemotherapy","authors":"R. Jared Weinfurtner , Dana Ataya , Kimberly Funaro , Asha Bhatt , Mahmoud Abdalah , Olya Stringfield , Natarajan Raghunand , Zachary Thompson , Marie C. Lee , Brian Czerniecki , Aixa Soyano Muller , Hatem Soliman , Hyo Han","doi":"10.1016/j.clinimag.2025.110618","DOIUrl":"10.1016/j.clinimag.2025.110618","url":null,"abstract":"<div><h3>Objective</h3><div>To determine if quantitative volumetric habitat concentration analysis of triple negative breast cancer (TNBC) on pre-treatment MRI correlates with neoadjuvant treatment response in patients treated with combination Talimogene Laherparepvec (TVEC) neoadjuvant immunotherapy and chemotherapy (NAIC).</div></div><div><h3>Methods</h3><div>Patients with TNBC in a single institution phase I/II trial from 5/2017–9/2020 underwent pre-treatment breast MRI followed by ultrasound-guided intratumoral TVEC injections and NAC prior to surgery. Pre-treatment MRIs were evaluated quantitatively using functional tumor volume (FTV) assessment and temporal voxel intensity categorization (high vs low plus phase of peak) to establish percentage habitat concentrations (%HC) for each quantitative method. These were correlated with pathologic response at surgery. Statistical analyses were performed using Mann Whitney U and comparison of proportions tests, with <em>p</em> < 0.05 considered statistically significant.</div></div><div><h3>Results</h3><div>Twenty-five female patients, aged 32–66 (avg 49), were included. Average %FTV and %High-Enhancement Volume (HEV) was 75.7 % and 87.1 %, respectively. Twelve patients (48 %) achieved pCR. On average, patients achieving pCR had higher %FTV (84.8 % vs 67.4 %, <em>p</em> = 0.022) and %HEV (93.3 % vs 81.3 %, <em>p</em> = 0.010). Patients with %HC above average for FTV and HEV also had lower average percent tumor cellularity (TC, 1 and 1.1 % vs 14.3 and 17.1 %, <em>p</em> = 0.023 and 0.003, respectively). Indeed, tumors with above average %FTV and %HEV achieved pCR in 71 % (10/14) and 69 % (11/16), respectively. In contrast, those below average achieved pCR in only 18 % (2/11) and 11 % (1/9), with <em>p</em> = 0.008 and 0.006, respectively.</div></div><div><h3>Conclusion</h3><div>Above-average concentration of functional tumor/high enhancement voxels within tumors before NAIC correlates with higher pCR rates and lower %TC at surgery.</div></div>","PeriodicalId":50680,"journal":{"name":"Clinical Imaging","volume":"127 ","pages":"Article 110618"},"PeriodicalIF":1.5,"publicationDate":"2025-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145050246","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical ImagingPub Date : 2025-09-05DOI: 10.1016/j.clinimag.2025.110606
D. Hussain , A. Saad , S.R. Pellakuru , K. Shirodkar , K.P. Iyengar , S. Evans , R. Botchu
{"title":"Tumours of the ischiofemoral region: The largest case series","authors":"D. Hussain , A. Saad , S.R. Pellakuru , K. Shirodkar , K.P. Iyengar , S. Evans , R. Botchu","doi":"10.1016/j.clinimag.2025.110606","DOIUrl":"10.1016/j.clinimag.2025.110606","url":null,"abstract":"<div><h3>Introduction</h3><div>The ischiofemoral space (IFS) has gained increasing clinical recognition as a rare source of extra-articular hip pain in cases of ischiofemoral Impingement (IFI). This study presents the largest case series of primary tumours arising in the IFS and aims to provide a descriptive review of the varying lesions that can affect this anatomical region.</div></div><div><h3>Materials and methods</h3><div>A retrospective study at our tertiary orthopaedic oncology unit was conducted, utilising our radiology and oncology databases, as well as the Picture Archiving and Communication System (PACS), to identify all tumours localised in the IFS over 24 years.</div></div><div><h3>Results</h3><div>From our database, we identified 34 lesions involving the IFS. Among the 34 lesions, 21 were bone and 13 were soft tissue. Of the 21 bone lesions, 19 were benign and 2 were malignant. The most common benign bone lesion identified was osteochondroma (<em>n</em> = 18), whereas the only malignant bone lesion was chondrosarcoma (<em>n</em> = 2). 8 soft tissue lesions were benign, and 5 were malignant. The predominant soft tissue lesion were atypical lipomatous tumours (<em>n</em> = 4), whereas the most prevalent malignant soft tissue lesion was spindle cell sarcoma (n = 4).</div></div><div><h3>Conclusion</h3><div>Our findings highlight the diversity of lesions encountered, including benign and malignant tumours. The variability in presentation, diagnosis, and management underscores the need for careful imaging and surgical planning.</div></div>","PeriodicalId":50680,"journal":{"name":"Clinical Imaging","volume":"127 ","pages":"Article 110606"},"PeriodicalIF":1.5,"publicationDate":"2025-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145027768","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical ImagingPub Date : 2025-09-03DOI: 10.1016/j.clinimag.2025.110607
Teymour Sadrieh , Anas S. Al-Smadi , Ali Shaibani , Ramez N. Abdalla , Sameer A. Ansari , Donald Cantrell
