Clinical Journal of Pain最新文献

{"title":"Exploration of Somatosensory Function of Patients With Acute Nonspecific Neck Pain, Through Quantitative Sensory Testing and Self-reported Symptoms.","authors":"Jente Bontinck,&nbsp;Marjolein Chys,&nbsp;Iris Coppieters,&nbsp;Mira Meeus,&nbsp;Barbara Cagnie","doi":"10.1097/AJP.0000000000001131","DOIUrl":"https://doi.org/10.1097/AJP.0000000000001131","url":null,"abstract":"<p><strong>Objectives: </strong>Adaptations in somatosensory function characterize several chronic pain conditions, including nonspecific neck pain (NNP). Early signs of central sensitization (CS) contribute to pain chronification and poor treatment responses after conditions such as whiplash injury and low back pain. Despite this well-established association, the prevalence of CS in patients with acute NNP, and accordingly, the potential impact of this association, is still unclear. Therefore, this study aimed to investigate whether changes in somatosensory function occur during the acute phase of NNP.</p><p><strong>Methods: </strong>This cross-sectional study compared 35 patients with acute NNP with 27 pain-free individuals. All participants completed standardized questionnaires and an extensive multimodal Quantitative Sensory Testing protocol. A secondary comparison was made with 60 patients, with chronic whiplash-associated disorders, a population wherein CS is well-established.</p><p><strong>Results: </strong>Compared with pain-free individuals, pressure pain thresholds (PPTs) in remote areas and thermal detection and pain thresholds were unaltered. However, patients with acute NNP showed lower cervical PPTs and conditioned pain modulation, higher temporal summation, Central Sensitization Index scores, and pain intensity. Compared with the group with chronic whiplash-associated disorders, PPTs did not differ at any location, yet the Central Sensitization Index scores were lower.</p><p><strong>Discussion: </strong>Changes in somatosensory function occur already in acute NNP. Local mechanical hyperalgesia demonstrated peripheral sensitization, while enhanced pain facilitation, impaired conditioned pain modulation, and self-reported symptoms of CS suggest adaptations in pain processing already early in the stage of NNP.</p>","PeriodicalId":50678,"journal":{"name":"Clinical Journal of Pain","volume":"39 8","pages":"377-385"},"PeriodicalIF":2.9,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9914817","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bridging Access to Pediatric Pain Care: Telehealth Utilization.","authors":"Amber M Sepsey,&nbsp;Olivia E Sokol,&nbsp;Samantha E Huestis,&nbsp;Rashmi P Bhandari","doi":"10.1097/AJP.0000000000001132","DOIUrl":"https://doi.org/10.1097/AJP.0000000000001132","url":null,"abstract":"Objectives: To evaluate subsequent shifts to patient access to tertiary pain management care following shelter-in-place (SIP) and increased telehealth during the COVID-19 pandemic. Materials and Methods: Retrospective naturalistic design was used. Data for this study were extracted from a retrospective review of the Pediatric-Collaborative Health Outcomes Information Registry, with additional demographic information collected using chart review. Participants were 906 youth who received an initial evaluation either in-person (n=472) within the 18 months before SIP or through telehealth (n=434) within the 18 months after SIP during the COVID-19 pandemic. Patient variables to assess access included geographic distance from the clinic, ethnic and racial diversity, and patient’s insurance type. Descriptive characteristics for each group were analyzed using χ2 test, percentage change, and t-test analyses. Results: Data indicated that transitioning to telehealth resulted in maintained access rates between groups as measured by race and ethnic diversity as well as distance traveled from the clinic. A trend toward increase in government-funded insurance was found, though no statistically significant differences were identified between telehealth and in-person visits. Though the majority of participants (in-person: 52.75%; telehealth 55.81%) lived within 50 miles of the clinic, results indicated that telehealth allowed for a statistically significant increase in evaluation access for families living further from the clinic within a 50-mile radius. Discussion: Overall, accessibility to pediatric pain management through telehealth during SIP was maintained despite significant declines in overall access to health care, with some trends in increased accessibility for patients with government insurance.","PeriodicalId":50678,"journal":{"name":"Clinical Journal of Pain","volume":"39 8","pages":"408-413"},"PeriodicalIF":2.9,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9861601","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Role of Benefit Finding in the Relationship Between Pain and Posttraumatic Stress Symptoms in Youth With Chronic Pain: A Longitudinal Analysis.","authors":"Jamie Kaufhold,&nbsp;Sabine Soltani,&nbsp;Kathryn A Birnie,&nbsp;Melanie Noel","doi":"10.1097/AJP.0000000000001127","DOIUrl":"https://doi.org/10.1097/AJP.0000000000001127","url":null,"abstract":"<p><strong>Objectives: </strong>Chronic pain and posttraumatic stress symptoms (PTSS) co-occur in youth at high rates. Current conceptual models of mutual maintenance do not identify specific youth resilience factors, such as benefit finding in this co-occurrence. Benefit finding is the process of perceiving positive benefits as the results of experiencing adversity. It has been viewed as a potential mitigator for illness symptoms; however, only minimal cross-sectional research has been conducted and none has longitudinally examined the possible buffering effect of benefit finding in the co-occurrence of chronic pain and PTSS in youth. This longitudinal investigation examined whether benefit finding changes over time, influences pain outcomes and moderates the relationship between PTSS and chronic pain in a clinical sample of youth with chronic pain.</p><p><strong>Methods: </strong>Youth ( N =105, Female = 78.1%) with chronic pain between the ages of 7-17 years ( M = 13.70; SD = 2.47) participated. Participants completed measures at baseline, 3 months, and 6 months to assess pain intensity and interference, PTSS, and benefit finding.</p><p><strong>Results: </strong>Benefit finding did not significantly change over time. Cross-sectionally, benefit finding at 3 months significantly explained the variance in pain interference and intensity at 3 months. Benefit finding at 3 months did not significantly moderate the relationship between baseline PTSS and pain interference or intensity at 6 months.</p><p><strong>Discussion: </strong>These findings replicate previous research that found positive cross-sectional associations between PTSS and chronic pain, and between benefit finding and worse pain intensity and interference. Further research on resilience in pediatric chronic pain is needed.</p>","PeriodicalId":50678,"journal":{"name":"Clinical Journal of Pain","volume":"39 8","pages":"367-376"},"PeriodicalIF":2.9,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9858113","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association Between Activity Pacing and Negative Emotions in Patients With Chronic Pain: A Systematic Review.","authors":"David Attali,&nbsp;Floriane Leguay,&nbsp;Lola Milcent,&nbsp;Carolina Baeza-Velasco","doi":"10.1097/AJP.0000000000001128","DOIUrl":"https://doi.org/10.1097/AJP.0000000000001128","url":null,"abstract":"<p><strong>Objectives: </strong>Chronic pain is a major health problem given its high prevalence and its multiple consequences on the physical and psychological functioning of patients. It is therefore important to determine the relationship between these consequences and pain management strategies such as activity pacing. This review aimed to examine the association between activity pacing and the level of negative emotions in chronic pain. A second objective was to explore sex differences in this association.</p><p><strong>Methods: </strong>A systematic review of the literature was conducted following the PRISMA guidelines. Three independent reviewers used a combination of keywords within four databases to include studies examining the link between pacing and negative emotions in chronic pain.</p><p><strong>Results: </strong>Pacing was associated with less negative emotions when measured using multidimensional tools, distinguishing it from avoidance, and highlighting the major components of pacing, such as maintaining a constant activity or conserving energy. Data did not allow examination of sex differences.</p><p><strong>Discussion: </strong>Pacing is multidimensional and consists of various strategies of pain management which are not equally associated with negative emotions. It is important to use measures reflecting this conception to strengthen knowledges about the role of pacing in the development of negative emotions.