{"title":"Fluoroscopic guided percutaneous sacroplasty utilizing a single curved needle: technical notes","authors":"Teymour Sadrieh , Anas S. Al-Smadi , Ali Shaibani , Ramez N. Abdalla , Sameer A. Ansari , Donald Cantrell","doi":"10.1016/j.clinimag.2025.110607","DOIUrl":"10.1016/j.clinimag.2025.110607","url":null,"abstract":"<div><h3>Purpose</h3><div>Percutaneous sacroplasty is the current standard of care for the management of painful sacral insufficiency fractures, and has proven to provide significant pain relief and functional improvement for patients. Currently, there is no widely accepted standard technique for sacroplasty. In this study, we describe a new fluoroscopy guided technique using a single curved needle to treat sacral insufficiency fractures at any sacral level.</div></div><div><h3>Methods</h3><div>This is a retrospective case series and technical notes. A retrospective review of the pre-operative notes, procedure reports, and post-operative clinic visits was performed. Parameters recorded were pre-operative pain score, comorbidities, procedure details including radiation dose and duration, complications, and postoperative outcomes.</div></div><div><h3>Results</h3><div>From January 2023 to June 2024, four curved needle sacroplasties were performed on three patients (two females, one male) at our institution: two for bilateral sacral fractures in a single patient, one for a left sacral fracture, and one for a right sacral fracture. Patient ages ranged from 58 to 90. The average fluoroscopy time was 19.5 min (range: 13.7–24.9 min), and the average radiation dose was 774.8 mGy (range: 622.1–1027 mGy). No procedural complications were observed. Postoperatively, there was good functional improvement for all patients and VAS scores dropped by an average of 5.5 points, reflecting significant pain relief.</div></div><div><h3>Conclusions</h3><div>Percutaneous sacroplasty utilizing a curved needle is a novel technique for treating sacral insufficiency fractures. This technique allows the ability to inject cement in various directions with a single needle. This approach potentially reduces procedural time and radiation exposure.</div></div>","PeriodicalId":50680,"journal":{"name":"Clinical Imaging","volume":"127 ","pages":"Article 110607"},"PeriodicalIF":1.5,"publicationDate":"2025-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145076488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical ImagingPub Date : 2025-08-28DOI: 10.1016/j.clinimag.2025.110595
Arthur Santos Lima , Beatriz de Carvalho Villela , Hugo Nunes Pustilnik , Beatriz Dacach Assis , Jorge Andion Torreão , Luiz Eduardo Fonteles Ritt
{"title":"Prognostic value of incidental coronary artery calcium detected on routine chest computed tomography: A systematic review and meta-analysis","authors":"Arthur Santos Lima , Beatriz de Carvalho Villela , Hugo Nunes Pustilnik , Beatriz Dacach Assis , Jorge Andion Torreão , Luiz Eduardo Fonteles Ritt","doi":"10.1016/j.clinimag.2025.110595","DOIUrl":"10.1016/j.clinimag.2025.110595","url":null,"abstract":"<div><h3>Background</h3><div>To evaluate the prognostic value of incidental coronary artery calcium (CACi) identified on routine chest computed tomography (CT) scans in predicting cardiovascular outcomes and its association with statin prescription in asymptomatic individuals.</div></div><div><h3>Methods</h3><div>We searched MEDLINE/PubMed, EMBASE, and Cochrane Library for randomized clinical trials, prospective cohort studies, and retrospective cohort studies. Search terms included combinations of “CT,” “routine,” “thorax,” “coronary,” and “calcification. The primary outcomes were cardiovascular mortality and statin initiation in asymptomatic patients with incidental CAC detected on routine chest CT. Statistical analysis was performed using the R software, specifically version 4.3.2.Outcomes included cardiovascular mortality and major adverse cardiovascular events (MACE). Secondary outcomes included statin initiation and medication adherence as reported by each study.</div></div><div><h3>Results</h3><div>67,127 patients were included from 7 studies, of which 4 were RCT. Follow up ranged from 6 to 135 months and the prevalence of male participants was 86 %. The results indicated a significantly higher likelihood of cardiovascular mortality in the group with incidental CAC presence (OR: 7.38, 95 % CI: 4.10–13.28, <em>p</em> < 0.001). Heterogeneity was considered moderate, with an I<sup>2</sup> of 45 % and a Chi<sup>2</sup> of 7.26.</div></div><div><h3>Conclusions</h3><div>Incidental coronary artery calcium quantification on routine chest computed tomography is a valuable tool for cardiovascular risk stratification, and the detection of incidental coronary arterial calcium is related with and increased risk of cardiovascular mortality.</div></div>","PeriodicalId":50680,"journal":{"name":"Clinical Imaging","volume":"126 ","pages":"Article 110595"},"PeriodicalIF":1.5,"publicationDate":"2025-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144922918","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Vendor-neutral MR bone imaging in musculoskeletal imaging","authors":"Tomohiro Nakamura , Akitoshi Inoue , Tatsuya Oki , Shin Kato , Yoshiyuki Watanabe","doi":"10.1016/j.clinimag.2025.110598","DOIUrl":"10.1016/j.clinimag.2025.110598","url":null,"abstract":"<div><div>A vendor-neutral MR bone imaging technique based on 3D time-of-flight MR angiography with spoiled gradient recalled acquisition in the steady state (TOF-SPGR) was developed to enhance the depiction of bone and calcification/ossification. This approach is independent of scanner manufacturer and application type, enabling reduced radiation exposure by replacing or triaging further CT examinations. This article describes the optimization of scan parameters for clinical musculoskeletal protocols and explores its clinical applications with representative cases.</div></div>","PeriodicalId":50680,"journal":{"name":"Clinical Imaging","volume":"126 ","pages":"Article 110598"},"PeriodicalIF":1.5,"publicationDate":"2025-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144925585","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}