</p>","PeriodicalId":50678,"journal":{"name":"Clinical Journal of Pain","volume":"39 8","pages":"426-435"},"PeriodicalIF":2.9,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10237445","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mindfulness Combined With Exercise Online (MOVE) Compared With a Self-management Guide for Adults With Chronic Pain: A Feasibility Randomized Controlled Trial.","authors":"Orla Deegan,&nbsp;Brona M Fullen,&nbsp;Maire-Brid Casey,&nbsp;Ricardo Segurado,&nbsp;Conor Hearty,&nbsp;Catherine Doody","doi":"10.1097/AJP.0000000000001126","DOIUrl":"https://doi.org/10.1097/AJP.0000000000001126","url":null,"abstract":"<p><strong>Objective: </strong>Limited studies exist combining mindfulness-based stress reduction (MBSR) and exercise in a pain management programme (PMP), with none thus far delivering a combined intervention as an online PMP. This study aimed to explore the acceptability and feasibility of a combined MBSR and exercise online PMP for adults with chronic pain and to examine the feasibility of conducting a randomized controlled trial (RCT) comparing MBSR and exercise delivered online with an online self-management guide.</p><p><strong>Materials and methods: </strong>A feasibility RCT was conducted with participants randomized into the MOVE group (8-wk MBSR and exercise live online) or the self-management (SM) group (8-wk online self-management guide). Primary outcomes included recruitment, attrition, intervention adherence, and satisfaction. Participants wore a Fitbit watch during the study and completed patient-reported outcome measures at baseline, postintervention, and 12-week follow-up.</p><p><strong>Results: </strong>Ninety-six participants were randomized and 80 (83.3%) completed the interventions. Higher mean satisfaction (Client Satisfaction Questionnaire-8) was reported in the MOVE group 26.2 (±5.5) than the SM group 19.4 (±5.6). The Patient Global Impression of Change scale showed favourable changes in both groups; 65.1% of the MOVE group, 42.3% of the SM group reporting improvement. Seventy-three participants (76.3%) adhered to wearing the Fitbit for 8 weeks. Comparable improvements postintervention and at a 12-week follow-up were noted within both groups for Brief Pain Inventory, Pain Self-Efficacy Questionnaire, Pain Disability Index, Pain Catastrophising Scale, Fear Avoidance Belief Questionnaire and Short Form-36 Health Survey.</p><p><strong>Discussion: </strong>The findings suggest both interventions explored are acceptable and feasible. A fully powered RCT examining the effectiveness of MBSR combined with exercise, delivered live online is warranted.</p>","PeriodicalId":50678,"journal":{"name":"Clinical Journal of Pain","volume":"39 8","pages":"394-407"},"PeriodicalIF":2.9,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9861055","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Identification and Characterization of Pain Processing Patterns Among Patients With Chronic Primary Pain: A Replication.","authors":"Alina Scheidegger,&nbsp;Joshua Jäger,&nbsp;Larissa T Blättler,&nbsp;Selma Aybek,&nbsp;Nina Bischoff,&nbsp;Martin Grosse Holtforth","doi":"10.1097/AJP.0000000000001130","DOIUrl":"https://doi.org/10.1097/AJP.0000000000001130","url":null,"abstract":"<p><strong>Objectives: </strong>To develop individual and effective treatment plans for patients with chronic pain, we aimed to replicate Grolimund and colleagues' empirical categorization of chronic pain patients on a new and larger sample. Moreover, this work aimed to extend previous knowledge by considering various treatment outcomes and exploratorily analyzing which coping skills might be particularly relevant for treatment success in each subtype.</p><p><strong>Materials and methods: </strong>Latent class analysis was used to identify homogenous subtypes with different pain processing patterns using the pain processing questionnaire (FESV).</p><p><strong>Results: </strong>By analyzing 602 inpatients with chronic primary pain, we identified 3 subtypes: (1) severely burdened individuals with low coping skills , (2) mildly burdened individuals with high coping skills , and (3) moderately burdened individuals with moderate coping skills. Pain interference, psychological distress, and cognitive and behavioral coping skills improved after treatment in all subtypes. Pain-related mental interference significantly improved only in subtypes (1) and (3). Only individuals of subtype (3) reported significant reductions in pain intensity after treatment. Exploratory regression analysis suggested that of subtype (1), the most promising targets in reducing pain interference and psychological distress posttreatment might be to foster relaxation techniques, counteractive activities, and cognitive restructuring . None of the FESV dimensions significantly predicted treatment outcomes among individuals of subtype (2). Individuals of subtype (3) might benefit the most from experiencing more competence during treatment.</p><p><strong>Discussion: </strong>Our findings highlight the importance of identifying and characterizing subtypes of chronic primary pain patients and that these subtypes should be considered for individualized and effective treatment.</p>","PeriodicalId":50678,"journal":{"name":"Clinical Journal of Pain","volume":"39 8","pages":"414-425"},"PeriodicalIF":2.9,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/d0/7b/ajp-39-414.PMC10353533.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9861061","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pain Management Interventions for the Treatment of Chronic Low Back Pain: A Systematic Review and Meta-Analysis.","authors":"Nagy Mekhail,&nbsp;Sam Eldabe,&nbsp;Erin Templeton,&nbsp;Shrif Costandi,&nbsp;Richard Rosenquist","doi":"10.1097/AJP.0000000000001116","DOIUrl":"https://doi.org/10.1097/AJP.0000000000001116","url":null,"abstract":"<p><strong>Objective: </strong>Determine the relative effectiveness and safety profiles of percutaneous and minimally invasive interventions for chronic low back pain.</p><p><strong>Methods: </strong>A systematic search was performed for randomized controlled trials published in the past 20 years reporting on radiofrequency ablation of the basivertebral, disk annulus and facet nerve structures, steroid injection of the disk, facet joint, and medial branch, biological therapies, and multifidus muscle stimulation. Outcomes evaluated included Visual Analog Scale (VAS) pain scores, Oswestry Disability Index (ODI) scores, quality of life (SF-36 and EQ-5D) scores, and serious adverse event (SAE) rates. Basivertebral nerve (BVN) ablation was chosen as the subject of comparison to all other therapies using a random-effects meta-analysis.</p><p><strong>Results: </strong>Twenty-seven studies were included. BVN ablation was found to provide statistically significant improvements in VAS and ODI scores for 6-, 12- and 24-month follow-up ( P ≤0.05). Biological therapy and multifidus muscle stimulation were the only 2 treatments with both VAS and ODI outcomes not significantly different from BVN ablation at 6-, 12-, and 24-month follow-up. All outcomes found to be statistically significant represented inferior results to those of BVN ablation. Insufficient data precluded meaningful comparisons of SF-36 and EQ-5D scores. The SAE rates for all therapies and all reported time points were not significantly different from BVN ablation except for biological therapy and multifidus muscle stimulation at the 6-month follow-up.</p><p><strong>Conclusions: </strong>BVN ablation, biological therapy, and multifidus stimulation all provide significant, durable improvements in both pain and disability compared with other interventions, which provided only short-term pain relief. Studies on BVN ablation reported no SAEs, a significantly better result than for studies of biological therapy and multifidus stimulation.</p>","PeriodicalId":50678,"journal":{"name":"Clinical Journal of Pain","volume":"39 7","pages":"349-364"},"PeriodicalIF":2.9,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9683486","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Use of a Standard Predetermined Quantitative Parameter to Signal the Need for Rescue Analgesics.","authors":"Rajasekar Ramadurai,&nbsp;Chitra Rajeswari Thangaswamy,&nbsp;Santhosh Arulprakasam,&nbsp;Banupriya Ravichandrane","doi":"10.1097/AJP.0000000000001121","DOIUrl":"https://doi.org/10.1097/AJP.0000000000001121","url":null,"abstract":"","PeriodicalId":50678,"journal":{"name":"Clinical Journal of Pain","volume":"39 7","pages":"365"},"PeriodicalIF":2.9,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10039602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Long-term Efficacy of Pectoserratus Plane Block (PSPB) for Prevention of Post-mastectomy Pain Syndrome: Extended Follow-up From a Randomized Controlled Trial.","authors":"Fabrício T Mendonça,&nbsp;Larissa Ferreira Cunha Nascimento,&nbsp;Nathalia Mundoco Veloso,&nbsp;Gabriela Cavalcante Pires Basto","doi":"10.1097/AJP.0000000000001118","DOIUrl":"https://doi.org/10.1097/AJP.0000000000001118","url":null,"abstract":"<p><strong>Objectives: </strong>Pectoserratus plane block (PSPB) leads to lower postoperative pain intensity. We examined whether PSPB could also reduce the incidence of post-mastectomy pain syndrome (PMPS) in women undergoing breast cancer surgery.</p><p><strong>Methods: </strong>We performed an extension study of a randomized trial that compared PSPB versus control in women undergoing mastectomy. The primary outcome was any chronic pain at the surgical site or adjacent areas, defined as persistent/recurrent pain lasting ≥3 months. Secondary outcomes included neuropathic pain (score ≥4 in the Douleur Neuropathique 4 questionnaire), use of analgesic/anti-inflammatory drugs, pain intensity through the short-form McGill Pain Questionnaire, and type, frequency, and location of the pain.</p><p><strong>Results: </strong>Of the 60 patients that completed the 24-hour follow-up (short-term trial), 53 (88%) completed the long-term follow-up (27 in the PSPB group and 26 in the placebo group). Six of 27 patients (22%) in the PSPB group and 17 of 26 patients (65%) in the placebo group reported any chronic pain (relative risk [RR], 0.34; 95% confidence interval [95% CI]=0.16-0.73, P =0.005). The risk of neuropathic pain was also lower in the PSPB group than in the placebo group (18.5% vs. 54%, respectively; RR, 0.34; 95% CI=0.14-0.82, P =0.02). There were no differences regarding all other pain-related outcomes considering the patients who developed PMPS.</p><p><strong>Discussion: </strong>The results suggest that, in the long term, PSPB-treated participants were associated with a statistically significantly lower risk of PMPS than those who received standard general anesthesia.</p><p><strong>Trial registration: </strong>ClinicalTrials.gov (NCT03966326).</p>","PeriodicalId":50678,"journal":{"name":"Clinical Journal of Pain","volume":"39 7","pages":"334-339"},"PeriodicalIF":2.9,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9673948","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Adolescents and Young Adults With Sickle Cell Disease: Nociplastic Pain and Pain Catastrophizing as Predictors of Pain Interference and Opioid Consumption.","authors":"Clare Kuisell, Robert Ploutz-Snyder, David A Williams, Terri Voepel-Lewis, Raymond J Hutchinson, Katherine M Dudding, Celia Bridges, Ellen M Lavoie Smith","doi":"10.1097/AJP.0000000000001119","DOIUrl":"10.1097/AJP.0000000000001119","url":null,"abstract":"<p><strong>Objectives: </strong>Some patients with sickle cell disease (SCD) have features of nociplastic pain. While research suggests that many patients with nociplastic pain consume more opioids due to opioid nonresponsiveness, little is known about the impact of nociplastic pain and pain catastrophizing on opioid consumption and pain interference among adolescents and young adults (AYA) with SCD. The purpose of this study was to (1) characterize nociplastic pain and pain catastrophizing among AYA with SCD, and (2) determine whether these characterizations are associated with subsequent opioid consumption and pain interference 1 month after characterization.</p><p><strong>Methods: </strong>Participants completed surveys characterizing nociplastic pain and catastrophizing at a routine clinic visit (baseline). Thereafter, participants received weekly text messages that included pain interference and opioid consumption surveys. Multipredictor 2-part models were used to evaluate the predictive relationships between baseline characterizations and subsequent pain interference, and opioid consumption.</p><p><strong>Results: </strong>Forty-eight AYA aged 14 to 35 completed baseline measures. Twenty-five percent of participants had scores suggestive of nociplastic pain. Greater nociplastic pain features significantly increased the odds of consuming opioids (odds ratio=1.2) and having greater interference from pain (odds ratio=1.46). Regression analyses found that greater baseline nociplastic pain characteristics were significantly associated with opioid consumption (β=0.13) and pain interference (β=0.061); whereas higher pain catastrophizing scores predicted less opioid consumption (β=-0.03) and less pain interference (β=-0.0007).</p><p><strong>Discussion: </strong>In this sample of AYA with SCD, features of nociplastic pain predicted higher subsequent opioid consumption and pain interference. Being aware of nociplastic pain features in patients with SCD may better guide individualized pain management.</p>","PeriodicalId":50678,"journal":{"name":"Clinical Journal of Pain","volume":"39 7","pages":"326-333"},"PeriodicalIF":2.6,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10330104/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10129994","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}